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... Biologists often get a piece of DNA sequence and want to know what's in it. One of the most obvious questions to ask is, does it contain a gene? Because genomes of organisms consist of many non-coding regions, it's not clear that a random piece of DNA will always have a gene. And if there is a gene, ...
Biol115 The Thread of Life
Biol115 The Thread of Life

... 3. Include the following terms in a description of transcription: mRNA, RNA polymerase, the promoter, the terminator, the transcription unit, initiation, elongation, termination, splicing and introns. 4. Explain three types of post-transcriptional processing of eukaryotic pre-mRNA. 5. Suggest reason ...
DNA  RNA  Proteins - Aurora City School
DNA RNA Proteins - Aurora City School

... binds to the specific codon, called the start codon, where translation begins on mRNA.  Initiator tRNA carries the amino acid Methionine (Met); its anticodon UAC binds to the start codon, AUG  2.A large ribosomal subunit binds to the smaller one, creating a function ribosome. The initiator tRNA fi ...
Exam IV 1710_1711 F'01.doc
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... Although protein synthesis in eukaryotic and prokaryotic cells is generally similar, the subtle differences are often utilized to specifically target many common antibiotics against prokaryotes. ...
Unit 4
Unit 4

... Nucleic acids have specific sequences of monomers that are like bits of information – much like the letters of the alphabet. In DNA or RNA, the monomers are the four types of nucleotides, which differ in their nitrogenous bases. Genes are hundreds of thousands of nucleotides long – each gene with a ...
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A change that makes a polypeptide defective has been discovered

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... An interesting task is to imagine that life in another solar system has the same code but that it is overlapping. Compare the polypeptides made from identical base sequences with a non-overlapping code and an overlapping code. One exam board has asked a question on this theme. ...
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... C30. A disadvantage of mRNAs with a short half-life is that the cells probably waste a lot of energy making them. If a cell needs the protein encoded by a short-lived mRNA, the cell has to keep transcribing the gene that encodes the mRNA because the mRNAs are quickly degraded. An advantage of short- ...
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投影片 1
投影片 1

... For eucaryotes, newly transcribed RNA( primary RNA), inside the nucleus, needs to take some processes of modification before entering the cytoplasm. Capping at 5’ end with a methyl G. Splicing and remove introns( non-coding sequences). Polyadenylation at 3’end.( poly-A tail) ...
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Chemical basis of Inheritance Review KEY - Pelletier Pages

... 13. What role do DNA polymerase and DNA ligase play in gene replication? DNA polymerase adds DNA nucleotides to the 3’ end of the growing DNA molecule. DNA ligase forms the phosphodiester bonds between the okazaki fragments on the lagging strand. 14. What two bases can pair with adenine? T and U 15. ...
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No Slide Title

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Chapter 17: From Gene to Protein
Chapter 17: From Gene to Protein

... 13. Explain the significance of the reading frame during translation. 14. Explain the evolutionary significance of a nearly universal genetic code. The Synthesis and Processing of RNA 15. Explain how RNA polymerase recognizes where transcription should begin. Describe the promoter, the terminator, a ...
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... • Mitochondrial and chloroplast ribosomes are quite similar to prokaryotic ribosomes, reflecting their supposed prokaryotic origin • Cytoplasmic ribosomes are larger and more complex, but many of the structural and functional properties are similar • 40S subunit contains 30 proteins and 18S RNA. • 6 ...
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... RNA is to deliver amino acids one by one to protein chains growing at ribosomes. ...
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...  Must be accurate or the reading frame will be inaccurate  This complex then binds to mRNA at the beginning of the gene  2 ribosomal subunits recognize the 5’ cap ...
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... DNA double helix unzips as hydrogen bonds between complementary bases break and the two polynucleotide strands separate ...
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Gene, Protein Synthesis & Gene Regulation

... i- Silent mutation: i.e. the codon containg the changed base may code for the same amino acid. For example, in serine codon UCA, if A is changed to U giving the codon UCU, it still code for serine. See table. ii- Missense mutation: the codon containing the changed base may code for a different amino ...
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...  Protein: chain of amino acids  Triplets of nucleotides specify each amino acid  Each nucleotide triplet is called a codon  Genetic code: table that gives the correspondence between each possible triplet and each amino acid ...
Central Dogma Activity Worksheet
Central Dogma Activity Worksheet

... construct a house, the DNA "blueprint" tells the cell how to build the organism. Yet, how can a heart be so different from a brain if all the cells contain the same instructions? A cell has the ability to turn off most genes and only work with the genes necessary to do a job. Remember, a gene is sec ...
BIOLOGY CONTENT STANDARDS REVIEW
BIOLOGY CONTENT STANDARDS REVIEW

... The structures and functions of DNA, RNA, and protein are distinct and fundamental to Biology. 16. Draw and label a DNA molecule with nine base pairs, the transcribed mRNA molecule, and the resulting protein molecule. 17. Describe the three main types of RNA. Where is each found in the cell? Draw a ...
RNA and Protein Synthesis
RNA and Protein Synthesis

... The mRNA strand detaches from the DNA once the gene is transcribed. It will leave the nucleus to find a ribosome floating in the cytoplasm or find a ribosome on the Rough ER. This event marks the end of Transcription and the beginning of Translation. ...
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Messenger RNA



Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression. Following transcription of primary transcript mRNA (known as pre-mRNA) by RNA polymerase, processed, mature mRNA is translated into a polymer of amino acids: a protein, as summarized in the central dogma of molecular biology.As in DNA, mRNA genetic information is in the sequence of nucleotides, which are arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons, which terminate protein synthesis. This process of translation of codons into amino acids requires two other types of RNA: Transfer RNA (tRNA), that mediates recognition of the codon and provides the corresponding amino acid, and ribosomal RNA (rRNA), that is the central component of the ribosome's protein-manufacturing machinery.The existence of mRNA was first suggested by Jacques Monod and François Jacob, and subsequently discovered by Jacob, Sydney Brenner and Matthew Meselson at the California Institute of Technology in 1961.
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