BRIEF COMMUNICATION Glutathione S transferase theta 1
... Glutathione S transferase theta 1 (GSTT1) is implicated in the detoxification of different substances, including carcinogens. Recently, an increased incidence of GSTT 1 null genotype was found in myelodysplastic syndromes (MDS) by comparison with a control population. We analyzed GSTT 1 gene by PCR ...
... Glutathione S transferase theta 1 (GSTT1) is implicated in the detoxification of different substances, including carcinogens. Recently, an increased incidence of GSTT 1 null genotype was found in myelodysplastic syndromes (MDS) by comparison with a control population. We analyzed GSTT 1 gene by PCR ...
Supplementary Figures
... target gene after normalization to B2M mRNA levels; error bars denote SEM. *Denotes statistical differences between groups after normalization to B2M mRNA levels; **p<0.01; ***p<0.001; n=3 per group. ...
... target gene after normalization to B2M mRNA levels; error bars denote SEM. *Denotes statistical differences between groups after normalization to B2M mRNA levels; **p<0.01; ***p<0.001; n=3 per group. ...
Gene Section MLL (myeloid/lymphoid or
... Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated gene Variable breakpoints on both genes. Abnormal protein N-term -- AT hook and DNA methyltra ...
... Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated gene Variable breakpoints on both genes. Abnormal protein N-term -- AT hook and DNA methyltra ...
Cerberus regulates left–right asymmetry of the embryonic head and
... turning was scored. When cCer was misexpressed on the right side of stage 6–7 embryos, 10/35 embryos (28%) showed inverted heart looping, whereas none of the 26 embryos that had received mock-transfected cells on the right side showed reversed looping (Table 1). Of the 10 embryos with reversed heart ...
... turning was scored. When cCer was misexpressed on the right side of stage 6–7 embryos, 10/35 embryos (28%) showed inverted heart looping, whereas none of the 26 embryos that had received mock-transfected cells on the right side showed reversed looping (Table 1). Of the 10 embryos with reversed heart ...
Characterization of the chimeric seven
... study contained non-polar methionine at position homologous to 105, similar to GPR with leucine at this position but unlike BPR which has polar Gln (Fig. 3), suggesting that they are green-absorbing rhodopsins. Accordingly, the absorption spectra suggest that all CFR isolates from the Ganges River a ...
... study contained non-polar methionine at position homologous to 105, similar to GPR with leucine at this position but unlike BPR which has polar Gln (Fig. 3), suggesting that they are green-absorbing rhodopsins. Accordingly, the absorption spectra suggest that all CFR isolates from the Ganges River a ...
CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI The
... chromatid. Interestingly, we sometimes detected an unaltered product in addition to the rearranged product with the missegregated haplotype. We hypothesize that these two products may be generated by breakage of a partially replicated sequence near a replication fork with only one side of the break ...
... chromatid. Interestingly, we sometimes detected an unaltered product in addition to the rearranged product with the missegregated haplotype. We hypothesize that these two products may be generated by breakage of a partially replicated sequence near a replication fork with only one side of the break ...
Nucleotide Metabolism - Oregon State University
... OMP Decarboxylase is one of the Most Efficient Enzymes Known and Makes UMP CTP is Synthesized from UTP by CTP Synthetase CTP Synthetase Activated by GTP, Inhibited by CTP and Phosphorylation CTP Synthetase Helps to Balance Purines and Pyrimidines ...
... OMP Decarboxylase is one of the Most Efficient Enzymes Known and Makes UMP CTP is Synthesized from UTP by CTP Synthetase CTP Synthetase Activated by GTP, Inhibited by CTP and Phosphorylation CTP Synthetase Helps to Balance Purines and Pyrimidines ...
