open access - Max-Planck-Institut für Pflanzenzüchtungsforschung
... during domestication, genome-wide comparison of expression between domesticated and multiple wild species is lacking. One of the most heavily studied domestication events is that of tomato. Tomato is a member of a complex of 13 interfertile species that occupy a wide range of habitats in South Amer ...
... during domestication, genome-wide comparison of expression between domesticated and multiple wild species is lacking. One of the most heavily studied domestication events is that of tomato. Tomato is a member of a complex of 13 interfertile species that occupy a wide range of habitats in South Amer ...
Immunome database for marsupials and monotremes Open Access
... Genome sequencing has generated huge amounts of genomic data. This has expedited the identification of genes in these species. Despite the availability of genome assemblies, only the most phylogenetically conserved immune genes have been identified using automated gene annotation pipelines. Genes in ...
... Genome sequencing has generated huge amounts of genomic data. This has expedited the identification of genes in these species. Despite the availability of genome assemblies, only the most phylogenetically conserved immune genes have been identified using automated gene annotation pipelines. Genes in ...
Gene Section PHOX2B (paired-like homeobox 2b) Atlas of Genetics and Cytogenetics
... Localization of mutations within the PHOX2B gene. In the figure some PARMS (yellow) and NPARMS (black) PHOX2B mutations are shown (see also Weese-Mayer et al., 2010). ...
... Localization of mutations within the PHOX2B gene. In the figure some PARMS (yellow) and NPARMS (black) PHOX2B mutations are shown (see also Weese-Mayer et al., 2010). ...
Warren, ST and Nelson, DL: Trinucleotide repeat expansions in neurological disease. Current Opinion in Neurobiology 3:752-759 (1993).
... organisms. One such mechanism is trinucleotide repeat expansions [ l*,2,3*]. Since early 1991, when the mutation responsible for the fragile X syndrome was uncovered as an astounding expansion of an exonic CGG-repeat, four other human genetic diseases have been similarly demonstrated to be due to su ...
... organisms. One such mechanism is trinucleotide repeat expansions [ l*,2,3*]. Since early 1991, when the mutation responsible for the fragile X syndrome was uncovered as an astounding expansion of an exonic CGG-repeat, four other human genetic diseases have been similarly demonstrated to be due to su ...
Using Bayesian Networks to Analyze Expression Data - CS
... In this paper, we introduce a new approach for analyzing gene expression patterns, that uncovers properties of the transcriptional program by examining statistical properties of dependence and conditional independence in the data. We base our approach on the well-studied statistical tool of Bayesian ...
... In this paper, we introduce a new approach for analyzing gene expression patterns, that uncovers properties of the transcriptional program by examining statistical properties of dependence and conditional independence in the data. We base our approach on the well-studied statistical tool of Bayesian ...
Appendix_1_SimpleNomenclature(plain)
... Sometimes what you want to do is a little rough work for investigating your genetic model. A genetic model is a diagram of the logic that you propose for inheritance. For instance, if you cross a true-breeding purple plant with a true-breeding white plant (e.g. see Figure 2 on page 2; cross the oute ...
... Sometimes what you want to do is a little rough work for investigating your genetic model. A genetic model is a diagram of the logic that you propose for inheritance. For instance, if you cross a true-breeding purple plant with a true-breeding white plant (e.g. see Figure 2 on page 2; cross the oute ...
Genomewide Association Studies and Assessment of the Risk of
... (CFH) gene, are common in the populations studied (allele frequencies of 36% and 57% among unaffected persons), and the other three variants have allele frequencies of 5 to 19% in the populations studied.23 Taken together, these five variants more than double the risk of age-related macular degenera ...
... (CFH) gene, are common in the populations studied (allele frequencies of 36% and 57% among unaffected persons), and the other three variants have allele frequencies of 5 to 19% in the populations studied.23 Taken together, these five variants more than double the risk of age-related macular degenera ...
Functional analyses of genetic pathways controlling
... MADS-box genes are crucial regulators of floral development, yet how their functions have evolved to control different aspects of floral patterning is unclear. To understand the extent to which MADS-box gene functions are conserved or have diversified in different angiosperm lineages, we have exploi ...
... MADS-box genes are crucial regulators of floral development, yet how their functions have evolved to control different aspects of floral patterning is unclear. To understand the extent to which MADS-box gene functions are conserved or have diversified in different angiosperm lineages, we have exploi ...
