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Regulation of Gene Expression
Regulation of Gene Expression

... -whether a gene is active or inactive -determines the level of activity and the amount of protein that is available. ...
How Proteins are Made
How Proteins are Made

... V. Gene Regulation and Structure A. Gene Regulation Prokaryotic and eukaryotic cells are able to control which genes are decoded and which are not. B. Protein Synthesis in Prokaryotes 1. In prokaryotes, gene expression is regulated by operons. 2. Gene expression is switched off when repressor pro ...
Review L14 Gene to Protein L15 Gene Reg
Review L14 Gene to Protein L15 Gene Reg

... 13. What happens to the polypeptide chain after it is synthesized? 14. How do proteins that should be made in the ER get to the ER? 15. Make a list of all the different types of RNA and their functions. 16. What is a mutation? 17. What is a point mutation? 18. Distinguish between the following types ...
Elucidating Principles of Gene Regulation from Stochastic Models
Elucidating Principles of Gene Regulation from Stochastic Models

... The complexity of multicellular organisms arises largely from reusing many of the same genes in numerous combinations, rather than by the introduction of novel genes for each new celltype. Put another way, what makes you human is not so much which genes you have but how you use them. The instruction ...
Know your molecules organizer
Know your molecules organizer

... Adds deoxyribonucleotides to the 3’ end of an existing chain Removes RNA primers and replaces them with deoxyribonucleotides Joins Okazaki fragments on the lagging ...
Interferon-lambda and therapy for chronic hepatitis C virus infection
Interferon-lambda and therapy for chronic hepatitis C virus infection

... elements (IBEs) that provide binding sites for phosphorylated IRF3 and/or IRF7. Similar binding sites are also present in the promoters of the IFN- λ genes . Therefore, it appears that the same set of transcription factors that regulate IFNB transcription also control expression of the IFN- genes. F ...
Chapter 22
Chapter 22

... Some retroposons directly resemble retroviruses in their use of LTRs, whereas others do not have LTRs. Other elements can be found that were generated by an RNA-mediated transposition event, but they do not themselves code for enzymes that can catalyze transposition. Transposons and retroposons cons ...
APBio-StudyGuide-Ch18
APBio-StudyGuide-Ch18

... the potential locations for gene expression regulation in eukaryotic cells. How does this compare with prokaryotic cells? ...
Chapter 19: Control of Gene Expression in Eukaryotes
Chapter 19: Control of Gene Expression in Eukaryotes

... 9.) What is a transcriptional enhancer? How enhancers in the DNA work from such far distances? Lecture 26 “Control of Gene Expression in Eukaryotes: Part 2” PPT Review 1.) Is the final mature mRNA transcript composed of exons or introns? What occurs during splicing of primary mRNAs? 2.) What is alte ...
Document
Document

... The enzyme RNA polymerase opens the DNA strands and synthesizes an RNA complementary to only one of the DNA strands. ...
Molecular Genetics
Molecular Genetics

... Genetics Protein Synthesis ...
Expressing Genetic Information
Expressing Genetic Information

... 2. What is stored in the chromatin, the genetic material of DNA? 3. Genes are discrete units of DNA that act in a certain way. What is that way? 4. Compare and contrast DNA with RNA. 5. What is the genetic code? 6. What is the Human Genome Project? 7. What percentage of RNA is rRNA? Why is it so hig ...
DNA Transcription Translation The Central Dogma Trait RNA
DNA Transcription Translation The Central Dogma Trait RNA

... RNA Is Largely Single-Stranded ...
Nucleus/Nucleolus
Nucleus/Nucleolus

... A barrier between the nucleus and the cytoplasm The place where ribosome subunits assemble Uncoiled DNA that is used in protein synthesis The cell’s control center ...
RNA
RNA

... • Phenotype = physical and chemical state • The phenotype is determined by the proteins synthesised when the genes are expressed ...
LINEs
LINEs

...  3 related LINE families in humans – LINE-1, LINE-2, LINE-3. LINE-1 still active (~17% of human genme)  Believed to be responsible for retrotransposition of SINEs and creation of processed pseudogenes ...
PowerPoint
PowerPoint

... RNA Is Largely Single-Stranded ...
Nuclear genome 1
Nuclear genome 1

... essential for growth (under lab conditions)? • Using transposon mutagenesis, ~150 of the 517 genes could be knocked out; ~ 300 genes deemed essential (under lab conditions), which included: – ~100 of unknown function – Genes for glycolysis & ATP synthesis – ABC transporters – Genes for DNA replicati ...
Document
Document

... • Only about 1.5% of the human genome codes for proteins. (This is also true of many other multicellular eukaryotes.) • Another small fraction of DNA consists of genes for ribosomal RNA and transfer RNA. • A flood of recent data suggests that a significant amount of the remaining genome is transcrib ...
GeneticsLecture3
GeneticsLecture3

... – EST as binf tool for prediction ...
doc Genetics 03-22
doc Genetics 03-22

...  A lot of transposons are inactive –capable of mobility but kept in one place by repressors. Those transposons can be activated under certain conditions – could be advantageous for the organism because it could induce rapid mutation.  They are found in between genes and introns.  They are inconsp ...
What is the most likely path of inheritance?
What is the most likely path of inheritance?

... the possible blood phenotypes for Bernie? Genotypes for all? ...
Control of Gene Expression
Control of Gene Expression

... Post-Translational Control (protein activity) • After translation, various types of protein processing, including cleavage and the addition of chemical groups, are subject to control • Proteasomes are giant protein complexes that bind protein molecules and degrade them • Ubiquitin's are placed on a ...
Student Notes
Student Notes

...  The activity and role of transposable elements and retrotransposons.  How evo-devo relates to our understanding of the evolution of genomes.  The role homeotic genes and homeoboxes How could so many proteins be made with so few genes? Only 1.5% of the human genome codes for proteins or is transc ...
DNA Replication - Texas Tech University
DNA Replication - Texas Tech University

... Gene control regions Control expression of genes ...
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Short interspersed nuclear elements (SINEs)

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