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A genome-wide analysis of DNA methylation in buccal - VU-DARE
A genome-wide analysis of DNA methylation in buccal - VU-DARE

... Ten monozygotic twin pairs who take part in longitudinal studies of the Netherlands Twin Register (NTR) were selected for the current study. There were five young twin pairs 36 whose buccal samples were collected when the twins were between ages 8 and 10 years and five adolescent pairs 37 who were a ...
Gene ORGANizer: linking genes to the organs they
Gene ORGANizer: linking genes to the organs they

... if certain anatomical parts are over-represented in the ontology (because some phenotypes are easier to detect, or some diseases are more studied), it would not bias the results (2). Gene ORGANizer also allows users to enter their own background list. User-specified backgrounds are useful in cases w ...
Recitation Section 15 Answer Key Diploid Genetics and
Recitation Section 15 Answer Key Diploid Genetics and

... better survival for a species because, for any change in the environmental conditions (selective pressure), it increases the chances that an individual will arise that is better suited to the new conditions (selective advantage). This individual and the individual’s offspring will have be more likel ...
The application of molecular genetics to detection of
The application of molecular genetics to detection of

... Mele & Goldman, 19816). It is still not clear exactly how the genes involved in the failure of the palate to fuse, and potential thresholds to teratogenic agents, combine; large parts of the complex biochemical mechanisms are still only postulated at the theoretical level. There have been few defini ...
Dry bean collection from around the world helps
Dry bean collection from around the world helps

... other diseases, such as bacterial blights, fungal diseases, and viral diseases. A graduate student who is working at the Panhandle Center, Jorge Venegas, has found the gene that provides resistance to rust, as well as the molecular marker tied to the gene, Urrea said. “We have to have knowledge, acc ...
About OMICS Group
About OMICS Group

... Summary of gene expression A large proportion of the DEGs between Brassica hexaploid and its parents was involved in biosynthesis of secondary metabolites, plant-pathogen interaction, photosynthesis, and plant hormone signal transduction There were bigger differences on the level of gene express ...
The ROOT HAIRLESS 1 gene encodes a nuclear protein
The ROOT HAIRLESS 1 gene encodes a nuclear protein

... A group of genes involved in plant growth factor pathways also confer alterations in root hair patterning when mutated. The auxin resistant mutant axr2 (Wilson et al. 1990) that displays a greatly reduced number of root hairs belongs to this class, as does the ethylene signal transduction mutant ctr ...
DNA sequence annotation
DNA sequence annotation

... according to their length in the main string and in the complement string. In step 3 you will finalize if the potential gene is real gene. b. The list of the genes that have the length that less than 300 (probable pseudogenes) in increasing order according to their length in the main string and in t ...
Hereditary Angioedema
Hereditary Angioedema

... unpredictable episodic swellings which can affect the face, peripheries, genitals, abdomen and airway. Laryngeal swellings can result in death. As with many rare conditions, there is unfortunately often a delay to diagnosis during which time patients do not receive appropriate treatment. The vast ma ...
Clustering_PartII_2012
Clustering_PartII_2012

... HS + EtOH analysis (added 2 replicates of a new conditions): Only 1618 genes were DE (at any of the models) at FDR of 5% ??? Why so few when 3157 met this cutoff when HS was analyzed alone? baySeq paper: harder to call DE with “more complex” models ...
Characterization and transcript mapping of a bovine herpesvirus
Characterization and transcript mapping of a bovine herpesvirus

... some herpesviral tegument proteins m a y be glycosylated. It has been reported that herpes simplex virus type 1 (HSV-1) VP13/14 can bind lectins (Meredith et al., 1991), whereas equine herpesvirus type 4 (EHV-4) g p l 0 (Whittaker et al., 1991) and h u m a n cytomegalovirus (Benko et al., 1988) tegu ...
Affymetrix Data analysis
Affymetrix Data analysis

... > topTable(fit2, coef = "diff", adjust.method = "fdr") ...
recombiant drug
recombiant drug