The Serratia gene cluster encoding biosynthesis of the red antibiotic
... Serratia 39006, Sma 274, and the undecylprodigiosin biosynthetic cluster (red cluster) from Str. coelicolor A3(2). Lines between the Str. coelicolor red and Serratia pig clusters trace the homologue genes relative positions in the two clusters. Regulatory genes of the red cluster are shown in black, ...
... Serratia 39006, Sma 274, and the undecylprodigiosin biosynthetic cluster (red cluster) from Str. coelicolor A3(2). Lines between the Str. coelicolor red and Serratia pig clusters trace the homologue genes relative positions in the two clusters. Regulatory genes of the red cluster are shown in black, ...
The development and evolutionary origin of barbels in
... LeClair and Topczewski 2010). While most barbels are unbranched, secondary through quaternary branching is found in some species. The point in ontogeny during which barbels develop also varies from embryonic through adult stages. Uses of barbels beyond food detection include luring prey and obtainin ...
... LeClair and Topczewski 2010). While most barbels are unbranched, secondary through quaternary branching is found in some species. The point in ontogeny during which barbels develop also varies from embryonic through adult stages. Uses of barbels beyond food detection include luring prey and obtainin ...
The daily rhythm of mice
... Coupled to the core loop is a second, stabilizing loop (Fig. 1). Mice deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional re ...
... Coupled to the core loop is a second, stabilizing loop (Fig. 1). Mice deficient for the nuclear receptor REV-ERBa showed a shorter period probably due to dampened amplitude of Bmal1 expression [41]. The REV-ERBa protein bound to the promoter region of the Bmal1 gene in the phase of transcriptional re ...
FUNCTIONAL INVESTIGATION OF ARABIDOPSIS
... agent of downy mildew) or salicylic acid (SA) treatments, while seven CalS genes were not affected by these treatments. Among the genes that are induced, CalS1 and CalS12, showed the highest responses. When expressed in npr1, a mutant impaired in the response of pathogen related (PR) genes to SA, th ...
... agent of downy mildew) or salicylic acid (SA) treatments, while seven CalS genes were not affected by these treatments. Among the genes that are induced, CalS1 and CalS12, showed the highest responses. When expressed in npr1, a mutant impaired in the response of pathogen related (PR) genes to SA, th ...
Nucleotide Metabolism
... OMP Decarboxylase is one of the Most Efficient Enzymes Known and Makes UMP CTP is Synthesized from UTP by CTP Synthetase CTP Synthetase Activated by GTP, Inhibited by CTP and Phosphorylation CTP Synthetase Helps to Balance Purines and Pyrimidines ...
... OMP Decarboxylase is one of the Most Efficient Enzymes Known and Makes UMP CTP is Synthesized from UTP by CTP Synthetase CTP Synthetase Activated by GTP, Inhibited by CTP and Phosphorylation CTP Synthetase Helps to Balance Purines and Pyrimidines ...
Entering the second century of maize quantitative genetics
... The difference in genetic architecture between maize and sorghum, rice and Arabidopsis is probably due to the different effective recombination rate each species experiences. Maize is an outcrossing species, so genotypes get shuffled and recombined every generation. Selfing species like rice and Ara ...
... The difference in genetic architecture between maize and sorghum, rice and Arabidopsis is probably due to the different effective recombination rate each species experiences. Maize is an outcrossing species, so genotypes get shuffled and recombined every generation. Selfing species like rice and Ara ...
Syllabus PDF
... a) All recommendations involving clinical medicine must be based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. b) All scientific research referred to, reported or used in CME in support or ...
... a) All recommendations involving clinical medicine must be based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. b) All scientific research referred to, reported or used in CME in support or ...
Threading-based Protein Structure Prediction
... • The total info stored in all chromosomes constitutes a genome • In most multi-cell organisms, every cell contains the same complete set of chromosomes – May have some small different due to mutation ...
... • The total info stored in all chromosomes constitutes a genome • In most multi-cell organisms, every cell contains the same complete set of chromosomes – May have some small different due to mutation ...
