A hemolysis–hemagglutination assay for characterizing
... IgG (monomeric) and IgA (dimeric) forms have been reported [17]. A variety of functions have been proposed for NAbs, including directly controlling novel bacterial and viral disease challenges, enhancing antigen presentation and initiating specific responses of B and T cells, regulating self reactiv ...
... IgG (monomeric) and IgA (dimeric) forms have been reported [17]. A variety of functions have been proposed for NAbs, including directly controlling novel bacterial and viral disease challenges, enhancing antigen presentation and initiating specific responses of B and T cells, regulating self reactiv ...
Elevated interleukin (IL)-35-related sCD14 but not IL
... [20]. Therefore, we further evaluated IL-35 and IL-23 expression on GCF and blood serum of CP patients matched healthy volunteers (HV) by ELISA. Consistent with our previous report, IL-35 levels were higher in CP patients than that of HV control both on GCF (Figure 1A) and blood serum (Figure 1B) be ...
... [20]. Therefore, we further evaluated IL-35 and IL-23 expression on GCF and blood serum of CP patients matched healthy volunteers (HV) by ELISA. Consistent with our previous report, IL-35 levels were higher in CP patients than that of HV control both on GCF (Figure 1A) and blood serum (Figure 1B) be ...
Expanding roles for CD4+ T cells in immunity to viruses
... viruses19. In fact, several studies have found that, far from promoting antiviral responses, TH2 cell-associated mediators (and IL‑4 in particular) have a strong negative impact on immune protection and drive immunopathology during infection with many viruses, including influenza virus20,21, respir ...
... viruses19. In fact, several studies have found that, far from promoting antiviral responses, TH2 cell-associated mediators (and IL‑4 in particular) have a strong negative impact on immune protection and drive immunopathology during infection with many viruses, including influenza virus20,21, respir ...
HIV-1 IMMUNE RESPONSES INDUCED BY NATURAL INFECTION
... pandemic. The onset of AIDS is caused by a slow degeneration of the immune system as a consequence of HIV‐1 infection. Thus the infection may have a silent period for many years before onset of serious symptoms. During this asymptomatic period the host is highly infectious and the virus c ...
... pandemic. The onset of AIDS is caused by a slow degeneration of the immune system as a consequence of HIV‐1 infection. Thus the infection may have a silent period for many years before onset of serious symptoms. During this asymptomatic period the host is highly infectious and the virus c ...
Functions of the skin microbiota in health and disease
... transient depending on their ability to populate the skin-resident microbes survive on the skin for long periods of time, whereas transient microbes may be detected during one sampling event and absent the next. However, as we have seen earlier, the most influential factor in regards to the microbes ...
... transient depending on their ability to populate the skin-resident microbes survive on the skin for long periods of time, whereas transient microbes may be detected during one sampling event and absent the next. However, as we have seen earlier, the most influential factor in regards to the microbes ...
Coinfections following Influenza Immune Dysfunction and Bacterial
... A concept that has recently gained traction in the field is that innate bacterial clearance in the lung is somehow impaired by influenza infection. Alveolar macrophages are the major cell population in the normal airway, and these cells form the first line of defense against respiratory infection. A ...
... A concept that has recently gained traction in the field is that innate bacterial clearance in the lung is somehow impaired by influenza infection. Alveolar macrophages are the major cell population in the normal airway, and these cells form the first line of defense against respiratory infection. A ...
Lessening Malaria Parasite Burden with Yogurt
... system, as well as from the skin on the breast of the mother, and are transferred orally to a newborn (6). The types of microbes transferred to the child are not constant within one mother for the child’s entire time breastfeeding; they are altered based on the age of the infant. For example, newbo ...
... system, as well as from the skin on the breast of the mother, and are transferred orally to a newborn (6). The types of microbes transferred to the child are not constant within one mother for the child’s entire time breastfeeding; they are altered based on the age of the infant. For example, newbo ...
crosstalk between epithelial cells and macrophages - DORAS
... TNFR2 – Maja Kristek In order to cope with the overwhelming amount of commensal bacteria, dietary and environmental antigens, homeostasis in the intestine relies upon the fine tuned crosstalk between the immune cells and their environment. One of the key regulators of homeostasis in the intestine ar ...
