Alfalfa Mob1-like proteins are involved in cell
... [13]. The Arabidopsis genome was searched for cytoskeleton and cytokinesis-related genes. Several kinases, phosphatases and putative mitotic exit network (MEN)/septation initiation network (SIN) components were found in the nucleus, while actin- and microtubule-binding proteins, regulatory proteins ...
... [13]. The Arabidopsis genome was searched for cytoskeleton and cytokinesis-related genes. Several kinases, phosphatases and putative mitotic exit network (MEN)/septation initiation network (SIN) components were found in the nucleus, while actin- and microtubule-binding proteins, regulatory proteins ...
31. The Control of Gene Expression in Prokaryotes
... shown on the right in which each bacterium releases a small molecule into the environment. The molecule is subsequently taken up by other bacterial cells, which start a signaling cascade that s@mulates ...
... shown on the right in which each bacterium releases a small molecule into the environment. The molecule is subsequently taken up by other bacterial cells, which start a signaling cascade that s@mulates ...
Repression of the Defense Gene PR-10a by the Single
... A variety of defense-specific events are induced in plants in response to pathogen infection, including the production of reactive oxygen species, activation of G-proteins, reinforcement of the cell wall, and induction of signal transduction cascades leading to the transcriptional activation of defe ...
... A variety of defense-specific events are induced in plants in response to pathogen infection, including the production of reactive oxygen species, activation of G-proteins, reinforcement of the cell wall, and induction of signal transduction cascades leading to the transcriptional activation of defe ...
Document
... More complex methods are only justified if they can be shown to perform better than simpler methods Simpler methods are only justified if they can perform better than basic sequence alignment ...
... More complex methods are only justified if they can be shown to perform better than simpler methods Simpler methods are only justified if they can perform better than basic sequence alignment ...
video slide
... Anticipatory Questions • 1. What might happen if an organism had its cells expressing all genes within the genome all the time? • 2. At what levels can control of cellular activities/pathways be controlled? • 3. Based on our discussions up to this point, what do you think the term “negative feedback ...
... Anticipatory Questions • 1. What might happen if an organism had its cells expressing all genes within the genome all the time? • 2. At what levels can control of cellular activities/pathways be controlled? • 3. Based on our discussions up to this point, what do you think the term “negative feedback ...
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
... WW domains are very small modules of 35 to 40 residues that also bind proline-rich motifs, commonly with the consensus PPXY or PPLP (Fig. 2E) (25). The WW domains of the E3 ubiquitin protein ligase Nedd4 bind such proline-rich motifs in an amiloridesensitive epithelial Na1 channel, likely leading to ...
... WW domains are very small modules of 35 to 40 residues that also bind proline-rich motifs, commonly with the consensus PPXY or PPLP (Fig. 2E) (25). The WW domains of the E3 ubiquitin protein ligase Nedd4 bind such proline-rich motifs in an amiloridesensitive epithelial Na1 channel, likely leading to ...
Leukaemia Section t(3;3)(p24;q26) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/t0303p24q26ID1277.html DOI: 10.4267/2042/38509 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/t0303p24q26ID1277.html DOI: 10.4267/2042/38509 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Gene Expression and Regulation
... replication and in transcription. Earlier we discussed how genes interact in transmission genetics, based on Mendelian principles. We will now address how gene expression is regulated, primarily at the level of transcription and translation and some of the ways in which we can use our current knowle ...
... replication and in transcription. Earlier we discussed how genes interact in transmission genetics, based on Mendelian principles. We will now address how gene expression is regulated, primarily at the level of transcription and translation and some of the ways in which we can use our current knowle ...
Senior Scientist, Pre-Formulation Development
... Position Overview: This Sr. Scientist position will be responsible for leading activities of formulation development. This position will be capable of screening formulation, performing biophysical characterization testing, and designing and executing stability studies to support formulation developm ...
... Position Overview: This Sr. Scientist position will be responsible for leading activities of formulation development. This position will be capable of screening formulation, performing biophysical characterization testing, and designing and executing stability studies to support formulation developm ...
The mitochondrial uncoupling proteins | Genome Biology | Full Text
... described, and they can be grouped into six families. Most of the described genes are from mammals, but UCP genes have also been found in fish, birds and plants, and there is also functional evidence to suggest their presence in fungi and protozoa. UCPs are encoded in their mature form by nuclear ge ...
... described, and they can be grouped into six families. Most of the described genes are from mammals, but UCP genes have also been found in fish, birds and plants, and there is also functional evidence to suggest their presence in fungi and protozoa. UCPs are encoded in their mature form by nuclear ge ...
Leukaemia Section t(3;12)(q26;q21) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/t0312q26q21ID1280.html DOI: 10.4267/2042/38481 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
... Online updated version: http://AtlasGeneticsOncology.org/Anomalies/t0312q26q21ID1280.html DOI: 10.4267/2042/38481 This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2008 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
CYTOSKELETON II
... production of hair nails and corns). Acidic keratins(type I), basic/neutral keratins(type II). 20 different types of human epitel cells exist 10 type more specific for hair and nails. Some types of type I and II keratins called (hard keratins)(hair, nail and corn) The types of type I and II ...
... production of hair nails and corns). Acidic keratins(type I), basic/neutral keratins(type II). 20 different types of human epitel cells exist 10 type more specific for hair and nails. Some types of type I and II keratins called (hard keratins)(hair, nail and corn) The types of type I and II ...
