Mechanisms of Transcription-Replication
... are virtually identical to those for the P7 promoter (compare Fig. 4B to Fig. 3D). Since very different promoters cause similar inhibitory effects on replication, it is likely that the act of transcription, rather than the nature of a promoter, is responsible for this effect. When the trc promoter w ...
... are virtually identical to those for the P7 promoter (compare Fig. 4B to Fig. 3D). Since very different promoters cause similar inhibitory effects on replication, it is likely that the act of transcription, rather than the nature of a promoter, is responsible for this effect. When the trc promoter w ...
Transcriptional regulation of mammalian autophagy at a glance
... BNIP3, and was also shown to indirectly regulate the transcription of ATG5 (Polager et al., 2008) (see poster). BNIP3 acts as a positive regulator of autophagy by disrupting the B-cell lymphoma 2 (BCL2)-mediated inhibition of beclin 1 (Tracy et al., 2007). Nuclear factor kappa-light-chain-enhancer o ...
... BNIP3, and was also shown to indirectly regulate the transcription of ATG5 (Polager et al., 2008) (see poster). BNIP3 acts as a positive regulator of autophagy by disrupting the B-cell lymphoma 2 (BCL2)-mediated inhibition of beclin 1 (Tracy et al., 2007). Nuclear factor kappa-light-chain-enhancer o ...
Boundary elements and nuclear organization
... may function as genomic insulators, are frequently found at the borders between bands and interbands of polytene chromosomes, suggestive of their role in this type of partitioning (M. Labrador and V. Corces, unpublished observations). The chicken b-globin 5′ HS4 insulator is present at the border be ...
... may function as genomic insulators, are frequently found at the borders between bands and interbands of polytene chromosomes, suggestive of their role in this type of partitioning (M. Labrador and V. Corces, unpublished observations). The chicken b-globin 5′ HS4 insulator is present at the border be ...
The enhancement of ribosomal transcription by the recycling of RNA
... pX1108c in the same orientation as the wild type terminator, (pXUGlc), a second with two terminators inserted tandemly in this orientation, (pXHG2c) and a third with the terminator inserted into, pXl^ESlc in the corresponding position but the opposite orientation, (pXUGllc). Each construct was micro ...
... pX1108c in the same orientation as the wild type terminator, (pXUGlc), a second with two terminators inserted tandemly in this orientation, (pXHG2c) and a third with the terminator inserted into, pXl^ESlc in the corresponding position but the opposite orientation, (pXUGllc). Each construct was micro ...
Gene regulation in three dimensions
... Gene regulation has traditionally mainly been viewed as a 1D and possibly 2D process. In the 1D view the genome is seen as a linear string of nucleotides, where one or more transcription factors (TFs) bind to transcription factor binding sites (TFBSs), and thereby regulate the expression of genes th ...
... Gene regulation has traditionally mainly been viewed as a 1D and possibly 2D process. In the 1D view the genome is seen as a linear string of nucleotides, where one or more transcription factors (TFs) bind to transcription factor binding sites (TFBSs), and thereby regulate the expression of genes th ...
operon
... • There are two types of mutations in the lacI gene • Some mutants fail to produce any of the lac enzymes whether or not inducer is present • These are called superrepressor mutants (Is) • The repressor remains bound to the operator whether or not inducer is present © 2012 Pearson Education, Inc. ...
... • There are two types of mutations in the lacI gene • Some mutants fail to produce any of the lac enzymes whether or not inducer is present • These are called superrepressor mutants (Is) • The repressor remains bound to the operator whether or not inducer is present © 2012 Pearson Education, Inc. ...
RNA Polymerase I-Specific Subunit CAST/hPAF49 Has a Role in the
... PAF49. We provide evidence for growth-regulated Tyr phosphorylation of CAST/hPAF49, specifically in initiation-competent Pol I complexes in HeLa cells, at a conserved residue also known to be important for signaling during T-cell activation. CAST/hPAF49 can interact with activator upstream binding ...
... PAF49. We provide evidence for growth-regulated Tyr phosphorylation of CAST/hPAF49, specifically in initiation-competent Pol I complexes in HeLa cells, at a conserved residue also known to be important for signaling during T-cell activation. CAST/hPAF49 can interact with activator upstream binding ...
