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Human T-Cell Leukemia Virus Type I Induces Adult T
Human T-Cell Leukemia Virus Type I Induces Adult T

... and activated protein 1 (AP-1). Tax does not bind to promoter or enhancer sequences by itself, but it interacts with cellular proteins that are transcriptional factors or modulators of cellular functions. In addition to this transcriptional regulation, it is also known that Tax can functionally inac ...
Danger Theory: The Link between AIS and IDS?
Danger Theory: The Link between AIS and IDS?

fmd with viaa test incl.
fmd with viaa test incl.

... strains. Inactivated equine influenza vaccines contain whole viruses or their subunits. The vaccine viruses are propagated in embryonated hens’ eggs or tissue culture, concentrated, and purified before inactivation with agents such as formalin or beta-propiolactone. Inactivated vaccines provide prot ...
2,6-sialylated Fc
2,6-sialylated Fc

...  Thus, these variants, multiplied by the four different IgG subclasses, result in more than 120 different glycoproteins in the IVIG preparation that could contain the active anti-inflammatory component ...
Adult Immunizations
Adult Immunizations

... • Influenza and pneumococcal vaccines are recommended for patients with COPD. • Influenza vaccine is recommended annually for all adults. High-dose influenza vaccine is an option for patients 65 years and older. ...
Document
Document

... • The MHC-I antigen presentation pathway is most easily thought of as an inside-out pathway by which protein fragments of molecules synthesized by the cell are delivered to and bound by the MHCI molecule during its biosynthesis. • In contrast, the MHC-II antigen presentation pathway is best more cle ...
Immunoinformatics - UWI St. Augustine
Immunoinformatics - UWI St. Augustine

... envelope glycoprotein of Sri Lanka strain of Japanese encephalitis virus. In YiPing Phoebe Chen (ed.), Conferences in research and practice in information ...
DNAse I Qualification and Sample Treatment | Molecular Devices
DNAse I Qualification and Sample Treatment | Molecular Devices

... Assay. If the DNase I digestion fails to reduce the signal produced in the Total DNA Assay by 90% or more, pretreatment methods outlined in the Threshold System Operator's Manual should be investigated. Please note that when analyzing final product samples with less than 10 pg of DNA, it may be diffic ...
RHD - Labex
RHD - Labex

...  Wiener and Landsteiner discovered the Rh factor in 1937/1940  The importance of the Rh factor was the better blood finger print for criminal matters  M, N, or P factors where known and Rh factor was just an additional one  Later it was recognized that the new Rh factor was associated with probl ...
Differential regulation of lipopolysaccharide and Gram
Differential regulation of lipopolysaccharide and Gram

... mediator production. We hypothesized that genetic deletion of Gi proteins would alter cytokine and chemokine production induced by LPS and SA. LPS- and heat killed SA-induced cytokine and chemokine production in splenocytes from wild type (WT), Gαi2 (−/−) or Gαi1/3 (−/−) mice were investigated. LPS- ...
Development of an internally controlled real-time PCR
Development of an internally controlled real-time PCR

... evaluation of the PCR was limited. In the present study, C. psittaci DNA was detected in eight respiratory samples obtained from eight patients (c. 30% (8 ⁄ 27) of the annual reported cases in The Netherlands) [3]. One of these samples had been shown previously to be PCR-positive with a different pr ...
Host-Plasmid Interactions in Saccharomyces
Host-Plasmid Interactions in Saccharomyces

... in proportion with the host cell ploidy, while the copy number of TRp7M was increased in the higher ploidy strains but did not correlate with ploidy. These results suggest that the copy numbers of both the 2pm plasmid and a plasmid derived from it are controlled by a nuclear gene and that, in additi ...
Mutational analysis of protein phosphatase 2C involved in abscisic
Mutational analysis of protein phosphatase 2C involved in abscisic

The rapidly evolving field of plant centromeres
The rapidly evolving field of plant centromeres

