Lineage origins of GABAergic versus glutamatergic neurons in the
... likely represent different progenitor states along a developmental time line rather than separate fate-restricted lineages. Similarly, in vitro and in vivo lineage tracing experiments have shown that the vast majority of neocortical progenitor cells either generate neurons or glia [2]. This heteroge ...
... likely represent different progenitor states along a developmental time line rather than separate fate-restricted lineages. Similarly, in vitro and in vivo lineage tracing experiments have shown that the vast majority of neocortical progenitor cells either generate neurons or glia [2]. This heteroge ...
NEUROGENESIS IN THE ANTERIOR OLFACTORY NUCLEUS AND
... Since neurogenesis in the rat olfactory peduncle extends beyond birth, both prenatal and postnatal developmental series were used. All series contained groups of Purdue-Wistar rats given successive daily (between 9 and 11 a.m.) s.c. injections of [3H]thymidine (Schwarz-Mann; sp. act. 6.0 Ci/mM; 5 ix ...
... Since neurogenesis in the rat olfactory peduncle extends beyond birth, both prenatal and postnatal developmental series were used. All series contained groups of Purdue-Wistar rats given successive daily (between 9 and 11 a.m.) s.c. injections of [3H]thymidine (Schwarz-Mann; sp. act. 6.0 Ci/mM; 5 ix ...
Document
... Research in Dr. Jaffe’s lab focuses on the hippocampal formation; a brain region important for certain aspects of learning and memory. It is also one of the first brain structures affected by Alzheimer's disease and medial temporal lobe epilepsy arises in the hippocampus, among other brain structure ...
... Research in Dr. Jaffe’s lab focuses on the hippocampal formation; a brain region important for certain aspects of learning and memory. It is also one of the first brain structures affected by Alzheimer's disease and medial temporal lobe epilepsy arises in the hippocampus, among other brain structure ...
Ramayya, A. G., Zaghloul, K. A., Weidemann, C. T., Baltuch, G. H.
... activity using the WaveClus software package (Quiroga et al., 2005). We band-pass filtered each voltage recording from 400 to 5000 Hz and manually removed periods of motion artifact. We identified spike events as positive or negative deflections in the voltage trace that crossed a threshold that was ...
... activity using the WaveClus software package (Quiroga et al., 2005). We band-pass filtered each voltage recording from 400 to 5000 Hz and manually removed periods of motion artifact. We identified spike events as positive or negative deflections in the voltage trace that crossed a threshold that was ...
Stress and Glucocorticoids Affect the Expression of Brain
... hippocampus as well as in other specific brain nuclei. BDNF is found throughout the adult brain in concentrations 50 times higher than NGF itself and may be trophic for a wide variety of neurons (Hofer et al., 1990; Maisonpierre et al., 1990a; Phillips et al., 1990; DiStefano et al., 1992; Ip et al. ...
... hippocampus as well as in other specific brain nuclei. BDNF is found throughout the adult brain in concentrations 50 times higher than NGF itself and may be trophic for a wide variety of neurons (Hofer et al., 1990; Maisonpierre et al., 1990a; Phillips et al., 1990; DiStefano et al., 1992; Ip et al. ...
Diversity of reporter expression patterns in transgenic mouse lines
... Diversity of reporter-expressing neurons in the hypothalamus and median eminence of transgenic Validation of the anti-CRH serum and expression mice pattern of the peptide in adult mouse Because of the crucial role of hypothalamic CRH in We employed here the antihuman/rat CRH serum initiating the neu ...
... Diversity of reporter-expressing neurons in the hypothalamus and median eminence of transgenic Validation of the anti-CRH serum and expression mice pattern of the peptide in adult mouse Because of the crucial role of hypothalamic CRH in We employed here the antihuman/rat CRH serum initiating the neu ...
Mice Lacking M1 and M3 Muscarinic Acetylcholine Receptors Have
... the discrimination of dissimilar molecules, social odors (e.g., urine) and novel object recognition was not affected. In addition the KO mice showed impaired learning in an associative odor-learning task, learning to discriminate odors at a slower rate, indicating that both short and long-term memor ...
... the discrimination of dissimilar molecules, social odors (e.g., urine) and novel object recognition was not affected. In addition the KO mice showed impaired learning in an associative odor-learning task, learning to discriminate odors at a slower rate, indicating that both short and long-term memor ...
Text S1.
... could have differentiated into an axon. The discrepancy between random choice at 1-2 DIV and axonal preference along L1 at 3 DIV corresponds to failures of polarization along curved lines. It is thus possible to calculate a success probability for a neurite to become an axon when growing over a curv ...
... could have differentiated into an axon. The discrepancy between random choice at 1-2 DIV and axonal preference along L1 at 3 DIV corresponds to failures of polarization along curved lines. It is thus possible to calculate a success probability for a neurite to become an axon when growing over a curv ...