Y genetic variation and phenotypic diversity in health and disease
... identified ChrY as a contributor to hypertension in males. A rat model was used to investigate the genetic mechanism driving spontaneous hypertension in SHR (S) rats compared to the normotensive Wistar-Kyoto (W) rat [39]. Male offspring from the W × S cross have higher blood pressure than males from ...
... identified ChrY as a contributor to hypertension in males. A rat model was used to investigate the genetic mechanism driving spontaneous hypertension in SHR (S) rats compared to the normotensive Wistar-Kyoto (W) rat [39]. Male offspring from the W × S cross have higher blood pressure than males from ...
Specialized techniques for site-directed mutagenesis in cyanobacteria
... general should not replicate in cyanobacteria) should have the sequences necessary for replication in the E. coli strain used for conjugation, selectable markers for selection in the two hosts of interest, cloning sites, and a mobilizable replicon (e.g., pBR322, which carries a bom [basis of mobilit ...
... general should not replicate in cyanobacteria) should have the sequences necessary for replication in the E. coli strain used for conjugation, selectable markers for selection in the two hosts of interest, cloning sites, and a mobilizable replicon (e.g., pBR322, which carries a bom [basis of mobilit ...
JUNGLE IGUANA ( Green ) well adapted to heavy tropical forest
... • 1. Your Conclusion: Based on your observations…what causes long and short wings in fruit Flies? ( worth 0 points ) • 2. Give all evidence you can to support your ...
... • 1. Your Conclusion: Based on your observations…what causes long and short wings in fruit Flies? ( worth 0 points ) • 2. Give all evidence you can to support your ...
word
... Epigenetic regulation of the X chromosome in C. elegans The X chromosome has no partner during XO male meiosis in C. elegans, and as such is targeted for repression by meiotic silencing mechanisms recognizing unsynapsed/unpaired chromatin. The near-complete paucity of germlineexpressed genes on the ...
... Epigenetic regulation of the X chromosome in C. elegans The X chromosome has no partner during XO male meiosis in C. elegans, and as such is targeted for repression by meiotic silencing mechanisms recognizing unsynapsed/unpaired chromatin. The near-complete paucity of germlineexpressed genes on the ...
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... During the past several years, searching susceptibility loci for various human diseases has been revolutionized by genome-wide association studies (GWAS). Although a significant number of single-nucleotide polymorphism (SNP) have been reported to be associated with various human complex traits [1], ...
... During the past several years, searching susceptibility loci for various human diseases has been revolutionized by genome-wide association studies (GWAS). Although a significant number of single-nucleotide polymorphism (SNP) have been reported to be associated with various human complex traits [1], ...
fontanes et al.indd - RiuNet
... colours influenced by the agouti and extension mutations. This allele dilutes the black to blue (grey) and the yellow to beige coat colours of several rabbit breeds and lines (Castle, 1930; Robinson, 1958; Searle, 1968; Fox 1994). In other species, similar effects on coat colour are determined by mu ...
... colours influenced by the agouti and extension mutations. This allele dilutes the black to blue (grey) and the yellow to beige coat colours of several rabbit breeds and lines (Castle, 1930; Robinson, 1958; Searle, 1968; Fox 1994). In other species, similar effects on coat colour are determined by mu ...
Document
... The inheritance of physical traits by biological organisms is a fascinating phenomenon. Every human inherits specific genes from their parents. These genes play a crucial role in determining many of our physical traits, from the color of our eyes and length of our nose, to different kinds of disease ...
... The inheritance of physical traits by biological organisms is a fascinating phenomenon. Every human inherits specific genes from their parents. These genes play a crucial role in determining many of our physical traits, from the color of our eyes and length of our nose, to different kinds of disease ...
Disease Genomics Part 2 - Medical Sciences Division
... (1) a given positional candidate is queried for high-scoring interaction partners (“virtual pull-down”). These are interaction partners for the candidate complex. (2) proteins known to be involved in disease are identified in the candidate complex, and pairwise scores of the phenotypic overlap betw ...
... (1) a given positional candidate is queried for high-scoring interaction partners (“virtual pull-down”). These are interaction partners for the candidate complex. (2) proteins known to be involved in disease are identified in the candidate complex, and pairwise scores of the phenotypic overlap betw ...
