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Reading Guide for Week 9_10
Reading Guide for Week 9_10

... PRRs. (Also know that in lecture, I kept it simple and referred to them solely as PRRs, but if you talk to an immunologist, they will look at you funny if all you say is “PRRs.” It is best to talk about the specific type of PRR, like TLRs, NLRs, or RLRs.) Where can you find these PRRs and what type ...
The Immune System
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... This is INNATE you were BORN with it. ...
Antibodies - blobs.org
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... Antibodies are groups of proteins which connect to proteins on the surface of particles and cells to label them as invaders and stop them attacking the body. They are produced by special cells in the immune system called plasma cells, which are mature B lymphocytes. Each antibody is made up of light ...
immunology2
immunology2

... 3- acute phase protein.. A* originated from the liver. B* present in blood. C* nature : its group of proteins produce by hepatic cells in low level in healthy body. D* function : in case of infection , macrophage ingest bacteria secrete cytokines ώ activate hepatic cell to secrete large amount of a ...
Chapter 35 – The Immune System – Overview What are pathogens
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... 27. What is the main role of an MHC (major histocompatibility complex)? ...
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... through conjugation. Resistance is quickly spread through many bacteria. ...
Innate Immune Response - Morgan Community College
Innate Immune Response - Morgan Community College

... Toll-like receptors and NOD proteins  Cell membrane proteins that recognize and bind to families of compounds unique to microbes ...
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... – Cell-mediated immune response ...
05 M301 Host Def NS 2011 - Cal State LA
05 M301 Host Def NS 2011 - Cal State LA

... in phagosome (vacuole)  Phagosome pinch off, enter cytoplasm to fuse with lysosome  Digestive enzymes present in lysosome kill the MO  But not all MO killed by lysosomal enzymes ...
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... A) is based on recognition of antigens that are specific to different pathogens. B) is found only in vertebrate animals. C) depends on a newly infected animalʹs previous exposure to the same pathogen. D) is activated immediately upon infection. E) utilizes highly specific antigen receptors on B cell ...
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...  Viral glycoproteins allow the virus to attach and enter the cell. The envelope and cell membrane fuse the viral capsid is released into the cytoplasm. Viral DNA enters the nucleus and the capside is discarded. Host enzymes catalyze the early transcription, and viral mRNA directs the production of ...
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immune system - Solon City Schools

...  Neutrophil- 60% WBC, patrol tissue, large numbers when infected  short lives (die after digesting bacteria) ...
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White Blood Cells (leukocytes)

... Blood contains three types of lymphocytes: A- B cells: B- cells produce antibodies that are associated with pathogens for destruction. In addition to linking function after an attack to cause disease, some B cells become capable of producing antibodies specific for the pathogen to serve as a memory ...
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35-2 Defense Against Infection Worksheet

... 16. Humoral immunity is a response to pathogens in blood and lymph. 17. The first response of humoral immunity to infection is much faster than the second response. 18. Plasma cells are specialized B cells. 19. Cell-mediated immunity involves antibodies. 20. Cell-mediated immunity causes infected bo ...
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IMMUNOLOGICAL TOLERANCE
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... Central tolerance occurs during the maturation of lymphocytes in the central (generative) lymphoid organs, where all developing lymphocytes pass through a stage at which encounter with antigen may lead to cell death or replacement of a self-reactive antigen receptor with a new one ...
Click here to the guide.
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... The ability of the immune system to mount a response to disease is dependent on many complex interactions between the components of the immune system and the invading antigens, or disease-causing agents. Macrophages White blood cells are the main components of the immune system. Some white blood cel ...
Disease and Immunity - Skinners` School Science
Disease and Immunity - Skinners` School Science

... • Over time HIV causes number of T helper cells (important components of the immune system that activate other cells) to fall dramatically • Eventually the immune system starts to fail and AIDS ...
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...  Produces localized redness, swelling, heat, and pain ...
Composition of the Immune System
Composition of the Immune System

... The ability of the immune system to mount a response to disease is dependent on many complex interactions between the components of the immune system and the invading antigens, or disease-causing agents. Macrophages White blood cells are the main components of the immune system. Some white blood cel ...
Chapter 43 Immune System
Chapter 43 Immune System

... cellular and chemical defenses take over • White blood cells that serve as phagocytes that engulf and destroy microbes - also initiate the inflammatory response Four types of phagocytic WBC: 1. Neutrophils – most abundant; life span a few days 2. Macrophages – larger, longer living WBC, but only 5% ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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