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Photo Album
Photo Album

... Figure 3.9 Anaplerotic reactions are required for net synthesis of glutamate, glutamine, and aspartate and for normal synaptic transmission. (A) Net synthesis of TCA cycle-derived amino acids requires the ATP-dependent CO2 fixation reaction catalyzed by pyruvate carboxylase to generate oxaloacetate ...
Chapter 10 - Clayton State University
Chapter 10 - Clayton State University

... • It is also an oxidation because two electrons (and one proton) are transferred to NAD+ to form NADH • Coenzyme A contains the B vitamin • Coenzyme A has a SH group that makes it a good carrier of acetate (and other organic acids) © 2012 Pearson Education, Inc. ...
Fermentation PowerPoint File
Fermentation PowerPoint File

... Lactic acid fermentation can supply enough ATP to last about 90 seconds. However, extra oxygen is required to get rid of the lactic acid produced. Following intense exercise, a person will huff and puff for several minutes in order to pay back the built-up “oxygen debt” and clear the lactic acid fro ...
CELLULAR RESPIRATION
CELLULAR RESPIRATION

... Definition Energy exchange occurring in the cell cytoplasm that does not use oxygen as the final electron acceptor. Aerobic Definition Energy exchange occurring in the mitochondria using oxygen as the final electron acceptor. ...
Lecture Slides for Nitrogen Metabolism
Lecture Slides for Nitrogen Metabolism

amino acid seq lab.pub
amino acid seq lab.pub

... Two proteins are commonly studied in attempting to deduce evolutionary relationships from differences in amino acid sequences. One is cytochrome c, and the other is hemoglobin. Cytochrome c is a protein used in cellular respiration and found in the mitochondria of many organisms. Hemoglobin is the o ...
Amino Acids as Protein Building Blocks [2]
Amino Acids as Protein Building Blocks [2]

... Proteins are naturally-occurring biopolymers comprised of amino acids. ...
BIOCHEMISTRY AND MOLECULAR BIOLOGY Problem Unit Four
BIOCHEMISTRY AND MOLECULAR BIOLOGY Problem Unit Four

... commonly stored as ATP. Anabolism requires catabolism because of its need for energy. Life is characterized by growth, movement, and reproduction. Each of these properties depends on controlled chemical reactions for the biosynthesis of organic compounds (anabolism) and the production of usable ener ...
Intermediary Metabolism-II SECTION A What are ketogenic amino
Intermediary Metabolism-II SECTION A What are ketogenic amino

... Give the structure of epinephrine. What are glucogenic amino acids? What are transminases? Give example. Write a note on creatinine. What is GABA? Explain the action of deaminase. How is pyruvate obtained from amino acids? Explain the significance of serotonin. How is GABA formed? How is α-KG obtain ...
C6_rev - boswellsrcd
C6_rev - boswellsrcd

... (eg could get too hot if exothermic; gas could be produced to quickly and pressure build up) If it is too slow, then product would be made too slowly, and yield low, so profit too low. (economic factors) ...
Review - Columbus Labs
Review - Columbus Labs

... end of eukaryotic mRNA and searches for an AUG codon by moving step-by-step in the 3′ direction. The 5′ cap provides an easily recognizable starting point. 4. Elongation and termination. Eukaryotic elongation factors EF1α and EF1βγ are the counterparts of prokaryotic EF-Tu and EF-Ts. The GTP form of ...
COMPARATIVE MODELING AND MOLECULAR
COMPARATIVE MODELING AND MOLECULAR

... In silico-developed homology protein structure modeling builds a threedimensional model of a given protein sequence based on its similarity to one or more known structures belonging to the same member of a protein family. The purpose of this study is strongly related to a drug discovery strategy aga ...
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File

Photosynthesis_Cell Resp_Jeopardy
Photosynthesis_Cell Resp_Jeopardy

... Metabolic process most closely related with the intracellular membrane. ...
small heat shock protein activity is regulated by
small heat shock protein activity is regulated by

... for 2.5 hr at 70o C and then the solvent was evaporated. The mixture was acidified to pH 1 with aqueous HCl and extracted three times with each 0.4 mL of CHCl3. The extract was dried over sodium sulfate, and concentrated under reduced pressure to afford desired N-Boc-fluoroethyl-L-tyrosine. The depr ...
CONTRIBUTIONS OF ANAEROBIC METABOLISM TO pH
CONTRIBUTIONS OF ANAEROBIC METABOLISM TO pH

... reactions involved in energy production during catabolism of fats, carbohydrates, proteins or amino acids. Oxidation involves the transformation of saturated into unsaturated substances, the formation of carbonyl groups from alcohols, and finally yields acidic carboxyl groups. During formation, howe ...
Evening primrose oil
Evening primrose oil

... formation and the barrier function of superficial skin layers. Some studies revealed that by applying linoleic acid (LA) and γ-linolenic acid (GLA) for some days, transepidermal water loss (TEWL) is reduced. After different treatments with LA or GLA, constant TWEL was observed for several days. Howe ...
Universal Kinase and GTPase Assays
Universal Kinase and GTPase Assays

... Kinases are enzymes that catalyze the transfer of a phosphate group from ATP to some acceptor protein or small molecule, and thereby produce ADP. Most kinases also have ATPase activity, where ATP is hydrolyzed to ADP in the absence of substrate. Kinases, a large family of proteins within the human g ...
CH1710 PrEX#2 Sp2013 answers
CH1710 PrEX#2 Sp2013 answers

... 1. Aqueous copper (II) chloride reacts with aqueous sodium hydroxide to yield solid copper (II) hydroxide and aqueous sodium chloride. ...
ELEM_CouvC_V1n3 copy
ELEM_CouvC_V1n3 copy

... Mineralogy offers insights into this debate, for various minerals may have played many different roles in the transition from geochemistry to biochemistry. Modern life, for the most part, provides few clues about this rocky start, but the complex enzymes that promote cellular metabolism may represen ...
24_Test - Ventura College
24_Test - Ventura College

... Which of the following is not true of metal-ion catalysis? A. It can make a reaction center more susceptible to receiving electrons B. It can make a leaving group a weaker base, and therefore a better leaving group C. It can increase the rate of a hydrolysis reaction by increasing the nucleophilicit ...
Unit 1 - Calderglen High School
Unit 1 - Calderglen High School

... expressed). Tissue stem cells Tissue stem cells replenish differentiated cells that need to be replaced. Unlike embryonic stem cells, they can only produce a limited range of cell types. For example, the stem cells in our bone marrow will only give rise to different types of blood cells e.g. red blo ...
발효화학-8.
발효화학-8.

...  In microbiology, the term ‘fermentation’ can be used to describe either (1) microbial processes that produce useful products or (2) a form of anaerobic microbial growth using internally supplied electron acceptors and generating ATP mainly through substrate-level phosphorylation (SLP).  This chap ...
lecture7
lecture7

... Fatty acid synthesis starts with the carboxylation of acetyl CoA to malonyl CoA. This irreversible reaction is the committed step in fatty acid synthesis. The synthesis of malonyl CoA is catalyzed by acetyl CoA carboxylase, which contains a biotin prosthetic group. The carboxyl group of biotin is co ...
Chapter 6
Chapter 6

... which an insoluble solid (precipitate) drops out of the solution. – Clear solutions of two ionic compounds when mixed form a cloudy solution (cloudiness indicates solid) ...
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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