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Transposable elements in Escherichia coli antimicrobial resistance
Transposable elements in Escherichia coli antimicrobial resistance

... or transcriptionally repressed regions, that help them survive for longer periods [5]. Several types of transposable elements are present. One of those is mobile genetic elements which includes two classes based on their mechanism of transposition, and can best be described as either “copy and paste ...
Delivering copper within plant cells Edward Himelblau* and
Delivering copper within plant cells Edward Himelblau* and

... sequence of RAN1 revealed that it is the Arabidopsis CCC2/MNK homolog, and it has been shown that RAN1 can rescue ccc2 mutant yeast [3••]. The metal-binding, membrane-spanning and ATPase domains of RAN1 are similar to those of CCC2/MNK, yet both RAN1 and CCC2 do not appear to have an important targe ...
Increased Expression of c-jun, junB, AP
Increased Expression of c-jun, junB, AP

... were collected, aliquoted in small volumes, and frozen at - 135°C until used. The protein content was measured as described by Bradford (1976) and diluted to the same concentration. We used whole-cell extracts in this experiment for two reasons. First, the association of Fos and Jun proteins occurs ...
Epigenetic and genetic factors affect transgene
Epigenetic and genetic factors affect transgene

... The cw-acting element that operates within this system must logically be due to either the transgene itself or its integration site. One must presume that integration site has some effect because different lines that carry the same transgene may behave differently, with respect to whether a gamete o ...
Involvement of Sox1, 2 and 3 in the early and subsequent molecular
Involvement of Sox1, 2 and 3 in the early and subsequent molecular

... 2522 Y. Kamachi and others hours). Because of this early response, we have anticipated that the mechanism of δ1-crystallin gene activation is highly relevant to the lens induction process, reflecting the second state being met within the ectoderm. We have found that δ1-crystallin gene is regulated ...
A method for fast database search for all k-nucleotide repeats
A method for fast database search for all k-nucleotide repeats

... A signi cant portion of DNA consists of repeating patterns of various sizes, from very small (one, two and three nucleotides) to very large (over 300 nucleotides). Although the functions of these repeating regions are not well understood, they appear important for understanding the expression, regul ...
chromosome disorders.
chromosome disorders.

... chromosomes that fuse near the centromere region with loss of the short arms • The resulting balanced karyotype has only 45 chromosomes, including the translocation chromosome, which in effect is made up of the long arms of two chromosomes. • Although Robertsonian translocations involving all combin ...
Separation of DNA Restriction Fragments by Ion
Separation of DNA Restriction Fragments by Ion

... (B) The purified DNA is often contaminated with agarose impurities having enzyme-inhibiting properties (2-5). This prob’ To whom ...
Of mice and (wo)men: genotype–phenotype
Of mice and (wo)men: genotype–phenotype

... transcriptional regulation might explain the different phenotypes observed among different Brca1 mouse models. Complete or partial loss of DNA repair function may account for the observed early embryonic lethality in the Brca1null models. The developmental defects observed in these embryos closely r ...
recommended breeding policy for the maine
recommended breeding policy for the maine

... Dominant White (W) Also known as the White Masking Gene. This gene when heterozygous, (W/w) will present as a fully white cat. However, the gene masks both colour and pattern, and a white cat can produce kittens that show the underlying colour and pattern, as well as fully white kittens. Orange (O) ...
Chromosomal translocations deregulated BCL6
Chromosomal translocations deregulated BCL6

... transcripts could encode a normal full-length BCL6 protein whose translation would be initiated from its normal initiation codon (50 nucleotides 3' to the IgH-BCL6 junction in exon 3). In summary, our analysis of the 5' terminus of BCL6 RNA indicated that in all three NHL cases the der(3) chromosome ...


