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The Immune system
The Immune system

... Some of the activated T and B cells remain as memory cells If another invasion of the same invaders occurs these cells recognize them immediately and start their ...
1 - Lone Star College
1 - Lone Star College

... Composed of blood plasma proteins Activated when pathogens enter the body Amplify the inflammatory response Bind to the surface of pathogens, ensuring that they will be phagocytized Form a membrane attack complex that punches holes in the walls and membranes of bacteria ...
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3 Innate immunity I

... •These cells are phagocytes (eliminate the pathogens) •Activate the innate immune response (by secreted proteins, called cytokines) •Activate the adaptive immune system. Macrophages serve as APCs that display antigens to and activate T lymphocytes ...
LACZIK_Pharmacology - 3.practice
LACZIK_Pharmacology - 3.practice

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THE IMMUNE SYSTEM

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Chapt07 Lecture 13ed Pt 4

... • Antigen must be presented in groove of an HLA (MHC) molecule • Cytotoxic T cells destroy ________ antigenbearing cells • Helper T cells secrete cytokines that control the immune response ...
Host Parasite - De Anza College
Host Parasite - De Anza College

... • Antibody dependent: target cell is coated with antibodies • NK, macrophages, neutrophils and eosinophils will bind to Fc of antibodies • Cells especially eosinophils release chemicals that lyse large pathogens ...
Study Guide for Exam 1
Study Guide for Exam 1

... 17. Be familiar with role played by HEV in secondary lymphoid tissues. 18. Explain what happens when the immune system goes dysfunctional. What happens in AIDS or DiGeorge syndrome? CHAPTER 3. Innate Immunity. 1. Once again be familiar with innate immune defenses and how they protect us from infecti ...
The Immune System
The Immune System

... Natural Passive immunity  When mom’s antibodies cross placenta into fetal circulation Artifical Passive immunity  When someone receives immune serum/gamma globulin ...
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Immunology 1

... response. Lymphocytes are agranular leukocytes. They exist as B or T lymphocytes. B lymphocytes have specific antigen binding receptor which is actually a sort of antibody embedded within the cell membrane. They can recognise whole antigens. T lymphocytes do NOT however, recognize whole antigens, on ...
Immune System
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... stem cells in the yolk sac, liver, and bone  marrow release immature lymphocytes into  the circulation  •  These undifferentiated cells must mature to  be able to react to antigen  •  Maturation occurs differently for B and T  cells ...
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IN THIS ISSUE Improving survival after sepsis Outgrowing

... 2407). The kinase helps protect young children from specific pathogens but is expendable in adults. The TLRs are part of an early infection warning system that recognizes microbial intrusion. Many activated TLRs recruit a kinase called IRAK-4, which switches on immune-boosting transcription pathways ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 6. Antibodies are classified based on the type of light chain they possess. 7. Major histocompatibility complex molecules inherited from both parents are codominantly expressed. 8. Myasthenia gravis is a systemic autoimmune disease. 9. A vaccine contains antibodies that stimulate adaptive immunity t ...
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الرقم : بدون التاريخ : 08/ 11 / 1427

... 19. Which of the is nature of antigens a. Polypeptide b. Lipoprotein c. Glycoprotein d. All of the above 20. T-cell receptors Functions is a. Adhesion function b. Enzymatic function c. a & b d. (b) only 21. Cytokines are as follows a. proteins secreted from the immune cells b. secreted as a result o ...
Adaptive Immune System
Adaptive Immune System

... ◦ Recognize antigens on MHCII ◦ Secrete cytokines to activate other cells ◦ Two major types: Th1 and Th2 ...
HOST DEFENSE COURSE OBJECTIVES At the completion of Host
HOST DEFENSE COURSE OBJECTIVES At the completion of Host

... Recognize how the effector functions of antibodies, T cells, macrophages, neutrophils, and NK cells can eliminate pathogens or lead to pathology. Explain how cells in both innate and acquired immunity can encounter a pathogen first at one site, and then fight an infection at distal sites. Describe t ...
Viral mechanisms for subversion of immune responses
Viral mechanisms for subversion of immune responses

How can your immune system malfunction?
How can your immune system malfunction?

... What happens during an Allergic reaction? • The allergen will bind to receptors on WBC’s stimulating the production of histamines. • Histamines are chemical that call trigger an inflammatory response • May experience wheezing, hives, nausea, or shock • What can we take for ANTIHISTAMINES! allergies ...
The immune system
The immune system

... soluble substances known as antibodies (Ab) ...
Lecture 1: The immune system: an overview
Lecture 1: The immune system: an overview

... soluble substances known as antibodies (Ab) ...
Revise_B2_in_15_mins[1]
Revise_B2_in_15_mins[1]

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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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