Plant organelle proteomics
... localisations of organelle membrane proteins ([7,8] Protlocdb: http://bioinf.scri.ac.uk/cgi-bin/ProtLocDB/home). The relatively slow progress may reflect difficulties when expressing GFP-fusions to membrane proteins, where transient over expression, often in a foreign species and cell type, can lead ...
... localisations of organelle membrane proteins ([7,8] Protlocdb: http://bioinf.scri.ac.uk/cgi-bin/ProtLocDB/home). The relatively slow progress may reflect difficulties when expressing GFP-fusions to membrane proteins, where transient over expression, often in a foreign species and cell type, can lead ...
Animal Dicer and plant Dicer-like proteins
... et al., 2012a). This offers significant potential to influence the nuclease activity of the enzyme; yet the functions of both domains appear highly diverse. The helicase domain has been shown to have an inhibitory effect on dsRNA processing by human Dicer (Ma et al., 2008). This domain is also cruci ...
... et al., 2012a). This offers significant potential to influence the nuclease activity of the enzyme; yet the functions of both domains appear highly diverse. The helicase domain has been shown to have an inhibitory effect on dsRNA processing by human Dicer (Ma et al., 2008). This domain is also cruci ...
Application 1
... nanoparticles can serve as useful detection and targeting agents. These AuNPs when encapsulated with carbohydrate ligands can serve as a useful affinity probe for rapid, efficient separation of target proteins followed by on-probe analysis using mass spectroscopy. This technique of protein targeting ...
... nanoparticles can serve as useful detection and targeting agents. These AuNPs when encapsulated with carbohydrate ligands can serve as a useful affinity probe for rapid, efficient separation of target proteins followed by on-probe analysis using mass spectroscopy. This technique of protein targeting ...
Slide ()
... Improper chromosome alignment on the mitotic spindle can activate the spindle checkpoint mediated by the BUB1, BUB3, BUBR1, and MAD2 proteins that localize to kinetochores. An intact spindle checkpoint induces metaphase arrest through inhibition of the APC. Defective spindle-checkpoint function resu ...
... Improper chromosome alignment on the mitotic spindle can activate the spindle checkpoint mediated by the BUB1, BUB3, BUBR1, and MAD2 proteins that localize to kinetochores. An intact spindle checkpoint induces metaphase arrest through inhibition of the APC. Defective spindle-checkpoint function resu ...
The Endocrine System
... Hormones are chemical messengers that are carried by the bloodstream to different cells in the body. Hormones act at a distance from their place of production directly on the target cell, inciting it to increase or decrease the expression of specific genes. Hormones can be either lipid-based, al ...
... Hormones are chemical messengers that are carried by the bloodstream to different cells in the body. Hormones act at a distance from their place of production directly on the target cell, inciting it to increase or decrease the expression of specific genes. Hormones can be either lipid-based, al ...
Leukaemia Section inv(3)(q23q26) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/inv3q23q26ID1276.html DOI: 10.4267/2042/38507 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/inv3q23q26ID1276.html DOI: 10.4267/2042/38507 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Molecular analysis of the operon which encodes the
... from these. Restriction mapping showed three related classes of clone. One clone was digested with a variety of restriction enzymes. Southern blotting showed that none gave a single hybridization-positive band, but digestion with BgAI produced two positive bands, of 4 and 6 kb. These fragments were ...
... from these. Restriction mapping showed three related classes of clone. One clone was digested with a variety of restriction enzymes. Southern blotting showed that none gave a single hybridization-positive band, but digestion with BgAI produced two positive bands, of 4 and 6 kb. These fragments were ...
In this section of the tutorial you will
... phosphorylated in a given residue). By creating a RACE-PRO entry, you are not only requesting a PRO ID for a specific protein form, but also assisting in the curation process. • Define a protein object (based on literature and/or experimental data). The literature or the experiment may describe a se ...
... phosphorylated in a given residue). By creating a RACE-PRO entry, you are not only requesting a PRO ID for a specific protein form, but also assisting in the curation process. • Define a protein object (based on literature and/or experimental data). The literature or the experiment may describe a se ...
