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... Molecular Genetics: DNA, RNA & Protein Synthesis  Structure of a nucleotide  Structure of DNA; base-pairing  DNA replication  Central dogma: DNA  RNA  Protein  DNA v. RNA  Protein synthesis: transcription & translation o mRNA v. rRNA v. tRNA o codon v. anticodon o genetic code chart – be abl ...
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Name: DUE Date: ______ ____ period Chapter 17: From Gene to
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... Read the assigned chapter in the book and complete the directed reading guide. For your own benefit please do not leave this assignment until the night before it its due. This is an individual assignment, as such, it is expected that all work on this will be your own. ...
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... C.  Histone Modification and Gene Expression­ The N­terminal tails of the  histones tend to be accessible on the surface of the nucleosome. It is now  known that Lys residues in these tails are often reversibly acetylated. The  acetylated versions are less positively charged, resulting in less affin ...
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... sequences are maintained, the resultant protein product will be maintained. Bacterial genes are arranged much closer together on prokaryotic chromosomes when compared to genes on human chromosomes. Provide one advantage and one disadvantage for the extra “space” that is contained within human chromo ...
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... which direct E to various sets of promoters specific to the s factors (1). These s s are believed to compete with each other for binding to E (7–10). By changing the relative levels of the {sigma}s, Escherichia coli is thought to coordinate its transcriptional program with growth conditions (11–13). ...
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... o What is the probability that these parents will create this child? What relatives are considered 1, and how many genes do you share in common with these relatives? What about 2 and 3? What does a heritability number mean? What does a concordance study look at? ...
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... What is Biology? The word biology is 1………………………. from the Greek words /bios/ meaning /life/ and /logos/ meaning /study/ and is referred to as the science of life or living matter in all its forms and phenomena, 2………………………. with reference to origin, growth, reproduction, structure, and behaviour. An ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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