Central dogma: from genome to proteins
... bacterial and eucaryotic RNA polymerases. • .While bacterial RNA polymerase (with s factor as one of its subunits) is able to initiate transcription on a DNA template in vitro without the help of additional proteins, eucaryotic RNA polymerases cannot. They require the help of a large set of proteins ...
... bacterial and eucaryotic RNA polymerases. • .While bacterial RNA polymerase (with s factor as one of its subunits) is able to initiate transcription on a DNA template in vitro without the help of additional proteins, eucaryotic RNA polymerases cannot. They require the help of a large set of proteins ...
Document
... by a DICER enzyme into 21-22 bp fragments. The cut-up RNAs bind to RISC complex as ssRNAs and initiate destruction of all cellular RNAs that share homology to the dsRNA. RNAi has been incredibly useful to researchers because it can be used to reduce the expression of genes that are tough to mutate. ...
... by a DICER enzyme into 21-22 bp fragments. The cut-up RNAs bind to RISC complex as ssRNAs and initiate destruction of all cellular RNAs that share homology to the dsRNA. RNAi has been incredibly useful to researchers because it can be used to reduce the expression of genes that are tough to mutate. ...
BIME, ERIC, REP, RIME, and Other Short Bacterial Repeated
... mosaic combination of REP separated by other sequence elements. BIMEs have been suggested to play a role in transcription termination, mRNA stabilization, control of translation, and genomic rearrangements. These elements also act as binding site for DNA-modifying enzymes such as DNA polymerase, int ...
... mosaic combination of REP separated by other sequence elements. BIMEs have been suggested to play a role in transcription termination, mRNA stabilization, control of translation, and genomic rearrangements. These elements also act as binding site for DNA-modifying enzymes such as DNA polymerase, int ...
Our laboratory studies the regulation of gene expression in
... We have identified histone acetyl transferases and deacetylases that affect gene expression in a position-dependent, promoter-independent (silencing) manner. More recently, we have identified histone methyltransferases that also affect silencing. We are especially interested to know how these and ot ...
... We have identified histone acetyl transferases and deacetylases that affect gene expression in a position-dependent, promoter-independent (silencing) manner. More recently, we have identified histone methyltransferases that also affect silencing. We are especially interested to know how these and ot ...
From Gene to Protein Part 2
... FROM GENE TO PROTEIN PART 2 Goal 1- Understand the process of transcription • How is RNA made? •How ...
... FROM GENE TO PROTEIN PART 2 Goal 1- Understand the process of transcription • How is RNA made? •How ...
Chapter 15
... The prokaryotic promoter has two distinct elements that are not identical. How is this important to the initiation of transcription? (Page 285) Answer: The promoter acts a binding site for RNA polymerase. The structure of the promoter provides information as to both where to bind, but also the direc ...
... The prokaryotic promoter has two distinct elements that are not identical. How is this important to the initiation of transcription? (Page 285) Answer: The promoter acts a binding site for RNA polymerase. The structure of the promoter provides information as to both where to bind, but also the direc ...
REGULATION OF GENE EXPRESSION
... a cluster of genes working together a region of the chromosome near the cluster: operator a region of the chromosome next to the operator: promotor products that initiates the production of enzymes are inducers ...
... a cluster of genes working together a region of the chromosome near the cluster: operator a region of the chromosome next to the operator: promotor products that initiates the production of enzymes are inducers ...
Eukaryotic Gene Expression
... • mRNA present in cytosol does not necessarily get translated into proteins – Control the rate of translation to regulate gene expression ...
... • mRNA present in cytosol does not necessarily get translated into proteins – Control the rate of translation to regulate gene expression ...
5` 3`
... as coding strand (except U instead of T) RNA synthesized in 5’ to 3’ direction with antiparallel DNA strand as template ...
... as coding strand (except U instead of T) RNA synthesized in 5’ to 3’ direction with antiparallel DNA strand as template ...
Exporter la page en pdf
... the movement of tagged chromosomal loci to which transcriptional activators or nucleosome remodeling complexes were targeted. We found that local binding of the transcriptional activator VP16, but not of the Gal4 acidic domain, enhances chromatin mobility. The increase in movement did not correlate ...
... the movement of tagged chromosomal loci to which transcriptional activators or nucleosome remodeling complexes were targeted. We found that local binding of the transcriptional activator VP16, but not of the Gal4 acidic domain, enhances chromatin mobility. The increase in movement did not correlate ...
Genes Section CAN (CAN protein, putative oncogene) Atlas of Genetics and Cytogenetics
... CAN (CAN protein, putative oncogene) Jean-Loup Huret Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France Published in Atlas Database: January 1998 Online version is available at: http://AtlasGeneticsOncology.org/Genes/CAN.html ...
... CAN (CAN protein, putative oncogene) Jean-Loup Huret Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France Published in Atlas Database: January 1998 Online version is available at: http://AtlasGeneticsOncology.org/Genes/CAN.html ...
中文題目：
... wound-response cis-acting elements of sporamin promoter, the genomic walking method was used to clone upstream promoter regions. Three segments of promoter region of this gene family were obtained. Although the sequences of these promoters are various, they all contain almost the same cis-acting ele ...
... wound-response cis-acting elements of sporamin promoter, the genomic walking method was used to clone upstream promoter regions. Three segments of promoter region of this gene family were obtained. Although the sequences of these promoters are various, they all contain almost the same cis-acting ele ...
Interfering with the genome: A new generation of disease treatments
... up new opportunities for the development of radically novel drugs. One exciting area is so-called RNA interference, or RNAi. This new technology involves the creation of drugs that specifically control the expression of genes contributing to a disease state. Genes exist as segments of DNA on chromos ...
