ppt檔案
... The versions of for in these species affect the level of PKG The genes are orthologues - they descended from the same ancestral gene and have the same function But, for and PKG affects foraging through different mechanisms and may be regulated differently in species ...
... The versions of for in these species affect the level of PKG The genes are orthologues - they descended from the same ancestral gene and have the same function But, for and PKG affects foraging through different mechanisms and may be regulated differently in species ...
Genet Mol Res, 13 - Funpec-RP
... OPLL. Among these proposed candidate genes, we chose to further investigate the BMP-2 and COL6A1 genes to test our hypothesis that they are associated with OPLL in Korean patients and their unaffected family members. Several population-based epidemiological studies in Japan have reported a prevalenc ...
... OPLL. Among these proposed candidate genes, we chose to further investigate the BMP-2 and COL6A1 genes to test our hypothesis that they are associated with OPLL in Korean patients and their unaffected family members. Several population-based epidemiological studies in Japan have reported a prevalenc ...
Graphical Exploration of Gene Expression Data: A
... It is often advantageous to re-express (i.e. transform) the data as logarithms, i.e. a new matrix A is obtained whose elements aij = log xij . For this operation to be valid, measurements must be made on a ratio scale and the values must be positive. Logarithmic re-expression allows data in differen ...
... It is often advantageous to re-express (i.e. transform) the data as logarithms, i.e. a new matrix A is obtained whose elements aij = log xij . For this operation to be valid, measurements must be made on a ratio scale and the values must be positive. Logarithmic re-expression allows data in differen ...
Additional file 1
... profile in WIGGLE format then use z-scores to call enriched regions. Combine the signals from different array platform or design, use metaanalysis to call enriched regions. Based on MM-ChIP algorithm. Combine different libraries with different fragment sizes, and use a MACS-like algorithm to find th ...
... profile in WIGGLE format then use z-scores to call enriched regions. Combine the signals from different array platform or design, use metaanalysis to call enriched regions. Based on MM-ChIP algorithm. Combine different libraries with different fragment sizes, and use a MACS-like algorithm to find th ...
History of Disease Gene Mapping
... Later confirmed by Elston, Berg. This demonstrated existence of a disease gene in the vicinity of C3 (chrom. 19) Work by Joe Goldstein and Michael Brown (Nobel prize in 1985) identified disease as defect in LDL receptor; located on chromosome 19. Now drugs (statins) have been developed for lowering ...
... Later confirmed by Elston, Berg. This demonstrated existence of a disease gene in the vicinity of C3 (chrom. 19) Work by Joe Goldstein and Michael Brown (Nobel prize in 1985) identified disease as defect in LDL receptor; located on chromosome 19. Now drugs (statins) have been developed for lowering ...
Effects of cis and trans Genetic Ancestry on Gene Expression in
... gene expression levels in populations of different continental ancestry and reported population differences at a large number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines ...
... gene expression levels in populations of different continental ancestry and reported population differences at a large number of genes. However, these differences could largely be due to non-genetic (e.g., environmental) effects. Here, we analyze gene expression levels in African American cell lines ...
WHAT IS GENE THERAPY? CHOOSING TARGETS FOR GENE
... children with X-linked Severe Combined Immune Deficiency (SCID). People with this disorder have virtually no immune protection against bacteria and viruses. To escape infections and illnesses, they must live in a completely germ-free environment. In the late 1990s, researchers tested a gene therapy ...
... children with X-linked Severe Combined Immune Deficiency (SCID). People with this disorder have virtually no immune protection against bacteria and viruses. To escape infections and illnesses, they must live in a completely germ-free environment. In the late 1990s, researchers tested a gene therapy ...
Control of reproduction by Polycomb Group complexes in animals
... through a specialised interface, the placenta in mammals and the endosperm in flowering plants. The placenta develops from a specific mass of cell, the trophoblast, set apart after the first divisions of the embryo. The endosperm is the product of fertilisation of a secondary female gamete, the cent ...
... through a specialised interface, the placenta in mammals and the endosperm in flowering plants. The placenta develops from a specific mass of cell, the trophoblast, set apart after the first divisions of the embryo. The endosperm is the product of fertilisation of a secondary female gamete, the cent ...
Small GTP-binding protein PdRanBP regulates vascular tissue
... transcribed in the lignified xylem [31]. These studies have significantly improved our understanding of secondary xylem differentiation and secondary wall formation. Populus deltoides (Marsh.), which is widely distributed between the northern latitudes of 40° to 60° in North America, was introduced ...
