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Questions Methods Evaluation Answers Can short daily loading episodes improve tendon healing? Yes II Has loading different impact on early and late healing? No III Does unloading influence ECM, inflammation and tendon genes during tendon healing? Yes IV Is the BMPsystem regulated during tendon healing? Yes By unloading? No Can myostatin stimulate tendon repair? Yes V Is it regulated by unloading? VI How long does the gene expression response last after loading? Yes Gone by 24h. Linköping 2011 Linköping University Faculty of Health Sciences Department of clinical and experimental medicine Division of Orthopaedics Response to mechanical loading in healing tendons I Pernilla Eliasson Thesis at a glance: Linköping University Medical Dissertations No. 1247 Response to mechanical loading in healing tendons Pernilla Eliasson Questions Methods Evaluation Answers Can short daily loading episodes improve tendon healing? Yes II Has loading different impact on early and late healing? No III Does unloading influence ECM, inflammation and tendon genes during tendon healing? Yes IV Is the BMPsystem regulated during tendon healing? Yes By unloading? No Can myostatin stimulate tendon repair? Yes V Is it regulated by unloading? VI How long does the gene expression response last after loading? Yes Gone by 24h. Linköping 2011 Linköping University Faculty of Health Sciences Department of clinical and experimental medicine Division of Orthopaedics Response to mechanical loading in healing tendons I Pernilla Eliasson Thesis at a glance: Linköping University Medical Dissertations No. 1247 Response to mechanical loading in healing tendons Pernilla Eliasson