... increase in glycolysis, and the synthesis of fat and glycogen. • It increases the synthesis of glycogen, not only by increasing facilitated diffusion of glucose in the cells, but also by stimulating the activity of the enzyme which catalyzes the synthesis. • It increases the synthesis of fatty aci ...
Segregation, Assortment, and Dominance Relationships
Segregation, Assortment, and Dominance Relationships

... for the appearance of a given trait  Contemporary understanding: ...
The Drosophila FoxP gene is necessary for operant self
The Drosophila FoxP gene is necessary for operant self

... P2 (FoxP2) cause a severe speech and language disorder. Downregulating the Zebrafinch FoxP2 orthologue in development results in incomplete and inaccurate song imitation. These forms of vocal learning exhibit two common characteristics: 1. Spontaneous initiation of behavior (‘trying out’); 2. Evalua ...
first of Chapter 11: Gene Regulation
first of Chapter 11: Gene Regulation

... lac operon model • 2 kinds of genes: structural, regulatory elements. • Polycistronic structural genes, with promoter and operator constitute the lac operon. • Promoter mutants make no lac mRNA. • lacI gene makes a repressor, which binds to the operator. • When operator is ‘repressed’ no transcript ...
Endocrine Disorders and the Heart
Endocrine Disorders and the Heart

... obtain them under standardized conditions. The most useful diagnostic test involves the oral administration of 75 to 100 g of glucose.19 In normal individuals, GH levels are less than 2 ng/mL, 90 to 120 minutes after administration of the test dose.47,48 Serum IGF-I levels, which correlate well with ...
Developing a CRISPR/Cas9 System for Volvox Carteri
Developing a CRISPR/Cas9 System for Volvox Carteri

... targeted mutations. The Cas9/CRISPR system is simpler and more precise than previously developed genome editing systems. The high precision is due to the CRISPR associated (Cas) endonuclease’s ability to bind DNA via associated guide RNAs. Cas endonucleases can delete or add bases to the genome, whi ...
Identification of a NodD repressible gene
Identification of a NodD repressible gene

... that of nodM and its expression was repressed by nodD. A deletion mutation was made and proteins produced by the mutant were compared with those by wild-type using 2D gel electrophoresis. Several protein differences were identified suggesting that this small gene influences the expression or stabili ...
14.1 The lacI Gene Encodes a Diffusible Repressor
14.1 The lacI Gene Encodes a Diffusible Repressor

... that can occur even though two DNA segments are not physically adjacent. The action of the lac repressor on the lac operon is a trans-effect. A regulatory protein, such as the lac repressor, is called a trans-acting factor. In contrast, a cis-acting element is a DNA segment that must be adjacent to ...
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish

... changes of four amino acids and a premature termination resulting in the loss of eight amino acids at the Cterminus of cyp19a in the sequence of accession AF004521. The other sequence in GenBank (accession number AF120031) is a partial sequence. It differs from our cyp19b (accession number AF183908) ...
GENERATION OF BANK POST-TRANSCRIPTIONAL FUSIONS OF
GENERATION OF BANK POST-TRANSCRIPTIONAL FUSIONS OF

... more microorganisms how Azotobacter vinelandii, that is a bacterium gram-negative, pleomorphic it can be two forms, dyads or cysts. The two metabolites are of importance industry, with PHB can be made surgical suture threads, as they are biodegradable in the human body. And whit alginate is used to ...
Proportionality between variances in gene expression induced by
Proportionality between variances in gene expression induced by

... associated with several genes, as known as epistasis. Even if a fitness value may be directly related to a single phenotype or the expression of a single gene, many genes may modify the expression of each other. These expressions are interrelated through a complex gene regulation network; therefore, ...
Genetic tasks V: GENE INTERACTIONS
Genetic tasks V: GENE INTERACTIONS

... 2. The colour of a feather of a canary is determined by genes A and B. Dominant allele of gene A encodes for red colour, dominant allele of gene B for yellow one. Birds with genotypes aabb and A-B- are white. a) Use colours in Punnet square (or branching method) to differentiate phenotypes resultin ...
Lecture 5
Lecture 5

... Trees can also tell you about genes • What organisms have the gene? • Where did the gene come from? • What happens to the gene once it’s there? Duplicate - tandem - mRNA can be inserted Lost ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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