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AP.Blog Immunity
AP.Blog Immunity

... • Plants, invertebrates and vertebrates have multiple, nonspecific immune responses – Invertebrates lack pathogen-specific defense responses – Plant defenses include molecular recognition with systemic responses, infection triggers chemical responses that destroy infected and adjacent cells, localiz ...
Ch 12 2nd and 3rd Lines of Defense
Ch 12 2nd and 3rd Lines of Defense

... Disorders of Immunity: Autoimmune Diseases • Examples of autoimmune diseases (continued) • Systemic lupus erythematosus (SLE) – attacks connective tissue in general. Affects kidney, heart, lung and skin • Glomerulonephritis – impairment of renal function ...
Chapter 19 Blood Lecture Outline
Chapter 19 Blood Lecture Outline

... (blood “clot” = big mesh of fibrin: cells will later get trapped in it making it appear red) ...
2012 Cellular imaging at 3 T
2012 Cellular imaging at 3 T

... • Tissue injury caused by bacteria, trauma, chemicals, or any other phenomenon –Inflammation. • Walling- off • Within minutes after inflammation occurs macrophages already present in the tissues (microglia, Kupffer cells,..) begins their phagocytic action. • The second line of defence within the fir ...
HyperMED | OXYMED Australia
HyperMED | OXYMED Australia

Autoimmune T cells—not always the bad guys
Autoimmune T cells—not always the bad guys

Immune System - ilovebiology
Immune System - ilovebiology

...  Able to distinguish self vs. non-self invaders  Has a role in immunity ...
integumentary, immune and lymphatic systems
integumentary, immune and lymphatic systems

... becomes swollen and painful due to white blood cell accumulation. ...
Study Questions – Body Defenses and Immune System
Study Questions – Body Defenses and Immune System

Document
Document

... Initiation of adaptive immunity Antigen-presenting cells are functionally-defined cells that are able initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as APC ...
AP Biology: Immune System WebQuest
AP Biology: Immune System WebQuest

... Low pH that inhibits or stops bacterial or fungal growth Chemicals that disrupt viruses Normal bacterial flora that crowd out pathogenic bacteria. This is a nonspecific defense. What is an “antigen”? An antigen is an invader. How was the name “antigen” derived? Carefully draw an antibody and its ant ...
Chapter 14 Lymphatic System and Immunity
Chapter 14 Lymphatic System and Immunity

... providing cell-mediated immunity. The activation of this cell requires the presence of an antigen-presenting cell, such as a B cell or macrophage, that has already encountered the antigen. There are several kinds of T cells. In order for a __________________ T cell to become activated, it must first ...
TUTORIAL 4 Multiple Choices For each of the questions below
TUTORIAL 4 Multiple Choices For each of the questions below

The Lymphatic System
The Lymphatic System

... • B cells become immunocompetent and selftolerant in bone marrow • Some self-reactive B cells are inactivated (anergy) while others are killed • Other B cells undergo receptor editing in which there is a rearrangement of their receptors ...
The Immune System
The Immune System

... • A white blood cell engulfs a microbe, then fuses with a lysosome to destroy the microbe • Macrophages are part of the lymphatic system and are found throughout the body Antimicrobial Proteins • Attack microbes directly or impede their reproduction • Interferon proteins provide defense against viru ...
09_Fact_Path_Vir_2_2012_Dent - IS MU
09_Fact_Path_Vir_2_2012_Dent - IS MU

... - starts to operate relatively late, after immune reaction has developed - after repeated contact it acts more quickly and efficiently Tools Antigen-presenting cells (phagocytes) T cells and activated macrophages (cell-mediated immunity) B cells and producers of antibodies (humoral immunity) ...
Immune System
Immune System

... B-Cells develop in 2 stages 1. pre-B cells develop by few months of age (“inactive B cells”) 2. stage two (activation) in lymph nodes & spleen  Antigen binds to antibody receptor…they clone selves  Activated B = “plasma cells” (make antibodies)  Some remain as “memory B cells” ...
c. Section 1.3 The Immune System
c. Section 1.3 The Immune System

... • B cells make antibodies, which bind to antigens to make them harmless or mark them for destruction by other white blood cells – Must have a perfect fit = lock and key – This can take time – this is why you can be sick for days/weeks. ...
Immunity Mediated by B Cells and Antibodies
Immunity Mediated by B Cells and Antibodies

... IMMUNITY MEDIATED BY B LYMPHOCYTES AND ANTIBODIES * B lymphocytes recognize extracellular pathogens and toxins transported to secondary lymphoid tissues * Recognition stimulates proliferation and differentiation into * Plasma cells and memory B cells ...
Foundations in Microbiology
Foundations in Microbiology

... • APCs modify the antigen so it is more immunogenic and recognizable; then the Ag is moved to the APC surface and bound to MHC receptor. • Antigen presentation involves a direct collaboration among an APC, a T helper cell and an antigen-specific B or T cell. – Interleukin-1 is secreted by APC to act ...
What is immunology - British Society for Immunology
What is immunology - British Society for Immunology

... Initiation of adaptive immunity Antigen-presenting cells are functionally-defined cells that are able too initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as ...
Suggested Answers to Discussion topics
Suggested Answers to Discussion topics

... infections. Macrophages in particular that are located in the lung and liver (two organs that are affected with Daniel’s alpha-1 antitrypsin history) are primarily responsible for their phagocytic ability. The fact that activated macrophages impact on the self-nonself response and adaptive immunity ...
What is immunology - British Society for Immunology
What is immunology - British Society for Immunology

... Initiation of adaptive immunity Antigen-presenting cells are functionally-defined cells that are able too initiate adaptive immune responses by presenting antigen to T cells. Major APCs are dendritic cells (DCs), which are found throughout the body – however macrophages and B cells may also serve as ...
The immune system - Los Angeles Mission College
The immune system - Los Angeles Mission College

... injured tissue. This attraction is known as positive chemotaxis. ...
document
document

... antibodies or monoclonal antibodies are produced by recombinant technology. ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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