Microbial Adaptations to the Psychrosphere/Piezosphere
... Synechococcus (Yazawa, 1996; Takeyama et al., 1997). The nucleotide sequence of this DNA was determined and based upon deletion analysis and deduced amino acid homology to other known enzymes involved in fatty acid synthesis, heterocyst glycolipid synthesis and polyketide antibiotic synthesis, six o ...
... Synechococcus (Yazawa, 1996; Takeyama et al., 1997). The nucleotide sequence of this DNA was determined and based upon deletion analysis and deduced amino acid homology to other known enzymes involved in fatty acid synthesis, heterocyst glycolipid synthesis and polyketide antibiotic synthesis, six o ...
Mutational analysis of conserved glutamic acids of
... co-solute. We have addressed the functional importance of two glutamic acid residues at positions 55 and 491. Both residues are highly conserved amongst members of the inorganic phosphate transporter (PiT) family, which might be an indication of functional importance. Moreover, both residues have be ...
... co-solute. We have addressed the functional importance of two glutamic acid residues at positions 55 and 491. Both residues are highly conserved amongst members of the inorganic phosphate transporter (PiT) family, which might be an indication of functional importance. Moreover, both residues have be ...
UNDERSTANDING PKU What is PKU? Phenylketonuria, or PKU
... toxic to the brain even though the person has reached adulthood. Studies show that people off diet: ...
... toxic to the brain even though the person has reached adulthood. Studies show that people off diet: ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... Abstract: A cry gene, obtained from a locally isolated Bt. strain, CAMB # 30382 (isolated from grain dust of Shakargarh, Punjab, Pakistan), highly effective against Tribolium castaneum (Commonly known as red flour beetle), was amplified through Polymerase chain reaction (PCR) by using specific prime ...
... Abstract: A cry gene, obtained from a locally isolated Bt. strain, CAMB # 30382 (isolated from grain dust of Shakargarh, Punjab, Pakistan), highly effective against Tribolium castaneum (Commonly known as red flour beetle), was amplified through Polymerase chain reaction (PCR) by using specific prime ...
PDF
... not acquired by mammalian oocytes until the completion of a final phase of differentiation immediately before ovulation. During this phase, referred to as the maturation period, many intracellular changes occur, including a reprogramming of protein synthesis and the progression of the cell cycle fro ...
... not acquired by mammalian oocytes until the completion of a final phase of differentiation immediately before ovulation. During this phase, referred to as the maturation period, many intracellular changes occur, including a reprogramming of protein synthesis and the progression of the cell cycle fro ...
Alternative Splicing
... In secondary splicing disorders, a regulatory factor which is essential for the process of splicing, is mutated and disturbs splicing activity. Differences in the regulation of splicing activator and/or repressor proteins can have an effect on the alternative splicing pathway. Depending on which spl ...
... In secondary splicing disorders, a regulatory factor which is essential for the process of splicing, is mutated and disturbs splicing activity. Differences in the regulation of splicing activator and/or repressor proteins can have an effect on the alternative splicing pathway. Depending on which spl ...
Physiological state-dependent changes in transcription factor DNA
... lial cells are highly specialized for the synthesis of limited number of proteins during lactation and involution. Regulation of milk protein genes has common features: all of them are expressed only in the mammary gland epithelium during late pregnancy and lactation, their transcription is induced ...
... lial cells are highly specialized for the synthesis of limited number of proteins during lactation and involution. Regulation of milk protein genes has common features: all of them are expressed only in the mammary gland epithelium during late pregnancy and lactation, their transcription is induced ...
Gel electrophoresis lecture
... This project is funded by a grant awarded under the President’s Community Based Job Training Grant as implemented by the U.S. Department of Labor’s Employment and Training Administration (CB-15-162-06-60). NCC is an equal opportunity employer and does not discriminate on the following basis: •again ...
... This project is funded by a grant awarded under the President’s Community Based Job Training Grant as implemented by the U.S. Department of Labor’s Employment and Training Administration (CB-15-162-06-60). NCC is an equal opportunity employer and does not discriminate on the following basis: •again ...
Apple polygalacturonase inhibiting protein1 expressed in transgenic tobacco
... vitro (Wubben et al., 1999), and in order for plants to interact with all these different PGs, plants have evolved different PGIPs with specific PG recognition capabilities (De Lorenzo et al., 2001). Since plants express more than one PGIP, it is difficult to investigate the inhibitory activity of a ...
