MEF2 activity during embryogenesis - Development
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
... et al., 1989; Cserjesi and Olson, 1991). Whereas a single MEF2-binding site is transcriptionally inactive, when the ...
Gene Section ATF2 (activating transcription factor 2) Atlas of Genetics and Cytogenetics
... Following death receptor stimulation, there is phosphorylation and binding of ATF2/JUN to deathinducing ligands promoters (FASLG, TNF, TNFSF10), which allows the spread of death signals (Herr et al., 2000). Neuronal apoptosis requires the concomitant activation of ATF2/JUN and downregulation of FOS ...
... Following death receptor stimulation, there is phosphorylation and binding of ATF2/JUN to deathinducing ligands promoters (FASLG, TNF, TNFSF10), which allows the spread of death signals (Herr et al., 2000). Neuronal apoptosis requires the concomitant activation of ATF2/JUN and downregulation of FOS ...
hag expression in Bacillus subtilis is both negatively
... In Bacillus subtilis, the hag gene, which codes for flagellin, the structural protein of flagella, is transcribed by the sDdependent RNA polymerase (Mirel & Chamberlin, 1989; Ordal et al., 1993). This gene is transcribed as a monocistronic mRNA and shows a temporal pattern of expression that peaks a ...
... In Bacillus subtilis, the hag gene, which codes for flagellin, the structural protein of flagella, is transcribed by the sDdependent RNA polymerase (Mirel & Chamberlin, 1989; Ordal et al., 1993). This gene is transcribed as a monocistronic mRNA and shows a temporal pattern of expression that peaks a ...
The step-by-step evolution of vertebrate blood coagulation
... Genomic sequence data are making it possible to reconstruct the individual events that have led to the complex system of blood clotting observed in mammals. The raw material for all the many proteins involved in blood clotting was available in the form of domains in the common ancestor of vertebrate ...
... Genomic sequence data are making it possible to reconstruct the individual events that have led to the complex system of blood clotting observed in mammals. The raw material for all the many proteins involved in blood clotting was available in the form of domains in the common ancestor of vertebrate ...
The Role of Histone Modifications in Transcriptional Regulation upon Stress
... natural barrier for transcription; therefore the first thing RNA Pol II has to achieve is to gain access to DNA. At this stage histone modifying enzymes, chromatin remodeling complexes and chaperones play an essential role to regulate chromatin structure and allow accessibility to promoter regions ( ...
... natural barrier for transcription; therefore the first thing RNA Pol II has to achieve is to gain access to DNA. At this stage histone modifying enzymes, chromatin remodeling complexes and chaperones play an essential role to regulate chromatin structure and allow accessibility to promoter regions ( ...
The tightly regulated promoter of the xanA gene of
... we have shown that the one from Neurospora crassa fully complements a xanA deletion (Cultrone et al., 2005). In this article we investigate whether this gene is subject to the same regulatory signals as all other enzymes of the purine degradation pathway. We observed that the promoter element of xan ...
... we have shown that the one from Neurospora crassa fully complements a xanA deletion (Cultrone et al., 2005). In this article we investigate whether this gene is subject to the same regulatory signals as all other enzymes of the purine degradation pathway. We observed that the promoter element of xan ...
describe
... more pairs of unrelated, contrasting characteristics are crossed (e.g. tall plants with yellow pods × short plants with green pods), the different pairs of factors separate out independently of each other. That is, tall is not always inherited with yellow and short with green— some tall green offspr ...
... more pairs of unrelated, contrasting characteristics are crossed (e.g. tall plants with yellow pods × short plants with green pods), the different pairs of factors separate out independently of each other. That is, tall is not always inherited with yellow and short with green— some tall green offspr ...
6.1.1 Linking Mendel`s Findings to Modern Genetics
... more pairs of unrelated, contrasting characteristics are crossed (e.g. tall plants with yellow pods × short plants with green pods), the different pairs of factors separate out independently of each other. That is, tall is not always inherited with yellow and short with green— some tall green offspr ...
... more pairs of unrelated, contrasting characteristics are crossed (e.g. tall plants with yellow pods × short plants with green pods), the different pairs of factors separate out independently of each other. That is, tall is not always inherited with yellow and short with green— some tall green offspr ...
