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Group presentations guide 10-4
Group presentations guide 10-4

... of the approximately 3 billion DNA base pairs, or letters, that make up the human genome. With its four-letter language, DNA contains the information needed to build the entire human body. A gene traditionally refers to the unit of DNA that carries the instructions for making a specific protein or s ...
DNA Know your Molecules
DNA Know your Molecules

... Adds short RNA ...
DNA and RNA Review
DNA and RNA Review

... 12. Explain why it is possible for an amino acid to be specified by more than one kind of codon? ...
Answers section 4
Answers section 4

... 6. general transcription factors (includes TAT binding protein – TBP, which binds to the TATA box and recruits the rest of the GTFs) and sequence specific transcription factors 7. introns 8. liver because it has the sequence-specific transcription factors that bind to the upstream portion of the pr ...
compgenomics
compgenomics

... Digital gene expression from RNA-seq studies Prediction of ncRNAs and their function Global mapping of alternative splicing regulation Integration of multi-level signaling (TFs, miRNA, chromatin) Association studies for combinations of alleles ...
What are genomes and how are they studied
What are genomes and how are they studied

... More alternative transcripts: Increased RNA splice variants thereby expanding proteins by 5 fold 2) Proteome: proteome more complex than invertebrates Domain arrangements in human:  largest total number of domains is 130  largest number of domain types per protein is 9  Mostly identical arrangeme ...
DNA Function: Information Transmission
DNA Function: Information Transmission

... 18.3: Noncoding RNAs play multiple roles in controlling gene expression ● genome sequencing has shown that protein-coding DNA only accounts for 1.5% of the human genome (& other eukaryotes) ● a small fraction of the non-protein coding DNA consists of genes for rRNAs and tRNAs ● until recently, resea ...
Non-coding RNA
Non-coding RNA

... Transient and levels correlate with enhancer activities Functions unknown Kim et al., Nature 465,182–187(2010). ...
chap12studyguide
chap12studyguide

... 18. After introns are cut out of an RNA molecule, the remaining ____________________ are spliced back together to form the final messenger RNA. 19. A mutation in a series of genes, called the ____________________, can change the organs that develop in specific parts of an embryo. Short Answer 20. Wh ...
Messenger RNA profiling: a prototype method to supplant
Messenger RNA profiling: a prototype method to supplant

... Why use mRNA to identify body fluids? ...
Summary - EUR RePub
Summary - EUR RePub

... acts in trans, i.e. it requires molecules separate from the gene containing DNA molecule, here referred to as trans-acting factors. Despite the fact that cis-regulatory DNA elements have different functional definitions, there are two features that they have in common: they can be detected as DNase ...
second of Chapter 10: RNA processing
second of Chapter 10: RNA processing

... • The poly(A) tail is added by poly(A) polymerase. • About 200 adenosines are added to the 3’ end of the primary transcript. • Poly(A) tails help geneticists isolate mRNAs from cells. ...
Nuclear Genes
Nuclear Genes

... Image from: An Introduction To Human Molecular Genetics Second Edition by Jack J. Pasternak, Published by John Wiley & Sons, Inc., Hoboken, ...
Simple tandem repeats in mammalian genomes
Simple tandem repeats in mammalian genomes

... Caenorhabditis elegans with its more than 19,000 genes or the fruit fly Drosophila melanogaster with about 13,000 genes. This led to the assumption that the difference between humans and other organisms is not so much due the number of genes, but more to how these genes function. DNA molecules are m ...
ALE #7
ALE #7

... e. Enhancers – these are sections of DNA that play a role in the regulation of gene expression. When activator proteins bind to enhancers, they assist other transcription factors to bind to RNA polymerase. This helps to promote transcription 2. Please describe how each of the following processes exe ...
Dicer-Like
Dicer-Like

... What is Dicer’s role in RNAi? • Activated by exogenous double-stranded (ds) RNA • miRNA (micro RNA) -small, non-coding regions of double-stranded (ds) RNA 21-22 nucleotides ...
Central Dogma.pptx
Central Dogma.pptx

... DNA’s message (gene) is expressed (turned on) by first being transcribed into RNA (mRNA, tRNA or rRNA) mRNA=messenger RNA, carries DNA’s message to be later translated into proteins with the help of tRNA and the ribosome. ...
gene regulation
gene regulation

... (enzymes in glycolysis) • Inducible – off but can be switched on • Repressible – on but can be switched off ...
Eukaryotic RNA Polymerases and their Promoters
Eukaryotic RNA Polymerases and their Promoters

... • General architecture of the promoter is well conserved – two elements: – Core element surrounding transcription start site – Upstream promoter element (UPE) 100 bp farther upstream – Spacing between these elements is important ...
Dr. Chris Eskiw Dept. of Food and Bioproduct Sciences University of Saskatchewan
Dr. Chris Eskiw Dept. of Food and Bioproduct Sciences University of Saskatchewan

... what we are and how we function at the molecular level. Although this project did provide very useful and insightful information, the primary sequence of our genome is just the first level regulating function (gene expression). Numerous examples demonstrate that genome folding (organization in 3D sp ...
Presentation
Presentation

... unless an inducer is present  Inducer attaches to the repressor and causes it to move so that transcription can occur ...
m10-expression
m10-expression

... Proteins/metabolites hard to measure, but RNA provides a more uniform intermediate. Transcriptional measurements provide the ability to: Associate genes with biological processes / environmental conditions / stimuli / chemistry / regulation / etc. Diagnostic / prognostic biomarker for human (or othe ...
presentation source
presentation source

... – Ensure that correct genes are expressed in development ...
This examination paper consists of 4 pages
This examination paper consists of 4 pages

... occur in prokaryotes and in eukaryotes transpose conservatively code for a transposase enzyme ...
Eukaryotes - Daniel Guetta
Eukaryotes - Daniel Guetta

... The low activity of basal promoters is greatly increased by the presence of other elements located UPSTREAM of the promoter ...
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Short interspersed nuclear elements (SINEs)

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