Leukaemia Section t(3;7)(q26;q21) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... in AML with t(3;12) translocation. EVI1 is also involved in other translocations such as t(2;3)(p13;q26), t(2;3)(q23;q26), t(3;17)(q26;q22) and t(3;13)(q26;q13-14). Other studies have reported abnormal expression of EVI1 in MDS and AML without 3q26 structural abnormalities, suggesting that inappropr ...
... in AML with t(3;12) translocation. EVI1 is also involved in other translocations such as t(2;3)(p13;q26), t(2;3)(q23;q26), t(3;17)(q26;q22) and t(3;13)(q26;q13-14). Other studies have reported abnormal expression of EVI1 in MDS and AML without 3q26 structural abnormalities, suggesting that inappropr ...
RTPrimerDB: the real-time PCR primer and probe database, major
... annotation data and links to Entrez Gene and Ensembl, followed by a graphical representation of the aligned primer and probe sequences onto the different transcript variants available from Ensembl. The occurrence of SNPs in the region where the primer/probe anneals and the exact location of the ampl ...
... annotation data and links to Entrez Gene and Ensembl, followed by a graphical representation of the aligned primer and probe sequences onto the different transcript variants available from Ensembl. The occurrence of SNPs in the region where the primer/probe anneals and the exact location of the ampl ...
PTPL1 as a breast cancer prognostic marker - HAL
... LAR ectopic expression on the growth of neu-transformed human breast carcinoma cells (15) implies a negative role of LAR on the growth or survival of breast cancer cells. On the other hand, Yang et al. (16) showed increased expression of a LAR isoform in malignant breast tissues. This LAR isoform, g ...
... LAR ectopic expression on the growth of neu-transformed human breast carcinoma cells (15) implies a negative role of LAR on the growth or survival of breast cancer cells. On the other hand, Yang et al. (16) showed increased expression of a LAR isoform in malignant breast tissues. This LAR isoform, g ...
Study of lipid metabolism-related genes as candidate
... amount of body fat. Nellore heifers that are heavier at 12 and 18 months go into first heat at a younger age (Alencar et al., 1987). Recent studies in humans have shown that girls with a relatively higher body mass index are more likely to menstruate early (Kaplowitz, 2008; Wagner et al., 2012). In ...
... amount of body fat. Nellore heifers that are heavier at 12 and 18 months go into first heat at a younger age (Alencar et al., 1987). Recent studies in humans have shown that girls with a relatively higher body mass index are more likely to menstruate early (Kaplowitz, 2008; Wagner et al., 2012). In ...
In recent year there have been rapid progress made in mapping the
... In analyzing microarray data it is often necessary to detect genes that are differentially expressed between two or more samples. This project aims to apply two methods to address statistical issues that arise when identifying differentially expressed genes. The first is a geneby-gene analysis that ...
... In analyzing microarray data it is often necessary to detect genes that are differentially expressed between two or more samples. This project aims to apply two methods to address statistical issues that arise when identifying differentially expressed genes. The first is a geneby-gene analysis that ...
Extensive post-transcriptional regulation of miRNAs within
... biological functions including cell proliferation, apoptosis and differentiation. Consequently it is not surprising that disruption of miRNA synthesis plays an important role in various human diseases including cancer. The biogenesis of miRNAs lends itself to regulation at several stages, from trans ...
... biological functions including cell proliferation, apoptosis and differentiation. Consequently it is not surprising that disruption of miRNA synthesis plays an important role in various human diseases including cancer. The biogenesis of miRNAs lends itself to regulation at several stages, from trans ...
Interplay between the transcription factors acting on
... expression of the genes that form the UGA regulon is inducible by GABA and sensitive to nitrogen catabolite repression (NCR). GABA induction of these genes is mediated by Uga3 and Dal81 transcription factors, whereas GATA factors are responsible for NCR. Here, we show how members of the UGA regulon ...
... expression of the genes that form the UGA regulon is inducible by GABA and sensitive to nitrogen catabolite repression (NCR). GABA induction of these genes is mediated by Uga3 and Dal81 transcription factors, whereas GATA factors are responsible for NCR. Here, we show how members of the UGA regulon ...
Gene Gorging Mutagenesis for the Geobacteraceae
... Gene gorging is one way to make a strain with multiple mutations without having to insert a different antibiotic resistance marker into each mutant allele. For gene deletions, Cre-lox mutagenesis also works in G. sulfurreducens, and has the advantage of antibiotic selection at every step Gene gorgin ...
... Gene gorging is one way to make a strain with multiple mutations without having to insert a different antibiotic resistance marker into each mutant allele. For gene deletions, Cre-lox mutagenesis also works in G. sulfurreducens, and has the advantage of antibiotic selection at every step Gene gorgin ...
