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Blue eye color in humans may be caused by a perfectly associated
Blue eye color in humans may be caused by a perfectly associated

... quently, several other linkage and association studies conWrmed the locus and OCA2 as the major contributors to human eye color variation (Sturm et al. 2001; Zhu et al. 2004; Posthuma et al. 2006; Frudakis et al. 2003) and 74% of the variation was estimated to a QTL, linked to OCA2 (DuVy et al. 2007 ...
Human karyotype
Human karyotype

...  female has twice the genetic material than males for genes on the X chromosome  dosage compensation: adjust for levels of gene expression  in humans and many organisms dosage compensation occurs by X-inactivation  the X-chromosome inactivated in each cell is randomly chosen  can observe inacti ...
Slides: background and project plan
Slides: background and project plan

... • Each cell contains an identical copy of the whole genome - but utilizes only a subset of the genes to perform diverse, unique tasks • Most genes are highly regulated – their expression is limited to specific tissues, developmental stages, physiological condition • Main regulatory mechanism – trans ...
Improving Virus C type 4 Interferon using Bioinformatics Techniques
Improving Virus C type 4 Interferon using Bioinformatics Techniques

... genetic information carried by chromosomes is located. Each nucleotide is composed of three parts: (1) a nitrogenous base known as purine (adenine (A) and guanine (G)) or pyrimidine (cytosine (C) and thymine (T)); (2) a sugar, deoxyribose; and (3) a phosphate group. The actual work of translating th ...
An Investigation of Codon Usage Bias Including
An Investigation of Codon Usage Bias Including

... amino acids. This means that multiple codons sometimes code for the same amino acid (degeneracy). It has long been known that organisms preferentially utilize one or more of these synonymous codons in their coding sequences [6, 7, 9, 15]. This bias in codon usage can be exploited to predict such thi ...
The Two Faces of Higher Eukaryotic DNA Replication Origins
The Two Faces of Higher Eukaryotic DNA Replication Origins

... the minibubbles must span the origin of bidirectional replication. The second observation possibly inconsistent with the model is that the shortest nascent leading strands appear to become progressively longer at increasing distances from the origin of bidirectional replication (Vassilev et al., 199 ...
New proposals for partial antibody deficiencies
New proposals for partial antibody deficiencies

... •This is a diagnosis of exclusion of other known primary antibody deficiencies. There are several different clinical phenotypes, probably representing distinguishable diseases with differing immunopathogeneses.It is not clear currently whether the mutations associated with some of these patients inv ...
Exporter la page en pdf
Exporter la page en pdf

... firings rather than by the velocity of single forks. Activation of internal origins in a specific temporal transition region is directly demonstrated by DNA combing of the IGH locus in HeLa cells. Analysis of published origin maps in HeLa cells and published replication timing and DNA combing data in ...
Discriminative and informative features for biomolecular text mining
Discriminative and informative features for biomolecular text mining

... classification by using multiple weak feature selectors to build a single robust one. These weak feature selectors are created by bootstrapping the training data and then building an SVM. The weights of the support vectors determine the rank of the features, and individual rankings are aggregated in ...
GHS-Express database http://genecanvas.ecgene.net/uploads/Fo
GHS-Express database http://genecanvas.ecgene.net/uploads/Fo

... expressions with a p-value < 10-5 are reported (n=225615) together with the position of the SNP and of the associated gene. “cistransDistance” is 109 when the SNP and gene are ...
MHC Recognition MHC Recognition DuPont Essay Rough Draft
MHC Recognition MHC Recognition DuPont Essay Rough Draft

... relationships. The female partners that nest together share the allelic forms of MHC. Their genotypes, the genes, and haplotypes, a group of alleles of different genes that are closely placed together and therefore tend to be inherited together, affect the process What are alleles?. They play roles ...
PDF - Hormones.gr
PDF - Hormones.gr

... regulate gene expression, independently of DNA binding, by physically interacting with other transcription factors (NF-κΒ, AP-1 or STAT5). Moreover, the hGR was recently shown to undergo acetylation by the transcription factor CLOCK in a lysine cluster of its hinge region. This CLOCK-mediated post-t ...


