Two-Exon Skipping Due to a Point Mutation in p67
... proline-rich sequence and the mutant protein may have lost its stability due to a loss of these sequences. The sequences, therefore, contributetoprotein stabilitythrough intra-or intermolecular association of p67-phox with itself or with other proteins such as p47-phox or p40-phox that contain simil ...
... proline-rich sequence and the mutant protein may have lost its stability due to a loss of these sequences. The sequences, therefore, contributetoprotein stabilitythrough intra-or intermolecular association of p67-phox with itself or with other proteins such as p47-phox or p40-phox that contain simil ...
Microbial Genetics - MyCourses
... Repressor inactive, operon on. When the inducer allolactose binds to the repressor protein, the inactivated repressor can no longer block transcription. The structural genes are transcribed, ultimately resulting in the production of the enzymes needed for lactose catabolism. © 2016 Pearson Education ...
... Repressor inactive, operon on. When the inducer allolactose binds to the repressor protein, the inactivated repressor can no longer block transcription. The structural genes are transcribed, ultimately resulting in the production of the enzymes needed for lactose catabolism. © 2016 Pearson Education ...
Regulation of Ovule Development
... In addition, ANT is likely to play a larger role in medial domain development, as shown by double mutant analysis with LEUNIG (LUG), a putative transcriptional corepressor (Conner and Liu, 2000). lug and ant mutants both have weak effects on marginal tissue formation, but double mutants show a stron ...
... In addition, ANT is likely to play a larger role in medial domain development, as shown by double mutant analysis with LEUNIG (LUG), a putative transcriptional corepressor (Conner and Liu, 2000). lug and ant mutants both have weak effects on marginal tissue formation, but double mutants show a stron ...
Glutathione production by efficient ATP
... We reported the cellular ATP synthetic activities of 3960 single-gene deletion E. coli strains in a previous paper (Hara et al., 2009). Twenty-one strains showed 4 200% higher cellular ATP synthetic activities compared with the parental strain (BW25113). However, most of them (18) also showed less c ...
... We reported the cellular ATP synthetic activities of 3960 single-gene deletion E. coli strains in a previous paper (Hara et al., 2009). Twenty-one strains showed 4 200% higher cellular ATP synthetic activities compared with the parental strain (BW25113). However, most of them (18) also showed less c ...
Analyzing the Paper
... After baseline testing on the 49ΊC tail-withdrawal test, all mice received a s.c. injection of MK-801 (0.075 mg/kg) or saline (10 ml/kg), followed immediately by an i.p. injection of U50,488 (50 mg/kg). Percent analgesia scores were calculated as described. *, Significant blockade of analgesia by MK ...
... After baseline testing on the 49ΊC tail-withdrawal test, all mice received a s.c. injection of MK-801 (0.075 mg/kg) or saline (10 ml/kg), followed immediately by an i.p. injection of U50,488 (50 mg/kg). Percent analgesia scores were calculated as described. *, Significant blockade of analgesia by MK ...
PDF
... of at least nine were chosen for further analysis. RNA sequencing was carried out at the Institute of Applied Genomics (IGA, Udine, Italy) on an Illumina Genome Analyzer, Hi-Seq2000, performing 100 bp-paired end sequencing in a single lane according to the manufacturer’s instructions. The sequenced ...
... of at least nine were chosen for further analysis. RNA sequencing was carried out at the Institute of Applied Genomics (IGA, Udine, Italy) on an Illumina Genome Analyzer, Hi-Seq2000, performing 100 bp-paired end sequencing in a single lane according to the manufacturer’s instructions. The sequenced ...
Document
... A callosity is more diffuse type of thickening of the keratin layer which seems to be a protective response to widely applied repeated friction or pressure. Calluses (keratotic plaques), are often occupational ,for example they are seen on the hands of manual workers . Corns ( keratotic papules) , o ...
... A callosity is more diffuse type of thickening of the keratin layer which seems to be a protective response to widely applied repeated friction or pressure. Calluses (keratotic plaques), are often occupational ,for example they are seen on the hands of manual workers . Corns ( keratotic papules) , o ...
EFFECT OF FSH β-SUB UNIT AND FSHR GENES
... interaction genes were analyzed. There is no significant effect of interaction genes in observed parameter (data are not shown). Significant effect was found only at ovulation rate in FSHR gene of all breed without being grouped (Table 3). Individual animal with CC genotype of FSHR| AluI has higher ...
... interaction genes were analyzed. There is no significant effect of interaction genes in observed parameter (data are not shown). Significant effect was found only at ovulation rate in FSHR gene of all breed without being grouped (Table 3). Individual animal with CC genotype of FSHR| AluI has higher ...
