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Isozymes
Isozymes

... The first molecular markers: allozymes Allozymes Enzymes that diifer in amino acid sequence yet catalyze the same reaction -visible as a band on a gel -may exist at several gene loci Isozyme: allelic form of allozyme (same locus) ...
ClickThisLinkForEntries
ClickThisLinkForEntries

... involve multiple products being generated, which are used for reactants in the next step of the pathway. Allosteric inhibitors ensure that there is the right amount of reactants and products to ensure maximum pathway efficiency. A picture from the textbook on the right shows how they work. Interact ...
Princeton H - SchoolNotes
Princeton H - SchoolNotes

... controlled reaction? Be able to interpret graph. H. What are the effects of increasing enzyme concentration on the rate of an enzyme controlled reaction? Be able to interpret graph. I. Why are enzymes needed only in small quantities? J. What is the lock-and-key" model of enzyme action? K. What does ...
Lecture Notes Ch21
Lecture Notes Ch21

... combine molecules using ATP Ch 21 | # 4 of 47 ...
Chapter 5: Microbial Metabolism
Chapter 5: Microbial Metabolism

... anaerobic respiration, it is another inorganic molecule. c. In cyclic photophosphorylation, electrons are returned to chlorophyll. In noncyclic photophosphorylation, chlorophyll receives electrons from ...
Chapter 2
Chapter 2

... Section 2 - Properties of Water • Polarity – a molecule in which the charges are unevenly distributed is a polar molecule. – A water molecule is polar because there is an uneven distribution of electrons between the oxygen and hydrogen atoms. ...
Enzymes and Active Sites
Enzymes and Active Sites

... Nearly all enzymes • are globular proteins with a unique three-dimensional shape that recognizes and binds a small group of reacting molecules, called substrates. • have a tertiary structure that includes a region called the active site where one or more small groups of substrates bind to create a c ...
Enzyme classification take home quiz:
Enzyme classification take home quiz:

... 7. conversion of fat (triacylated glycerol) to a diacylglycerol and a free fatty acid 8. converts L-tyrosine to 3-amino-3-(4-hydroxyphenyl)propanoate 9. catalyzes the reaction of L-serine & pyruvate to 3-hydroxypyruvate and L-alanine 10. catalyzes the NAD dependent reaction of formate to carbon diox ...
3. Metabolism - Professor Monzir Abdel
3. Metabolism - Professor Monzir Abdel

The Chemistry of Life
The Chemistry of Life

... Transport substances into or out of cells or help fight disease ...
Transition
Transition

... Binding Modes of Enzymatic Catalysis • Proper binding of reactants in enzyme active sites provides substrate specificity and catalytic power • Two catalytic modes based on binding properties can each increase reaction rates over 10,000-fold : (1) Proximity effect - collecting and positioning substr ...
What enzymes do do!! Increase the rate of a reaction by lowering the
What enzymes do do!! Increase the rate of a reaction by lowering the

... What enzymes do do!! Increase the rate of a reaction by lowering the activation energy ∆G# Reaction specificity and the activation energy of a reaction Enzymes have evolved special active site pockets which recognise only certain substrates and allow them to bind. This makes enzymes generally more s ...
cytology_enzyme_13
cytology_enzyme_13

... Facts to be explained  Enzymes are proteins  Enzymes are required in minute quantities  Enzymes show striking specificity. They catalyze specific reactions involving specific substrates  Enzymes increase the speed of a chemical reaction - Both forward and backward reaction  The action of enzym ...
Biology-1 Exam Two Sample Questions Substrates bind to an
Biology-1 Exam Two Sample Questions Substrates bind to an

... a. An enzyme's function depends on its three-dimensional shape. b. Enzymes are very specific for certain substrates. c. Enzymes are used up in chemical reactions. d. Enzymes emerge unchanged from the reactions they catalyze. e. An enzyme binds to its substrate at the enzyme's active site. 3. Which o ...
Enzymes - CEA Workshop Teacher Notes.pptx
Enzymes - CEA Workshop Teacher Notes.pptx