... Can short daily loading episodes improve tendon healing? ...
unit-2 genetics of prokaryotes and eukaryotic
unit-2 genetics of prokaryotes and eukaryotic

... region of sequence homology to form a tiny heteroduplex joint at the point of union (Figure 2.5). The integrase resembles a DNA topoisomerase in that it forms a reversible covalent linkage to DNA wherever it breaks a DNA chain. The same type of site-specific recombination mechanism can also be carri ...
The DUET gene is necessary for chromosome
The DUET gene is necessary for chromosome

... (Siddiqi et al., 2000). A 1.26 kb coding region of DUET cDNA lacking the PHD-finger domain was amplified using the primers STMF1 (5′-GGTCATTTGGTATGTGTCAATGGTATGG-3′) and STMR3 (5′-TCAATCTCAGTCACTACAAAATTTGACAAG-3′) and subcloned into pGEM-T (Promega) for synthesis of RNA probes. Molecular analysis o ...
Genome-Wide Analysis of In Vivo Binding of the Master Regulator
Genome-Wide Analysis of In Vivo Binding of the Master Regulator

... least, activated by a pathway-specific regulator within or adjacent to the cluster, and in a growth-phase dependent manner [7]. A pivotal question to address is how primary environmental signals are relayed to global carbon and nitrogen control and further to the control of development and antibioti ...
mart
mart

... is a non-redundant set of transcripts and proteins of known genes for many species, including human, mouse and rat. • Enzyme Commission (EC) numbers are assigned to different enzymes and linked to genes through EntrezGene. ...
introduction
introduction

... apicomplexans the COXII is nuclear-encoded (Gardner et al., 2002). However, in other organisms, with the exception of certain green algae and leguminous plants, it is encoded by the mitochondrial genome (Gray, 1999; Palmer et al., 2000). The COXII protein of apicomplexan parasites contains two polyp ...
- Zurich Open Repository and Archive
- Zurich Open Repository and Archive

... specifically interact with LHCII subunits (Park et al., 2007). This together with the retention of these proteins in the mutants, suggested that SGR might be involved in dismantling chl-protein complexes as a prerequisite for both chl and apoprotein degradation. The aim of this study was to thorough ...


... Cg-14, was expressed in C. magna isolate L-2.5, a pathogen of cucurbits that causes minor symptoms in watermelon seedlings and avocado fruits. Isolate L-2.5 was transformed with pPCPH-1 containing hph-B as a selectable marker and the 4.1-kb genomic pel clone. Southern hybridization, with the 4.1-kb ...
Genotype–phenotype correlations in laminopathies
Genotype–phenotype correlations in laminopathies

Structure, expression differentiation and evolution of duplicated fiber
Structure, expression differentiation and evolution of duplicated fiber

... G. hirsutum while simultaneously maintaining its high fiber yield [4]. The cotton fiber is a single cell without the complex cell division and multicellular development that develops from ovule’s epidermal cells. Fiber development occurs in four distinct, but overlapping stages: initiation, elongati ...
Plant LTR-retrotransposons and MITEs: control of
Plant LTR-retrotransposons and MITEs: control of

... 4 –8% of the genome, in large genomes like maize they can account for more than 50– 80% of their DNA content (Kumar and Bennetzen, 1999). The copy number of retrotransposons increases with their activity due to their replicative mechanism of transposition and has probably played a major role in plan ...
Unit 30C Cell Division, Genetics, and Molecular
Unit 30C Cell Division, Genetics, and Molecular

... division. Organisms that reproduce asexually produce offspring that are identical to the parents. Sexually reproducing organisms exchange genetic information, so that the offspring have a unique combination of traits. The genetic material determines the proteins that make up cells, which ultimately ...
The Role of H2A.Z in Chromosome Segregation in
The Role of H2A.Z in Chromosome Segregation in

... H2A.Z and the subunits of the SWR1 and NuA4 complexes have been independently linked to kinetochore components and are important for chromosome stability. It has also been found that they all have synthetic interactions with both kinetochore and mitotic spindle mutants (Krogan et al., 2004). Additio ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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