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251 Lab 2 Chrisine
251 Lab 2 Chrisine

... Purpose: To search our sequence for the occurrence of any highly unusual repeat of a long word (> 3 nucleotides in length) The people who did the statistical analysis for the program BLAST (which we will begin using next week) said that it was below any reasonable level of statistical significance t ...
Tail DNA-Rapid Method - UMass Medical School
Tail DNA-Rapid Method - UMass Medical School

... When preparing samples of genomic DNA, use only those materials and solutions reserved for genomic use. These include Eppendorf tubes, proteinase K, dH2O, ethanol, and TE. When pipetting genomic DNA samples, only use pipette tips from which the tips have been snipped off (or purchased large-bore tip ...
Topic 7 The Discovery of DNA & Its Roles
Topic 7 The Discovery of DNA & Its Roles

... Studied the T2 bacteriophage that infects E. coli  T2 is a virus comprised of DNA & protein  Infected E. coli produce new viruses; viral DNA OR protein is responsible 32P and protein with 35S  Separately radiolabelled each component; DNA with  Allowed infection to proceed, then blended & centrif ...
Chapter Fourteen ANSWERS TO REVIEW QUESTIONS All the
Chapter Fourteen ANSWERS TO REVIEW QUESTIONS All the

... 4. An allele frequency describes the proportion or percentage of a given allele in a population; phenotypic frequency, that of a particular phenotype; genotypic frequency the proportion or percentage of a particular genotype at a given locus. 5. Nonrandom mating, migration, genetic drift, mutation, ...
Slide 1
Slide 1

... Genetic map ...
1. Explain why researchers originally thought
1. Explain why researchers originally thought

... 1. What does primase synthesize? A primer 2. Okazaki fragments make up which replicating strand? lagging Telomeres are special nucleotide sequences 3. _____ found at the ends of eukaryotic chromosomal DNA molecules. 4. Which proteins make up almost half of chromatin? histones 5. The less compacted, ...
Here
Here

... the genetics of the crops we plant. Although this section of the course is largely about genetically modified organisms (what we commonly refer to as the acronym, GMOs), one cannot understand genetic modification without understanding other breeding techniques, including induced-mutations and tradit ...
BIO208 Bacterial Genetics Worksheet 1 1. . Fill in: Transformation
BIO208 Bacterial Genetics Worksheet 1 1. . Fill in: Transformation

... a. _____________________________ DNA that binds repressor to prevent transcription b. _____________________________ DNA that binds RNA polymerase c. _________________________ binds repressor to allow transcription to occur d. _____________________________ a structural gene of the operon e. _________ ...
DNA Replication
DNA Replication

... The process of making a copy of DNA is called DNA replication. The process can be broken down into three steps. Step 1: Before replication can begin, the double helix must unwind. This is accomplished by enzymes called DNA helicases, which open up the double helix by breaking the hydrogen bonds that ...
lecture 7 (BY 14)
lecture 7 (BY 14)

... 12.4 DNA Replication and Repair ...
Unit 5 : Cell Growth and Reproduction
Unit 5 : Cell Growth and Reproduction

... Ribosomes contain rRNA (ribosomal RNA) and protein. Steps to Translation: 1. mRNA attaches to a ribosome. 2. The ribosome reads the mRNA and tRNA (transfer RNA) will transfer the correct amino acid onto the chain to build a protein. • 3. The anticodon is the region on tRNA that is complementary to t ...
7.014 Problem Set 3 Solutions
7.014 Problem Set 3 Solutions

... iii. Model C: DNA is a double-stranded helix with sugar-phosphate backbones on the outside, and bases in the middle, where purines (A and G) pair with purines and pyrimidines (T and C) pair with pyrimidines. The strands are running anti-parallel to each other. This model should be rejected. This des ...
7.014 Problem Set 3 Solutions
7.014 Problem Set 3 Solutions

... iii. Model C: DNA is a double-stranded helix with sugar-phosphate backbones on the outside, and bases in the middle, where purines (A and G) pair with purines and pyrimidines (T and C) pair with pyrimidines. The strands are running anti-parallel to each other. This model should be rejected. This des ...
Conjugative plasmids are circular pieces of DNA that not only
Conjugative plasmids are circular pieces of DNA that not only

... Conjugative plasmids are circular pieces of DNA that not only replicate in host bacteria, but also encode machinery to transfer itself into bacteria that do not contain the plasmid. This process is termed conjugation. Nickase is an enzyme that initiates the transfer of the plasmid from “donor” bacte ...
Public data and tool repositories Section 2 Survey of
Public data and tool repositories Section 2 Survey of

... 1. Integrates feature identity information with whole genome view 2. Allows one to view and search an organism's complete genome 3. Displays chromosome maps 4. User can zoom into progressively greater levels of detail, down to the sequence data for a region of interest. 5. Focus more on individual s ...
File
File

... from replication fork b. Synthesized discontinuously in batches c. 5' 3' synthesis catalyzed by d. Segments called e. attaches fragment to lagging strand 7. Overall replication process is termed D. Stages of Replication in a Prokaryote 1. Initiation a. at an rich area within b. primed with replicati ...
Chapter 10 Nucleic Acids and Protein synthesis
Chapter 10 Nucleic Acids and Protein synthesis

... to form a strip of RNA. NOTE – Base pairing rules are the same as in DNA replication, EXCEPT URACIL REPLACES THYMINE!! Transcription continues until the RNA polymerase reaches a DNA region called the “TERMINATION SIGNAL” = specific sequence of nucleotides that marks the end of a gene or genes. NOTE ...
Sos response in E. coli
Sos response in E. coli

Vocabulary to Know
Vocabulary to Know

... c. Does this person have a genetic disorder? If so, which one. 6. How are kayotypes used by genetic counselors? 7. Siblings are given up for adoption at birth and raised separately from one another for twenty-five years. When they meet for the first time, they realize that although they share the so ...
DNA Workshop - Mrs. Sills` Science Site
DNA Workshop - Mrs. Sills` Science Site

... 6. Why does DNA replication occur? _________________________________________________ Please return to the original screen and click on “DNA Workshop Activity”. On the left of your screen click on “DNA Replication”. Click on “unzip the cell”. 7. Where does DNA replication occur? _____________________ ...
Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... The DNA sample is divided among four test tubes, each containing the unknown sequence, primers, normal nucleotides (A, C, T, and G), replication enzymes, and a small amount of one type of terminator nucleotide. Replication results in different-sized fragments of complimentary copies of the unknown D ...
HOW SAGE WORKS (Reference http://www
HOW SAGE WORKS (Reference http://www

Evidence of relationships between organisms
Evidence of relationships between organisms

... Students should understand the following: • Genetic comparisons can be made between different species by direct examination of their DNA or of the proteins encoded by this DNA. • Comparison of DNA base sequences is used to elucidate relationships between organisms. These comparisons have led to new ...
Finding genes
Finding genes

... tuberculosis PknB Ser/Thr protein kinase is . . . ELKL motif kinase 1. Query = the part of the PknB sequence that matches ELKL-1. Subject = ELKL-1. Expect = expectation value = the number of hits of this quality expected by chance in a database of this size (5e-24 = 5 x 10-24; is this a big number o ...
Assignment1 (50points)
Assignment1 (50points)

... Assignment1 (50points) The goals of this exercise: * To assess the significance of the similarity between sequences (alignment, P ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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