alignable - gobics.de: Department of Bioinformatics
... P(f) = probability of finding a fragment “like f” by chance in random sequences with same length as input sequences w(f) = -log P(f) (“weight score” of f) ”like f” means: at least same # matches (DNA, RNA) or sum of similarity values (proteins) ...
... P(f) = probability of finding a fragment “like f” by chance in random sequences with same length as input sequences w(f) = -log P(f) (“weight score” of f) ”like f” means: at least same # matches (DNA, RNA) or sum of similarity values (proteins) ...
Domain-Specific Synonym Expansion and
... If the topic contains “TGF beta”, documents talking about “TGF beta 1” or “TGF beta 2” are probably relevant as well. For every gene descriptor in the database, a search key was added with the last part of the gene symbol removed so that “TGF beta 1” can be found when searching for “TGF beta”. Why “ ...
... If the topic contains “TGF beta”, documents talking about “TGF beta 1” or “TGF beta 2” are probably relevant as well. For every gene descriptor in the database, a search key was added with the last part of the gene symbol removed so that “TGF beta 1” can be found when searching for “TGF beta”. Why “ ...
The physics behind the larger scale organization of DNA in eukaryotes
... [19]. This might point to a 3-ribbon structure. The small discrepancy can be attributed to the approximations involved in the model that start to matter at such small fiber diameters. 2.3. Energetics: elasticity and electrostatics One important property we need to address is the energetics involved ...
... [19]. This might point to a 3-ribbon structure. The small discrepancy can be attributed to the approximations involved in the model that start to matter at such small fiber diameters. 2.3. Energetics: elasticity and electrostatics One important property we need to address is the energetics involved ...
Monitoring BCR-ABL transcript levels by real-time
... method for monitoring the response to treatment in patients with chronic myeloid leukemia (CML) who have been induced into complete cytogenetic remission.1 Recently, various methods based on RQ-PCR have been adopted to monitor residual disease in clinical studies. An attempt to standardize this meth ...
... method for monitoring the response to treatment in patients with chronic myeloid leukemia (CML) who have been induced into complete cytogenetic remission.1 Recently, various methods based on RQ-PCR have been adopted to monitor residual disease in clinical studies. An attempt to standardize this meth ...
Beyond The Classical Cystic Fibrosis
... Since 1989, it has become well known that CF is an ion channel disorder caused by mutations in the gene for the CF transmembrane conductance regulator (CFTR) [16]. The CFTR gene is located on the long (q) arm of chromosome 7 (7q31.2) [17,18]. ...
... Since 1989, it has become well known that CF is an ion channel disorder caused by mutations in the gene for the CF transmembrane conductance regulator (CFTR) [16]. The CFTR gene is located on the long (q) arm of chromosome 7 (7q31.2) [17,18]. ...
Shoot Branching and Leaf Dissection in Tomato Are
... tomato, we found six homologs in Arabidopsis (Müller et al., 2006) and seven in grape (Vitis vinifera). As shown by phylogenetic analysis, this group is clearly separate from other R2R3 repeat MYB genes (Stracke et al., 2001; Wilkins et al., 2009). Alignment of the amino acid sequences of these pro ...
... tomato, we found six homologs in Arabidopsis (Müller et al., 2006) and seven in grape (Vitis vinifera). As shown by phylogenetic analysis, this group is clearly separate from other R2R3 repeat MYB genes (Stracke et al., 2001; Wilkins et al., 2009). Alignment of the amino acid sequences of these pro ...
Both Polymorphic Variable Number of Tandem Repeats
... The INS-VNTR locus consists of a 14 –15 base pair (bp) consensus sequence unit (ACAGGGGTCTGGGG) with slight variations of the repeat subtype units. The number of repeats ranges from 26 to more than 200, but differences in length are not randomly distributed. Intensive linkage analysis on different p ...
... The INS-VNTR locus consists of a 14 –15 base pair (bp) consensus sequence unit (ACAGGGGTCTGGGG) with slight variations of the repeat subtype units. The number of repeats ranges from 26 to more than 200, but differences in length are not randomly distributed. Intensive linkage analysis on different p ...
Early frameshift alleles of zebrafish tbx5a that fail to
... mRNA expression of versican a (vcana) in homozygous tbx5aΔ5 mutants was expanded in tbx5a-mutant hearts (Fig. 1V,W). All these phenotypes are well-documented for both tbx5a morphants in which tbx5a mRNA is downregulated via morpholino injection7,9,10,18 and in embryos homozygous for the classic tbx5 ...
... mRNA expression of versican a (vcana) in homozygous tbx5aΔ5 mutants was expanded in tbx5a-mutant hearts (Fig. 1V,W). All these phenotypes are well-documented for both tbx5a morphants in which tbx5a mRNA is downregulated via morpholino injection7,9,10,18 and in embryos homozygous for the classic tbx5 ...