Exploring a Protein Structure in the RCSB PDB: T
... Note that there are a few PDB entries listed throughout the feature. For example, PDB entry 1tcr, in the “Antibody Arms” section can be linked from Click on this to open the summary page for the PDB entry 1tcr (http://www.rcsb.org/pdb/explore/explore.do?structureId=1tcr). Read the provided descripti ...
... Note that there are a few PDB entries listed throughout the feature. For example, PDB entry 1tcr, in the “Antibody Arms” section can be linked from Click on this to open the summary page for the PDB entry 1tcr (http://www.rcsb.org/pdb/explore/explore.do?structureId=1tcr). Read the provided descripti ...
![The PRA1 Gene Family in Arabidopsis1[W]](http://s1.studyres.com/store/data/007975965_1-68ff328dd33afa57eaf37e2f089459b4-300x300.png)
The PRA1 Gene Family in Arabidopsis1[W]
... In Arabidopsis, a total of 19 PRA1 (designated AtPRA1) genes were identified and grouped into eight clades (A–H). This classification was based on support values from different phylogenetic tree construction methods (Fig. 1). An overview of the proposed nomenclature and number of homologs per specie ...
... In Arabidopsis, a total of 19 PRA1 (designated AtPRA1) genes were identified and grouped into eight clades (A–H). This classification was based on support values from different phylogenetic tree construction methods (Fig. 1). An overview of the proposed nomenclature and number of homologs per specie ...
PcG, trxG and the maintenance of gene expression
... groups of cells with a specified fate will give rise to their relative body structures. Cell fates are specified by particular combinations of homeotic gene products. During early embryogenesis, maternal and segmentation genes regulate homeotic genes by binding to specific regulatory sequences locat ...
... groups of cells with a specified fate will give rise to their relative body structures. Cell fates are specified by particular combinations of homeotic gene products. During early embryogenesis, maternal and segmentation genes regulate homeotic genes by binding to specific regulatory sequences locat ...
Name - Mrs. Sommers` Class Site
... Identify the functions of the salivary glands, teeth and tongue. Write the structure name next to its description Mouth ...
... Identify the functions of the salivary glands, teeth and tongue. Write the structure name next to its description Mouth ...
Extracellular matrix
... • Collagens: Triple helical rod and non-collagenous domains. Important structural role. Extensive post-translational modifications • Fibronectin: adhesive glycoprotein in matrix and plasma • Proteoglycans: GAG-chains attached to core protein. • Laminins: major components of basement membranes • Matr ...
... • Collagens: Triple helical rod and non-collagenous domains. Important structural role. Extensive post-translational modifications • Fibronectin: adhesive glycoprotein in matrix and plasma • Proteoglycans: GAG-chains attached to core protein. • Laminins: major components of basement membranes • Matr ...
DNA and Proteins - Furman University
... remember, enzymes are proteins that catalyze reactions in the cell. In other words, enzymes are proteins that make stuff all this complex stuff with the energy in ATP. Enzymes make phospholipids, enzymes make sugars, enzymes make DNA, and enzymes make proteins. So, a fundamental question of how life ...
... remember, enzymes are proteins that catalyze reactions in the cell. In other words, enzymes are proteins that make stuff all this complex stuff with the energy in ATP. Enzymes make phospholipids, enzymes make sugars, enzymes make DNA, and enzymes make proteins. So, a fundamental question of how life ...
Sec14p-like proteins regulate phosphoinositide homoeostasis and
... products that share 24–65% primary sequence identity with Sec14p. These Sec14p-like proteins are termed SFH (Sec Fourteen Homologue) proteins, and overexpression of certain individual SFH gene products rescues sec14-1ts -associated growth and secretory defects. SFH proteins are atypical in that thes ...
... products that share 24–65% primary sequence identity with Sec14p. These Sec14p-like proteins are termed SFH (Sec Fourteen Homologue) proteins, and overexpression of certain individual SFH gene products rescues sec14-1ts -associated growth and secretory defects. SFH proteins are atypical in that thes ...