Application of Microarrays to the Analysis of Gene Expression in Cancer
... widely used in microarray experiments when cell lines or patient samples are selected and profiled. Most of the “profiling papers” have used this design, which offers the ability to use data from many different individuals but offers no intrinsic control for bias in the patient populations or cell p ...
... widely used in microarray experiments when cell lines or patient samples are selected and profiled. Most of the “profiling papers” have used this design, which offers the ability to use data from many different individuals but offers no intrinsic control for bias in the patient populations or cell p ...
Involvement of HLS1 in Sugar and Auxin
... (data not shown). Fig. 2 shows that the levels of hls1-1 and hls1-7 transcripts were higher than that of the wild type, suggesting that HLS1 is subject to negative feedback regulation. A decrease in HLS1/hls1 transcripts by the presence of Suc was observed only in hls1 mutants, indicating that HLS1 ...
... (data not shown). Fig. 2 shows that the levels of hls1-1 and hls1-7 transcripts were higher than that of the wild type, suggesting that HLS1 is subject to negative feedback regulation. A decrease in HLS1/hls1 transcripts by the presence of Suc was observed only in hls1 mutants, indicating that HLS1 ...
Genome-scale profiling of histone H3.3 replacement patterns
... RNA polymerase II (Pol II; using an antibody to the C-terminal domain) had patterns that corresponded closely with those of H3.3 (Fig. 2e,f). We also observed this similarity between H3.3 and markers of active chromatin and transcription for other gene-rich regions. Therefore, replication-independen ...
... RNA polymerase II (Pol II; using an antibody to the C-terminal domain) had patterns that corresponded closely with those of H3.3 (Fig. 2e,f). We also observed this similarity between H3.3 and markers of active chromatin and transcription for other gene-rich regions. Therefore, replication-independen ...
Simplified global gene expression profiling
... detailing the read counts per gene in a tab-delimited text file. When setting up a sequencing run, the mapping reference and the AmpliSeqRNA plug-in may be configured in the run plan such that all data are automatically mapped and analyzed once the raw sequencing data have been collected. The number ...
... detailing the read counts per gene in a tab-delimited text file. When setting up a sequencing run, the mapping reference and the AmpliSeqRNA plug-in may be configured in the run plan such that all data are automatically mapped and analyzed once the raw sequencing data have been collected. The number ...
Causes, Risks, Prevention
... What Causes Pancreatic Cancer? Scientists don’t know exactly what causes most pancreatic cancers, but they have found several risk factors that can make a person more likely to get this disease. Some of these risk factors affect the DNA of cells in the pancreas, which can result in abnormal cell gro ...
... What Causes Pancreatic Cancer? Scientists don’t know exactly what causes most pancreatic cancers, but they have found several risk factors that can make a person more likely to get this disease. Some of these risk factors affect the DNA of cells in the pancreas, which can result in abnormal cell gro ...
The making of the Fittest: Natural Selection and
... regulatory switches that allow for transcription of that gene in multiple tissues. The expression of Pitx1 is important in various tissues because the Pitx1 protein is itself a regulatory protein that serves many roles in the development of the fish. Pitx1 controls the expression of multiple genes, ...
... regulatory switches that allow for transcription of that gene in multiple tissues. The expression of Pitx1 is important in various tissues because the Pitx1 protein is itself a regulatory protein that serves many roles in the development of the fish. Pitx1 controls the expression of multiple genes, ...
Leukaemia Section t(3;8)(q26;q24) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
... © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Functional Genomics I: Transcriptomics and
... Find genes that are essential in procyclics but not in blood form T. brucei. Note: for this exercise use http://TriTrypDB.org. ...
... Find genes that are essential in procyclics but not in blood form T. brucei. Note: for this exercise use http://TriTrypDB.org. ...
Chromatin dynamics during cellular differentiation in the female
... imply cellular reprogramming operating at the physiological, cytological and transcriptome level, but also at the chromatin level. A number of observations point to large-scale chromatin reorganization events associated with cellular differentiation of the female spore mother cells and of the female ...
... imply cellular reprogramming operating at the physiological, cytological and transcriptome level, but also at the chromatin level. A number of observations point to large-scale chromatin reorganization events associated with cellular differentiation of the female spore mother cells and of the female ...