Seed specific polycomb group gene and methods of use for same
... mals. Further, due to the highly conserved nature of this family of genes, particularly in the SET domain, and in the CXC domain it is expected that other such genes may be identi?ed using the DNA and amino acid sequences herein to characteriZe other closely related genes from other spe cies. As use ...
... mals. Further, due to the highly conserved nature of this family of genes, particularly in the SET domain, and in the CXC domain it is expected that other such genes may be identi?ed using the DNA and amino acid sequences herein to characteriZe other closely related genes from other spe cies. As use ...
19.1 CONSTITUTIVE, INDUCIBLE AND REPRESSIBLE GENE
... synthesized by plants as β-D-galactoside derivatives. There is circumstantial evidence that glycosidases in general (and β-D-galactosidases in particular) made by fecal bacteria (including E. coli) contribute to colon and rectal cancer. For more on this provocative notion see Tamura, G. et al (1980) ...
... synthesized by plants as β-D-galactoside derivatives. There is circumstantial evidence that glycosidases in general (and β-D-galactosidases in particular) made by fecal bacteria (including E. coli) contribute to colon and rectal cancer. For more on this provocative notion see Tamura, G. et al (1980) ...
Convergent evolution of antifreeze glycoproteins in
... AFGP genes are transcribed and translated into large polyproteins that are posttranslationally cleaved. The near-identical AFGP protein structures from the two fishes have led to suggestions of a common ancestor (18), and the apparent similarities in their AFGP genes appear to support such an argume ...
... AFGP genes are transcribed and translated into large polyproteins that are posttranslationally cleaved. The near-identical AFGP protein structures from the two fishes have led to suggestions of a common ancestor (18), and the apparent similarities in their AFGP genes appear to support such an argume ...
History of Biotech and Biotech Applications
... soft, spongy bread rather than a firm, thin cracker, they were acting as fledgling biotechnologists. The first animal breeders, realizing that different physical traits could be either magnified or lost by mating appropriate pairs of animals, engaged in the manipulations of biotechnology. ...
... soft, spongy bread rather than a firm, thin cracker, they were acting as fledgling biotechnologists. The first animal breeders, realizing that different physical traits could be either magnified or lost by mating appropriate pairs of animals, engaged in the manipulations of biotechnology. ...
File
... soft, spongy bread rather than a firm, thin cracker, they were acting as fledgling biotechnologists. The first animal breeders, realizing that different physical traits could be either magnified or lost by mating appropriate pairs of animals, engaged in the manipulations of biotechnology. ...
... soft, spongy bread rather than a firm, thin cracker, they were acting as fledgling biotechnologists. The first animal breeders, realizing that different physical traits could be either magnified or lost by mating appropriate pairs of animals, engaged in the manipulations of biotechnology. ...
ika1 and rag1 as Markers for the Development of
... cent protein (GFP) gene. These reporter constructs will then be used to create two lines of transgenic fish. These fish could be quickly and easily screened for expected expression of the transgenes simply by looking at them under a FITC light filter, a method which will hopefully be not only quicke ...
... cent protein (GFP) gene. These reporter constructs will then be used to create two lines of transgenic fish. These fish could be quickly and easily screened for expected expression of the transgenes simply by looking at them under a FITC light filter, a method which will hopefully be not only quicke ...
proposal
... mutations affecting the Arginine at position 482 (R482Q, R482W, R482L). 90% of the FPLD-associated LMNA patients and 12% of all laminopathy patients have a mutation in this highly conserved arginine [28, 31]. Nearby there are two more mutations changing the Lysine at position 486 (K486N, K486T) [32] ...
... mutations affecting the Arginine at position 482 (R482Q, R482W, R482L). 90% of the FPLD-associated LMNA patients and 12% of all laminopathy patients have a mutation in this highly conserved arginine [28, 31]. Nearby there are two more mutations changing the Lysine at position 486 (K486N, K486T) [32] ...
Gene Section RASSF6 (Ras association (RalGDS/AF-6) domain family member 6)
... The release of RASSF6 was shown to be WW45dependent since RASSF6 remained in complex with MST2 following OA treatment of cells in which WW45 had been depleted by RNAi. Furthermore, the release of RASSF6 appears to be necessary for RASSF6-mediated apoptosis. However, apoptosis was vastly reduced in c ...
... The release of RASSF6 was shown to be WW45dependent since RASSF6 remained in complex with MST2 following OA treatment of cells in which WW45 had been depleted by RNAi. Furthermore, the release of RASSF6 appears to be necessary for RASSF6-mediated apoptosis. However, apoptosis was vastly reduced in c ...
