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Unit 5.1 Review (2)
Unit 5.1 Review (2)

LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different
LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different

... Have spherical (lymphocytes) or kidney-shaped (monocytes) nuclei Lymphocytes ...
Lecture 7: The body`s defenses
Lecture 7: The body`s defenses

... Step 3: Activation ...
Nonspecific Immunity
Nonspecific Immunity

... Delayed hypersensitivity T • Allergic reactions, organ rejection – Suppressor T – Antigen Presenting Cells (APC) • MHC-I • MHC-II ...
factors
factors

... formed in circulation and deposited in vessel walls or other tissues • Not organ specific • Effects caused by activation of complement – chemotaxis of neutrophils • Neutrophils release lysosomal enzymes into tissues (“frustrated phagocytosis”) ...
Immune System - Mr. Mazza's BioResource
Immune System - Mr. Mazza's BioResource

... Helper T cell signaling B cell to differentiate into plasma cell and Memory T-cells cause quicker produce antibodies response if infection with same pathogen occurs again ...
Chapter 40 review notes
Chapter 40 review notes

... 3. pathogen injected into healthy lab mouse 4. healthy mouse becomes sick 5. pathogen identified -Bacteria break down tissues and release toxins -toxins are poisons that produce illness by disrupting bodily functions -Viruses reproduce inside the host cell by using materials of the host cell to make ...
Immune-system-powerpoint
Immune-system-powerpoint

... C = antigen presented on surface of macrophage ...
Immunity - Honors
Immunity - Honors

... What is in the shot they give you? – Dead or inactive (attenuated) pathogens ...
General Defence System
General Defence System

... Phagocytes are white blood cells that have the ability to engulf cellular debris and infectious material like bacteria and viruses. Phagocytes ‘feed’ like Amoeba. Free phagocytes wander throughout tissues ‘searching’ for ‘foreign invaders’. Fixed phagocytes reside in a particular area destroying pat ...
Tissues of the immune system
Tissues of the immune system

... Such as Bone marrow and thymus B- peripheral lymphoid organs or secondary organs Where lymphocytes responses to foreign Ags Such as :spleen ,lymph nodes,cutaneous and mucosal immune system . ...
Typical violations of immunobiological supervision 1. The main
Typical violations of immunobiological supervision 1. The main

... 24. What is the role of B-lymphocyte in the antibody genesis? a) convert antigen into an immunogenic form and differentiate into plasma cells - antibody producers; b) produce an inductor of the immunopoiesis; c) stimulate T-cell system of lymphocytes; + d) under the influence of specific and non-spe ...
Intro to the Immune System
Intro to the Immune System

... 2) diversity – the immune system can produce a hugely diverse set of recognition molecules which allows us to recognize literally billions of molecular shapes 3) memory – once it has responded to an antigen, the system maintains a memory of that Ag 4) self-nonself recognition –the system typically r ...
Week 9: Today`s Program
Week 9: Today`s Program

... Vertebrate lymphocytes take on specialized roles Circulate through blood & lymph, concentrated in spleen & lymph nodes B & T cells bear ~100K antigen receptors (all the same) Antigenbinding sites ...
PowerPoint to accompany
PowerPoint to accompany

... Neutrophils are present in the blood in very large numbers Neutrophils can be rapidly recruited to any site which innitiate inflamatory reactions and/or activates complement Both types of phagocyte possess receptors which enable them to bind and phagocytose microbial organisms These receptors recogn ...
the immune system - World of Teaching
the immune system - World of Teaching

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
Immunity: Short- and Long
Immunity: Short- and Long

... Immunity: Short- and LongTerm Cell Memory Whenever T cells and B cells are activated, some become "memory" cells. ...
The Human Immune System PPT
The Human Immune System PPT

... begin their attack - WBCs normally circulate throughout the blood, but will enter the body’s tissues if invaders are detected ...
Immunology_IX__immunity_against_infections
Immunology_IX__immunity_against_infections

... – Existence of co-infection ...
Lymphatic system Lecture #2
Lymphatic system Lecture #2

File
File

... Homeostasis Maintenance of a constant internal body environment. Innate Front line, first responding side of the immune system Adaptive Second line, specialized arm of the immune system Macrophages example of a first line defense immune cell, very phagocytic in nature. Pathogen infectious agent Hemo ...
Southampton Health Journal
Southampton Health Journal

... junctional communication from adjacent cells when they become sick; it is likely that this response evolved early as an extracellular response to intracellular disease. There have been few studies of gap junctional intercellular communication in phagocytes and lymphocytes. When my second paper was a ...
B Cells respond to antigens by differentiating into plasma cell
B Cells respond to antigens by differentiating into plasma cell

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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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