Keverne et al (2001)
... Keverne, 1994; Brown et al., 1996). These transcription factors (Fos proteins or estradiol and its receptor complex) then activate the protein synthesis cascades required for the expression of maternal behavior. A similar role may be played by Peg3, presumably encoding a transcription factor and hig ...
... Keverne, 1994; Brown et al., 1996). These transcription factors (Fos proteins or estradiol and its receptor complex) then activate the protein synthesis cascades required for the expression of maternal behavior. A similar role may be played by Peg3, presumably encoding a transcription factor and hig ...
Chapter 1. Fundamental Properties of Genes
... In 1902, Sutton and Boveri independently realized that the behavior of genes in Mendelian crosses mimics the movement of chromosomes during meiosis and fertilization. They surmised that the two alleles of each gene correlated with the homologous pair of chromosomes. The equal segregation of alleles ...
... In 1902, Sutton and Boveri independently realized that the behavior of genes in Mendelian crosses mimics the movement of chromosomes during meiosis and fertilization. They surmised that the two alleles of each gene correlated with the homologous pair of chromosomes. The equal segregation of alleles ...
heredity and variation
... like a society in which every member would be identical with every other and in which no change-social, political, economic-could take place. If this had been the case, no complex civilizations like those of the present ' could have arisen. Variation is a primary condition of progress. THE MECHANISM ...
... like a society in which every member would be identical with every other and in which no change-social, political, economic-could take place. If this had been the case, no complex civilizations like those of the present ' could have arisen. Variation is a primary condition of progress. THE MECHANISM ...
Confirmation of Prostate Cancer Susceptibility Genes Using High
... families who are found to carry true germline mutations, following characterization of the causative gene. Shortly after the mapping of HPC1, we described an analysis (49) of 49 high-risk prostate cancer families for linkage to 1q24– 25 with the use of 10 highly polymorphic markers spanning the prop ...
... families who are found to carry true germline mutations, following characterization of the causative gene. Shortly after the mapping of HPC1, we described an analysis (49) of 49 high-risk prostate cancer families for linkage to 1q24– 25 with the use of 10 highly polymorphic markers spanning the prop ...
Genomic rearrangements account for more than one
... patients B212 and B242 more than one aberrant PCR product was co-amplified together with the wild-type transcript (Fig. 3A); sequence analysis of the gel purified bands revealed transcripts missing those exons that showed hemizygosity in the MLPA analysis as well as transcripts that lacked exons oth ...
... patients B212 and B242 more than one aberrant PCR product was co-amplified together with the wild-type transcript (Fig. 3A); sequence analysis of the gel purified bands revealed transcripts missing those exons that showed hemizygosity in the MLPA analysis as well as transcripts that lacked exons oth ...
Endogenous Retroviral Elements in Human DNA1
... core consensus sequence present in a number of viral enhancers (29). Sequences with potential enhancer function, such as this common motif or direct repeats, two of which are also contained in the S71 LTR-like sequence, may enable human endogenous LTRs to influence the expression of adjacent cellula ...
... core consensus sequence present in a number of viral enhancers (29). Sequences with potential enhancer function, such as this common motif or direct repeats, two of which are also contained in the S71 LTR-like sequence, may enable human endogenous LTRs to influence the expression of adjacent cellula ...
Review Process - The EMBO Journal
... interactions among other insulator DNA-binding proteins. Its own binding to chromatin seems to be in some cases dependent on other insulator proteins and in other cases independent. In this work, the authors have asked if CP190 associates with proteins that might explain its chromatin binding behavi ...
... interactions among other insulator DNA-binding proteins. Its own binding to chromatin seems to be in some cases dependent on other insulator proteins and in other cases independent. In this work, the authors have asked if CP190 associates with proteins that might explain its chromatin binding behavi ...
Genetic Analysis of DNA Replication in Bacteria: DNAB mutants that suppress DNAC Mutations and DNAQ Mutations That Suppress DNAE Mutations in Salmonella typhimurium.
... Therefore, strain DB4673 [prepared by growth in X broth + 0.2% (w/v) maltose and 1 mM MgSO,] was infected with ARM325 at a multiplicity of approximately 100. After 15 min at 37“, 0.1 ml of infected cells was diluted into 2 ml of LB containing 0.05% galactose and lo’ P22intHTl2/4. Incubation was cont ...