WS Procs 975 x 65
... representation to the Dependency Pattern Sets (DPS) representation. DPS representation is a generalized model of string representation, which can model adjacent nucleotide dependency. Although it has a lower descriptive power than SPSP representation, experimental results on real biological data sho ...
... representation to the Dependency Pattern Sets (DPS) representation. DPS representation is a generalized model of string representation, which can model adjacent nucleotide dependency. Although it has a lower descriptive power than SPSP representation, experimental results on real biological data sho ...
Factor of Transcription by Upstream Binding CAST/hPAF49 Has a
... PAF49. We provide evidence for growth-regulated Tyr phosphorylation of CAST/hPAF49, specifically in initiation-competent Pol I complexes in HeLa cells, at a conserved residue also known to be important for signaling during T-cell activation. CAST/hPAF49 can interact with activator upstream binding ...
... PAF49. We provide evidence for growth-regulated Tyr phosphorylation of CAST/hPAF49, specifically in initiation-competent Pol I complexes in HeLa cells, at a conserved residue also known to be important for signaling during T-cell activation. CAST/hPAF49 can interact with activator upstream binding ...
Analysis of acid-induced asr gene promoter of Enterobacteriaceae
... PhoB binding site (pho box). Transcription factor binding sites in bacterial genomes are usually long, consisting of ~30 bases and variable. Often most of their regulatory sequences are carried in two conserved subregions, each about 6 bases in length [16], which contain the predominant contacts wit ...
... PhoB binding site (pho box). Transcription factor binding sites in bacterial genomes are usually long, consisting of ~30 bases and variable. Often most of their regulatory sequences are carried in two conserved subregions, each about 6 bases in length [16], which contain the predominant contacts wit ...
Structural and Functional Studies of Insertion Element IS200
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
Landick R, Yanofsky C. 1987. Transcription
... attenuator. This decision is based on the cellular level of charged tRNA Trp. Under starvation conditions, in which all tRNATrp essentially is uncharged, the rate of read through transcription at the attenuator increases about eightfold over the rate observed when tRNATrp is fully charged. We do not ...
... attenuator. This decision is based on the cellular level of charged tRNA Trp. Under starvation conditions, in which all tRNATrp essentially is uncharged, the rate of read through transcription at the attenuator increases about eightfold over the rate observed when tRNATrp is fully charged. We do not ...
Domains of the Adenovirus E1A Protein Required for
... Received January 16, 1991; revised version accepted May 9, 1991. ...
... Received January 16, 1991; revised version accepted May 9, 1991. ...
Presentation - people.vcu.edu
... Myelin-associated glycoprotein (MAG) Acts as a linker between the axon and the myelin sheath ...
... Myelin-associated glycoprotein (MAG) Acts as a linker between the axon and the myelin sheath ...
GhMYB25-like: a key regulator of early cotton fiber development.
... and that had an expression profile similar to GhMYB25 (Wu et al., 2006). It was designated GhMYB25-like. In this study we examine the role of GhMYB25-like in fiber development using RNAi-mediated gene silencing and a transgenic cotton line containing an extra copy of GhMYB25-like under the control o ...
... and that had an expression profile similar to GhMYB25 (Wu et al., 2006). It was designated GhMYB25-like. In this study we examine the role of GhMYB25-like in fiber development using RNAi-mediated gene silencing and a transgenic cotton line containing an extra copy of GhMYB25-like under the control o ...
Enhancement of Nuclear Factor- B Acetylation by Coactivator p300
... Nuclear factor (NF)-B transcription factors are involved in the control of a large number of normal cellular and organismal processes, such as immune and inflammatory responses, developmental processes, cellular growth, and apoptosis. Transcription of the human immunodeficiency virus type 1 (HIV-1) ...
... Nuclear factor (NF)-B transcription factors are involved in the control of a large number of normal cellular and organismal processes, such as immune and inflammatory responses, developmental processes, cellular growth, and apoptosis. Transcription of the human immunodeficiency virus type 1 (HIV-1) ...
