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Ch 17
Ch 17

... • the specific response is customized for each pathogen • responsible for acquired immunity • involves antigen-presenting cells and two types of lymphocytes • turns on when needed - inducible • “remembers” the pathogens it has “seen” and goes into action faster the second time • may confer lifelong ...
Name - Medical Mastermind Community
Name - Medical Mastermind Community

... A. Insertion of nucleotides at the D-J junction by terminal deoxynucleotide transferase B. Somatic mutation C. Random selection of V, D, and J gene segments D. Pairing of different alpha and beta chain V regions E. Insertion of nucleotides at the V-J junction by terminal deoxynucleotide transferase ...
o The Lymphatic System and Body Defenses
o The Lymphatic System and Body Defenses

... o Cells and Chemicals: Second Line of Defense Antimicrobial proteins Attack microorganisms Hinder reproduction of microorganisms Most important Complement proteins Interferon o Cells and Chemicals: Second Line of Defense Complement proteins A group of at least 20 plasma proteins Activated when they ...
Immunology powerpoint
Immunology powerpoint

... Autoimmunity diseases and conditions Cancer of the lymph nodes: when lymphocytes undergo a mutation and multiply out of control Rheumatoid arthritis: involves the joints, RF factor is test method Grave’s disease: hyperthyroidism, affects young women, goiter is common side effect as well as exophtha ...
Toxoplasma gondii Infection - Wyoming Scholars Repository
Toxoplasma gondii Infection - Wyoming Scholars Repository

... Symptoms ...
File
File

Taxonomy and Systematics: Seeking Order Amidst Diversity
Taxonomy and Systematics: Seeking Order Amidst Diversity

... Even though many receptors (antibodies or T-cell receptors) encounter a given type of antigen, only the receptors that are compatible will bind to them [Fig. 43.12] This process is known as clonal selection Secreted antibodies constitute a group of proteins called immunoglobulins [Fig. 43.8] Antibod ...
Document
Document

... IL-29. These cytokines have similar gene organisation and bind to receptors of similar structure. However, they all display very different biological activities. Several immune cells produce IL-10 (see Figure 1) but production is also observed in epithelial cells, keratinocytes in the skin and some ...
Natural Killer T Cells
Natural Killer T Cells

... CELLS AND ORGANS OF THE IMMUNE SYSTEM Immune system cells are derived from pluripotent hematopoietic stem cells in the bone marrow. The acquired immune response is subdivided into humoral and cellular immunity, based on participation of two major cell types. In Humoral Immunity, B lymphocytes synthe ...
B cell activation and antibody production
B cell activation and antibody production

... Tumor cells avoid an immune response by binding PD-1 on the surface of T cells. Antibody therapies that block PD-1/PD-1L binding can reactivate the T cell’s response to the tumor. ...
Lymphatic System
Lymphatic System

... Antigen-presenting cells processes and displays antigen of pathogen Displayed antigen must be matched with a circulating helper T cells antibody receptor Helper T cell is activated ...
IMMUNODEFICIENCY
IMMUNODEFICIENCY

“The Immune System”
“The Immune System”

... • Killer T cells destroy our cancerous cells. • Immune system fails to locate and remove cancerous cell, & it multiplies to form a ...
Systemic autoimmune diseases
Systemic autoimmune diseases

Immunity Notes - shscience.net
Immunity Notes - shscience.net

... See body areas become inflamed or swollen ex. Bee sting, pollen ...
The Immune System - Sinoe Medical Association
The Immune System - Sinoe Medical Association

... When a localized area exhibits increased  capillary filtration, hyperemia, and swelling, this  is an indication of  a) Antigens are present b) Antibodies are phagocytizing target cells c) Inflammation is occurring d) An immune response is underway e) Fever is developing ...
Blood Composition
Blood Composition

... immunity = defenses to avoid infection, disease, or other unwanted biological invasion – innate immunity – acquired immunity ...
Cells
Cells

... APCs ingest foreign material, then present antigenic fragments on their cell surface where they are recognized by T-cells APCs: Macrophages & B lymphocytes Interactions between APCs & lymphocytes & lymphocyte-lymphocyte interactions are critical to immune response ...
Blood clotting - Liberty Hill High School
Blood clotting - Liberty Hill High School

... • Function is to protect against infection in various ways: How??? – Phagocytize bacterial/dead cells in the body – Produce proteins (antibodies) that destroy or disable foreign particles – Use chemicals to destroy pathogens or infected cells ...
Chapter 43 - The Immune System
Chapter 43 - The Immune System

...  Histamine: triggers dilation and leakiness of blood vessels ...
Host microbe interactions BIO475 Dr. Dieter M. Schifferli
Host microbe interactions BIO475 Dr. Dieter M. Schifferli

... • Escape the phagosome, to RER, cytoplasm (nutrient rich, multiplication) ...
Defense against infectious disease
Defense against infectious disease

... bind themselves directly to the pathogen, which cuts off the pathogen's ties with other cells in the body bind and cover the pathogen so phagocytic cells can recognize it ...
Cancers of the immune system.
Cancers of the immune system.

... White Blood Cells:five types: -Neutrophils(NE):have sacs (granules) containing enzymes that digest bacteria and other microorganisms; process is called phagocytosis. - Monocytes(MO): made in the bone marrow; macrophages and dendrite cells. ...
Procedure: Read the following paragraphs from the Scientific
Procedure: Read the following paragraphs from the Scientific

... attacking diseases that are caused or exacerbated by faulty signaling in cells--among them cancer, diabetes and disorders of the immune system. Next, read the following passage from the June 17, 2000 Scientific American (no longer available online): Getting a Line on Human Diseases A surprising numb ...
Immune System Powerpoint
Immune System Powerpoint

... Nonspecific responses are the same for every pathogen. In inflammation, blood vessels become leaky. – white blood cells move toward infection and damaged tissue – characterized by swelling, redness, and pain ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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