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Biogenesis and significance of lipofuscin in the equine thyroid gland
Biogenesis and significance of lipofuscin in the equine thyroid gland

... showed the same ultrastructure as in situ. The protein content ranged from 15% to 77% w/w (mean = 36%). In contrast, the amino acid composition was constant and similar to that of thyroglobulin. The most distinctive feature of lipofuscin protein was the presence of four proteins of 14-18 kDa. The ha ...
Tearing down barriers: understanding the
Tearing down barriers: understanding the

... flowering plants is still under debate (Mallet, 2007), although it can be predicted that autopolyploidy is the more frequent form of polyploidy because within-species mating is more frequent than interspecific mating (Hegarty and Hiscock, 2008). However, a strict classification proves to be complex, ...
Ingestion of bacterially expressed dsRNAs can produce specific and
Ingestion of bacterially expressed dsRNAs can produce specific and

... Fig. 1. Quanti®cation of dsRNA produced in different bacterial strains. Bacteria of the indicated genotypes were lysogenized with lDE3, transformed with plasmids designed to express unc-22 dsRNA, grown in liquid media, induced with IPTG, and processed for total nucleic acid (see Section 2). Followin ...
High Level Expression of C4-Specific NADP
High Level Expression of C4-Specific NADP

... The chloroplastic NADP-malic enzyme (NADP-ME) is a key enzyme of the C4 photosynthesis pathway in NADPME type C4 plants such as maize. To express the chloroplastic NADP-ME in leaves of a C3 plant, rice, full-length cDNAs encoding the rice C3-specific isoform and the maize C4-specific isoform of the ...
A. thaliana - UC Davis Plant Sciences
A. thaliana - UC Davis Plant Sciences

... Predicted conservation of overall structure among highly diverged SCR variants Generated structural models of several SCR variants  found to fit a similar fold recognition despite extreme sequence variance ...
Chapter 8: Chromosomes and Chromosomal Anomalies
Chapter 8: Chromosomes and Chromosomal Anomalies

... puffiness12 of the hands and feet, unusual shape and positioning of the ears, a broad chest with widely spaced nipples, and a thick, webbed neck. Like all chromosomal anomalies, Turner’s women are at risk for a variety of medical complications. The most notable of these is irregular development of t ...
ATM and Artemis promote homologous recombination of
ATM and Artemis promote homologous recombination of

PUNNETT SQUARE PROBLEMS (or how to do a cross): STEP 1
PUNNETT SQUARE PROBLEMS (or how to do a cross): STEP 1

... RrYY, or rrYy, etc. (dihybrid means you are working with 2 genes, represented by 2 different letters). So how do you find genotypes? Sometimes genotypes may be given to you. Other times you may have to figure them out based on descriptive terms, like: homozygous dominant = big-big homozygous recessi ...
COMPUTATIONAL BIOLOGY
COMPUTATIONAL BIOLOGY

GeNeViSTA Coffin Siris Syndrome: A Disorder of SWI/SNF Pathway
GeNeViSTA Coffin Siris Syndrome: A Disorder of SWI/SNF Pathway

... The SWI/SNF complex was rst discovered in the yeast, Saccharomyces cerevisiae and is named after yeast mating types switching ”SWI) and sucrose non-fermenting ”SNF). The SWI/SNF complex in yeast contains the ATPase Swi2/Snf2p, two actin-related proteins ”Arp7p and Arp9) and other subunits involved i ...
Protocadherin-1: epithelial barrier dysfunction in asthma and eczema Grissel Faura Tellez
Protocadherin-1: epithelial barrier dysfunction in asthma and eczema Grissel Faura Tellez

... of exon 1 were identified in bronchial epithelial cells [11], whereas skin epithelial expression of PCDH1 has not been extensively characterised to date. In 2009, PCDH1 was identified as a susceptibility gene for bronchial hyperresponsiveness (BHR) and asthma in children and adults. Subsequently, PC ...
Genetics - Muscular Dystrophy Canada
Genetics - Muscular Dystrophy Canada

... gene alone cannot provide sufficient amounts of fully functional (full-length exon 7-containing) SMN protein that is necessary to maintain survival of motor neurons. ...
MEIOSIS I
MEIOSIS I

