product monograph nitroglycerin in 5
... Intravenous nitroglycerin reduced central venous pressure (CVP), right arterial pressure (RAP), pulmonary arterial pressure (PAP), pulmonary-capillary wedge pressure (PCWP), pulmonary vascular resistance (PVR), and systemic vascular resistance (SVR). When these parameters were elevated, reducing th ...
... Intravenous nitroglycerin reduced central venous pressure (CVP), right arterial pressure (RAP), pulmonary arterial pressure (PAP), pulmonary-capillary wedge pressure (PCWP), pulmonary vascular resistance (PVR), and systemic vascular resistance (SVR). When these parameters were elevated, reducing th ...
Detection of Intracardiac and Intrapulmonary Shunts
... every TEE and intracardiac shunt pathways are often easily identified as contrast passes through them. Patient sedation can prevent adequate Valsalva maneuvers during TEE so right-to-left shunts across a patent foramen ovale may go undetected (Fisher et al., 1995). 3.3 Differentiating between intrap ...
... every TEE and intracardiac shunt pathways are often easily identified as contrast passes through them. Patient sedation can prevent adequate Valsalva maneuvers during TEE so right-to-left shunts across a patent foramen ovale may go undetected (Fisher et al., 1995). 3.3 Differentiating between intrap ...
Cardiomyocyte NF-kB p65 promotes adverse remodelling, apoptosis
... subunit composition by EMSA and gel supershifts in nuclear extracts (NEs) from wild-type (WT) sham and HF hearts. p50(1) and p50(2) indicate two different NF-kB p50 subunit-specific antibodies used in gel supershifts. Arrowhead, p65 supershift; arrow, RelB supershift. (B) NF-kB p65 and p50 subunit-s ...
... subunit composition by EMSA and gel supershifts in nuclear extracts (NEs) from wild-type (WT) sham and HF hearts. p50(1) and p50(2) indicate two different NF-kB p50 subunit-specific antibodies used in gel supershifts. Arrowhead, p65 supershift; arrow, RelB supershift. (B) NF-kB p65 and p50 subunit-s ...
Improved Left Ventricular Relaxation During Short
... pacing, indicating more favorable left ventricular relaxation. This benefit could be attributed to shorter intraventricular conduction times during outflow tract pacing, evidenced by shorter QRS complexes. Previous studies20 –22 have shown that indexes of isovolumic relaxation are independent of loa ...
... pacing, indicating more favorable left ventricular relaxation. This benefit could be attributed to shorter intraventricular conduction times during outflow tract pacing, evidenced by shorter QRS complexes. Previous studies20 –22 have shown that indexes of isovolumic relaxation are independent of loa ...
The Heartbreak of Not Making Automated External Defibrillators
... believe that the AED should be able to increase its electrical jolt if the charge is unsuccessful with the initial application.50 It must be noted, however, that the AED is not designed for a person who has flat-lined. 51 That victim can only be resuscitated by CPR and cardiac drugs.52 Studies have ...
... believe that the AED should be able to increase its electrical jolt if the charge is unsuccessful with the initial application.50 It must be noted, however, that the AED is not designed for a person who has flat-lined. 51 That victim can only be resuscitated by CPR and cardiac drugs.52 Studies have ...
Cardiac Resynchronization Therapy Defibrillator
... electrical signals. These signals travel through the electrical pathways of your heart (Figure 1), causing the muscle contraction that pumps blood throughout your body. Normally these signals come from a small area in your heart called the sinoatrial (SA) node. This area is located in the upper righ ...
... electrical signals. These signals travel through the electrical pathways of your heart (Figure 1), causing the muscle contraction that pumps blood throughout your body. Normally these signals come from a small area in your heart called the sinoatrial (SA) node. This area is located in the upper righ ...
Cachexia and Sarcopenia: Emerging Syndromes of Importance in
... Whereas obesity is a risk factor for development of heart disease in people, obesity actually may be associated with a protective effect once heart failure is present—this is known as the obesity paradox.23 This is a relatively recently identified phenomenon but the evidence has rapidly grown. A recen ...
... Whereas obesity is a risk factor for development of heart disease in people, obesity actually may be associated with a protective effect once heart failure is present—this is known as the obesity paradox.23 This is a relatively recently identified phenomenon but the evidence has rapidly grown. A recen ...
American College of Cardiology/European Society of Cardiology
... present.1,5,7,36 Although the usual clinical diagnostic criteria for HCM is a maximal wall thickness greater than or equal to 15 mm, genotype-phenotype correlations have shown that virtually any wall thickness (including those within normal range) are compatible with the presence of a HCM mutant gen ...
... present.1,5,7,36 Although the usual clinical diagnostic criteria for HCM is a maximal wall thickness greater than or equal to 15 mm, genotype-phenotype correlations have shown that virtually any wall thickness (including those within normal range) are compatible with the presence of a HCM mutant gen ...