... Therefore, strain DB4673 [prepared by growth in X broth + 0.2% (w/v) maltose and 1 mM MgSO,] was infected with ARM325 at a multiplicity of approximately 100. After 15 min at 37“, 0.1 ml of infected cells was diluted into 2 ml of LB containing 0.05% galactose and lo’ P22intHTl2/4. Incubation was cont ...
Molecular markers located on the DGAT1, CAST, and - Funpec-RP
... animals inheriting the major allele genotype. However, the opposite effect was observed for the significant SNP located in the CAST gene, where animals inheriting the major allele genotype had significantly longer periods of days-open than animals inheriting the heterozygous genotype. A similar effe ...
... animals inheriting the major allele genotype. However, the opposite effect was observed for the significant SNP located in the CAST gene, where animals inheriting the major allele genotype had significantly longer periods of days-open than animals inheriting the heterozygous genotype. A similar effe ...
Murine herpesvirus 68 is genetically related to the
... properties of a virus are ultimately determined by its genetic content, it follows that the members of any one subgroup will be genetically related. However, the limitations of using subjective biological criteria for the classification of herpesviruses are best illustrated by considering Marek's di ...
... properties of a virus are ultimately determined by its genetic content, it follows that the members of any one subgroup will be genetically related. However, the limitations of using subjective biological criteria for the classification of herpesviruses are best illustrated by considering Marek's di ...
Highly Specialized Highly Specialized
... Science Park. The company has been in operation for over 10 years and has been at the forefront of Diagnostic healthcare in the region. It was established to bring a paradigm shift in the diagnostic industry in the MENA region through adoption of innovative technologies and exceptional customer serv ...
... Science Park. The company has been in operation for over 10 years and has been at the forefront of Diagnostic healthcare in the region. It was established to bring a paradigm shift in the diagnostic industry in the MENA region through adoption of innovative technologies and exceptional customer serv ...
Homology - a persona..
... and getting agreement on which definitions are best. Here, I examine 15 terminological problems, all of which are current, and all of which relate to the usage of homology and its associated terms. I suggest a set of definitions that are intended to be totally consistent among themselves and also as ...
... and getting agreement on which definitions are best. Here, I examine 15 terminological problems, all of which are current, and all of which relate to the usage of homology and its associated terms. I suggest a set of definitions that are intended to be totally consistent among themselves and also as ...
A Novel Multigene Family May Encode Odorant Receptors: A
... cDNAs defines a new multigene family that shares sequence and structural properties with the seven transmembrane domain superfamily of neurotransmitter and hormone receptors. This novel family, however, exhibits features different from any other member of the receptor superfamily thus far identified ...
... cDNAs defines a new multigene family that shares sequence and structural properties with the seven transmembrane domain superfamily of neurotransmitter and hormone receptors. This novel family, however, exhibits features different from any other member of the receptor superfamily thus far identified ...
Does RAGE protect smokers from COPD? CORRESPONDENCE
... position 82 in the third exon encoding the sRAGE protein (a nonsynonymous change altering polarity at this position) and has been shown to be associated with both reduced serum sRAGE levels and increased sRAGE signalling compared with the more common C allele [1]. This change in sRAGE signalling aff ...
... position 82 in the third exon encoding the sRAGE protein (a nonsynonymous change altering polarity at this position) and has been shown to be associated with both reduced serum sRAGE levels and increased sRAGE signalling compared with the more common C allele [1]. This change in sRAGE signalling aff ...
Molecular function - SGD-Wiki - Saccharomyces Genome Database
... Basic org. (homepage, search, LSP) Tabs, access to detailed info (sequence, gene ontology, phenotype, interaction, expression and regulation) • Data analysis: GO tools, YeastMine basics and use-cases ...
... Basic org. (homepage, search, LSP) Tabs, access to detailed info (sequence, gene ontology, phenotype, interaction, expression and regulation) • Data analysis: GO tools, YeastMine basics and use-cases ...
Regional DNA Hypermethylation at D17S5
... Our present data for renal cancers, together with our previous studies of colon (2) and brain tumors (1), establish that D17S5 hy permethylation is tightly coupled to 17p deletions and p53 gene mu tations in human cancers. Our results in renal cancer strongly suggest that this hypermethylation prece ...
