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IMMUNE SYSTEM
IMMUNE SYSTEM

...  phylogenetically and ontogenetically the oldest defense mechanism  protective response - immune cells, blood vessels, and molecular mediators  eliminate the initial cause of cell injury, clear out necrotic cells and damaged tissues, initiate tissue repair ...
Lecture #24 - Suraj @ LUMS
Lecture #24 - Suraj @ LUMS

Lesson 2 * The Body*s Defenses
Lesson 2 * The Body*s Defenses

...  HIV is the only kind of virus known to attack the human immune system directly and destroy T cells.  Like all viruses, HIV can only produce inside cells. HIV can spread from one person to another only if body fluids from an infected person come in contact with those of an uninfected person.  You ...
Immune System Benchmark Study Guide
Immune System Benchmark Study Guide

... enzyme – breaks down bacterial cell walls and membranes ...
Intro to Immune System Chpt. 1
Intro to Immune System Chpt. 1

... • in periphery they express a unique surface antibody • Plasma cells differentiated B cell, short lifespan, antibody factory • Memory B cell (CD45RO), long life span ...
When a person breaks a bone, suffers infection organ damage or
When a person breaks a bone, suffers infection organ damage or

... Lowering the blood brain barrierto-entry for autologous immune cells When a person breaks a bone, suffers infection organ damage or other injury, the body mounts an immune response, cleaning up the dead and damaged cells, killing bacteria and cells infected with viruses, and stimulating re-growth an ...
Immune System Disorders (Hypersensitivities ≈ Allergies)
Immune System Disorders (Hypersensitivities ≈ Allergies)

... • Cell malfunction due to antibody binding (Grave’s Disease; thyroid gland). • Immune complex forms (rheumatoid arthritis; joints). • Cell-mediated destruction of specific cell types (insulin-dependent diabetes mellitus; insulin-secreting cells of pancreas). • Some individuals are genetically predis ...
How our body fights to keep us healthy
How our body fights to keep us healthy

... Whooping cough ...
What are cytokines and chemokines?
What are cytokines and chemokines?

... Other important facts about Cytokines, Chemokines & Growth Factors • There are functional similarities within ligand ...
Fever and Vomit
Fever and Vomit

... A fever occurs in response to infection, allergies or trauma. Fever inducing agents (Pyrogens) are released by body immune system (white blood cells) or infectious bacteria. A “fever” is the resetting of the thermostat and therefore a higher body temperature. Sometimes localized (cut). The chills ar ...
Cell Mediated Immunity
Cell Mediated Immunity

PowerPoint 프레젠테이션
PowerPoint 프레젠테이션

... Cytokine such as TNF-, and environmental hazards such as inonizing radiation, toxic substances trigger the nuclear translocation of NK-kB via activation of inhibitor-of- NF-kB (IkB) kinase complex (IKK). IKK phosphorylates IkB bound to NF-kB which consists of a dimer of Rel family proteins such as ...
Document
Document

... Autoimmune diseases are multifactorial – genetic & environment Contributing factors • Genetics. Presentation of self-antigens by MHC molecules: Linkage to certain MHC alleles in many autoimmune diseases •Initiating Event: Environmental: Chemical exposure Infection: Viral and bacterial infection mol ...
Lecture 22
Lecture 22

Document
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... a. Some B cells can become activated from binding with antigens that fit in their antigen receptors. Most B cells need helper T cells to activate. b. When activated helper T cells encounter a B cell-antigen complex, they release cytokine proteins that stimulate the B cell to proliferate. 1. Cytokine ...
Module 0:  Foundations in Medicine  Don Smyth & Cindy Ellison
Module 0: Foundations in Medicine Don Smyth & Cindy Ellison

Cells of Immune system
Cells of Immune system

Cells and tissues of the immune system
Cells and tissues of the immune system

... Complement system – non-specific recognition ...
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chapter15

... T cells that secrete cytokines (which are proteins) that mediate local immune responses B cells that secrete high affinity antibodies that noncovalently bind to microbes and their products ...
Immune System
Immune System

... White Blood Cells ~T-Cells~ • T-Cells, often called “natural killer” cells, recognize infected human cells and cancer cells • T-cells will attack these infected cells, quickly kill them, and then continue to search for more cells to kill ...
THE SECRET OF UMBILICAL CORD
THE SECRET OF UMBILICAL CORD

... • A BABY’S UMBILICAL CORD BLOOD IS ...
Host Defenses I: Nonspecific Defenses
Host Defenses I: Nonspecific Defenses

... Describe the role of normal microbiota in innate resistance. Classify phagocytic cells, and describe the roles of granulocytes and monocytes. Define and explain phagocyte and phagocytosis. Explain the different stages of inflammation. Describe the cause and effects of fever. Describe the activativat ...
13hiv aids
13hiv aids

... FL #13 Immune System & HIV Standard 10 EF ...
PowerPoint # 3
PowerPoint # 3

... Parts of the Immune System • Macrophages- A large and versatile immune cell that acts as a microbe, a devouring phagocyte, an antigen presenting cell, and an important source of immune system secretions. • B-cells- Small white blood cells crucial to the immune system defenses. They are also known a ...
Immune System
Immune System

... • Third line of defense • Distinguishes self from non-self • Targets specific antigens • Substance that stimulates immune response • Typically on surface of cells ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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