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Regulatory genes
Regulatory genes

... Regulatory genes regulate the expression of ot her genes. For example, a regulatory gene may ‘silence’ another gene from expressing its dominant trait. The Manx cat has no tail because it has a r egulatory gene that silences the gene that e xpresses the tail. This tail silencing gene is d ominant an ...
Antibiotic Resistance Markers in Genetically Modified (GM) Crops
Antibiotic Resistance Markers in Genetically Modified (GM) Crops

... that there were no significant food, feed or environmental concerns about the commercial release of this product. The French government approved the cultivation of the product under the condition of monitoring for increased insect-resistance and potential transfer of the ampicillin resistance gene t ...
AllBio_DJK
AllBio_DJK

... • Most significant gene from eQTL study • Mitochondrial gene • Function of this particular gene not clear. • “Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the ...
A novel NUP98/RARG gene fusion in acute myeloid
A novel NUP98/RARG gene fusion in acute myeloid

... abbreviations for Figure 2, “DBD, DNA-binding domain and distribution and arrows the joining site” has been rephrased as “DBD, DNA-binding domain. Arrows indicate the joining sites.” Please confirm or correct. DNA-binding domain. Arrows indicate the joining sites. ...
Results
Results

... seven different results. For the unsupervised part, there are four methods including Principal component analysis (PCA), Laplacian score, variance and Spectral feature selection. The last three methods prioritize the importance of each dimension, but PCA is slightly different from that, it merges or ...
Lec 11 - Development of e
Lec 11 - Development of e

... genes are found in tumor producing viruses such as φ X 174, SV 40 and G4, in virus φ X 174 gene A overlaps gene B. In virus SV 40, the same nucleotide sequence codes for the protein VP 3 and also for the coboxyl – terminal end of the protein VP2. In virus G4, the gene A overlaps gene B and gene E ov ...
Gene expression
Gene expression

... extensive data mining is required to identify the patterns that characterize the underlying mechanisms of action. For biologists, a key aim when analyzing microarray data is to group genes based on the temporal patterns of their expression levels Provides insights into genetic capacities and their i ...
Gene Section SHBG (sex hormone binding globulin) -
Gene Section SHBG (sex hormone binding globulin) -

... estradiol that is known to be a critical factor in breast cancer. In a case-controlled study within the European Prospective Investigation into Cancer and Nutrition (EPIC), SHBG levels in postmenopausal women who developed breast cancer were confirmed to be significantly lower compared with controls ...
Identifying Factors that Control Mechanoreceptor Neuron
Identifying Factors that Control Mechanoreceptor Neuron

... with FLP abnormalities appeared to be true-breeding mutants, the only true-breeding mutant identified exhibits interesting TRN abnormalities. While finding a TRN or FLP morphological mutant was a secondary goal of the project (the primary goal was to find expression mutants), the mutant nonetheless ...
PPT - Bioinformatics.ca
PPT - Bioinformatics.ca

... • My cool new screen worked and produced 1000 hits! …Now what? • Genome-Scale Analysis (Omics) – Genomics, Proteomics ...
srep09383-s1
srep09383-s1

... cluster specific capture vectors were also generated on pCAPB1 and pCAPB2 with four pairs of primers srf1-Up/Down-F/R and srf2-Up/Down-F/R, respectively. In prior to direct TAR cloning, the pathway specific capture vectors were digested with an appropriate restriction enzyme that cuts junction regio ...
Praktikum der Microarray-Datenanalyse
Praktikum der Microarray-Datenanalyse

... • if H0 is true, no more than a fraction α of the replications will yield a p-value ≤ α • subject-sampling p-value: replications involve taking a new sample of subjects and measure same genes → a significant p-values gives confidence to find the same associations within a new sample of subjects • ge ...
Lab 9: Regulation of lactose metabolism
Lab 9: Regulation of lactose metabolism

... substrate, lactose. There is also a positive control system operating in the lac operon. Maximal induction of the lac operon also requires the CAP- cAMP (catabolite activator protein complexed with cyclic adenosine monophosphate) complex that binds to the DNA at the CRP recognition site at the begin ...
Regulatory Network Control of Blood Stem Cells
Regulatory Network Control of Blood Stem Cells

