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Pulling forces acting on Hox gene clusters cause expression
Pulling forces acting on Hox gene clusters cause expression

... of their importance in axial patterning, several homologue clus- ...
Proprietary Databases
Proprietary Databases

... The Personalis Regulatory Regions Database contains several hundred thousand putative transcription factor binding sites/regulatory regions. These regulatory annotations enable us to interpret intergenic and other non-coding variants that may have a significant impact on gene expression and function ...
Microarray Image Data Analysis
Microarray Image Data Analysis

... • Criterion for Differentially Expressed is defined as log2(Lowess normalized ratio of Cy3/Cy5) is greater than T (↑) or less than ...
Reptile_Tables_Headings
Reptile_Tables_Headings

... The information given in this table incorporates many changes made to the start and stop points of these genes in order to provide consistency between reptile mitochondrial (mt) genomes. The lengths of the intergenic spacers include the stop codons of the protein-coding genes (i.e. proteincoding gen ...
Regulatory sequences
Regulatory sequences

... and Y sequences conserved in all MHC-II, Ii, and HLA-DM promoters. RFX, X2BP, NF-Y, and an as yet undefined W-binding protein bind cooperatively to these sequences and assemble into a stable higher order nucleoprotein complex referred to here as the MHC-II enhanceosome. CIITA is tethered to the enha ...
How to measure DNA methylation
How to measure DNA methylation

Lecture 12 - U of L Class Index
Lecture 12 - U of L Class Index

... Spacers surrounding individual rRNAs genes are complementary and can form an extended hairpin; the double stranded region will serve as a target for RNAase III ...
Chapter 17
Chapter 17

... Myotonic dystrophy (MD), occurring in about 1 of 8000 individuals, is the most common form of muscular dystrophy in adults. The disease, which is characterized by progressive muscle degeneration, is caused by a dominant mutant gene that contains an expanded CAG repeat region. Wild-type alleles of t ...
Hox Genes in Development and Disease – Lecture 2
Hox Genes in Development and Disease – Lecture 2

Document
Document

Feature subset selection/ ANOVA
Feature subset selection/ ANOVA

... 22. We will now do a similar analysis to the one we just did by using SAM, and instead of doing unpaired analysis we will do a paired analysis. Make sure the dataset “Log(2) Quantile normalized intensity data” is selected. ...
The BCM Microarray Core Facility
The BCM Microarray Core Facility

... PAIRED-END SEQUENCING ...
Leukaemia Section del(11)(p12p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section del(11)(p12p13) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... RAG2-LMO2 fusion gene, bringing the LMO2 gene under the control of RAG2 promoter sequences. However, it was shown that promoter substitution was not the main activational mechanism as none of the other del(11)(p12p13) positive cases showed a similar RAG2-LMO2 fusion gene. In addition, RQ-PCR analysi ...
Linkage
Linkage

Chromatin Structure 1
Chromatin Structure 1

No Slide Title
No Slide Title

... - do not take into account biological knowledge - predictions are not disease specific. ...
persist. Fruit flies, on the other hand, models of speciation, genetic
persist. Fruit flies, on the other hand, models of speciation, genetic

... already in contact with a nuclear speckle (Figure 1) [7]. Thus, the association of the HSP70 locus to a speckle is directly or indirectly actin-dependent and contributes to its transcription. Speckles, first described as storage/ modification sites of the splicing machinery, may also be enriched in ...
Specific function of a plastid sigma factor for ndhF
Specific function of a plastid sigma factor for ndhF

... transcription by NEP as well as PEP enzymes or specific regulation of transcription by NEP/PEP competition for a promoter region containing overlapping promoters. Wellcharacterized examples for such multiple promoter regions are those directing the psbD-psbC, rrn, atpB, atpI and clpP genes (15–21). ...
RNA Processing in Eukaryotes
RNA Processing in Eukaryotes

... exons, which correspond to protein-coding sequences (ex-on signies that introns (int-ron denotes their intervening role), which ...
IOSR Journal of Computer Engineering (IOSR-JCE)
IOSR Journal of Computer Engineering (IOSR-JCE)

Disease Inheritance
Disease Inheritance

... “sporadic,” polygenic inheritance could be responsible for some of these cases. Some characteristics, such as skin colour in humans, are thought to be due to at least three genes inherited from each parent (making at least six genes responsible for an individual’s skin colour). As each of these gene ...
Low dose irradiation profoundly affects transcriptome and
Low dose irradiation profoundly affects transcriptome and

... expression of actin cross-linking protein, transgelin, which may contribute to the replicative senescence. The MiR34 family is known to be activated by the p53-dependant pathway in response to DNA damage. ...
Genoombrowsers - Radboud Universiteit
Genoombrowsers - Radboud Universiteit

... • Sequence variations within a species • Similar to mutations, but are simultaneously present in the population, and generally have ...
a π i, π i+1
a π i, π i+1

... • A genome of length n is comprised of (n/3) codons • Stop codons break genome into segments between consecutive Stop codons • The subsegments of these that start from the Start codon (ATG) are ORFs • ORFs in different frames may overlap ATG ...
Fun with Nif`s
Fun with Nif`s

... • Then, Let us compare its genes to genes of Anabaena. ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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