Increased transcription rates correlate with increased reversion rates
... and 0?05 M KH2PO4 substituted for 0?04 M sodium phosphate buffer (pH 6?5). When cells were to be starved for an amino acid, it was present at 0?2 mM in the growth medium. When cultures reached an OD550 of 0?1, they were labelled with 100 mCi (3?7 MBq) H332PO4 ml21 (ICN; 3?76106 Bq ml21) and then gro ...
... and 0?05 M KH2PO4 substituted for 0?04 M sodium phosphate buffer (pH 6?5). When cells were to be starved for an amino acid, it was present at 0?2 mM in the growth medium. When cultures reached an OD550 of 0?1, they were labelled with 100 mCi (3?7 MBq) H332PO4 ml21 (ICN; 3?76106 Bq ml21) and then gro ...
Document
... … the number of new proteincoding genes found by us has been revised from 5154 to 2222… – FANTOM/RIKEN Consortium Science, March 2006 Brendan Frey ...
... … the number of new proteincoding genes found by us has been revised from 5154 to 2222… – FANTOM/RIKEN Consortium Science, March 2006 Brendan Frey ...
Jigsaw handout - the Biology Scholars Program Wiki
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
Gene silencing in mammalian cells and the spread of DNA
... (Turker et al., 1989). These observations can best be explained by assuming that methylation for CpG sites on a given allele can be either gained or lost. By combining the results from the above studies, I proposed a model depicting a ‘dynamic equilibrium’ between forces that support the spread of D ...
... (Turker et al., 1989). These observations can best be explained by assuming that methylation for CpG sites on a given allele can be either gained or lost. By combining the results from the above studies, I proposed a model depicting a ‘dynamic equilibrium’ between forces that support the spread of D ...
PowerPoint-Präsentation
... al, 2009). The alternative sigma factor RpoH was discovered in the context of the heat-shock response in E. coli (Erickson et al, 1987; Grossman et al, 1984) and subsequently identified in P. aeruginosa (Allan et al, 1988; Benvenisti et al, 1995) and many other Gram-negative bacteria (Nakahigashi et ...
... al, 2009). The alternative sigma factor RpoH was discovered in the context of the heat-shock response in E. coli (Erickson et al, 1987; Grossman et al, 1984) and subsequently identified in P. aeruginosa (Allan et al, 1988; Benvenisti et al, 1995) and many other Gram-negative bacteria (Nakahigashi et ...
Coagulation in vitro
... useful model for coagulation, more recent evidence has shown that the pathways are not, in fact, redundant but are highly interconnected. For example, the tissue factor/VIIa complex activates not only factor X (as shown in Fig. 3) but also factor IX of the intrinsic pathway. Furthermore, patients wi ...
... useful model for coagulation, more recent evidence has shown that the pathways are not, in fact, redundant but are highly interconnected. For example, the tissue factor/VIIa complex activates not only factor X (as shown in Fig. 3) but also factor IX of the intrinsic pathway. Furthermore, patients wi ...
Salmonella
... In Salmonella, there are three classes of promoters in the flagellar transcriptional hierarchy. This organization allows genes needed earlier in the construction of flagella to be transcribed before genes needed later. Four operons (fliAZY, flgMN, fliDST, and flgKL) are expressed from both class 2 and cla ...
... In Salmonella, there are three classes of promoters in the flagellar transcriptional hierarchy. This organization allows genes needed earlier in the construction of flagella to be transcribed before genes needed later. Four operons (fliAZY, flgMN, fliDST, and flgKL) are expressed from both class 2 and cla ...
Transcription factor
In molecular biology and genetics, a transcription factor (sometimes called a sequence-specific DNA-binding factor) is a protein that binds to specific DNA sequences, thereby controlling the rate of transcription of genetic information from DNA to messenger RNA. Transcription factors perform this function alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription of genetic information from DNA to RNA) to specific genes.A defining feature of transcription factors is that they contain one or more DNA-binding domains (DBDs), which attach to specific sequences of DNA adjacent to the genes that they regulate. Additional proteins such as coactivators, chromatin remodelers, histone acetylases, deacetylases, kinases, and methylases, while also playing crucial roles in gene regulation, lack DNA-binding domains, and, therefore, are not classified as transcription factors.