...  Meiosis results in cells known as gametes having one set of chromosomes (N)  Fertilization is the union of gametes (the sperm and the egg)  The fertilized egg is called a zygote and has one set of chromosomes from each parent (2N)  The zygote produces somatic cells by mitosis and develops into ...
Phenylketonuria (PKU)
Phenylketonuria (PKU)

... Many people ask me, “How can you live with this… doesn’t it bother you?”. The answer to this question is simply: NO. I enjoy it, after all… I have been living with it all seventeen years of my life. I actually enjoy having this disorder. I have a gift that many people have discovered. I have the abi ...
LP 6 Chromosome abnormalities
LP 6 Chromosome abnormalities

... and other cells with a chromosomal change. Just as mosaic tiles on a floor have a mixture of patterns, someone who is mosaic for a chromosomal change will have a mixture of cells in their body The proportions of chromosomally changed and normal cells can be quite variable and may also vary between t ...
The ara Operon - University of Pennsylvania
The ara Operon - University of Pennsylvania

... absent, AraC is produced and gets attached to araC. In this way araC acts as its own regulator. In the absence of arabinose, binding of AraC to araC prevents the attachment of RNA polymerase (RNAp) to PBAD and thus none of the genes can be transcribed. However, when arabinose becomes available, it b ...
Ribosome Profiling
Ribosome Profiling

... becomes very clear that the mechanism of translational initiation is far more complex than that was previously thought. Dramatic increase in the number of non-AUG start or initiation at 5ʹ UTR sites are documented through RP experiments [12-14] and these non-AUG translational initiation mostly found ...
PDF
PDF

... negative feedback inhibition mediated by production of a functional protein. To investigate how expression of the var gene family is regulated, we have created transgenic lines of parasites in which expression of individual var loci can be manipulated. Here we show that no such negative feedback sys ...
The Genetics of SMA - Families of SMA Canada
The Genetics of SMA - Families of SMA Canada

... gene alone cannot provide sufficient amounts of fully functional (full-length exon 7-containing) SMN protein that is necessary to maintain survival of motor neurons. ...
Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).
Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).

... normal FMRP in fragile X patients could alter posttranscriptional regulation of specific cellular RNAs, thus accounting for the pleiotropic phenotype associated with the syndrome (Ashley et al., 1993b; Siomi et al., 1994). In favor of the loss-of-function hypothesis, the lone I304N missense mutation ...
The CHARGE Targeted Sequencing Study
The CHARGE Targeted Sequencing Study

... GWAS of proinsulin, an additional signal at the 11p11.2 locus was identified for rs10838687 (r2 with rs7944584=0.074 in HapMap 2 CEU [Utah residents with ancestry from northern and western Europe]), which is intronic in MADD and associated with a 0.08-mg/dL difference in levels of fasting proinsulin ...
Handouts BIO301-Essentials of Genetics Virtual University of Pakistan
Handouts BIO301-Essentials of Genetics Virtual University of Pakistan

...  Skin color pigmentation in humans is controlled by at least three separately inherited genes. Pigmentation in humans  Controlled by three genes. ...
B.Sc-Part-I(ZOOLOGY)
B.Sc-Part-I(ZOOLOGY)

... There will be three written papers and one practical examination. Question No. 1 in each class will be compulsory & comprehensive based on units I to IV and of short Answer type. This will carry 40% of total marks (i.e. 20 marks in I & II year and 30 marks in III year). There will be two questions f ...
- NDLScholarship
- NDLScholarship

... The isolation of the gene responsible for cystic fibrosis has opened up the reality of genetic screening. A simple test of a person's saliva, costing about the price of a newspaper, allows identification of carriers (people who have one healthy and one faulty copy of the gene)-though only with about ...
Expression of Allene Oxide Synthase Determines - Bio
Expression of Allene Oxide Synthase Determines - Bio

... HPL, another enzyme of the lipoxygenase pathway, uses the same substrate as AOS to produce the volatiles trans2-hexenal and cis-3-hexenal and the wound hormone traumatin. Treatment of tomato plants with products of HPL did not induce the expression of AOS (data not shown) or PIN II (Fig. 4a). When p ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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