Leukaemia Section 11q23 rearrangements in de novo childhood acute myeloid leukemia
... As mentioned throughout, molecular cytogenetic methods have shown that the frequency of MLL gene rearrangements exceeds that of 11q23 translocations detected by conventional cytogenetic method alone. In AML cases in which aberrations affect the 11q23 band, a complementary FISH study should be done t ...
... As mentioned throughout, molecular cytogenetic methods have shown that the frequency of MLL gene rearrangements exceeds that of 11q23 translocations detected by conventional cytogenetic method alone. In AML cases in which aberrations affect the 11q23 band, a complementary FISH study should be done t ...
PDF
... In insects, the precise timing of molting and metamorphosis is strictly guided by a principal steroid hormone, ecdysone. Among the multiple conversion steps for synthesizing ecdysone from dietary cholesterol, the conversion of 7-dehydrocholesterol to 5ketodiol, the so-called ‘Black Box’, is thought ...
... In insects, the precise timing of molting and metamorphosis is strictly guided by a principal steroid hormone, ecdysone. Among the multiple conversion steps for synthesizing ecdysone from dietary cholesterol, the conversion of 7-dehydrocholesterol to 5ketodiol, the so-called ‘Black Box’, is thought ...
Zebrafish Collagen Type I: Molecular and Biochemical
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
... around a central axis11. In the endoplasmic reticulum, type I collagen is synthesized as a pro-collagen molecule characterized by the presence of N- and C-propeptides flanking the triple helical region via two short telopeptides (N- and C- telopeptide). In particular, the C-propeptide contains a var ...
Efficient Family Based Association Tests
... association studies, which traditionally focused on relatively small numbers of SNPs within candidate genes or regions, can now be carried out on a genomic scale. These technological advances, which are revolutionizing human genetics, will greatly impact analytical strategies for family based associ ...
... association studies, which traditionally focused on relatively small numbers of SNPs within candidate genes or regions, can now be carried out on a genomic scale. These technological advances, which are revolutionizing human genetics, will greatly impact analytical strategies for family based associ ...
Centromere Locations and Associated Chromosome
... CEN5 is more complex. The formation of chromosome V of A. thaliana involved a reciprocal translocation (see above and Figure 1), and an understanding of this event is critical for interpreting the origin of CEN5. Previous comparative molecular cytogenetic analyses of A. thaliana and A. lyrata could ...
... CEN5 is more complex. The formation of chromosome V of A. thaliana involved a reciprocal translocation (see above and Figure 1), and an understanding of this event is critical for interpreting the origin of CEN5. Previous comparative molecular cytogenetic analyses of A. thaliana and A. lyrata could ...
Chapter 14 Mendel and the Gene Idea Multiple-Choice
... Chapter 14 Mendel and the Gene Idea Multiple-Choice Questions 1) Pea plants were particularly well suited for use in Mendelʹs breeding experiments for all of the following reasons except that A) peas show easily observed variations in a number of characters, such as pea shape and flower color. B) it ...
... Chapter 14 Mendel and the Gene Idea Multiple-Choice Questions 1) Pea plants were particularly well suited for use in Mendelʹs breeding experiments for all of the following reasons except that A) peas show easily observed variations in a number of characters, such as pea shape and flower color. B) it ...
Functional genomics analysis of the effects of co- decarboxylase/ornithine decarboxylase
... Polyamines are ubiquitous components of all living cells and their depletion usually causes growth arrest or cytostasis, a strategy employed for treatment of West-African trypanosomiasis. In the malaria parasite, Plasmodium falciparum, polyamine biosynthesis is regulated by the uniquely bifunctional ...
... Polyamines are ubiquitous components of all living cells and their depletion usually causes growth arrest or cytostasis, a strategy employed for treatment of West-African trypanosomiasis. In the malaria parasite, Plasmodium falciparum, polyamine biosynthesis is regulated by the uniquely bifunctional ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.