IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... The Mn-SOD, SOD2, is one of the major superoxide scavengers in mitochondria, and it catalyzes accumulated superoxide radicals into hydrogen peroxide (H2O2). The Mn-SOD gene contains five exons and spans almost 20 kb located at 6p25. The 47 cytosine-to-thymine (C-47-T) transition at codon 16 in the M ...
... The Mn-SOD, SOD2, is one of the major superoxide scavengers in mitochondria, and it catalyzes accumulated superoxide radicals into hydrogen peroxide (H2O2). The Mn-SOD gene contains five exons and spans almost 20 kb located at 6p25. The 47 cytosine-to-thymine (C-47-T) transition at codon 16 in the M ...
DNA supercoiling factor contributes to dosage
... chromosome (Deuring et al., 2000; Corona et al., 2002; Badenhorst et al., 2002). The chromosome defect in the mutant strains is likely to be the result of an imbalance caused by acetylation by MOF leading to a more open chromatin state, without ISWI working toward a more condensed chromatin state (D ...
... chromosome (Deuring et al., 2000; Corona et al., 2002; Badenhorst et al., 2002). The chromosome defect in the mutant strains is likely to be the result of an imbalance caused by acetylation by MOF leading to a more open chromatin state, without ISWI working toward a more condensed chromatin state (D ...
Horizontal gene transfer from flowering plants to Gnetum
... primers specific for each intron type and sequencing entire introns together with parts of exons b and c, we confirmed (i) the presence of gymnosperm-type introns and exons in all accessions of Gnetum except Gnetum africanum and (ii) the additional presence of angiosperm-type introns and exons in 19 ...
... primers specific for each intron type and sequencing entire introns together with parts of exons b and c, we confirmed (i) the presence of gymnosperm-type introns and exons in all accessions of Gnetum except Gnetum africanum and (ii) the additional presence of angiosperm-type introns and exons in 19 ...
Molecular and Genetic Characterization of a
... changes in color, flavor, and texture. Ripening is a tightly controlled and highly programmed developmental event. Identifying the components of this developmental switch is important not only for manipulating this key plant process but also for understanding the regulation of plant development. The ...
... changes in color, flavor, and texture. Ripening is a tightly controlled and highly programmed developmental event. Identifying the components of this developmental switch is important not only for manipulating this key plant process but also for understanding the regulation of plant development. The ...
Exceptionally high levels of recombination
... local recombination rate is associated with distance to the telomere, GC content, and the number of simple repeats as described for low-recombining genomes. Recombination rate does not decrease with chromosome size. On average 5.7 recombination events per chromosome pair per meiosis are found in the ...
... local recombination rate is associated with distance to the telomere, GC content, and the number of simple repeats as described for low-recombining genomes. Recombination rate does not decrease with chromosome size. On average 5.7 recombination events per chromosome pair per meiosis are found in the ...
paper - Université de Namur
... Mirsky [9] proposed i) that the flexible amino acid backbone of globular proteins or enzymes in their native states does not fold randomly but meanders in space along an invariable and reproducible path specific to each protein; and ii) that this unique, so-called tertiary structure is stabilized ag ...
... Mirsky [9] proposed i) that the flexible amino acid backbone of globular proteins or enzymes in their native states does not fold randomly but meanders in space along an invariable and reproducible path specific to each protein; and ii) that this unique, so-called tertiary structure is stabilized ag ...
Genetics of asthma and atopy Koppelman, Gerard
... coworkers hypothesised that bacterial signals play a functional role in the maturation of the TH-1 type immune response, thereby suppressing the TH-2 type response, which may produce an atopic phenotype. Microbial products, such as lipopolysaccharides (LPS), can provide activation signals for TH-1 m ...
... coworkers hypothesised that bacterial signals play a functional role in the maturation of the TH-1 type immune response, thereby suppressing the TH-2 type response, which may produce an atopic phenotype. Microbial products, such as lipopolysaccharides (LPS), can provide activation signals for TH-1 m ...
Functional Interactions of Genes Mediating Convergent Extension
... controlling the spatiotemporal expression pattern of hedgehog genes are currently not understood. Cyclopia is observed in trilobite (tri) and knypek (kny) mutants with affected convergent extension of the embryonic axis during gastrulation. Here, we demonstrate that tri mutants show a high frequency ...