... be affected by ablation of the factor in question. This has raised the issue of a need to distinguish “functionally significant” from “non-significant” binding events 35. However, there are no consensus definitions for these terms, thus leaving the community with no reliable strategy to predict whet ...
GEDI Input Data Format - Boston Children`s Hospital
GEDI Input Data Format - Boston Children`s Hospital

... For dynamic analysis, the data matrix contains J header rows on the top, one for each class of sample Sj . Thus, in our example there will be three header rows for the 3 time series. Each Header Row contains the sample labels of a class Si. The first column in each header rows contains the name of t ...
Supporting Online Material
Supporting Online Material

... Figure S9. Scheme of crossing for silencing of dUTPase in the dorsal compartment of Drosophila wing imaginal discs. Crossing scheme is shown on panel (A): virgin females of the MS1096 Gal4 enhancer trap line expressing Gal4 preferentially in the dorsal compartment of the wing and carrying UAS-Dicer2 ...
Shastry, B.S. 2002. SNP alleles in human disease and evolution
Shastry, B.S. 2002. SNP alleles in human disease and evolution

... level because of their frequent occurrence throughout the genome, and they can be useful in association studies. However, they are less informative, in the sense that humans have relatively low nucleotide diversity compared with Drosophila and maize, than another type of marker called a microsatelli ...
Themes in Biology
Themes in Biology

... human tissues, the immune system is designed to attack the invader.  The risk of stimulating the immune system in a way that reduces gene therapy effectiveness is always a potential risk.  Furthermore, the immune system's enhanced response to invaders makes it difficult for gene therapy to be repe ...
Enolase and Glycolytic Flux Play a Role in the Regulation
Enolase and Glycolytic Flux Play a Role in the Regulation

... glucose medium: it exhibits a 4.5-fold increase of doubling time as compared to wild-type cells (450 min vs. 110 min; data not shown). Better growth of mutant cells on complete medium is probably supported by other carbon sources (e.g., amino acids) in this medium. Enolase activity of Kleno mutant a ...
Glycosylphosphatidyl inositol-anchored protein (GPI
Glycosylphosphatidyl inositol-anchored protein (GPI

... cross-linking of GPI-80 induced up-regulation of CD11b/CD18 expression on neutrophil surfaces and shedding of L-selectin.26) Because an inhibitor of PI-3 kinase blocks GPI-80-mediated tyrosine phosphorylation of pp34, PI-3 kinase may be important for the activation of Src protein tyrosine kinases (P ...
PPT - Blumberg Lab
PPT - Blumberg Lab

... – can target recombination to specific tissues and times – can study genes that are embryonic lethal when disrupted – can use for marker eviction – can study the role of a single gene in many different tissues with a single mouse line – can use for engineering translocations and inversions on chromo ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... interacts with the promoters of active genes, and the NPC-associated protein Mlp1 (myosin-like protein 1) accumulates at the 3′ end of active genes, where it contributes to an RNA surveillance mechanism. Optimal activation can require both localization of the induced gene at the NPC as well as at th ...
upstream sequence of a differentiation
upstream sequence of a differentiation

... 1986, 1989). Several other cultured rabbit cell types including esophageal epithelial cells, kidney epithelial cells, mesothelial cells and fibroblasts do not synthesize K3. Therefore a panel of cultured cells, all of the same rabbit origin, is available, and is ideally suited for studying the tissu ...
FOXP2 in focus: what can genes tell us about speech and language?
FOXP2 in focus: what can genes tell us about speech and language?

... of the problems in this family appears to be very straightforward, consistent with the involvement of just Box 1. FOXP2 hunting Even when family and twin-based data strongly suggest that genes play a role in a particular cognitive or behavioural trait, finding the particular gene or genes involved i ...
Novel visual system homeobox 1 gene mutations in Turkish patients
Novel visual system homeobox 1 gene mutations in Turkish patients

... 0.964/probably damaging 0.986/probably damaging ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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