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Tumor necrosis factor antagonist mechanisms of action: A
Tumor necrosis factor antagonist mechanisms of action: A

... Division of Clinical Immunology and Rheumatology, FOCIS Center of Excellence, Academic Medical Center/University of Amsterdam, F4-218, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands b ...
The Placebo Effect
The Placebo Effect

... 115,000 papers can be found. Most of the papers are clinical trials in which an active treatment is compared with a placebo, some are reviews about placebo effects in pharmacotherapy and psychotherapy, and others are papers dealing with both social and philosophical implications of the placebo pheno ...
IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque
IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque

Immunological and Genetic Aspects of Narcolepsy
Immunological and Genetic Aspects of Narcolepsy

Role of extracellular ATP in immunity and intestinal defence
Role of extracellular ATP in immunity and intestinal defence

... The project described within this thesis was based on the results of a previous randomized clinical trial, reported in 2000 by Agteresch et al. [2], in which effects of ATP infusions in patients with advanced nonsmall-cell lung cancer (NSCLC, tumor stage IIIB and IV) had been investigated. In this r ...
SERIES ‘‘HOT TOPICS IN PAEDIATRIC ASTHMA’’ Number 2 in this Series
SERIES ‘‘HOT TOPICS IN PAEDIATRIC ASTHMA’’ Number 2 in this Series

... previously. Mild exacerbations were not defined because such events can be indistinguishable from loss of asthma control [4]. From a paediatric perspective, these definitions are more difficult to use, taking into account the dependence on parental reporting, as well as the variability among childho ...
The most important aspect of these observations is the fact that an
The most important aspect of these observations is the fact that an

Antigen-Specific Antibody Glycosylation Is Regulated via
Antigen-Specific Antibody Glycosylation Is Regulated via

... dominant subclass in the blood [7]. However, as all vaccinated and infected individuals ultimately produce IgG1 antibodies, it is unclear why some IgG1 responses provide protective immunity while others provide limited immunity at the same titers. While emerging data suggest that the co-selection of ...
Neural substrates for conditioned taste aversion in the rat.
Neural substrates for conditioned taste aversion in the rat.

... coincides with the injection of LiC1 (US), or even when the US precedes the CS by 5 to 10 rain. In other words, when the US precedes the CS more than 10 min. no reliable CTAs can be formed. Comparison of such mterstimulus interval effects on CTA acqmsition together with the aforementioned latency of ...
Update on allergy immunotherapy - Journal of Allergy and Clinical
Update on allergy immunotherapy - Journal of Allergy and Clinical

Humoral and cellular immune responses to Helicobacter
Humoral and cellular immune responses to Helicobacter

... Helicobacter pylori (Hp) colonizes the human gastric and duodenal mucosa and the infection may cause peptic ulcers and gastric adenocarcinoma. Half of the world’s population is infected with Hp with the highest prevalence in developing countries. Hp infection is normally acquired during childhood, b ...
Alice M. Nyakeriga RELATION OF NUTRITIONAL STATUS, IMMUNITY, HEMOGLOBINOPATHY AND
Alice M. Nyakeriga RELATION OF NUTRITIONAL STATUS, IMMUNITY, HEMOGLOBINOPATHY AND

... Immunity and infection: All components of the immune system are important in controlling infection. However, different types of immune responses more effectively control particular infections. The eventual outcome may depend on the biology of the parasite and the characteristic of the specific type ...
Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome
Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome

... with BOS). BAL was cultured for pathogens and ELISA for AMPs was performed. The presence of airway pathogens was associated with significantly increased levels of neutrophil-derived and epithelial-derived AMPs. When patients without pathogens in BAL fluid were analysed, eight recipients with BOS had ...
Anaphylaxis_01 (Pathophysiology)
Anaphylaxis_01 (Pathophysiology)

... proposed to account for reactions to drugs that were solubilized in diluent Cremophor EL, such as older preparations of propofol and paclitaxel. It has been proposed that under physiologic conditions, Cremophor formed large micelles with serum lipids and cholesterol, stimulating complement activatio ...
Wandering womb: a real story of endometriosis
Wandering womb: a real story of endometriosis

... This book is for those who fight back, or who long to. I have lived with this monthly pain since I first began menstruating at the age of twelve. It was a full nine years later that the official diagnosis confirmed my own unofficial one: I had endometriosis. This was not unexpected, as my mother, my ...
The Endocrine System ( PART I) Hormone Overview The Endocrine
The Endocrine System ( PART I) Hormone Overview The Endocrine

... The Endocrine System ( PART I) Hormone Overview Overview  Describe the major endocrine organs, list their main locations and functions.  Indicate important differences between hormonal and neural controls of body functioning.  Why are endocrine glands composed of epithelial tissue?  Define hormo ...
Role and prognostic importance of regulatory T cells in lung cancer
Role and prognostic importance of regulatory T cells in lung cancer

Stimulus Configuration, Classical Conditioning, and
Stimulus Configuration, Classical Conditioning, and

... cells is positively correlated with the topography of the CR. Because one important hippocampal output is mediated through CAS axons that reach the lateral septum, it is not surprising that Berger and Thompson (1978b) and Salvatierra and Berry (1989) reported that neural activity in the lateral sept ...
Effects of insulin under normal and low glucose on retinal
Effects of insulin under normal and low glucose on retinal

... Results. Insulin failed to affect retinal signals at normal glucose levels. However, insulin enhanced the low glucose-induced decrease in rod-driven b-wave amplitude (P < 0.05 at 2 mM; P < 0.01 at 1 mM) without affecting the corresponding changes in the optic nerve response. The standing potential i ...
Responses of Primate Caudal Parabrachial Nucleus and Ko¨lliker
Responses of Primate Caudal Parabrachial Nucleus and Ko¨lliker

... aspect of the superior vestibular nucleus, the caudoventral aspect (pars ␣) of the lateral vestibular nucleus, and the caudal half of the medial vestibular nucleus and the inferior vestibular nucleus (Balaban 1996; Balaban and Beryozkin 1994; Porter and Balaban 1997; Ruggiero et al. 1996; Yates et a ...
Differential Expression of the Melatonin Receptor in Human
Differential Expression of the Melatonin Receptor in Human

... bination of MLT and IL-2, compared with IL-2 alone, increases the number of T lymphocytes, NK cells, and eosinophils (18, 24 –26). In addition to its immunoregulatory properties, MLT displays oncostatic properties (27–30). For instance, MLT induces the antitumoral functions of human monocytes in vit ...
Chapter 3. Characterising αCXCR3-9C5
Chapter 3. Characterising αCXCR3-9C5

... patient Stacey Walters without whom I could not have succeeded in my Masters and to Nathan Zammit who laid the foundation for this work. It has been a pleasure to get to know and work with you all. Thank you to my amazing partner Luke, who has remained my rock over the past two years, through all of ...
Power of Neem The Power of Neem The Power of
Power of Neem The Power of Neem The Power of

Histones Activate the NLRP3 Inflammasome in Kupffer Cells during
Histones Activate the NLRP3 Inflammasome in Kupffer Cells during

... by their restoration, and it leads to ischemic organ damage and inflammation-mediated reperfusion injury (1). Liver I/R injury inevitably occurs after liver resection, organ transplantation, massive trauma, or hemorrhagic shock. There are two distinct stages of liver I/R. First, the ischemic insult ...
The amygdala - University of Puget Sound
The amygdala - University of Puget Sound

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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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