... controlling the spatiotemporal expression pattern of hedgehog genes are currently not understood. Cyclopia is observed in trilobite (tri) and knypek (kny) mutants with affected convergent extension of the embryonic axis during gastrulation. Here, we demonstrate that tri mutants show a high frequency ...
Inhibition of respiration by Nitric Oxide induces a
... • NO and low O2 induce dormancy regulon expression • Both reversible by removal of NO or provision of O2 • Moleuclar sensor for O2 and NO levels must likely to be heme ...
... • NO and low O2 induce dormancy regulon expression • Both reversible by removal of NO or provision of O2 • Moleuclar sensor for O2 and NO levels must likely to be heme ...
documentation in PDF format
... When you have added more than one filter, you are given the option to match any or all of the rules shown; click the "Update" button once you have made your selection. Certain columns when selected have special features: Location - for this column you may enter genomic coordinates in the format "chro ...
... When you have added more than one filter, you are given the option to match any or all of the rules shown; click the "Update" button once you have made your selection. Certain columns when selected have special features: Location - for this column you may enter genomic coordinates in the format "chro ...
Genetics of Hemophilia
... A promoter site outside the gene, but nearby, serves to regulate transcription (making copies of the gene’s message). Genes consist of exons, with coding information for a protein, and introns, spacers between exons. The message of the gene is transcribed (copied) into messenger RNA (ribonucleic aci ...
... A promoter site outside the gene, but nearby, serves to regulate transcription (making copies of the gene’s message). Genes consist of exons, with coding information for a protein, and introns, spacers between exons. The message of the gene is transcribed (copied) into messenger RNA (ribonucleic aci ...
Review of the p53 Tumor Suppressor Gene and its Role in Gliomas
... genes that not only stimulate growth as proto-oncogenes do, but also act to constrain growth, as is the case with tumor suppressor genes. Cells therefore receive not only growth ...
... genes that not only stimulate growth as proto-oncogenes do, but also act to constrain growth, as is the case with tumor suppressor genes. Cells therefore receive not only growth ...
DOCX format - 129 KB - Office of the Gene Technology Regulator
... a condition of the licence that volunteers are destroyed prior to flowering and a volunteer flowers, then the person responsible for controlling volunteers will have contravened that licence condition. If the licence holder is required to inform the Regulator under the immediately preceding conditio ...
... a condition of the licence that volunteers are destroyed prior to flowering and a volunteer flowers, then the person responsible for controlling volunteers will have contravened that licence condition. If the licence holder is required to inform the Regulator under the immediately preceding conditio ...
Endoderm development in vertebrates: fate mapping
... the mesodermal and ectodermal fate at a relatively early stage compared to other vertebrates. At the 32-cell stage, the vegetal-most blastomeres (Fig. 1D1– 4 Xenopus) have been shown to contribute to the endoderm (Nakamura & Kishiyama 1971; Nakamura et al. 1978; Dale & Slack 1987) and significant en ...
... the mesodermal and ectodermal fate at a relatively early stage compared to other vertebrates. At the 32-cell stage, the vegetal-most blastomeres (Fig. 1D1– 4 Xenopus) have been shown to contribute to the endoderm (Nakamura & Kishiyama 1971; Nakamura et al. 1978; Dale & Slack 1987) and significant en ...
Careful risk assessment needed to evaluate transgenic fish
... donor DNA. Therefore, fish engineered with recombinant DNA derived entirely from fish are considered transgenic. The recombinant DNA sequence, or construct, is usually comprised of several different regions including a start signal or “promoter,” the coding region for the target protein, and a stop si ...
... donor DNA. Therefore, fish engineered with recombinant DNA derived entirely from fish are considered transgenic. The recombinant DNA sequence, or construct, is usually comprised of several different regions including a start signal or “promoter,” the coding region for the target protein, and a stop si ...
Integrated mapping and characterization of the gene underlying the
... homeodomain leucine-zipper class I protein, whose closely related genes in several other plant species have been shown to be involved in regulating leaf morphology. The transcript levels of GhOKRA in shoot apices were positively correlated with the phenotypic expression of the okra leaf trait. Of th ...
