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Genetic regulation in eukaryotes
Genetic regulation in eukaryotes

... SLIDES 12-14 MicroRNAs (miRNAs). A continuously increasing number of miRNAs have been described in the genomes of several multicellular organisms. Micro RNA genes yield RNA transcripts that are processed into short single-stranded segments, which then double over on themselves to form hairpin struct ...
From DNA to Protein: Genotype to Phenotype Reading Assignments
From DNA to Protein: Genotype to Phenotype Reading Assignments

... Beadle and Tatum’s evidence for the one gene-one enzyme hypothesis ...
Mechanism of ribonuclease
Mechanism of ribonuclease

... Mechanism of ribonuclease ...
Recovery and analysis of old/ancient DNA: molecular archaeology
Recovery and analysis of old/ancient DNA: molecular archaeology

... Concern over potential harm (to health and/or environment) from these markers has driven development of other methods – manA gene: confers growth on the sugar mannose as a sole ...
GENES
GENES

a15 GenesFormFunc
a15 GenesFormFunc

... – They exhibit some, but not all, characteristics of living organisms – They are made of DNA or RNA surrounded by a protein coating. Some also have envelopes outside their protein coat – They are incredibly small (< 1 um) ...
The Unseen Genome
The Unseen Genome

... a mate that yields antisense RNAs. These competing RNAs may suppress a gene just by tying up the gene's messenger RNA. But Rotman speculates that they employ a built-in genome censor, known as the RNA interference machinery. Scientists are still enthralled by the discovery several years ago of this ...
Lecture 8 - Brandeis Life Sciences
Lecture 8 - Brandeis Life Sciences

Lecture 12 - U of L Class Index
Lecture 12 - U of L Class Index

... Spacers surrounding individual rRNAs genes are complementary and can form an extended hairpin; the double stranded region will serve as a target for RNAase III ...
LecCh6Annotation
LecCh6Annotation

... Noncoding RNA (ncRNA) • ncRNA represent 98% of all transcripts in a mammalian cell • ncRNA have not been taken into account in gene counts • cDNA • ORF computational prediction • Comparative genomics looking at ORF ...
RNA Transcription
RNA Transcription

... DNA (colored shapes). ...
lecture1
lecture1

... – Every sequence can thus be read in three reading frames. With doublestranded DNA there are six possible reading frames. three in the forward orientation on one strand and three reverse (on the opposite strand). – If the DNA is eukaryotic, the reading frame may contain introns. ...
View PDF
View PDF

... To prevent any error in the protein translation process from gene and RNA, eukaryotic (and prokaryotic) cells have developed sophisticated proofreading mechanisms, i.e. specific enzymes called RNA polymerases that are capable of backtracking thereby minimizing the number of single nucleotide base mu ...
Eukaryotic Transcription In all species, transcription begins with the
Eukaryotic Transcription In all species, transcription begins with the

... RNA polymerase traverses the template strand from 3' → 5', the coding (nontemplate) strand and newly-formed RNA can also be used as reference points, so transcription can be described as occurring 5' → 3'. This produces an RNA molecule from 5' → 3', an exact copy of the coding strand (except that th ...
DNA
DNA

... • Just like the alphabet has 26 letters to make all the words we know, the 20 amino acids make all the different proteins found in living organisms •This makes it possible to have 64 different combinations for amino acids • The codons are the template for protein synthesis •Protein synthesis is the ...
Document
Document

... In this module you will investigate protein synthesis, a process in which cells build proteins. Translation is the term used to describe this process, as the sequences of DNA nucleotides are transcribed and translated by a various forms of RNA into the specific protein coded for by that gene sequenc ...
et al
et al

Protein Synthesis
Protein Synthesis

RNA Viruses
RNA Viruses

... a nested set of RNAs - all share short 5’ sequence and a 7 base sequence but have unique AUG site and share 3’ end of genome • May be produced by jumping polymerase - 7 base sequence in various parts of genome – Get recombinant viruses with mixed infections – DI particles are common ...
BIOL 2416 Genetics
BIOL 2416 Genetics

... RNAi mechanism is triggered by – Exogenous molecules: Viral DNA or dsRNA coming in from the outside – Endogenous molecules (from the inside): • aberrant transcripts from transposons or repetitive regions • Pre-miRNA molecules transcribed form e.g. introns ...
C - Bioinformatics Research Center
C - Bioinformatics Research Center

... Life depends on three critical molecules • DNAs • Hold information on how cell works ...
No Slide Title
No Slide Title

... any RNA or DNA out there • Nucleases can’t get through the nuclear envelope so DNA is safe • mRNA sent out into the cytoplasm must be protected – Methyl cap is a block – Poly A tail is a fuse ...
MOLECULAR BIOLOGY.rtf
MOLECULAR BIOLOGY.rtf

... RNA (ribonucleic acid) continued Transcription—copies one of the DNA strands from the 3’end, and makes RNA beginning at its 5’end. The new RNA is complementary (A=U and G=C) and antiparallel to the coding strand of DNA Transcription is catalyzed in the nucleus by RNA polymerase 3 types of RNA mRNA—I ...
tRNA
tRNA

Chapter 17 Guided Notes
Chapter 17 Guided Notes

... or by ___________________________________________________________________________. ○ Each tRNA molecule bears a ________________________________________________ at one end. ○ At the other end of the tRNA is a nucleotide triplet called an _______________________________, which base-pairs with a _____ ...
< 1 ... 158 159 160 161 162 163 164 165 166 ... 225 >

RNA silencing

RNA silencing (associated with the concept of post-transcriptional gene silencing or RNA interference) refers to a family of gene silencing effects by which the expression of one or more genes is downregulated or entirely suppressed by non-coding RNAs, particularly small RNAs. It may also refer to the introduction of a synthetic antisense RNA molecule used in scientific experiments on gene expression. RNA silencing may also be defined as sequence-specific regulation of gene expression triggered by double-stranded RNA (dsRNA). RNA silencing mechanisms are highly conserved in most eukaryotes. The most common and well-studied example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the degradation of complementary messenger RNA. Other classes of small RNA have been identified, including piwi-interacting RNA (piRNA) and its subspecies repeat associated small interfering RNA (rasiRNA).
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