Ambulatory blood pressure monitoring
... deferred in patients with white-coat hypertension confirmed by ABP monitoring (although they require monitoring and lifestyle management of BP). In patients with hypertension who also show an additional white-coat effect during clinic BP measurements, confirmation of actual BP profile by ABP monitor ...
... deferred in patients with white-coat hypertension confirmed by ABP monitoring (although they require monitoring and lifestyle management of BP). In patients with hypertension who also show an additional white-coat effect during clinic BP measurements, confirmation of actual BP profile by ABP monitor ...
Epicardial Fat and Atrial Fibrillation: A Review
... the epicardial adipose tissue can act locally in a paracrine fashion or can act downstream when secreted into the vasa vasorum. Zhou et al. studied samples of pericardial fat from patients undergoing coronary artery bypass graft surgery as compared to samples from epicardial fat in non-CAD patients ...
... the epicardial adipose tissue can act locally in a paracrine fashion or can act downstream when secreted into the vasa vasorum. Zhou et al. studied samples of pericardial fat from patients undergoing coronary artery bypass graft surgery as compared to samples from epicardial fat in non-CAD patients ...
Flecainide: Current status and perspectives in arrhythmia
... rapidly without any significant interactions with food or antacid. Its bioavailability is around 90%, indicating no significant first pass effect through the liver. In normal subjects, plasma peak levels are reached after 2-3 h and steady state levels within 3-5 d. The half-life of flecainide ranges ...
... rapidly without any significant interactions with food or antacid. Its bioavailability is around 90%, indicating no significant first pass effect through the liver. In normal subjects, plasma peak levels are reached after 2-3 h and steady state levels within 3-5 d. The half-life of flecainide ranges ...
Print - Circulation
... the z direction was perpendicular to this plane. The z value of each tomographic slice was taken as the value at the center of the 8-mm-thick slice. The long axis defined at end systole was used as a common axis for both end diastole and end systole. This was important for optimal matching of region ...
... the z direction was perpendicular to this plane. The z value of each tomographic slice was taken as the value at the center of the 8-mm-thick slice. The long axis defined at end systole was used as a common axis for both end diastole and end systole. This was important for optimal matching of region ...
Cardiology
... conference coverage thought leader perspectives medical journal articles and more from theheart org and medscape, cardiologists 2017 cardiology conferences global events - meet cardiologists physicians cardiac surgeons and other health care professionals from europe usa middle east asia pacific fran ...
... conference coverage thought leader perspectives medical journal articles and more from theheart org and medscape, cardiologists 2017 cardiology conferences global events - meet cardiologists physicians cardiac surgeons and other health care professionals from europe usa middle east asia pacific fran ...
Methodological approach to the first and second lactate threshold in
... and by additional CO2 stemming from lactic acid buffering [18]. The ‘second ventilatory threshold’ (VT2) [7,32] is demonstrated by the second break point in the three-line regression of VE versus WL. Respiratory gas exchange ratio versus workload The RER is the ratio of CO2 output and O2 uptake (VCO ...
... and by additional CO2 stemming from lactic acid buffering [18]. The ‘second ventilatory threshold’ (VT2) [7,32] is demonstrated by the second break point in the three-line regression of VE versus WL. Respiratory gas exchange ratio versus workload The RER is the ratio of CO2 output and O2 uptake (VCO ...
Left ventricular twist and untwist rate provide reliable measures of
... Proper electrode position was confirmed by ensuring that volume waveforms were obtained from each individual pair of electrodes on the catheter. LV volume was calculated by injecting a hypertonic saline (0.2 g NaCl/mL, 2 mL) into the right atrium to obtain a constant offset volume (Vc). We measured ...
... Proper electrode position was confirmed by ensuring that volume waveforms were obtained from each individual pair of electrodes on the catheter. LV volume was calculated by injecting a hypertonic saline (0.2 g NaCl/mL, 2 mL) into the right atrium to obtain a constant offset volume (Vc). We measured ...
2011 Guideline Slides PCI - American College of Cardiology
... Classification of Recommendations and Levels of Evidence A recommendation with Level of Evidence B or C does not imply that the recommendation is weak. Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable ...
... Classification of Recommendations and Levels of Evidence A recommendation with Level of Evidence B or C does not imply that the recommendation is weak. Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable ...
PCI in Specific Clinical Situations - Journal of the American College
... Classification of Recommendations and Levels of Evidence A recommendation with Level of Evidence B or C does not imply that the recommendation is weak. Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable ...
... Classification of Recommendations and Levels of Evidence A recommendation with Level of Evidence B or C does not imply that the recommendation is weak. Many important clinical questions addressed in the guidelines do not lend themselves to clinical trials. Although randomized trials are unavailable ...
syncope: diagnosis and treatment – marc kraus
... The definition of neurally mediated syncope (NMS) is: The development of arterial vasodilatation in the setting of relative or absolute bradycardia. Usually, bradycardia is expected with cardiogenic syncope. However, vasodepressor syncope (ie carotid-sinus hypersensitivity) is defined as a pure vaso ...
