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Obstructive sleep apnea syndrome (OSAS) in children with Class III
Obstructive sleep apnea syndrome (OSAS) in children with Class III

... consequently the protein activity. This study is of immense importance as it demonstrates for the first time that naturally occurring silent mutations can lead to the synthesis of a protein product with the same amino acid sequence but different structural and functional properties. In addition, Tom ...
The causes and molecular consequences of polyploidy
The causes and molecular consequences of polyploidy

... gene loss in species that underwent polyploidization events several million years ago (Ma). In the A. thaliana genome, only 17% of duplicates were retained after a paleopolyplodization (␤) event that took place 50 Ma.53 In the paleopolyploid Glycine max, two rounds of whole-genome duplications took ...
embj201490542-sup-0013
embj201490542-sup-0013

... target genes. To define genes that become induced upon Scl expression, SclhCD4 reporter ES cells (Chung et al, 2002) were used to identify genes that become up-regulated in day 4 Scl-expressing mesoderm (Flk1+Scl+) as compared to Flk1+Scl- mesodermal precursors that give rise to other mesodermal lin ...
Nkx5 genes in inner ear development and genome evolution
Nkx5 genes in inner ear development and genome evolution

... Curr. Opin. Neurobiol. 9: 616-21 Harvey, R.P. (1996) NK-2 Homeobox genes and heart development. Dev. Biol. 178: 203-216 Hensey, C., and Gautier, J. (1997) A developmental timer that regulates apoptosis at the onset of gastrulation. Mech. Dev. 69: 183-95 Hebert, J. M., Basilico, C., Goldfarb, M., Hau ...
Polymorphism of the Tumor Necrosis Factor Alpha Gene and Waist
Polymorphism of the Tumor Necrosis Factor Alpha Gene and Waist

... Obesity is increasing in prevalence and is associated with several adverse health problems, including type 2 diabetes, hyperlipidemia, and hypertension. The influence of obesity on the development of obesity-related disorders is complex and probably involves interactions between genetic, nutritional ...
Microsatellite Polymorphism in the Heme Oxygenase
Microsatellite Polymorphism in the Heme Oxygenase

... angioplasty in arterial occlusive diseases (27). They showed that long (GT)n repeats reduced the level of HO-1 induction by oxidative stress in cultured cells and that short (GT)n alleles are likely to provide anti-inflammatory activities of heme breakdown products (26). It is therefore conceivable ...
ENHANCING GENETIC RESISTANCE TO SOYBEAN
ENHANCING GENETIC RESISTANCE TO SOYBEAN

... in seedling and adult plants under screen house and field conditions respectively. When inoculated with the five field isolates, all twelve lines evaluated showed diverse and mixed reactions, suggesting each location differed in soybean rust races and/or virulence. Experimental sites where many dive ...
Rapid Selection of Multiple Gene Integrant for the Production of
Rapid Selection of Multiple Gene Integrant for the Production of

... ber of G418 resistance gene copies in the chromosome. But homologous recombination into MOX locus could not support such multiple integration. The multiple integration of a transforming vector was completely dependent on the function of telomeric ARS used in the vector. Therefore, a vector containin ...
The Role of Oocyte‐Secreted Factors GDF9 and BMP15 in Follicular
The Role of Oocyte‐Secreted Factors GDF9 and BMP15 in Follicular

... and Shimasaki 2002). Unlike GDF9, BMP15 protein is found in the pituitary gland, testis and in several other tissues from many species, suggesting that BMP15 activity is not exclusive to the ovary (Otsuka and Shimasaki 2002). BMP15 mRNA was not detected in oocytes of primordial stage follicles and i ...
Supplementary table I: Yeast strains Used in this study
Supplementary table I: Yeast strains Used in this study

... Supplementary Fig. 2: HXK1 dynamics on glucose versus galactose media. Time-lapse imaging was performed as in Fig. 2 and ref 27, for the lacop tagged HXK1 locus in a wild-type strain (GA-1459) expressing lexA, and grown on glucose or galactose (glucose-free) as indicated. Analysis was performed on t ...
Role of ghrelin and leptin in the regulation of carbohydrate
Role of ghrelin and leptin in the regulation of carbohydrate