Number, size and distribution of ganglion neurons in urinary bladder
... The mean areas of the urinary bladders, the mean number of neurons and the mean number of ganglia obtained from the three species are presented in Table I, together with the mean area of the nerve cell bodies. While. 2043 neurons per bladder were seen in the Guinea-pig, they were 1593 in the C57/ BL ...
... The mean areas of the urinary bladders, the mean number of neurons and the mean number of ganglia obtained from the three species are presented in Table I, together with the mean area of the nerve cell bodies. While. 2043 neurons per bladder were seen in the Guinea-pig, they were 1593 in the C57/ BL ...
Naturally Occurring Fluctuation in Dendritic
... for this phase of the estrouscycle. These results demonstrate that dendritic spinesare remarkably plastic in that dendritic spine density decreasesby over 30% during approximately 24 hr betweenthe late afternoon of proestrusand late afternoon of estrus(Smith et al., 1975). Dendritic spine density th ...
... for this phase of the estrouscycle. These results demonstrate that dendritic spinesare remarkably plastic in that dendritic spine density decreasesby over 30% during approximately 24 hr betweenthe late afternoon of proestrusand late afternoon of estrus(Smith et al., 1975). Dendritic spine density th ...
Distinct Representations and Theta Dynamics in Dorsal and Ventral
... Two-dimensional firing field plots. For trackbetween first and second halves of the recording session, and information content (Markus et al., 1994). B, Distributions of field ing the position of the animal, two small lightsizes and contour sizes for all neurons. The distributions of dCA3 and vCA3 p ...
... Two-dimensional firing field plots. For trackbetween first and second halves of the recording session, and information content (Markus et al., 1994). B, Distributions of field ing the position of the animal, two small lightsizes and contour sizes for all neurons. The distributions of dCA3 and vCA3 p ...
The fate of Nissl-stained dark neurons following
... [10, 25, 33]. On the other hand, some reports have described the possibility that dark neurons recover from such a damaged status [11, 15, 16]. In the rat lateral Xuid percussion injury (FPI) model, numerous dark neurons are observed in the neocortex and the hippocampus in the early phase after TBI ...
... [10, 25, 33]. On the other hand, some reports have described the possibility that dark neurons recover from such a damaged status [11, 15, 16]. In the rat lateral Xuid percussion injury (FPI) model, numerous dark neurons are observed in the neocortex and the hippocampus in the early phase after TBI ...
optimization of neuronal cultures derived from human induced
... Cell Culture. Post-mitotic human neurons derived from iPSCs (“iCell® Neurons”, Cellular Dynamics International, USA) and primary neuronal cultures isolated from E18 rat embryos were seeded in 96-well plates (Greiner) coated with poly-D-lysine with or without laminin. For some experiments, iCell Neur ...
... Cell Culture. Post-mitotic human neurons derived from iPSCs (“iCell® Neurons”, Cellular Dynamics International, USA) and primary neuronal cultures isolated from E18 rat embryos were seeded in 96-well plates (Greiner) coated with poly-D-lysine with or without laminin. For some experiments, iCell Neur ...
Topical Review
... cortex.41 These differences between PNS and CNS postinjury axonal sprouting may reflect true differences in the molecular response of these two systems, and may account for the limited ability of the CNS to sprout. However, the present gene expression profiling of axonal sprouting after stroke has i ...
... cortex.41 These differences between PNS and CNS postinjury axonal sprouting may reflect true differences in the molecular response of these two systems, and may account for the limited ability of the CNS to sprout. However, the present gene expression profiling of axonal sprouting after stroke has i ...
29.2 Neurons - Cloudfront.net
... • The nervous system works quickly, using chemical and electrical signals. – interconnected network of cells (hardwired) – signals move through cells (neurons) – divided into central nervous system (CNS) and peripheral nervous system (PNS) - CNS- brain and spinal cord - PNS-network of nerves that tr ...
... • The nervous system works quickly, using chemical and electrical signals. – interconnected network of cells (hardwired) – signals move through cells (neurons) – divided into central nervous system (CNS) and peripheral nervous system (PNS) - CNS- brain and spinal cord - PNS-network of nerves that tr ...
Occlusion and brain function: mastication as a prevention of
... subfields in the hippocampus, where spatial encoding is processed, in several ways. It decreases the number of pyramidal neurons (16, 17, 21) and spines (26), and it decreases the amount of synaptic formation (18) and neurotrophic receptor expression (16). The function of the affected neurons is als ...
... subfields in the hippocampus, where spatial encoding is processed, in several ways. It decreases the number of pyramidal neurons (16, 17, 21) and spines (26), and it decreases the amount of synaptic formation (18) and neurotrophic receptor expression (16). The function of the affected neurons is als ...
adult rat spinal cord culture on an organosilane surface in
... In this study, we have documented by morphological analysis, immunocytochemistry, and electrophysiology, the development of a culture system that promotes the growth and long-term survival of dissociated adult rat spinal cord neurons. This system comprises a patternable, nonbiological, cell growth–p ...