... vitro (Wubben et al., 1999), and in order for plants to interact with all these different PGs, plants have evolved different PGIPs with specific PG recognition capabilities (De Lorenzo et al., 2001). Since plants express more than one PGIP, it is difficult to investigate the inhibitory activity of a ...
`slow-twitch type` mitochondria, but does not
... an important second messenger controlling many cell functions and processes, including gene expression [11]. Increased biogenesis of mitochondria has been described as consequence of elevated intracellular Ca2+ levels [12]. Although the nuclear targets responsible for Ca2+induced expression of mitoc ...
... an important second messenger controlling many cell functions and processes, including gene expression [11]. Increased biogenesis of mitochondria has been described as consequence of elevated intracellular Ca2+ levels [12]. Although the nuclear targets responsible for Ca2+induced expression of mitoc ...
Leukaemia Section t(5;9)(q14.1;p24) SSBP2/JAK2 Atlas of Genetics and Cytogenetics in Oncology and Haematology
... a). Partial GTG-banded karyotypes showing the t(5;9)(q14.1;p24.1). b). Partial FISH analysis showing the 5'JAK2 hybridization signal on der(5), the 3'JAK2 hybridization signal on der(9) and an intact JAK2 hybridization signal on the normal chromosome 9. ...
... a). Partial GTG-banded karyotypes showing the t(5;9)(q14.1;p24.1). b). Partial FISH analysis showing the 5'JAK2 hybridization signal on der(5), the 3'JAK2 hybridization signal on der(9) and an intact JAK2 hybridization signal on the normal chromosome 9. ...
The twin arginine protein transport pathway exports multiple
... et al., 2005). In general, the sets of candidate Tat substrates predicted by the two programmes show partial but not complete overlap. However to date, where tested, all of those predicted to be Tat substrates by both TATFIND 1.4 and TatP have been shown to have bona fide Tat-targeting signals (Widd ...
... et al., 2005). In general, the sets of candidate Tat substrates predicted by the two programmes show partial but not complete overlap. However to date, where tested, all of those predicted to be Tat substrates by both TATFIND 1.4 and TatP have been shown to have bona fide Tat-targeting signals (Widd ...
Effects of MethionineSulfoxide Reductase (Msr)
... that reduce free and bound oxidized methionine. Two forms of Msr - MsrA and MsrB - are specific for the S and R enantiomers of methionine sulfoxide, respectively. There are three wellcharacterized functions of Msr: It repairs oxidized methionine, acts as a catalytic antioxidant, and regulates certai ...
... that reduce free and bound oxidized methionine. Two forms of Msr - MsrA and MsrB - are specific for the S and R enantiomers of methionine sulfoxide, respectively. There are three wellcharacterized functions of Msr: It repairs oxidized methionine, acts as a catalytic antioxidant, and regulates certai ...
IV RNA Synthesis: Transcription
... Several other types of RNA also occur that are mostly involved in regulation (Chapter 8). These RNA molecules all result from the transcription of DNA. It should be emphasized that RNA operates at two levels, genetic and functional. At the genetic level, mRNA carries genetic information from the gen ...
... Several other types of RNA also occur that are mostly involved in regulation (Chapter 8). These RNA molecules all result from the transcription of DNA. It should be emphasized that RNA operates at two levels, genetic and functional. At the genetic level, mRNA carries genetic information from the gen ...
Introduction to Carbohydrates
... usually found as terminal CHO residues of oligosaccharide side chains of glycoproteins, glycolipids, or, less frequently, of GAGs - The carbons & nitrogens in NANA come from Nacetylmannosamine & PEP Note: before NANA can be added to a growing oligosacch, it must be converted into its active form by ...
... usually found as terminal CHO residues of oligosaccharide side chains of glycoproteins, glycolipids, or, less frequently, of GAGs - The carbons & nitrogens in NANA come from Nacetylmannosamine & PEP Note: before NANA can be added to a growing oligosacch, it must be converted into its active form by ...
BLAST Exercise: Detecting and Interpreting Genetic Homology
... that the sequences have a common function (e.g., that they encode the same protein). There are, of course, limitations to this line of reasoning. For example, two unrelated sequences might appear similar purely by chance. Alternatively, a pair of sequences may be conserved homologs, but they may hav ...