... transcribed in the lignified xylem [31]. These studies have significantly improved our understanding of secondary xylem differentiation and secondary wall formation. Populus deltoides (Marsh.), which is widely distributed between the northern latitudes of 40° to 60° in North America, was introduced ...
Genes Involved in the Seminoma Testicular Cancer
... are testicular tumors of germ cells. The main way to detect this cancer usually begins with a physical exam, which seeks swelling, tenderness or any foreign lump in the testicles; however, the diagnosis is confirmed or rejected through blood tests or ultrasound (Moreno et al., 2014). The two main ty ...
... are testicular tumors of germ cells. The main way to detect this cancer usually begins with a physical exam, which seeks swelling, tenderness or any foreign lump in the testicles; however, the diagnosis is confirmed or rejected through blood tests or ultrasound (Moreno et al., 2014). The two main ty ...
Expression of the Mitochondrial ATPase6 Gene and Tfam in Down
... should be further evaluated. Moreover, just as mitochondrial transfer between oocytes can increase pregnancy rate by increasing mitochondrial function, so ooplasmic transfer may increase the possibility of a having a healthy baby in an ensuing pregnancy in older women who harbor the risk of Down syn ...
... should be further evaluated. Moreover, just as mitochondrial transfer between oocytes can increase pregnancy rate by increasing mitochondrial function, so ooplasmic transfer may increase the possibility of a having a healthy baby in an ensuing pregnancy in older women who harbor the risk of Down syn ...
The silence of genes
... imprinting is mediated by the methylation of cytosine–phosphate–guanine (CpG) sites in the DNA sequence. Methyl groups inhibit expression by preventing the transcription machinery from attaching to the DNA. These sites, comprising alternating C and G without any adenine or thymine, are relatively sp ...
... imprinting is mediated by the methylation of cytosine–phosphate–guanine (CpG) sites in the DNA sequence. Methyl groups inhibit expression by preventing the transcription machinery from attaching to the DNA. These sites, comprising alternating C and G without any adenine or thymine, are relatively sp ...
Molecular and Cellular Biology, September 2000, p
... control of a specific group of genes encoding chromatin-associated proteins (such as H10), these molecules may regulate chromatin structure and function. Transcription factors interacting with the H10 promoter are presumably part of this regulatory cascade and are believed to link cell cycle control ...
... control of a specific group of genes encoding chromatin-associated proteins (such as H10), these molecules may regulate chromatin structure and function. Transcription factors interacting with the H10 promoter are presumably part of this regulatory cascade and are believed to link cell cycle control ...
209 Original Scientific Article THE INFLUENCE OF
... embryos into the nucleus at the 8-cell stage (4, 9). At the 16-cell stage, DNMT1 enzymes are localized only in the cytoplasm. The timing of the DNMT1 migration into the nucleus coincides with the major genome activation, suggesting that the DNMT3a and DNMT3b genes are activated at the same time. DNM ...
... embryos into the nucleus at the 8-cell stage (4, 9). At the 16-cell stage, DNMT1 enzymes are localized only in the cytoplasm. The timing of the DNMT1 migration into the nucleus coincides with the major genome activation, suggesting that the DNMT3a and DNMT3b genes are activated at the same time. DNM ...
X-inactivation and human disease
... from a family displaying a clear X-linked dominant inheritance of the disease [12]; and a newborn male born at term, but who died 4 hours after birth with typical signs of OFDI, including cystic kidneys [13]. The OFD1 gene encodes a 1011 amino acid protein, which is expressed during development and ...
... from a family displaying a clear X-linked dominant inheritance of the disease [12]; and a newborn male born at term, but who died 4 hours after birth with typical signs of OFDI, including cystic kidneys [13]. The OFD1 gene encodes a 1011 amino acid protein, which is expressed during development and ...
Quantitative PCR for the Detection of BCR
... Quantitative PCR has been demonstrated (9, 10). Many studies have confirmed that sequential analysis of residual disease by Q-PCR for BCR-ABL transcripts has the advantage of monitoring the dynamics of CML. Performed at regular intervals, Q-PCR can indicate the activity of a malignant clone, thus pr ...