... TNFR2 – Maja Kristek In order to cope with the overwhelming amount of commensal bacteria, dietary and environmental antigens, homeostasis in the intestine relies upon the fine tuned crosstalk between the immune cells and their environment. One of the key regulators of homeostasis in the intestine ar ...
Enrichment of IFN-γ producing cells in different murine adipose
... Here we report that lean mice infected with the intracellular parasite Neospora caninum show a fast but sustained increase in the frequency of IFN-γ-producing cells noticeable in distinct adipose tissue depots. Moreover, IFN-γ-mediated immune memory could be evoked in vitro in parasite antigen-stimu ...
... Here we report that lean mice infected with the intracellular parasite Neospora caninum show a fast but sustained increase in the frequency of IFN-γ-producing cells noticeable in distinct adipose tissue depots. Moreover, IFN-γ-mediated immune memory could be evoked in vitro in parasite antigen-stimu ...
Arterioscler Thromb Vasc Biol. - Arteriosclerosis, Thrombosis, and
... Methods and Results—Plaques were obtained from 114 symptomatic subjects referred to carotid endarterectomy and characterized immunohistochemically and histologically. Plasma levels of IgG and IgM against aldehyde-modified apolipoprotein B-100 amino acid sequences 661 to 680, 3136 to 3155 (peptide 21 ...
... Methods and Results—Plaques were obtained from 114 symptomatic subjects referred to carotid endarterectomy and characterized immunohistochemically and histologically. Plasma levels of IgG and IgM against aldehyde-modified apolipoprotein B-100 amino acid sequences 661 to 680, 3136 to 3155 (peptide 21 ...
A COMPARATIVE STUDY OF LEUKOCYTE COUNTS AND
... including the immune system. I obtained mean values of basal white blood cells (WBC) from 100 species of primates to quantify disease risk, based on the assumption that higher baseline WBC counts will be found in species that experience greater risk of acquiring infectious disease. These data were u ...
... including the immune system. I obtained mean values of basal white blood cells (WBC) from 100 species of primates to quantify disease risk, based on the assumption that higher baseline WBC counts will be found in species that experience greater risk of acquiring infectious disease. These data were u ...
Cancer immunotherapy - Italian Sarcoma Group
... New techniques utilizing exome sequencing have been used to identify multiple mutated antigens recognized by TIL. Because melanomas are the only histologic type of cancer that readily gives rise to TIL with demonstrable antitumor activity, a series of clinical trials are using cytokine genes and ant ...
... New techniques utilizing exome sequencing have been used to identify multiple mutated antigens recognized by TIL. Because melanomas are the only histologic type of cancer that readily gives rise to TIL with demonstrable antitumor activity, a series of clinical trials are using cytokine genes and ant ...
Licentiate thesis from the Department of Immunology,
... of infected hepatocytes in combination with MHC class I and then presented to T cells. This presentation results in killing of infected cells by cytotoxic T lymphocytes (CTLs) or through IFN-γ produced by NK and CD4+ T cells which triggers a cascade of immune reactions that ultimately leads to the d ...
... of infected hepatocytes in combination with MHC class I and then presented to T cells. This presentation results in killing of infected cells by cytotoxic T lymphocytes (CTLs) or through IFN-γ produced by NK and CD4+ T cells which triggers a cascade of immune reactions that ultimately leads to the d ...
2. Organization of the Exam and Assessment Criteria
... Near-infrared spectroscopy (NIRS). Transcranial magnetic stimulation. Physical basics of psychophysiological research methods. Temporal and spatial resolution, types of data. PART 4. PSYCHOPHYSIOLOGY OF FUNCTIONAL STATUS General overview on functional status, its regulation and self-regulation. Conn ...
... Near-infrared spectroscopy (NIRS). Transcranial magnetic stimulation. Physical basics of psychophysiological research methods. Temporal and spatial resolution, types of data. PART 4. PSYCHOPHYSIOLOGY OF FUNCTIONAL STATUS General overview on functional status, its regulation and self-regulation. Conn ...