... up new opportunities for the development of radically novel drugs. One exciting area is so-called RNA interference, or RNAi. This new technology involves the creation of drugs that specifically control the expression of genes contributing to a disease state. Genes exist as segments of DNA on chromos ...
Protein-coding genes
... whereby base-specific changes are enzymatically introduced at the RNA level. Types of RNA editing in humans: (i) C---> U, occurs in humans by a specific cytosine deaminase e.g. The expression of the human apolipoprotein B gene in the intestine involves tissue-specific RNA editing (ii) A ---> I, the ...
... whereby base-specific changes are enzymatically introduced at the RNA level. Types of RNA editing in humans: (i) C---> U, occurs in humans by a specific cytosine deaminase e.g. The expression of the human apolipoprotein B gene in the intestine involves tissue-specific RNA editing (ii) A ---> I, the ...
Chapter 12.5
... • THE PROMOTER REGION IS WHERE RNA POLYMERASE CAN ATTACH AND START TRANSCRIPTION. • THERE IS ANOTHER REGION CALLED THE OPERATOR. THIS CONTAINS A PROTEINS CALLED A LAC REPRESSOR. IF THE LAC REPRESSOR IS ATTACHED TO THE DNA THE GENE IS TURNED OFF. • THE REPRESSOR WILL BE ON DNA UNLESS LACTOSE IS PRESE ...
... • THE PROMOTER REGION IS WHERE RNA POLYMERASE CAN ATTACH AND START TRANSCRIPTION. • THERE IS ANOTHER REGION CALLED THE OPERATOR. THIS CONTAINS A PROTEINS CALLED A LAC REPRESSOR. IF THE LAC REPRESSOR IS ATTACHED TO THE DNA THE GENE IS TURNED OFF. • THE REPRESSOR WILL BE ON DNA UNLESS LACTOSE IS PRESE ...
Introduction to Genetics and Genomics
... – view is more global due to the development of high-throughput techniques – development of bioinformatics -- (needs the use of computers to manage biological information) -direct consequence of more information available derived from genomics studies. ...
... – view is more global due to the development of high-throughput techniques – development of bioinformatics -- (needs the use of computers to manage biological information) -direct consequence of more information available derived from genomics studies. ...
Brooker Chapter 11
... * often found nearby (-50 to -100) but can also be found great distances away in either direction ...
... * often found nearby (-50 to -100) but can also be found great distances away in either direction ...
Lecture 4-5 Outline
... Differential gene expression: e.g. of 30,000 genes in a typical mammalian cell, only about 5,000 are being transcribed at any time. Which 5000 depends on the cell type. Some are housekeeping genes, all cells transcribe them; some are specific to cell function, such as red blood cells where 95% of pr ...
... Differential gene expression: e.g. of 30,000 genes in a typical mammalian cell, only about 5,000 are being transcribed at any time. Which 5000 depends on the cell type. Some are housekeeping genes, all cells transcribe them; some are specific to cell function, such as red blood cells where 95% of pr ...
Regulation of Gene Activity
... Transcriptional control: transcriptional factors initiate/regulate transcription Posttranscriptional control: mRNA processing and how fast mRNA leaves the nucleus Translational control: when translation begins and how long it continues Posttranslational control: after protein synthesis, polypeptide ...
... Transcriptional control: transcriptional factors initiate/regulate transcription Posttranscriptional control: mRNA processing and how fast mRNA leaves the nucleus Translational control: when translation begins and how long it continues Posttranslational control: after protein synthesis, polypeptide ...
Transcription Control in Eukaryotes - University of Arizona | Ecology
... Example: Activation of GAL Genes in Yeast Tightly linked genes GAL1, GAL7, and GAL10 are coordinately activated or repressed by the activity of two genes on different chromosomes. Their protein products are enzymes required for conversion of galactose to glucose-1-phosphate which enters the glycoly ...
... Example: Activation of GAL Genes in Yeast Tightly linked genes GAL1, GAL7, and GAL10 are coordinately activated or repressed by the activity of two genes on different chromosomes. Their protein products are enzymes required for conversion of galactose to glucose-1-phosphate which enters the glycoly ...
1) Lecture notes: mechanisms of gene activation
... Nutrition and Gene Expression Lecture, part 1, Feb 5, 2015 Overview: Gene Activation ...
... Nutrition and Gene Expression Lecture, part 1, Feb 5, 2015 Overview: Gene Activation ...
Study Guide
... How are the functions of mRNA and tRNA different? Describe the process of transcription and translation. What is a codon? What is an anticodon? How are they related? Why is RNA necessary for expressing the code in DNA? How does an organism’s DNA code for its traits? Summarize the process ...
... How are the functions of mRNA and tRNA different? Describe the process of transcription and translation. What is a codon? What is an anticodon? How are they related? Why is RNA necessary for expressing the code in DNA? How does an organism’s DNA code for its traits? Summarize the process ...
Fish sampling - BioMed Central
... L37 are shown in Table 2. As an indication of tissue distribution of the studied genes, Ct values in the six tissues are shown in Fig. 5. All assays were based on ESTs we have sequenced as part of a largescale Atlantic cod sequencing effort and subsequently uploaded to the Genbank. Gene annotations ...
... L37 are shown in Table 2. As an indication of tissue distribution of the studied genes, Ct values in the six tissues are shown in Fig. 5. All assays were based on ESTs we have sequenced as part of a largescale Atlantic cod sequencing effort and subsequently uploaded to the Genbank. Gene annotations ...