... Quantitative PCR has been demonstrated (9, 10). Many studies have confirmed that sequential analysis of residual disease by Q-PCR for BCR-ABL transcripts has the advantage of monitoring the dynamics of CML. Performed at regular intervals, Q-PCR can indicate the activity of a malignant clone, thus pr ...
WJG-23-1787
... illustrated in Figure 4A to identify the miRNA-mRNA regulatory network in L02 cells transfected with HBx. Through analysis using miRnada and TargetScan software, potential miRNA targets were successfully predicted. In combination with the expression pattern of target genes (Figure 1A), we generated ...
... illustrated in Figure 4A to identify the miRNA-mRNA regulatory network in L02 cells transfected with HBx. Through analysis using miRnada and TargetScan software, potential miRNA targets were successfully predicted. In combination with the expression pattern of target genes (Figure 1A), we generated ...
cis-Regulatory Elements and Chromatin State
... animal PRC1 core component Sex Combs Extra (Xu and Shen, ...
... animal PRC1 core component Sex Combs Extra (Xu and Shen, ...
Transvection in 2012: Site-Specific Transgenes Reveal a
... N Drosophila, homologous chromosomes are paired in somatic cells (reviewed in McKee 2004), leading to the opportunity for regulatory DNA on one chromosome to influence the expression of a promoter located on the homologous chromosome (reviewed in Duncan 2002; Kennison and Southworth 2002). Such trans ...
... N Drosophila, homologous chromosomes are paired in somatic cells (reviewed in McKee 2004), leading to the opportunity for regulatory DNA on one chromosome to influence the expression of a promoter located on the homologous chromosome (reviewed in Duncan 2002; Kennison and Southworth 2002). Such trans ...
Cancer Prone Disease Section Waardenburg syndrome (WS) Atlas of Genetics and Cytogenetics
... Microphtalmia-associated transcription factor (MITF) is a basic helix-loop-helix, leucin zipper transcription factor that plays a pivotal role in survival and differentiation of melanocytes, the cells that produce melanin pigments. MITF has been demonstrated to upregulate the expression of the genes ...
... Microphtalmia-associated transcription factor (MITF) is a basic helix-loop-helix, leucin zipper transcription factor that plays a pivotal role in survival and differentiation of melanocytes, the cells that produce melanin pigments. MITF has been demonstrated to upregulate the expression of the genes ...
PDF
... determined interactions are direct. We focused on cis-regulatory networks responsible for the Ciona mesodermal tissues by examining how the networks specify these tissues at the level of their cis-regulatory architecture. We also found many interactions that had not been predicted by simple gene kno ...
... determined interactions are direct. We focused on cis-regulatory networks responsible for the Ciona mesodermal tissues by examining how the networks specify these tissues at the level of their cis-regulatory architecture. We also found many interactions that had not been predicted by simple gene kno ...
COAT AND COLOUR GENES IN DACHSHUNDS
... pattern. Black stripes may appear ONLY on a red background (body or tan markings). Requires only one gene “ebr” for reproduction, but one parent must be “brindle” to produce “brindle”offspring. ...
... pattern. Black stripes may appear ONLY on a red background (body or tan markings). Requires only one gene “ebr” for reproduction, but one parent must be “brindle” to produce “brindle”offspring. ...
Investigating the molecular mechanisms behind flowering in
... a number of factors; including, irrigation after periods of drought, pruning and application of nitrogen fertiliser. Floral induction in mango is caused by low temperatures (<20°C), the low temperatures are perceived by the mature leaves and a signal is sent via the phloem to the bud. If buds are in ...
... a number of factors; including, irrigation after periods of drought, pruning and application of nitrogen fertiliser. Floral induction in mango is caused by low temperatures (<20°C), the low temperatures are perceived by the mature leaves and a signal is sent via the phloem to the bud. If buds are in ...
Hyperglycemia and Acute Coronary SyndromeA Scientific Statement
... associated with increased markers of vascular inflammation. Both in vitro and in vivo studies have linked hyperglycemia with elevated levels of C-reactive protein, interleukin-6, and tumor necrosis factor-␣.45,46 Tumor necrosis factor-␣ has been shown to extend infarct size in laboratory animals and ...
... associated with increased markers of vascular inflammation. Both in vitro and in vivo studies have linked hyperglycemia with elevated levels of C-reactive protein, interleukin-6, and tumor necrosis factor-␣.45,46 Tumor necrosis factor-␣ has been shown to extend infarct size in laboratory animals and ...