... The definition of neurally mediated syncope (NMS) is: The development of arterial vasodilatation in the setting of relative or absolute bradycardia. Usually, bradycardia is expected with cardiogenic syncope. However, vasodepressor syncope (ie carotid-sinus hypersensitivity) is defined as a pure vaso ...
Contemporary Pacemakers - CCM, University of Pittsburgh
... The association between long-term right ventricular apical pacing and pathological changes and increased morbidity is increasingly recognized.23-25 Thus, ventricular dyssynchrony arising from right ventricular apical pacing may cause cardiac dysfunction and heart failure.26-33 Avoidance of right ven ...
... The association between long-term right ventricular apical pacing and pathological changes and increased morbidity is increasingly recognized.23-25 Thus, ventricular dyssynchrony arising from right ventricular apical pacing may cause cardiac dysfunction and heart failure.26-33 Avoidance of right ven ...
Document
... aggregates within the LV wall.1,2 However, accurate evaluation of radial motion is equally important. For example, radial wall motion abnormalities have been detected in patients with diabetes3 and hypertrophic cardiomyopathy,4 whereas radial dyssynchrony is almost universal in patients with heart f ...
... aggregates within the LV wall.1,2 However, accurate evaluation of radial motion is equally important. For example, radial wall motion abnormalities have been detected in patients with diabetes3 and hypertrophic cardiomyopathy,4 whereas radial dyssynchrony is almost universal in patients with heart f ...
60 Years of Making Hearts Beat - Institut de Cardiologie de Montréal
... demonstration of the commitment of MHI doctors and employees to this institution they have helped grow and of the Quebec community’s dedication to an institution that has been a source of pride for 60 years. This year has given us an opportunity to celebrate in a manner befitting our incredible 60-y ...
... demonstration of the commitment of MHI doctors and employees to this institution they have helped grow and of the Quebec community’s dedication to an institution that has been a source of pride for 60 years. This year has given us an opportunity to celebrate in a manner befitting our incredible 60-y ...
Cardiac sympathetic innervation via middle cervical and stellate
... channelopathies, including long QT syndrome and catecholaminergic polymorphic ventricular tachycardia, who have structurally normal hearts (4, 17, 38). In a small series of patients with structural heart disease, bilateral CSD has shown promise in reducing the burden of internal cardioverter defibri ...
... channelopathies, including long QT syndrome and catecholaminergic polymorphic ventricular tachycardia, who have structurally normal hearts (4, 17, 38). In a small series of patients with structural heart disease, bilateral CSD has shown promise in reducing the burden of internal cardioverter defibri ...
Shear properties of passive ventricular myocardium - AJP
... software was written using the LabView (National Instruments) programming language. Shear testing. Before testing, the dimensions of each myocardial block were measured using a micrometer. Absorbent paper soaked with a small drop of cyanoacrylate adhesive was used to attach the samples to the upper ...
... software was written using the LabView (National Instruments) programming language. Shear testing. Before testing, the dimensions of each myocardial block were measured using a micrometer. Absorbent paper soaked with a small drop of cyanoacrylate adhesive was used to attach the samples to the upper ...
Myocardial infarction
Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Often it is in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat, or feeling tired. About 30% of people have atypical symptoms, with women more likely than men to present atypically. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, or cardiac arrest.Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol intake, among others. The mechanism of an MI often involves the rupture of an atherosclerotic plaque, leading to complete blockage of a coronary artery. MIs are less commonly caused by coronary artery spasms, which may be due to cocaine, significant emotional stress, and extreme cold, among others. A number of tests are useful to help with diagnosis, including electrocardiograms (ECGs), blood tests, and coronary angiography. An ECG may confirm an ST elevation MI if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB.Aspirin is an appropriate immediate treatment for a suspected MI. Nitroglycerin or opioids may be used to help with chest pain; however, they do not improve overall outcomes. Supplemental oxygen should be used in those with low oxygen levels or shortness of breath. In ST elevation MIs treatments which attempt to restore blood flow to the heart are typically recommended and include angioplasty, where the arteries are pushed open, or thrombolysis, where the blockage is removed using medications. People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use angioplasty in those at high risk. In people with blockages of multiple coronary arteries and diabetes, bypass surgery (CABG) may be recommended rather than angioplasty. After an MI, lifestyle modifications, along with long term treatment with aspirin, beta blockers, and statins, are typically recommended.Worldwide, more than 3 million people have ST elevation MIs and 4 million have NSTEMIs each year. STEMIs occur about twice as often in men as women. About one million people have an MI each year in the United States. In the developed world the risk of death in those who have had an STEMI is about 10%. Rates of MI for a given age have decreased globally between 1990 and 2010.