Global analysis of correlated gene expression across the
... coded strip on the left, using the exact colors from the Allen Reference Atlas. Displayed in this way, large spans of “red/orange” blocks are observed along the diagonal corresponding to high correlations between voxels within a given structure. Hierarchical Clustering Based on Correlations between ...
... coded strip on the left, using the exact colors from the Allen Reference Atlas. Displayed in this way, large spans of “red/orange” blocks are observed along the diagonal corresponding to high correlations between voxels within a given structure. Hierarchical Clustering Based on Correlations between ...
Athymic Nude Mice
... increases with age, but that the differentiation into Thy-1 bearing cells can be triggered by extreme environmental conditions such as infections and hormonal manipulations (Scheid et al, 1975). Although the athymic nude mouse is grossly deficient in peripheral T-cell(s), the number of lymphocytes b ...
... increases with age, but that the differentiation into Thy-1 bearing cells can be triggered by extreme environmental conditions such as infections and hormonal manipulations (Scheid et al, 1975). Although the athymic nude mouse is grossly deficient in peripheral T-cell(s), the number of lymphocytes b ...
Role of Che Y Protein in the Bacterial Chemosensory Information
... indicating a central role of Che Y in the sensory information pathway. Second site suppressors of Che Y isolated in Fla A locus indicating suggest some type of interaction between Che Y and the flagellar machinery. Che Y overexpression studies in strains deleted for Che A, Che B, Che W, Che R, Che Y ...
... indicating a central role of Che Y in the sensory information pathway. Second site suppressors of Che Y isolated in Fla A locus indicating suggest some type of interaction between Che Y and the flagellar machinery. Che Y overexpression studies in strains deleted for Che A, Che B, Che W, Che R, Che Y ...
Epigenetic Mechanisms of Gene Regulation
... associated with transcriptional regulation and higher order chromatin structure. In mammals, DNA methylation patterns are not randomly distributed throughout the genome, but rather methylated DNA is localized to discrete regions of the genome enriched in repetitive DNA and transposable elements, imp ...
... associated with transcriptional regulation and higher order chromatin structure. In mammals, DNA methylation patterns are not randomly distributed throughout the genome, but rather methylated DNA is localized to discrete regions of the genome enriched in repetitive DNA and transposable elements, imp ...
Review #3 - California Lutheran University
... the human β–interferon gene? What is combinatorial control? How does that help explain how we can individually turn on genes? How does mating type switching occur in yeast? Which experiments could be performed to show how this system works? What are the major ways that transcriptional repressors tur ...
... the human β–interferon gene? What is combinatorial control? How does that help explain how we can individually turn on genes? How does mating type switching occur in yeast? Which experiments could be performed to show how this system works? What are the major ways that transcriptional repressors tur ...
Folic Acid (Folacin) – New Application of a Cosmetic Ingredient
... Introduction Vitamins have been known to play an important role in human life. They must be supplied in the diet or in dietary supplements because they are necessary for our growth, vitality, and general well-being. Many of them, including folic acid, are not produced in human organism. Vitamins hel ...
... Introduction Vitamins have been known to play an important role in human life. They must be supplied in the diet or in dietary supplements because they are necessary for our growth, vitality, and general well-being. Many of them, including folic acid, are not produced in human organism. Vitamins hel ...
Fungi use the SakA (HogA) pathway for phytochrome
... ccgA 11,12, was quantified by real time polymerase chain reaction (RT-qPCR). The values were normalized to the constitutive H2B (histone) gene. In seven strains both genes were not light-inducible, whereas in mutant M17-3 light induction was not affected. Thus seven blind mutant strains were isolated ...
... ccgA 11,12, was quantified by real time polymerase chain reaction (RT-qPCR). The values were normalized to the constitutive H2B (histone) gene. In seven strains both genes were not light-inducible, whereas in mutant M17-3 light induction was not affected. Thus seven blind mutant strains were isolated ...
Supplemental Results Spatial dispersion often indicates
... within 9 Å of the predicted DNA-binding interface (Figure S11b). Replacement of the large volume of the phenylalanine side chain with the smaller volume of isoleucine could alter the geometry of the DNA-binding cavity sufficiently to disrupt that interaction. Notably, while F559 is in the second she ...
... within 9 Å of the predicted DNA-binding interface (Figure S11b). Replacement of the large volume of the phenylalanine side chain with the smaller volume of isoleucine could alter the geometry of the DNA-binding cavity sufficiently to disrupt that interaction. Notably, while F559 is in the second she ...
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... npc2-like genes in Drosophila melanogaster The Npc2 protein has been conserved throughout much of eukaryotic evolution. Only one npc2 gene is present in yeast, worm, mouse and human genomes. Drosophila melanogaster, clearly a highly advanced organism, has a family of eight npc2-like genes, which we ...