... In this study, we have documented by morphological analysis, immunocytochemistry, and electrophysiology, the development of a culture system that promotes the growth and long-term survival of dissociated adult rat spinal cord neurons. This system comprises a patternable, nonbiological, cell growth–p ...
Optimization of neuronal cultures derived from human
... the MANTRA system in an integrated drug discovery platform that targets synaptic transmission at multiple levels. ...
... the MANTRA system in an integrated drug discovery platform that targets synaptic transmission at multiple levels. ...
Neuronal Migration and Ventral Subtype Identity in the
... developing forebrain, Sox1 is expressed throughout the ventricular zone (VZ) and subventricular zone (SVZ) and in neurons around the anterior commissure region, where the prospective nucleus accumbens forms (red arrowheads in Figure 1K and 1M), and in the striatal bridges that link this intermediate ...
... developing forebrain, Sox1 is expressed throughout the ventricular zone (VZ) and subventricular zone (SVZ) and in neurons around the anterior commissure region, where the prospective nucleus accumbens forms (red arrowheads in Figure 1K and 1M), and in the striatal bridges that link this intermediate ...
The neuronal structure of the globus pallidus in the rabbit — Nissl
... The analysis of our material shows the presence of two main types of neurons in the rabbit’s GP: large and small. The first one is represented by large polygonal, triangular and fusiform neurons with thick, long, usually infrequently branched, dendrites. The second one consists of small, mostly roun ...
... The analysis of our material shows the presence of two main types of neurons in the rabbit’s GP: large and small. The first one is represented by large polygonal, triangular and fusiform neurons with thick, long, usually infrequently branched, dendrites. The second one consists of small, mostly roun ...
found that in flight, 3D hippocampal place cells had nearly spherical
... might have evolved in bats because of the pressures to encode and retrieve 3D sensory information. This interpretation also implies possibly different encoding of 3D space in land-dwelling mammals that typically do not move volumetrically in 3D during ontogeny but instead rely mainly on horizontal s ...
... might have evolved in bats because of the pressures to encode and retrieve 3D sensory information. This interpretation also implies possibly different encoding of 3D space in land-dwelling mammals that typically do not move volumetrically in 3D during ontogeny but instead rely mainly on horizontal s ...
On the Significance of Neuronal Giantism in Gastropods
... Although one or more of these characteristics may appear in various gastropod taxa, the appearance of all five may be relatively specific to the opisthobranch/pulmonate line. The gastropods crept into the fossil record around 580 million years ago as minute animals l-2 mm in shell diameter, and toda ...
... Although one or more of these characteristics may appear in various gastropod taxa, the appearance of all five may be relatively specific to the opisthobranch/pulmonate line. The gastropods crept into the fossil record around 580 million years ago as minute animals l-2 mm in shell diameter, and toda ...
Dissecting appetite
... To tease apart the hunger circuits, researchers initially focused on a tiny section of the hypothalamus called the arcuate nucleus. “It’s an amazing structure,” explains Lowell. “It exerts powerful control over hunger.” The region contains two key neurons: AgRP neurons, which sense a fasted state an ...
... To tease apart the hunger circuits, researchers initially focused on a tiny section of the hypothalamus called the arcuate nucleus. “It’s an amazing structure,” explains Lowell. “It exerts powerful control over hunger.” The region contains two key neurons: AgRP neurons, which sense a fasted state an ...
Control of dopaminergic neuron survival by the unfolded protein
... arkinson disease (PD) is part of a group of diseases classified as protein-misfolding disorders (PMDs), which also includes Alzheimer’s disease, Huntington disease, and amyotrophic lateral sclerosis (ALS). PMDs share common pathological features, characterized by the accumulation of abnormal protein ...
... arkinson disease (PD) is part of a group of diseases classified as protein-misfolding disorders (PMDs), which also includes Alzheimer’s disease, Huntington disease, and amyotrophic lateral sclerosis (ALS). PMDs share common pathological features, characterized by the accumulation of abnormal protein ...
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... of cells (Zemelman et al., 2003; Lima and Miesenböck, 2005). When targeted optical activation of dopaminergic neurons in TH-GAL4:UAS-P2X2 flies (Friggi-Grelin et al., 2003; Lima and Miesenböck, 2005) was made contingent upon entry into one odor, an aversive memory specific to that odor indeed form ...
... of cells (Zemelman et al., 2003; Lima and Miesenböck, 2005). When targeted optical activation of dopaminergic neurons in TH-GAL4:UAS-P2X2 flies (Friggi-Grelin et al., 2003; Lima and Miesenböck, 2005) was made contingent upon entry into one odor, an aversive memory specific to that odor indeed form ...