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Defense against disease, immune response
Defense against disease, immune response

... Host - organism or cell on or in which a specific ...
immune response
immune response

... perspiration contain lysozyme which damage or kill bacteria. ...
Disease as a Failure of Homeostasis
Disease as a Failure of Homeostasis

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BSC 361
BSC 361

... Coughing, sneezing and peristalsis Muscles work to move irritants out Chemical defenses: Lysozyme Enzyme in tears and mucus that degrades bacterial cell walls Very important for protection of eyes Stomach acid Low pH conditions prevent most bacteria from persisting in stomach Most GI pathogens have ...
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Inflammatory Immune Response

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no resistance to imminate by pathogens
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Innate Immunity I
Innate Immunity I

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PATH_417_Case_2_Summary_SunnyChen

... • once activated, CD8+ will leave the lymph node and home towards the site of infection and conduct its cytotoxic activity towards infected cells via release the cytotoxins perforin, granzymes, and granulysin • Through the action of perforin, granzymes enter the cytoplasm of the target cell and thei ...
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word - marric.us

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The First and Second Lines of Defense Against Disease
The First and Second Lines of Defense Against Disease

... -Mucous membranes have lysozymes which breaks down bacteria -some cells contain cilia which helps to filter out pathogens or other particles 2nd LINE OF DEFENSE: NON-SPECIFIC RESPONSE: -these are generalized, and random responses to pathogen infection -they consist of various plasma proteins and WBC ...
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PowerPoint 簡報

23. Frenkel lecture: FMD vaccine development - past and future
23. Frenkel lecture: FMD vaccine development - past and future

Endocrinology 5b – Adrenal steroids, anti-inflammatory and
Endocrinology 5b – Adrenal steroids, anti-inflammatory and

... and cytokines in response to complement and antigen o Tissue macrophages – release cytokines, chemoattractants and other mediators, engulf debris, dead cells and micro-organisms o Endothelial cells – release vasodilators and other mediators and contribute to angiogenesis o Fibroblasts – produce matr ...
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Adaptive Immunity

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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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