... to  assist  enzyme  acJvity   •  A  coenzyme  will  bind  to  a  protein  to  form  an  acJve  enzyme   •  Coenzymes  osen  help  by  carrying  a  group  of  atoms  to  the  acJve   site  which  are  then  transferred  to  the  su ...
1. Most organisms are active in a limited temperature range
1. Most organisms are active in a limited temperature range

... Identify the role of enzymes in metabolism, describe their chemical composition and use a simple model to describe their specificity on substrates Enzyme action • Enzymes - protein molecules acting as biological catalysts, increase the rate of the reactions that occur in living organisms • Intracell ...
Macromolecules and SPF groups
Macromolecules and SPF groups

Metabolic Pathways
Metabolic Pathways

Protein engineering of aldolase: Directed evolution
Protein engineering of aldolase: Directed evolution

... formation of carbon-carbon bonds, a critical process for the synthesis of complex biologically active molecules. We are currently involved in two main areas i) site-directed mutagenesis and X-ray crystallography to study the mechanism of aldolase and ii) directed evolution to create novel aldolases. ...
Chapter 2
Chapter 2

... o I can explain the monomers that make up each of the four macromolecules ...
Microbially Derived Enzymes - Food Allergy Research and
Microbially Derived Enzymes - Food Allergy Research and

L4_bacterial metabolism7e
L4_bacterial metabolism7e

... • Precursor metabolites made from alphaketoglutarate and oxaloacetate ...
5 Kingdoms of Life - Cellular
5 Kingdoms of Life - Cellular

... Enzymes are biological catalysts that speed up reactions but are not consumed by them and therefore can be re-used repeatedly. ...
Chem 464 Biochemistry
Chem 464 Biochemistry

... CO28, carbonic anhydrase changes to H2CO3, pH9 have above effect but in addition CO2 binds to hemoglobin as a carbamate on the NH2 terminal of all for hemoglobin molecules This makes amino terminal negatively charged instead of positively charged. This, in turn, makes an additional salt bridge that ...
FERMENTATION: an anaerobic biological reaction process in which
FERMENTATION: an anaerobic biological reaction process in which

... glycolysis, fatty acid breakdown, the Krebs (citric acid cycle) and electron transport As a result of many control mechanisms, the body oxidizes fats and sugars 5-10 times more rapidly during a period of strenuous exercise than during a period of rest ...
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Enzyme



Enzymes /ˈɛnzaɪmz/ are macromolecular biological catalysts. Enzymes accelerate, or catalyze, chemical reactions. The molecules at the beginning of the process are called substrates and the enzyme converts these into different molecules, called products. Almost all metabolic processes in the cell need enzymes in order to occur at rates fast enough to sustain life. The set of enzymes made in a cell determines which metabolic pathways occur in that cell. The study of enzymes is called enzymology.Enzymes are known to catalyze more than 5,000 biochemical reaction types. Most enzymes are proteins, although a few are catalytic RNA molecules. Enzymes' specificity comes from their unique three-dimensional structures.Like all catalysts, enzymes increase the rate of a reaction by lowering its activation energy. Some enzymes can make their conversion of substrate to product occur many millions of times faster. An extreme example is orotidine 5'-phosphate decarboxylase, which allows a reaction that would otherwise take millions of years to occur in milliseconds. Chemically, enzymes are like any catalyst and are not consumed in chemical reactions, nor do they alter the equilibrium of a reaction. Enzymes differ from most other catalysts by being much more specific. Enzyme activity can be affected by other molecules: inhibitors are molecules that decrease enzyme activity, and activators are molecules that increase activity. Many drugs and poisons are enzyme inhibitors. An enzyme's activity decreases markedly outside its optimal temperature and pH.Some enzymes are used commercially, for example, in the synthesis of antibiotics. Some household products use enzymes to speed up chemical reactions: enzymes in biological washing powders break down protein, starch or fat stains on clothes, and enzymes in meat tenderizer break down proteins into smaller molecules, making the meat easier to chew.
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