Genome-wide analysis of the distribution of AP2/ERF transcription
... cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbage and Arabidopsis; therefore, Arabidopsis is a viable reference species for comparative genomics studies. Transcr ...
... cabbage genome sequence and more than fifty thousand proteins have been obtained to date. However a high degree of sequence similarity and conserved genome structure remain between cabbage and Arabidopsis; therefore, Arabidopsis is a viable reference species for comparative genomics studies. Transcr ...
A rule-based kinetic model of RNA polymerase II C
... modelled as acting on Ser2P during elongation and on both Ser2P and Ser5P during recycling. The Ser2 kinase Bur1 is recruited to CTD repeats of elongating RNAPII phosphorylated on Ser5. Bur1 augments the major Ser2 kinase (Ctk1) and is capable of phosphorylating CTD repeats at Ser2, when Ctk1 is ...
... modelled as acting on Ser2P during elongation and on both Ser2P and Ser5P during recycling. The Ser2 kinase Bur1 is recruited to CTD repeats of elongating RNAPII phosphorylated on Ser5. Bur1 augments the major Ser2 kinase (Ctk1) and is capable of phosphorylating CTD repeats at Ser2, when Ctk1 is ...
Document
... plant growth and a better understanding of this process could lead to plants with more desirable economic traits, such as larger or more photosynthetic efficient leaves. Recently, much of the study of leaves has focused on understanding their polarity and formation from the meristem, with less atten ...
... plant growth and a better understanding of this process could lead to plants with more desirable economic traits, such as larger or more photosynthetic efficient leaves. Recently, much of the study of leaves has focused on understanding their polarity and formation from the meristem, with less atten ...
The Mycobacterium tuberculosis katG promoter region contains a
... Mycobacterium tuberculosis katG promoter. A 19 kb region immediately upstream of katG promoted expression of the luciferase gene in E. coli and Mycobacterium smegmatis . A smaller promoter fragment (559 bp) promoted expression with equal efficiency, and was used in all further studies. Two transcri ...
... Mycobacterium tuberculosis katG promoter. A 19 kb region immediately upstream of katG promoted expression of the luciferase gene in E. coli and Mycobacterium smegmatis . A smaller promoter fragment (559 bp) promoted expression with equal efficiency, and was used in all further studies. Two transcri ...
Gene Name
... in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a co ...
... in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a co ...
Pdf - Text of NPTEL IIT Video Lectures
... subunit of nucleic acid. So, it consist of nitrogen containing base 5 carbon sugar and phosphate groups. The sugar and phosphate molecules play crucial role in forming the linear D N A sequence or a structure. So, the three dimensional structure illustrate a very close connection between the molecul ...
... subunit of nucleic acid. So, it consist of nitrogen containing base 5 carbon sugar and phosphate groups. The sugar and phosphate molecules play crucial role in forming the linear D N A sequence or a structure. So, the three dimensional structure illustrate a very close connection between the molecul ...
Gene Section SRSF1 (serine/arginine rich splicing factor 1) -
... splicing depends on the pre-mRNA sequence and the cellular context. Cis-acting sequences and trans-acting factors modulate SF2/ASF activity. For example, SF2/ASF antagonizes the activity of hnRNP A/B proteins in splice site selection. An excess of hnRNP A1 favors distal 5' splice sites, whereas SF2/ ...
... splicing depends on the pre-mRNA sequence and the cellular context. Cis-acting sequences and trans-acting factors modulate SF2/ASF activity. For example, SF2/ASF antagonizes the activity of hnRNP A/B proteins in splice site selection. An excess of hnRNP A1 favors distal 5' splice sites, whereas SF2/ ...
HW4_final
... Make sure that you are using the “Single strand” mode for RNA sequences. Provide the motif logo. 2. What is the significance of the identified motif? Look at the occurrences distribution by clicking on “view occurrences distribution” or by downloading the motif occurrences file and explain how come ...
... Make sure that you are using the “Single strand” mode for RNA sequences. Provide the motif logo. 2. What is the significance of the identified motif? Look at the occurrences distribution by clicking on “view occurrences distribution” or by downloading the motif occurrences file and explain how come ...
as a PDF
... The B. subtilis trpEDCFBA operon contains six of the seven genes that are required for the biosynthesis of tryptophan from chorismic acid, the common aromatic amino acid precursor (Fig. 1). The trp operon is present within a histidine and aromatic amino acid supraoperon. In addition to the trp opero ...