... as meiotic drive. Such positive selection could result from a preferential interaction with centromere protein-A (CENP-A), a histone H3 variant that is incorporated into the nucleosomes that specifically bind to centromere DNA in plants, humans, yeast, and Drosophila [28]. If this is the case, even ...
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter

... AG-10 (12). Some of these anastomosis groups are further subdivided based on pathogenicity (AG-1, AG-2), colony morphology (AG-1), thiamine requirement (AG-2, AG-9), and/or DNA homology (AG-4, AG-6) into intraspecific groups (ISG) (11). The ISG is derived by combining anastomosis group affiliation w ...
Mendel and After - U3A Site Builder Home Page
Mendel and After - U3A Site Builder Home Page

... Chemical analysis of chromosomes had shown that they are composed of approximately equal proportions of protein and what is now known as DNA, deoxyribonucleic acid. Both are macromolecules composed of chains of subunits, but which of them carries the hereditary information? ...
Constitutive expression of catABC genes in the aniline
Constitutive expression of catABC genes in the aniline

... a producer of enzymes for the catechol catabolism and a source of their genes. Escherichia coli XL1-Blue (Stratagene) was used as a host for constructing a gene library. A pBluescript II KS+ (Stratagene) was used for the construction of a gene library and subcloning of DNA fragments. Rhodococcus sp. ...
Sequence analysis of T-cell repertoires in health and disease
Sequence analysis of T-cell repertoires in health and disease

Obligate phototrophy in cyanobacteria: more than a lack of sugar
Obligate phototrophy in cyanobacteria: more than a lack of sugar

... acid sequence identity with, and a predictable structure similar to, that of a family of non-phosphorylating sugar carriers largely distributed among prokaryotes and eukaryotes. It thus appeared probable that the carrier of other facultative phototrophic cyanobacteria using glucose as substrate woul ...
Intravenous administration of AAV2/9 to the fetal and
Intravenous administration of AAV2/9 to the fetal and

... vector to the fetal circulation. Fetal gene therapy uniquely offers a number of potential advantages, such as development of immune tolerance to expressed foreign proteins and increased vector-to-cell ratio. The potential of this concept has been reviewed elsewhere ...
On the evolutionary ecology of specific immune defence
On the evolutionary ecology of specific immune defence

... immune action against parasites in animals. We neither intend to review the literature on this subject nor discuss the vast knowledge of molecular and cell biology; our purpose is to clarify the framework for the analysis of specific immune defences within evolutionary ecology. In a nutshell, evolut ...
A human SARS-CoV neutralizing antibody against epitope on S2
A human SARS-CoV neutralizing antibody against epitope on S2

... Abstract An immune antibody phage-display library was constructed from B cells of SARS convalescent patients. More than 80 clones were selected from the library by using the whole inactivated SARS-CoV virions as target. One human scFv, B1, was characterized extensively. The B1 recognized SARS pseudo ...
Contig annotation tool CAT robustly classifies assembled
Contig annotation tool CAT robustly classifies assembled

... We showed that thanks to this feature, CAT outperforms the frequently used best BLAST hit approach, that often misclassifies a sequence due to short, spuriously high scoring hits. Although annotations become less taxonomically resolved, we argue that this is realistically the case in many microbial ...
CD4 § T-Cells from Mice Immunized to
CD4 § T-Cells from Mice Immunized to

... (Sigma, St. Louis, MO), with constant stirring over 2 h at 25~ After nylon mesh filtering and 2 washes in Hanks' balanced salt solution, the resulting single cell suspensions were used either for immunizations or as a source of tumor antigen. Murine Tumor Immunizations. Syngeneic mice were immunized ...
26-17 Dendritic cells - McGraw Hill Higher Education
26-17 Dendritic cells - McGraw Hill Higher Education

... – sequences (epitopes) in long proteins may be antigenic – dendritic cells break down long sequences for presentation to T cells – B cells recognise antigens as sequence of whole protein ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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