... The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles (“cards”) on genes, leukaemias, solid tumours, canc ...
C. neoformans
C. neoformans

asian breeding policy - Maine Coon Breed Society
asian breeding policy - Maine Coon Breed Society

... three forms of tabby pattern were inherited as an allelic series; however it now appears as if at least two, and probably three, different loci are responsible for the various tabby patterns (Lorimer, 1995). At one locus are the alleles for mackerel and blotched (classic) tabby patterns with mackere ...
Evolutionary history of the genus Capra
Evolutionary history of the genus Capra

... PCR was performed with 45 cycles (95 °C 30 s, 60 °C 40 s, and 72 °C 40 s). Two PCR products (320 and 400 bp) were obtained for males. The Bos sequences show that the AMELY protein is about 60 bp shorter than the AMELX protein. The 320 bp Y-chromosome-linked band was therefore puriWed using a QIAquic ...
Azza Ahmed Ibrahim Abo senna_GST paper
Azza Ahmed Ibrahim Abo senna_GST paper

... leukemia has revealed a great number of non-random chromosome abnormalities. In many instances, molecular studies of these abnormalities identified specific genes implicated in the process of leukemogenesis (Mrozek et al., 2004) The environmental causes of acute leukemia, which have increased in the ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... etiologies remain unknown. It is defined as the loss of three or more consecutive pregnancies prior to the 20th week of gestation and affects 5% of couples (20,21). Several studies suggest that gene poly-morphisms encoding for different mediators may represent a susceptibility factor for unexplained ...
Bioinformatics Sequencing
Bioinformatics Sequencing

... The dynamic programming approach to sequence alignment always tries to follow the best prior-result so far. Try to align two sequences by inserting some gaps at different locations, so as to maximize the score of this alignment. Score measurement is determined by "match award", "mismatch penalty" an ...
3 -2 -1 -2 -1 1 2 K
3 -2 -1 -2 -1 1 2 K

... • There are two kinds of scores: raw scores (calculated from a substitution matrix) and bit scores (normalized scores) • Bit scores are comparable between different searches because they are normalized to account for the use of different scoring matrices and different database sizes ...
Genomic Analysis of Arabidopsis Thaliana
Genomic Analysis of Arabidopsis Thaliana

... preferred plant model is based upon its small genome size and few repetitive sequences. The framework for Arabadopsis genomics was set by early kinetic analyses of total Arabidopsis DNA in 1984. Most of the genome was found to be composed of singlecopy sequences (50–57%), with repetitive sequences ( ...
RNA interference pathways display high rates of adaptive protein
RNA interference pathways display high rates of adaptive protein

... transposable elements (TEs) in the germ line, and piRNAs are derived from endogenously-encoded piRNA clusters of inactivated TE sequences and from active TEs (Klattenhoff & Theurkauf, 2008; Thomson & Lin, 2009; Czech, et al., 2016). Nevertheless, within this simple framework there is substantial var ...
sheet l .06 slide 2 (lipids)
sheet l .06 slide 2 (lipids)

... -LDL is rich in cholesterol esters which get uptaken by receptor-mediated endocytosis. *formation of Foam cells  Macrophages derived from monocytes can uptake LDL via specific receptors, as a result of this macrophages will contain cholesterol. - LDL receptors are susceptible to down regulation bas ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.

... designated as KiSS-1 (Lee et al, 1996). The gene was given its name because of its location on chromosome-1, the original nomenclature of the KiSS-1 gene and its product (kisspeptin) was discovered at the Pennsylvania State College of Medicine in Hershey, therefore to associate this discovery with t ...
Article Old but Not (So) Degenerated—Slow
Article Old but Not (So) Degenerated—Slow

... (that X-linked expression of both sexes would equalize autosomal expression) may at least in part have to be revised (Xiong et al. 2010; Julien et al. 2012; Lin et al. 2012; Pessia et al. 2012). Birds are organisms with female heterogamety, that is, males have two copies of the Z chromosome and fema ...
5 Genetic Analysis of Kidney Disease in Mice
5 Genetic Analysis of Kidney Disease in Mice

... genes in these small regions were tested using two expression databases to determine if the genes were expressed in the tissues relevant to the phenotype. Those genes meeting this criterion were then examined for coding sequence differences using first a database and then actual sequencing. These ge ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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