... cAMP-dependant protein kinase A (PKA) as well as protein kinase C (PKC). These pathways might play a role in preventing insulin hypersecretion, although they have not been fully explained yet [11,13,43]. Leptin is believed to suppress basal and glucose stimulated insulin release as well as to decrea ...
Basic Heredity
Basic Heredity

... • Mendel used pea plants to examine heredity from one generation to the next ...
Supplementary Figure Legends - Word file
Supplementary Figure Legends - Word file

... transcription site (purple). Three theoretical positions of the episomes in 3D7/upsC are shown (1-3). Postion 1 (transcriptionally inactive zone) does not occur since parasites would be unable to survive blasticidin-S treatment. The silenced episome assumes position 2 (transcriptionally active regio ...
Impact of nucleosome dynamics and histone modifications
Impact of nucleosome dynamics and histone modifications

... The genetic material in eukaryotes is permanently associated with structural proteins (histone and nonhistone proteins) in a high-order and highly compact macromolecular structure called chromatin. The nucleosome is a basic repeating unit of chromatin that consists of B150 base pairs of DNA wrapped ...
Dual-Tagging Gene Trap of Novel Genes in Drosophila
Dual-Tagging Gene Trap of Novel Genes in Drosophila

... cDNA. The total recombinant ␭-phage DNAs prepared from each of several cDNA libraries are used as templates for PCR analysis. In the first round, four parallel PCRs are run with the primer corresponding to one strand of the expressed sequence, paired with either the forward primer or reverse primer ...
2557-9370-1-RV
2557-9370-1-RV

... Address: Hexing Road No. 26, Xiangfang District, Harbin City, Heilongjiang Province 150040, China Tel: (86)-0451-82191394 Fax: (86)-0451-82191394 ...
Liz`s PowerPoint presentation
Liz`s PowerPoint presentation

...  Genes make proteins that do special jobs in the body  If a gene has a bit missing or the sequence of letters is wrong…  The protein might not get made or will be faulty and not do its job ...
Topic guide 7.5: Patterns of inheritance
Topic guide 7.5: Patterns of inheritance

... hormone testosterone. Males of genotype BB or Bb will become bald, whereas females of Bb will not be bald, but those of genotype BB will develop baldness. The B allele is not a common mutation, so there are few females with pattern baldness. Even when they have the genotype BB their baldness is less ...
Exercises Biological databases PART
Exercises Biological databases PART

... Bioinformatics (updated 2015 january) ...
The surface-located YopN protein is involved in calcium signal
The surface-located YopN protein is involved in calcium signal

... Mw ...
supplement 3 - Springer Static Content Server
supplement 3 - Springer Static Content Server

... simulation dataset, a covariance matrix COV(X)=[5.94 2.14 2.15; 2.14 5.94 2.13; 2.15 2.13 5.94] was obtained. The three eigenvalues ( 1 , 2 , 3 ) and their corresponding eigenvectors ( e1 , e2 , e3 ) were also calculated from the above covariance matrix. ...
PDF
PDF

... marsupials and eutherians. These genes encode proteins that are homologous to a retrotransposon Gag capsid protein and sometimes also have a Pol-like region. We previously demonstrated that PEG10 (SIRH1) and PEG11/RTL1 (SIRH2) play essential but different roles in placental development. PEG10 is con ...
Chapter 7
Chapter 7

... DNA Methylation • DNA methylation, the addition of methyl groups to certain bases in DNA, is associated with reduced transcription in some species • DNA methylation can cause long-term inactivation of genes in cellular differentiation • In genomic imprinting, methylation regulates expression of eit ...
On the bursting of gene products
On the bursting of gene products

... Understanding the origin of fluctuations at the single cell level and how organisms deal them to guarantee both developmental viability and evolutionary adaptation to a constantly changing environment conditions is a challenge of the post-genomic era [3, 4]. Often, stochasticity at the single cell ...
length of exons and introns in genes of some human chromosomes
length of exons and introns in genes of some human chromosomes

... including 1 to 11 genes per region of chromosome 1 (average value was 4 genes/Mbp) exon length decreased from 282 to 135 nt, as well as the number of introns in genes (Nin) increased. The average total exon lengths (Lex) in genes increased from 691 to 3163 nt and the positive correlation between Nin ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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