... The B. subtilis trpEDCFBA operon contains six of the seven genes that are required for the biosynthesis of tryptophan from chorismic acid, the common aromatic amino acid precursor (Fig. 1). The trp operon is present within a histidine and aromatic amino acid supraoperon. In addition to the trp opero ...
Two Waves of Nuclear Factor κB Recruitment to Target Promoters
... quence of the NF-B site in MIP-2 (a gene with immediate NF-B recruitment) is identical to the sequence of one of the two NF-B sites in MCP-1 (a gene with delayed NF-B recruitment). Overall, this suggests that the observed differences in the kinetic of NF-B recruitment to the genes under investi ...
... quence of the NF-B site in MIP-2 (a gene with immediate NF-B recruitment) is identical to the sequence of one of the two NF-B sites in MCP-1 (a gene with delayed NF-B recruitment). Overall, this suggests that the observed differences in the kinetic of NF-B recruitment to the genes under investi ...
CHAPTER 7 TUNING THE DRAGON PROMOTER FINDER SYSTEM FOR HUMAN PROMOTER RECOGNITION
... signal thresholds are also used. These parameters have to be adjusted so that the tuned system achieves the desired performance. The tuning process is conducted 10 times for each selected level of sensitivity, and different models are produced in the process. Then, from all of the models, the select ...
... signal thresholds are also used. These parameters have to be adjusted so that the tuned system achieves the desired performance. The tuning process is conducted 10 times for each selected level of sensitivity, and different models are produced in the process. Then, from all of the models, the select ...
Expanded roles of leucine-responsive regulatory protein in
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
mMESSAGE mMACHINE® Kit User Guide
... mMESSAGE mMACHINE® Kits are designed for the in vitro synthesis of large amounts of capped RNA. Capped RNA mimics most eukaryotic mRNAs found in vivo, because it has a 7-methyl guanosine cap structure at the 5' end. mMESSAGE mMACHINE® Kit reactions include cap analog [m7G(5')ppp(5')G] in an ultra hi ...
... mMESSAGE mMACHINE® Kits are designed for the in vitro synthesis of large amounts of capped RNA. Capped RNA mimics most eukaryotic mRNAs found in vivo, because it has a 7-methyl guanosine cap structure at the 5' end. mMESSAGE mMACHINE® Kit reactions include cap analog [m7G(5')ppp(5')G] in an ultra hi ...
Transcriptional Attenuation
... termination is made conditional. We have divided them into four classes based on their common features. A single, well-studied example of each class is described in detail, and other examples are mentioned to illustrate unique points. Possible cases of attenuation in eukaryotes are described. We als ...
... termination is made conditional. We have divided them into four classes based on their common features. A single, well-studied example of each class is described in detail, and other examples are mentioned to illustrate unique points. Possible cases of attenuation in eukaryotes are described. We als ...
Write on zinc fingers
... The most straightforward method to generate new zinc finger arrays is to combine smaller zinc finger "modules" of known specificity. The structure of the zinc finger protein Zif268 bound to DNA described by Pavletich and Pabo in their 1991 publication has been key to much of this work and describes ...
... The most straightforward method to generate new zinc finger arrays is to combine smaller zinc finger "modules" of known specificity. The structure of the zinc finger protein Zif268 bound to DNA described by Pavletich and Pabo in their 1991 publication has been key to much of this work and describes ...
Transcription factor
In molecular biology and genetics, a transcription factor (sometimes called a sequence-specific DNA-binding factor) is a protein that binds to specific DNA sequences, thereby controlling the rate of transcription of genetic information from DNA to messenger RNA. Transcription factors perform this function alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription of genetic information from DNA to RNA) to specific genes.A defining feature of transcription factors is that they contain one or more DNA-binding domains (DBDs), which attach to specific sequences of DNA adjacent to the genes that they regulate. Additional proteins such as coactivators, chromatin remodelers, histone acetylases, deacetylases, kinases, and methylases, while also playing crucial roles in gene regulation, lack DNA-binding domains, and, therefore, are not classified as transcription factors.