... npc2-like genes in Drosophila melanogaster The Npc2 protein has been conserved throughout much of eukaryotic evolution. Only one npc2 gene is present in yeast, worm, mouse and human genomes. Drosophila melanogaster, clearly a highly advanced organism, has a family of eight npc2-like genes, which we ...
Chapter 1 - Online Open Genetics
... Sometimes a letter is used as the name of a gene, and superscripts can modify it to indicate the different alleles (Figure 1-6). One common single letter code for an allelic series is “I”. Red blood cells can have their cell membranes modified by sugar tags that give rise to our blood type. One alle ...
... Sometimes a letter is used as the name of a gene, and superscripts can modify it to indicate the different alleles (Figure 1-6). One common single letter code for an allelic series is “I”. Red blood cells can have their cell membranes modified by sugar tags that give rise to our blood type. One alle ...
Using Transgenic Technology to Characterize Regulatory Regions
... e.g., knockout of HoxB4 produces a partial homeotic transformation of second cervical vertebra from axis to atlas Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
... e.g., knockout of HoxB4 produces a partial homeotic transformation of second cervical vertebra from axis to atlas Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
Modulation of base excision repair of 8
... 8-oxoG in the 50 -UTR of the gene documented a clear decrease of fluorescence, compared with cells transfected with the reference plasmids harbouring the unmodified oligonucleotide (Figure 1B–F). The effect had the same magnitude for 8-oxoG located in the transcribed DNA strand and one in the compleme ...
... 8-oxoG in the 50 -UTR of the gene documented a clear decrease of fluorescence, compared with cells transfected with the reference plasmids harbouring the unmodified oligonucleotide (Figure 1B–F). The effect had the same magnitude for 8-oxoG located in the transcribed DNA strand and one in the compleme ...
PHANTASTICA Regulates Development of the Adaxial Mesophyll in
... radialization, but a common conclusion nonetheless was a role for PHAN orthologs in negative regulation of class I KNOX genes. The leaf phenotypes of the rs2 mutant in maize and the as1 mutant in Arabidopsis in fact have a striking resemblance to those resulting from KNOX overexpression in those spe ...
... radialization, but a common conclusion nonetheless was a role for PHAN orthologs in negative regulation of class I KNOX genes. The leaf phenotypes of the rs2 mutant in maize and the as1 mutant in Arabidopsis in fact have a striking resemblance to those resulting from KNOX overexpression in those spe ...
assembling the aging puzzle - Biomedical Computation Review
... his recent work on the transcriptional profile: a snapshot of the genes being expressed in a group of cells at any one time, usually obtained with microarray technology. Since a transcriptional profile is a “fairly complex readout from hundreds and hundreds of different markers,” Kim says, it provid ...
... his recent work on the transcriptional profile: a snapshot of the genes being expressed in a group of cells at any one time, usually obtained with microarray technology. Since a transcriptional profile is a “fairly complex readout from hundreds and hundreds of different markers,” Kim says, it provid ...
Blue eye color in humans may be caused by a perfectly associated
... quently, several other linkage and association studies conWrmed the locus and OCA2 as the major contributors to human eye color variation (Sturm et al. 2001; Zhu et al. 2004; Posthuma et al. 2006; Frudakis et al. 2003) and 74% of the variation was estimated to a QTL, linked to OCA2 (DuVy et al. 2007 ...
... quently, several other linkage and association studies conWrmed the locus and OCA2 as the major contributors to human eye color variation (Sturm et al. 2001; Zhu et al. 2004; Posthuma et al. 2006; Frudakis et al. 2003) and 74% of the variation was estimated to a QTL, linked to OCA2 (DuVy et al. 2007 ...
High-efficiency Agrobacterium-mediated transformation of chickpea
... system of chickpea (Cicer arietinum L.), callus derived from mature embryonic axes of variety P-362 was transformed with Agrobacterium tumefaciens strain LBA4404 harboring p35SGUS-INT plasmid containing the uidA gene encoding b-glucuronidase (GUS) and the nptII gene for kanamycin selection. Various ...
... system of chickpea (Cicer arietinum L.), callus derived from mature embryonic axes of variety P-362 was transformed with Agrobacterium tumefaciens strain LBA4404 harboring p35SGUS-INT plasmid containing the uidA gene encoding b-glucuronidase (GUS) and the nptII gene for kanamycin selection. Various ...
Germline Selection: Population Genetic Aspects of the
... tissue andthe potentialfor somatic mutation and selection is more obvious (Buss 1983; SLATKIN1985). T h e model developed here is equally applicable to both systems as it makes no distinction between mutations accumulating during mitosis in a specialized germline and those accumulating in a totipote ...
... tissue andthe potentialfor somatic mutation and selection is more obvious (Buss 1983; SLATKIN1985). T h e model developed here is equally applicable to both systems as it makes no distinction between mutations accumulating during mitosis in a specialized germline and those accumulating in a totipote ...