Unit 4 Cram Sheet
... HLA-DR, HLA-DQ, and HLA-DP – and again, multiple different types. For a transplant to be successful, as many of these need to match as possible. The more that match, the more likely that the recipients body will not reject the transplanted organ. For this reason, tissue typing is an essential step p ...
... HLA-DR, HLA-DQ, and HLA-DP – and again, multiple different types. For a transplant to be successful, as many of these need to match as possible. The more that match, the more likely that the recipients body will not reject the transplanted organ. For this reason, tissue typing is an essential step p ...
1 AGRO/ANSC/BIO/GENE/HORT 305 Fall, 2016 Extension of
... - A lethal allele may produce ratios that seemingly deviate from Mendelian ratios An example is the “creeper” allele in chicken. Creepers have shortened legs and must creep along. Such birds also have shortened wings. Creeper chickens are heterozygous. Creeper allele is lethal in homozygous conditio ...
... - A lethal allele may produce ratios that seemingly deviate from Mendelian ratios An example is the “creeper” allele in chicken. Creepers have shortened legs and must creep along. Such birds also have shortened wings. Creeper chickens are heterozygous. Creeper allele is lethal in homozygous conditio ...
Exercise 4.4 Designing a genetic screen
... 2D-PAGE is not quantitative over the complete range of protein concentrations, which are known to cover several orders of magnitude. There are at least three sources of error: non-stoichiometric extraction of proteins from various cellular constituents, failure of proteins to absorb into or migrate ...
... 2D-PAGE is not quantitative over the complete range of protein concentrations, which are known to cover several orders of magnitude. There are at least three sources of error: non-stoichiometric extraction of proteins from various cellular constituents, failure of proteins to absorb into or migrate ...
9.
... interactors, and, as shown in Fig. 1, the number of interactors influences the rate of evolution. However, we found that proteins that interact do not have similar numbers of interactors (rI1I2 ⫽ 0.02, P ⫽ 0.26). A second possibility is that interacting proteins evolve at similar rates because they ...
... interactors, and, as shown in Fig. 1, the number of interactors influences the rate of evolution. However, we found that proteins that interact do not have similar numbers of interactors (rI1I2 ⫽ 0.02, P ⫽ 0.26). A second possibility is that interacting proteins evolve at similar rates because they ...
PART II
... Food safety is a shared responsibility of industry, farmers, and regulatory authorities. As there is normally no history of safe use for a novel food or food derived from a GM crop, but may be available for both the conventional food and the introduced protein, science based assessment is necessary. ...
... Food safety is a shared responsibility of industry, farmers, and regulatory authorities. As there is normally no history of safe use for a novel food or food derived from a GM crop, but may be available for both the conventional food and the introduced protein, science based assessment is necessary. ...
the Highest Connected Isoforms
... Considerations for multi-omics data integration Michael Tress CNIO, ...
... Considerations for multi-omics data integration Michael Tress CNIO, ...
The K-Segment of Maize DHN1 Mediates Binding
... contains only one K-segment, also displayed a shift in CD values upon incubation with 1:1 PA:PC SUVs but not with 100% PC SUVs (Fig. 5, B and C). The CD spectrum of both DK proteins changed significantly in the far-UV range (190–210 nm). The CD spectrum of DK2 also exhibited a shift in the 210- to 2 ...
... contains only one K-segment, also displayed a shift in CD values upon incubation with 1:1 PA:PC SUVs but not with 100% PC SUVs (Fig. 5, B and C). The CD spectrum of both DK proteins changed significantly in the far-UV range (190–210 nm). The CD spectrum of DK2 also exhibited a shift in the 210- to 2 ...
X-ray crystallography electron microscopy and electron diffraction
... 1 1, 1 –1 and 0 2 results in a blob at the origin of the unit cell and another blob in its center. d) The reflection 0 2 cuts the b edge twice but never the a edge. The phase is 0. ...
... 1 1, 1 –1 and 0 2 results in a blob at the origin of the unit cell and another blob in its center. d) The reflection 0 2 cuts the b edge twice but never the a edge. The phase is 0. ...
publishable summary
... assays, development and improvement of required tools and recruitment of personnel. During the kick-off meeting at hotel Erica, Berg en Dal, The Netherlands in July 2010, the project was initiated and since then has been running smoothly and according to plan. In Workpackage 1, specific progress has ...
... assays, development and improvement of required tools and recruitment of personnel. During the kick-off meeting at hotel Erica, Berg en Dal, The Netherlands in July 2010, the project was initiated and since then has been running smoothly and according to plan. In Workpackage 1, specific progress has ...
Stage and developmental specific gene expression during
... mice. Therefore, it can be concluded that the DNA sequences located between the 400 bp and 900 bp upstream of ATG can function as enhancer elements. For further characterization of DNA cis-acting elements we sequenced about 1 kb of the 5' flanking region of the proaccrosin gene of different mammals. ...
... mice. Therefore, it can be concluded that the DNA sequences located between the 400 bp and 900 bp upstream of ATG can function as enhancer elements. For further characterization of DNA cis-acting elements we sequenced about 1 kb of the 5' flanking region of the proaccrosin gene of different mammals. ...
Lecture 5
... AGAINST their concentration gradient See Fig. 7.16 for a six panel, blow-by-blow description of the sodium-potassium pump. ...
... AGAINST their concentration gradient See Fig. 7.16 for a six panel, blow-by-blow description of the sodium-potassium pump. ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.