The ontogeny of the common carp (Cyprinus carpio L.) immune system
... stimulants have been reported to induce increased survival, growth, cytokine expression and acute phase protein expression in vitro, proliferation of B cells and the secretion of immunoglobulins (Ig), increased lysozyme levels, and activation of the complement system and macrophages9. Oral administr ...
... stimulants have been reported to induce increased survival, growth, cytokine expression and acute phase protein expression in vitro, proliferation of B cells and the secretion of immunoglobulins (Ig), increased lysozyme levels, and activation of the complement system and macrophages9. Oral administr ...
2. Organization of the Exam and Assessment Criteria
... Near-infrared spectroscopy (NIRS). Transcranial magnetic stimulation. Physical basics of psychophysiological research methods. Temporal and spatial resolution, types of data. PART 4. PSYCHOPHYSIOLOGY OF FUNCTIONAL STATUS General overview on functional status, its regulation and self-regulation. Conn ...
... Near-infrared spectroscopy (NIRS). Transcranial magnetic stimulation. Physical basics of psychophysiological research methods. Temporal and spatial resolution, types of data. PART 4. PSYCHOPHYSIOLOGY OF FUNCTIONAL STATUS General overview on functional status, its regulation and self-regulation. Conn ...
An Introduction to the ANS and Higher
... • Controls during resting conditions • “Rest and digest” ...
... • Controls during resting conditions • “Rest and digest” ...
Allergic disease: the diagnosis of peanut allergy and the role of heat
... the chronic state of allergic diseases such as atopic dermatitis and allergic asthma, leading to tissue remodelling(71;72). It is not yet known if tissue remodelling is also seen in food allergy(73). In addition, TSLP, IL-25 and IL-33, more innate-type cytokines, also seem to contribute to the ...
... the chronic state of allergic diseases such as atopic dermatitis and allergic asthma, leading to tissue remodelling(71;72). It is not yet known if tissue remodelling is also seen in food allergy(73). In addition, TSLP, IL-25 and IL-33, more innate-type cytokines, also seem to contribute to the ...
Theories and Applications of Pavlovian Conditioning
... response is grafted onto the CS, it is not snipped from the UCS” indicates a recognition of CR and UCR differences. The research of Shepard Siegel and his colleagues represents the most impressive accumulation of evidence suggesting that the conditioned and unconditioned responses are different (Sie ...
... response is grafted onto the CS, it is not snipped from the UCS” indicates a recognition of CR and UCR differences. The research of Shepard Siegel and his colleagues represents the most impressive accumulation of evidence suggesting that the conditioned and unconditioned responses are different (Sie ...
RESEARCH THEMES 2015 FOR MSc STUDENTS
... Thanks to the work of researchers round the world, knowledge and skills are developing rapidly in the medical sciences. At the center of each new development is a doctor who has successfully formulated the right questions about patient-related problems and written them up as a research protocol — fo ...
... Thanks to the work of researchers round the world, knowledge and skills are developing rapidly in the medical sciences. At the center of each new development is a doctor who has successfully formulated the right questions about patient-related problems and written them up as a research protocol — fo ...
dendritic cell-based tumor vaccination for high
... LIST OF ABBREVIATIONS APC, allophycocyanine ATRT, atypical teratoid-rhabdoid tumor BBB, blood-brain barrier BTIC, brain tumor-infiltrating cell c.i., confidence interval CNS, central nervous system CTC, Common Toxicity Criteria CTL, cytotoxic T lymphocyte CTLA-4, cytotoxic T lymphocyte-associated a ...
... LIST OF ABBREVIATIONS APC, allophycocyanine ATRT, atypical teratoid-rhabdoid tumor BBB, blood-brain barrier BTIC, brain tumor-infiltrating cell c.i., confidence interval CNS, central nervous system CTC, Common Toxicity Criteria CTL, cytotoxic T lymphocyte CTLA-4, cytotoxic T lymphocyte-associated a ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.