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Regulation of Gene Expression
Regulation of Gene Expression

... • In the absence of lactose, the lac repressor protein binds to the operator, preventing RNA polymerase from binding to the promoter to initiate transcription. • In the presence of lactose, an activator binds to the repressor so it can no longer bind to the operator. Transcription of the genes can ...
A chief of endocrinology department, prof. Vlasenko MV
A chief of endocrinology department, prof. Vlasenko MV

... 2. Relevance of topic: The management of patients may be difficult because of problems in achieving of normal glucose control. Because there is good evidence that hyperglycemia conveys risks for all of the common long-term complications of DM, which are the major cases of excess morbidity and mortal ...
Concept Check Questions with answers
Concept Check Questions with answers

... programs that identify overlapping regions. ...
Dr. Palmiter received a AB in Zoology from Duke University in 1964
Dr. Palmiter received a AB in Zoology from Duke University in 1964

... regulate gene transcription. In the 1970's, he and his colleagues showed that sex steroids regulate the transcription of genes responsible for egg white production by laying hens. Later his group turned their attention to the regulation and function of metallothionein genes. These gene products bind ...
Genetics Review Sheet ANSWERS
Genetics Review Sheet ANSWERS

... 10. The tool used to determine the probability of offspring of a cross between two parents is called a ___Punnett Square__________________. 11. What is the phenotypic ratio for a dihybrid cross between two heterozygotes? _3:1____________ 12. During anaphase of meiosis I or meiosis II, the chromosome ...
Viruses as Pathogens in Bacterial Gene Regulation
Viruses as Pathogens in Bacterial Gene Regulation

... – bacteria containing the F-factor (fertility) forms a pili » long extension that pulls another bacteria close » a cytoplasmic bridge is established and DNA is passed from the bacterium with the F factor (F+) to the recipient (F-) – F-factor may be located in a separate circular region called a plas ...
1. Which gene could be X-linked? If it is a male, then only one X
1. Which gene could be X-linked? If it is a male, then only one X

... 1. Which gene could be X-linked? If it is a male, then only one X chromosome would be present and it should segregate into ½ of the sperm cells…Ans: Gene S (c) 2. Which gene could be Y-linked? Exactly the same logic! The Y chromosome would segregrate the same as the X…Ans: Gene S (c) 3. Which gene i ...
Immunology
Immunology

... – says that the genome contains a small number of genes – but from these a large number of antibody specificities are generated – from mutational and recombinational events ...
Answered copy of exam 3
Answered copy of exam 3

... IX. In cattle C_ animals are normal and cc develop cataracts. A DNA based polymorphism detected by PCR is just 4 map units from the cataracts gene. It’s alleles are designated A35 or A50 for the size of the amplified product. Suppose a bull has the genotype ...
Principles of Life
Principles of Life

... • What is the evidence that there was a common ancestor for the developmental pathways leading to segment identity in insects and the organization of the spinal cord in mice? ...
The phenomenon of incomplete The mRNA-counting analysis of penetrance — whereby organisms
The phenomenon of incomplete The mRNA-counting analysis of penetrance — whereby organisms

... with genetically identical alleles can develop distinct phenotypes — has been known for 80 years, and several mechanisms have been proposed to explain it. A paper now provides a quantitative description of the effect of an incompletely penetrant mutation on its gene-network properties. By using a si ...
Transcription and Translation Exercise
Transcription and Translation Exercise

... 7. The allele of the gene above is dominant and codes for red kernel pigment (it is designated as R). Another allele of this gene, the r allele (which is recessive), codes for white kernel pigment and is the result of a mutation in the R allele. In the r allele, the second nucleotide (base) in the s ...
uses_lecturenotes.pdf
uses_lecturenotes.pdf

... • Presymptomatic testing for predicting adult-onset disorders such as Huntington's disease • Presymptomatic testing for estimating the risk of developing adult-onset cancers and Alzheimer's disease • Confirmational diagnosis of a symptomatic individual • Forensic/identity testing 2.) Gene therapy – ...
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... Hemophilia – a Case Study ...
Chromosomes
Chromosomes

... • A single recognition site for the restriction enzyme AluI located near the middle of the Alu element. • Alu elements are found only in primates. • Human chromosomes contain about 1,000,000 Alu copies (10% of the total genome). • Alu is a "jumping gene" – a transposable DNA sequence that "reproduce ...
See Preview - Turner White
See Preview - Turner White

... polymerase and then translated into protein. Introns and untranslated regions are portions of the DNA sequence that are transcribed but not translated. A gene is a portion of the DNA sequence that is the basic unit of inheritance. Genotype is an individual’s genetic makeup; phenotype is an individua ...
Lesson Plan
Lesson Plan

... Opening: Strawberry DNA Extraction Lab, Students view a video describing the process for the lab. Guided Practice: Strawberry DNA Extraction Lab, Students will be given a lab report rubric and the lab report will be due Wednesday/Thursday for a major grade. ...
Red line Introduction
Red line Introduction

... – 19 students used Red Line to visualize next-gen RNA-Seq data to investigate presence/absence variation (PAV) in maize – 12 hours effort, each student group annotated 100 kb and then imported next-gen RNA-Seq data from 5 different tissues in 30 maize inbred lines for a gene that they had previously ...
Wednesday, September 5
Wednesday, September 5

... programs that identify overlapping regions. ...
X-Linked, Epistasis and Multifactorial Problems File
X-Linked, Epistasis and Multifactorial Problems File

... 1. In humans, the gene for color vision is dominant over the gene for colorblindness. This gene is located on the X chromosome. Cross a man who has normal vision with a woman who is colorblind. 2. In humans, the gene for the production of dystrophin (a muscle protein) is dominant to the gene for a l ...
Newdesign2003
Newdesign2003

... ...
The Epigenome WS
The Epigenome WS

... Are there many or few acetyl molecules attached to the genes associated histones? ...
Document
Document

... human gene that causes disease. For example, after the mutation causing cystic fibrosis was identified, the analogous gene was mutated in the mouse. Mice with mutations in this gene have symptoms similar to the human symptoms (though not identical). These mice can be used to study the disease and to ...
Steven Sandoval - Pima Indian Diabetes susceptibility differs significantly from European susceptibility
Steven Sandoval - Pima Indian Diabetes susceptibility differs significantly from European susceptibility

... Diabetes is a complex disease that is not well-understood. Unlike other simpler inheritable diseases, diabetes has consistently been shown to be not linked to any single gene or genetic marker. Current hypotheses are that diabetes is caused by a large number of genes working in tandem to generate th ...
Pita
Pita

... • Map a cloned rice blast resistance gene to its putative location in the rice genome • Compare its position to that of other mapped resistance genes What do we already know ? • The rice disease resistance gene Pi-ta • Genetically mapped to chromosome 12 Rybka et al. (1997). • It has also been seque ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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