... homeodomain leucine-zipper class I protein, whose closely related genes in several other plant species have been shown to be involved in regulating leaf morphology. The transcript levels of GhOKRA in shoot apices were positively correlated with the phenotypic expression of the okra leaf trait. Of th ...
PH4 of Petunia Is an R2R3 MYB Protein That Activates
... species, indicating that this function is well conserved (reviewed in Winkel-Shirley, 2001; Koes et al., 2005). Several studies revealed that these MYB, BHLH, and WD40 proteins could interact physically, indicating that they may operate in one transcription activation pathway and may activate their ...
... species, indicating that this function is well conserved (reviewed in Winkel-Shirley, 2001; Koes et al., 2005). Several studies revealed that these MYB, BHLH, and WD40 proteins could interact physically, indicating that they may operate in one transcription activation pathway and may activate their ...
GFF files
... GFF files On common way for the annotations to be uploaded to annotation servers is through GFF files. GFF (‘Gene-Finding Format’ or ‘General Feature Format’). GFF is a format for describing genes and other features associated with DNA, RNA and protein sequences. It was firstly developed at the Sang ...
... GFF files On common way for the annotations to be uploaded to annotation servers is through GFF files. GFF (‘Gene-Finding Format’ or ‘General Feature Format’). GFF is a format for describing genes and other features associated with DNA, RNA and protein sequences. It was firstly developed at the Sang ...
Non-conflict theories for the evolution of genomic imprinting
... complete silencing of one copy, often varies among tissues and different stages of development, and even among individuals. Moreover, although the direction of imprinting at a particular locus (that is, whether the maternal or paternal copy’s expression is downregulated) is consistent within a speci ...
... complete silencing of one copy, often varies among tissues and different stages of development, and even among individuals. Moreover, although the direction of imprinting at a particular locus (that is, whether the maternal or paternal copy’s expression is downregulated) is consistent within a speci ...
Loss of Hox-A1 (Hox-1.6) function results in the
... Keynes, 1989) and mouse hindbrains (Marshall et al., 1992; Baker and Noden, personal communications) have demonstrated a precise and stereotypic pattern of development of the branchiomotor system (reviewed in Lumsden, 1990). Carbocyanine dye injections made into the cranial ganglia of both control a ...
... Keynes, 1989) and mouse hindbrains (Marshall et al., 1992; Baker and Noden, personal communications) have demonstrated a precise and stereotypic pattern of development of the branchiomotor system (reviewed in Lumsden, 1990). Carbocyanine dye injections made into the cranial ganglia of both control a ...
Pharmacogenetics of warfarin: current status and future
... vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be taken into account. There is increasing interest in whether pharmacogenetics can ac ...
... vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be taken into account. There is increasing interest in whether pharmacogenetics can ac ...
a complex voyage to the X chromosome
... complex localization to the X chromosomes and dosage compensation, suggesting that females carry all of the information necessary for MSL targeting (Kelley et al., 1995). This finding implies that specific sequence elements are associated with the X chromosome that distinguish it from other chromoso ...
... complex localization to the X chromosomes and dosage compensation, suggesting that females carry all of the information necessary for MSL targeting (Kelley et al., 1995). This finding implies that specific sequence elements are associated with the X chromosome that distinguish it from other chromoso ...
ETD Program - OhioLINK Electronic Theses and Dissertations Center
... development, it has very distinct phases of development that can be readily recognized. One stage of development is particularly important to some labs, and that is the formation of large asci, which are meiotic and allow for the studying of the meiotic process. These various features make Neurospor ...
... development, it has very distinct phases of development that can be readily recognized. One stage of development is particularly important to some labs, and that is the formation of large asci, which are meiotic and allow for the studying of the meiotic process. These various features make Neurospor ...
Age-related macular degeneration: a perspective on genetic studies
... studies has shown that the presence of the at-risk haplotype increased the risk of AMD 2.7-fold and accounted for 50% of the attributable risk of AMD in that group.26,27 Another study has shown that individuals homozygous for the risk alleles (representing a tyrosine–histidine change at amino acid 4 ...
... studies has shown that the presence of the at-risk haplotype increased the risk of AMD 2.7-fold and accounted for 50% of the attributable risk of AMD in that group.26,27 Another study has shown that individuals homozygous for the risk alleles (representing a tyrosine–histidine change at amino acid 4 ...