... Our present data for renal cancers, together with our previous studies of colon (2) and brain tumors (1), establish that D17S5 hy permethylation is tightly coupled to 17p deletions and p53 gene mu tations in human cancers. Our results in renal cancer strongly suggest that this hypermethylation prece ...
Section 4-5 Teacher Notes
... Chromosomal Mutations Chromosomal mutations involve changes in the number or structure of chromosomes. Chromosomal mutations include deletions, duplications, inversions, and translocations. ...
... Chromosomal Mutations Chromosomal mutations involve changes in the number or structure of chromosomes. Chromosomal mutations include deletions, duplications, inversions, and translocations. ...
Historical review: Deciphering the genetic code – a personal account
... contained in ribosomes because amino acids were known to be incorporated into protein on these organelles. I estimated it would take me two years to set up a cell-free system to determine whether RNA or DNA stimulated protein synthesis, which was a pretty accurate estimate. I knew this was a risky p ...
... contained in ribosomes because amino acids were known to be incorporated into protein on these organelles. I estimated it would take me two years to set up a cell-free system to determine whether RNA or DNA stimulated protein synthesis, which was a pretty accurate estimate. I knew this was a risky p ...
Alisch RS, Wang T, Chopra P, Visootsak J, Conneely KN, Warren ST . Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus. BMC Med Genet. 2013 Jan 29;14:18. doi: 10.1186/1471-2350-14-18.
... Figure 1 FXS-associated differentially methylated loci. (A) Modified Manhattan plot of FXS-associated methylation levels in the peripheral blood: loci are displayed with the –log10(P-value) generated by the linear mixed-effect model (y-axis). Horizontal lines reflect cutoffs for FDR <0.05 (blue line ...
... Figure 1 FXS-associated differentially methylated loci. (A) Modified Manhattan plot of FXS-associated methylation levels in the peripheral blood: loci are displayed with the –log10(P-value) generated by the linear mixed-effect model (y-axis). Horizontal lines reflect cutoffs for FDR <0.05 (blue line ...
reviews
... happen primarily at the level of gene regulation rather than protein function20,21. So, a likely way for sub-functionalization to occur is through complementary changes in regulatory elements, perhaps leading to two separate expression domains that together recapitulate the more complex single expre ...
... happen primarily at the level of gene regulation rather than protein function20,21. So, a likely way for sub-functionalization to occur is through complementary changes in regulatory elements, perhaps leading to two separate expression domains that together recapitulate the more complex single expre ...
(XX) express twice as many genes as males (XY)?
... chromosome. X chromosome have genes for many characters unrelated to sex, whereas the Y chromosome mainly encodes genes related to sex determination • Human sex-linked genes follow the same pattern of inheritance as Morgan’s white-eye locus in Drosophila. – Fathers pass sex-linked alleles to all the ...
... chromosome. X chromosome have genes for many characters unrelated to sex, whereas the Y chromosome mainly encodes genes related to sex determination • Human sex-linked genes follow the same pattern of inheritance as Morgan’s white-eye locus in Drosophila. – Fathers pass sex-linked alleles to all the ...
The daily rhythm of mice
... particular finding suggested that peripheral oscillators are directly involved in the control of rhythmic physiological processes (see below). In Mop3/Bmal1 knock out mice, the expression of the related Bmal2 gene was drastically down regulated [17,21]. A transgenic rescue of Bmal2 expression in Mop3 ...
... particular finding suggested that peripheral oscillators are directly involved in the control of rhythmic physiological processes (see below). In Mop3/Bmal1 knock out mice, the expression of the related Bmal2 gene was drastically down regulated [17,21]. A transgenic rescue of Bmal2 expression in Mop3 ...
Association of MMP-3 (-1612 5A/6A) polymorphism with knee
... The genetic etiology of OA is not entirely known. Previously, OA was recognized as a noninflammatory arthropathy. However, recent studies have shown that an inflammatory process plays a part in the pathogenesis of OA [2, 3]. Pro-inflammatory cytokines are implicated as potential mediators in the dis ...
... The genetic etiology of OA is not entirely known. Previously, OA was recognized as a noninflammatory arthropathy. However, recent studies have shown that an inflammatory process plays a part in the pathogenesis of OA [2, 3]. Pro-inflammatory cytokines are implicated as potential mediators in the dis ...