Inferring Host Gene Subnetworks Involved in Viral
... a variety of host intracellular interactions. The output is an ensemble of subnetworks that provides a consistent explanation for the measured phenotypes, predicts which unassayed host factors modulate the virus, and predicts which host factors are the most direct interfaces with the virus. We infer ...
... a variety of host intracellular interactions. The output is an ensemble of subnetworks that provides a consistent explanation for the measured phenotypes, predicts which unassayed host factors modulate the virus, and predicts which host factors are the most direct interfaces with the virus. We infer ...
COMMISSION ON GENETIC RESOURCES FOR FOOD AND
... question of liability” as one of the most appropriate for further work and decided that it should be taken into consideration when designing the Commission’s Multi-Year Programme of Work. This background study paper gives an overview of current research regarding the full range of possible effects o ...
... question of liability” as one of the most appropriate for further work and decided that it should be taken into consideration when designing the Commission’s Multi-Year Programme of Work. This background study paper gives an overview of current research regarding the full range of possible effects o ...
Puffs and PCR: the in vivo dynamics of early gene
... gland lobe had been analysed cytologically following propioniccarmine-orcein staining (see Ashburner, 1967). The RNA preparation is derived from the method of Richards et al. (1983). Tubes were allowed to thaw on ice and then vortexed vigorously, which was as effective for the extraction of RNA as c ...
... gland lobe had been analysed cytologically following propioniccarmine-orcein staining (see Ashburner, 1967). The RNA preparation is derived from the method of Richards et al. (1983). Tubes were allowed to thaw on ice and then vortexed vigorously, which was as effective for the extraction of RNA as c ...
illustra bacteria genomicPrep Mini Spin Kit
... consistent, reproducible yields of gDNA. In comparative tests with QIAamp DNA Mini Kit, the yield from genomicPrep was 20% more than that from QIAamp (Table 2). Additionally, the coefficient of variation for genomicPrep yields was about half of that for QIAamp (25.5% vs 50%, respectively), which dem ...
... consistent, reproducible yields of gDNA. In comparative tests with QIAamp DNA Mini Kit, the yield from genomicPrep was 20% more than that from QIAamp (Table 2). Additionally, the coefficient of variation for genomicPrep yields was about half of that for QIAamp (25.5% vs 50%, respectively), which dem ...
Applet for calculating heritability for threshold traits
... Most quantitative traits exhibit some degree of heritability. The heritability is evident when individuals, deviating positively or negatively from the average, also become offspring with deviation in the same trait in the same direction as their parents. There is a continuum of some traits, which i ...
... Most quantitative traits exhibit some degree of heritability. The heritability is evident when individuals, deviating positively or negatively from the average, also become offspring with deviation in the same trait in the same direction as their parents. There is a continuum of some traits, which i ...
Gene Section PYY (peptide YY) Atlas of Genetics and Cytogenetics
... Loss of PYY expression has been implicated in the development and progression to colon adenocarcinoma. PYY expression has been associated with elevated differentiation, whilst PYY treatment of colon cancers resulted in selected overexpression of enzymes frequently identified in the normal colonocyti ...
... Loss of PYY expression has been implicated in the development and progression to colon adenocarcinoma. PYY expression has been associated with elevated differentiation, whilst PYY treatment of colon cancers resulted in selected overexpression of enzymes frequently identified in the normal colonocyti ...
Green Fluorescent Protein-Glucocorticoid Receptor Knockin Mice
... expressed within a cell determines the magnitude and nature of the response to GCs. It has been observed that both overexpression of GR and expression of antisense GR mRNA in transgenic mice alters thymocyte survival in vitro and in vivo (9 –11). Furthermore, the relative ratio of GR to other transc ...
... expressed within a cell determines the magnitude and nature of the response to GCs. It has been observed that both overexpression of GR and expression of antisense GR mRNA in transgenic mice alters thymocyte survival in vitro and in vivo (9 –11). Furthermore, the relative ratio of GR to other transc ...
Perspectives in Diabetes Glucokinase Gene Structure
... islet, and insulinoma cDNA libraries indicates that different the mRlVA results in an isoform that is missing 17 amino glucokinase isoforms are generated through alternate splic- acids in a region of the protein situated between the putative ing of the glucokinase gene product. One of these isoforms ...
... islet, and insulinoma cDNA libraries indicates that different the mRlVA results in an isoform that is missing 17 amino glucokinase isoforms are generated through alternate splic- acids in a region of the protein situated between the putative ing of the glucokinase gene product. One of these isoforms ...
Coloured Southdown Sheep - Twisty Tree Ranch Fiber Farm
... attractive colours; as trade in wool became increasingly important in Britain, and white wool commanded a high price, the numbers of flocks of white sheep also increased. By the end of the 18th Century, coloured sheep were comparatively rare, the majority of British sheep breeds being predominantly ...