Outer dense fibre protein 2 (ODF2) is a self
... tail outer dense fibres (Brohmann et al., 1997; Shao et al., 1997; Turner et al., 1997; Schalles et al., 1998). The outer dense fibres (ODF) are prominent sperm tail-specific cytoskeletal structures. They consist of nine fibres that accompany the tubuli doublets of the axoneme on its outer edge. At ...
... tail outer dense fibres (Brohmann et al., 1997; Shao et al., 1997; Turner et al., 1997; Schalles et al., 1998). The outer dense fibres (ODF) are prominent sperm tail-specific cytoskeletal structures. They consist of nine fibres that accompany the tubuli doublets of the axoneme on its outer edge. At ...
membrane structure n function
... Figure 10-17. Various ways in which membrane proteins associate with the lipid bilayer. Most trans-membrane proteins are thought to extend across the bilayer as (1) a single a helix, (2) as multiple a helices, or (3) as a rolled-up beta sheet . Some of these "single-pass" and "multipass" proteins h ...
... Figure 10-17. Various ways in which membrane proteins associate with the lipid bilayer. Most trans-membrane proteins are thought to extend across the bilayer as (1) a single a helix, (2) as multiple a helices, or (3) as a rolled-up beta sheet . Some of these "single-pass" and "multipass" proteins h ...
M1 - Biochemistry Transcription III / mRNA Processing
... spliceosome to be efficiently captured as it passes by….etc. ...
... spliceosome to be efficiently captured as it passes by….etc. ...
Powerpoint for Bioinformatics course at CSULA
... lab work anytime soon Experimental proof is still the “Gold Standard”. ...
... lab work anytime soon Experimental proof is still the “Gold Standard”. ...
Making worms that glow in the dark
... The capability to genetically engineer plants and animals so that they glow in the dark began in 1960 in the frigid waters of Puget Sound in the state of Washington. A team of scientists from Princeton University visited the area to collect jellyfish specimens in an attempt to understand the nature ...
... The capability to genetically engineer plants and animals so that they glow in the dark began in 1960 in the frigid waters of Puget Sound in the state of Washington. A team of scientists from Princeton University visited the area to collect jellyfish specimens in an attempt to understand the nature ...
Evolutionary divergence and functions of the ADAM and ADAMTS
... UPDATE ON GENE COMPLETIONS AND ANNOTATIONS ...
... UPDATE ON GENE COMPLETIONS AND ANNOTATIONS ...
Signal Transduction Pathways • Signal Transduction
... threonine in many targets to alter their activity • PKA phosphorylates two enzymes that lead to the breakdown of glycogen (Ch21) •PKA stimulates the expression of specific genes by phosphorylating a transcriptional activator called cAMP response element binding (CREB) protein gene expression ...
... threonine in many targets to alter their activity • PKA phosphorylates two enzymes that lead to the breakdown of glycogen (Ch21) •PKA stimulates the expression of specific genes by phosphorylating a transcriptional activator called cAMP response element binding (CREB) protein gene expression ...
n-formyl methionine
... Formylmethionine (fMet) is an amino acid found in all living cells. It is a derivative of the amino acid methionine. It is a modified form of methionine in which a formyl group has been added to methionine's amino group. It plays a crucial part in the protein synthesis of bacteria, mitochondria and ...
... Formylmethionine (fMet) is an amino acid found in all living cells. It is a derivative of the amino acid methionine. It is a modified form of methionine in which a formyl group has been added to methionine's amino group. It plays a crucial part in the protein synthesis of bacteria, mitochondria and ...
Alpha-Hemoglobin-Stabilizing Protein: An Erythroid Molecular
... implications for normal erythropoiesis and the pathogenesis of hemolytic disorders. Like many other genes that participate in hemoglobin synthesis, AHSP gene expression is controlled by GATA-1 [6], a transcription factor that is essential for the survival and maturation of lineagecommitted erythroid ...
... implications for normal erythropoiesis and the pathogenesis of hemolytic disorders. Like many other genes that participate in hemoglobin synthesis, AHSP gene expression is controlled by GATA-1 [6], a transcription factor that is essential for the survival and maturation of lineagecommitted erythroid ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.