Recombinant Paper Plasmids Cut-and
... yielding “sticky ends,” single strands of nucleotide bases capable of binding with complementary sticky ends. By using enzymes that will cut the DNA on either side of the gene, the gene can be clipped out of the DNA strand. Once scientists obtain the gene they are looking for, they must somehow get ...
... yielding “sticky ends,” single strands of nucleotide bases capable of binding with complementary sticky ends. By using enzymes that will cut the DNA on either side of the gene, the gene can be clipped out of the DNA strand. Once scientists obtain the gene they are looking for, they must somehow get ...
function Complex genomic rearrangements lead to novel primate gene
... than within the human paralogs should reveal divergent paralogs in terms of rearrangements in the gene structure. Thus, depending on this score, we defined two categories for the classification of the observed duplications. When the pairwise alignment score is higher within the human paralogs, it is ...
... than within the human paralogs should reveal divergent paralogs in terms of rearrangements in the gene structure. Thus, depending on this score, we defined two categories for the classification of the observed duplications. When the pairwise alignment score is higher within the human paralogs, it is ...
PDF
... metabolic profile of young children and adolescents of Greek origin. DESIGN: One hundred and fifty-three overweight and obese Greek children (mean age 11.08±2.23 years) and 151 age-matched normal-weight controls were enrolled. Along with anthropometric and standard biochemical profile genetic analys ...
... metabolic profile of young children and adolescents of Greek origin. DESIGN: One hundred and fifty-three overweight and obese Greek children (mean age 11.08±2.23 years) and 151 age-matched normal-weight controls were enrolled. Along with anthropometric and standard biochemical profile genetic analys ...
Blood Types worksheet
... Most genetic traits have a stronger, dominant allele and a weaker, recessive allele. In an individual with a heterozygous genotype, the dominant allele shows up in the offspring and the recessive allele gets covered up and doesn’t show; we call this complete dominance. However, some alleles don’t co ...
... Most genetic traits have a stronger, dominant allele and a weaker, recessive allele. In an individual with a heterozygous genotype, the dominant allele shows up in the offspring and the recessive allele gets covered up and doesn’t show; we call this complete dominance. However, some alleles don’t co ...
Greedy Algorithms And Genome Rearrangements
... Mouse vs Human Genome • Humans and mice have similar genomes, but their genes are ordered differently • ~245 rearrangements • Reversals • Fusions • Fissions • Translocation ...
... Mouse vs Human Genome • Humans and mice have similar genomes, but their genes are ordered differently • ~245 rearrangements • Reversals • Fusions • Fissions • Translocation ...
Human Cytomegalovirus UL34 Early and late Proteins Are Essential
... in transcript levels for all viral genes assayed (Figure 1B,C). UL32 and UL37 contain UL34 binding sites within their open reading frames; however, the diminution in transcript levels is consistent for all genes tested, regardless of the presence of a UL34 binding site. Intriguingly, the inability t ...
... in transcript levels for all viral genes assayed (Figure 1B,C). UL32 and UL37 contain UL34 binding sites within their open reading frames; however, the diminution in transcript levels is consistent for all genes tested, regardless of the presence of a UL34 binding site. Intriguingly, the inability t ...
First report of a tetracycline-inducible gene
... system to be functional in the ruminant pathogen, suggesting that this tetracycline-inducible promoter system might be of general use in mollicutes. ...
... system to be functional in the ruminant pathogen, suggesting that this tetracycline-inducible promoter system might be of general use in mollicutes. ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... The partial sequencing of the cloned gene from this strain was accomplished and sequence homology was analyzed. The alignment of the sequenced gene with gene sequences present in gene data bank showed two silent mutations, at nucleotide 676 and 701. However, two other nucleotide changes at position ...
... The partial sequencing of the cloned gene from this strain was accomplished and sequence homology was analyzed. The alignment of the sequenced gene with gene sequences present in gene data bank showed two silent mutations, at nucleotide 676 and 701. However, two other nucleotide changes at position ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... Ten monozygotic twin pairs who take part in longitudinal studies of the Netherlands Twin Register (NTR) were selected for the current study. There were five young twin pairs 36 whose buccal samples were collected when the twins were between ages 8 and 10 years and five adolescent pairs 37 who were a ...
... Ten monozygotic twin pairs who take part in longitudinal studies of the Netherlands Twin Register (NTR) were selected for the current study. There were five young twin pairs 36 whose buccal samples were collected when the twins were between ages 8 and 10 years and five adolescent pairs 37 who were a ...