... attractive colours; as trade in wool became increasingly important in Britain, and white wool commanded a high price, the numbers of flocks of white sheep also increased. By the end of the 18th Century, coloured sheep were comparatively rare, the majority of British sheep breeds being predominantly ...
The Nicotiana tabacum genome encodes two cytoplasmic
... DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thioredoxin h,. Isolation and characterization of a genomic ...
... DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thioredoxin h,. Isolation and characterization of a genomic ...
Development and characterization of DehaloR^2, a novel anaerobic
... were detected over the course of the experiment. In contrast to the microcosms, the sediment-free DehaloR^2 consortium rapidly dechlorinated 320 μM TCE to ethene within 10 days with formation of cis-DCE as the primary DCE intermediate (from day 160 in Fig. 1). DehaloR^2 community structure The struc ...
... were detected over the course of the experiment. In contrast to the microcosms, the sediment-free DehaloR^2 consortium rapidly dechlorinated 320 μM TCE to ethene within 10 days with formation of cis-DCE as the primary DCE intermediate (from day 160 in Fig. 1). DehaloR^2 community structure The struc ...
3+ 3 - NVT Online
... Two gene segregation was noted in Sonora/BT Schomburgk (BTS) population. One slow rusting minor gene is contributed by Sonora and a major gene is contributed by BTS Monogenic segregation for an APR gene from Westonia was noted in a cross made for stripe rust resistance analysis ...
... Two gene segregation was noted in Sonora/BT Schomburgk (BTS) population. One slow rusting minor gene is contributed by Sonora and a major gene is contributed by BTS Monogenic segregation for an APR gene from Westonia was noted in a cross made for stripe rust resistance analysis ...
Host-Plasmid Interactions in Saccharomyces
... reviews). The successful large-scale exploitation of such genetically engineered strains requires the development of new host-plasmid systems that achieve high levels of expression of the recombinant protein during large-scale, and often long-term, fermentation. Of particular importance in this resp ...
... reviews). The successful large-scale exploitation of such genetically engineered strains requires the development of new host-plasmid systems that achieve high levels of expression of the recombinant protein during large-scale, and often long-term, fermentation. Of particular importance in this resp ...
Genetic Control of Seed Shattering in Rice by the
... Nipponbare (Figure 2D). We then used another F2 population crossed with indica cv GLA4 for fine mapping the SHAT2. The SHAT2 locus was finally narrowed down to a 9.7-kb region that encompassed two predicted genes (Figure 2D). Comparison of the 9.7-kb sequences between the wild type and shat2 mutant ...
... Nipponbare (Figure 2D). We then used another F2 population crossed with indica cv GLA4 for fine mapping the SHAT2. The SHAT2 locus was finally narrowed down to a 9.7-kb region that encompassed two predicted genes (Figure 2D). Comparison of the 9.7-kb sequences between the wild type and shat2 mutant ...
Full-Text PDF
... be manipulated in two dimensions on the surface of an array of microelectrodes. Droplets with a wide range of volumes can be manipulated, and processes such as dispensing, splitting, mixing can all be accomplished using appropriate electrode patterns. Digital microfluidics has been used for many mol ...
... be manipulated in two dimensions on the surface of an array of microelectrodes. Droplets with a wide range of volumes can be manipulated, and processes such as dispensing, splitting, mixing can all be accomplished using appropriate electrode patterns. Digital microfluidics has been used for many mol ...
A/a · B/b
... Lactose is composed of one molecule of galactose and one molecule of glucose. A secondary cure would result if all galactose and lactose were removed from the diet. The disorder would be expected not to be dominant, because one good copy of the gene should allow for at least some, if not all, breakd ...
... Lactose is composed of one molecule of galactose and one molecule of glucose. A secondary cure would result if all galactose and lactose were removed from the diet. The disorder would be expected not to be dominant, because one good copy of the gene should allow for at least some, if not all, breakd ...
Gene Signal Estimates from Exon Arrays v1.0
... containing probe sets that interrogate exons of RefSeq (Pruitt and Maglott 2001) genes, mRNAs and ESTs from GenBank (Benson et al. 1999), it also contains probe sets for exons predicted by ab-initio gene finders such as GENSCAN (Burge and Karlin 1997), TWINSCAN (Korf et al. 2001), geneid (Parra et a ...
... containing probe sets that interrogate exons of RefSeq (Pruitt and Maglott 2001) genes, mRNAs and ESTs from GenBank (Benson et al. 1999), it also contains probe sets for exons predicted by ab-initio gene finders such as GENSCAN (Burge and Karlin 1997), TWINSCAN (Korf et al. 2001), geneid (Parra et a ...