... that the sequences have a common function (e.g., that they encode the same protein). There are, of course, limitations to this line of reasoning. For example, two unrelated sequences might appear similar purely by chance. Alternatively, a pair of sequences may be conserved homologs, but they may hav ...
SGD sample annotations
... - Unannotated genes: Prior to completing our first pass annotation of the entire S. cerevisiae genome in 2003, the lack of any GO annotation in a given aspect indicated that no curator had attempted to find information for that aspect. Now, the un-annotated state should occur only rarely and briefl ...
... - Unannotated genes: Prior to completing our first pass annotation of the entire S. cerevisiae genome in 2003, the lack of any GO annotation in a given aspect indicated that no curator had attempted to find information for that aspect. Now, the un-annotated state should occur only rarely and briefl ...
Full text in pdf - International Microbiology
... that they are members of the large ALDH superfamily, sharing an amino acid identity of 20–30%. Thus, GAPDHNs clearly differ from phosphorylating GAPDHs both in primary structure and molecular mass [10,18,17]. Bacterial and plant enzymes of the GAPDHN family have a much closer affiliation among each ...
... that they are members of the large ALDH superfamily, sharing an amino acid identity of 20–30%. Thus, GAPDHNs clearly differ from phosphorylating GAPDHs both in primary structure and molecular mass [10,18,17]. Bacterial and plant enzymes of the GAPDHN family have a much closer affiliation among each ...
Impact of type 2 diabetes and a - American Journal of Physiology
... zyme that catalyzes the reversible O-GlcNAcylation of specific serine/threonine residues of numerous cytosolic and nuclear proteins (4). Posttranslational O-GlcNAcylation likely interferes with serine/threonine phosphorylation of these same proteins, thereby altering their function. Because protein ...
... zyme that catalyzes the reversible O-GlcNAcylation of specific serine/threonine residues of numerous cytosolic and nuclear proteins (4). Posttranslational O-GlcNAcylation likely interferes with serine/threonine phosphorylation of these same proteins, thereby altering their function. Because protein ...
PowerPoint 簡報
... and specificity of enzymes Binding energy (GB)--- the energy derived from enzyme-substrate interaction 1. Much of the catalytic power of enzymes is ultimately derived from the free energy released in forming multiple weak bonds and interactions between an enzyme and its substrate. This binding ener ...
... and specificity of enzymes Binding energy (GB)--- the energy derived from enzyme-substrate interaction 1. Much of the catalytic power of enzymes is ultimately derived from the free energy released in forming multiple weak bonds and interactions between an enzyme and its substrate. This binding ener ...
Annotation of Drosophila
... Squish: overlapping features appear on separate lines Features are half the height compared to full mode ...
... Squish: overlapping features appear on separate lines Features are half the height compared to full mode ...
Evidence for massive gene exchange between archaeal and
... makes it possible to perform systematic, genome-scale comparisons that aim to delineate the genomic complement of a particular phenotype. Recently, the first genome of a hyperthermophilic bacterium, Aquifex aeolicus, has been sequenced1. Previous studies based on rRNA and aminoacyl-tRNA analysis had ...
... makes it possible to perform systematic, genome-scale comparisons that aim to delineate the genomic complement of a particular phenotype. Recently, the first genome of a hyperthermophilic bacterium, Aquifex aeolicus, has been sequenced1. Previous studies based on rRNA and aminoacyl-tRNA analysis had ...
Diapositive 1 - LBGI Bioinformatique et Génomique Intégratives
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
... Actin Related Proteins (ARPs) are key players in major biological processes important for cell life. In cytoskeleton activities, the ARP2/3 complex is essential for actin dynamics, ARP1 and ARP11 are involved in microtubule based vesicle trafficking, in nuclear functions (transcriptional activation, ...
WormBase-Oct2004 - Gene Ontology Consortium
... to be queried, it is possible to formulate semantic queries. Full text access increases recall of biological data types from 45% to 95%. Extraction of particular biological facts, such as gene-gene interactions, can be accelerated significantly by ontologies, with Textpresso automatically performing ...
... to be queried, it is possible to formulate semantic queries. Full text access increases recall of biological data types from 45% to 95%. Extraction of particular biological facts, such as gene-gene interactions, can be accelerated significantly by ontologies, with Textpresso automatically performing ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.