Solution structure of the Drosha double-stranded RNA-binding domain Open Access
... MicroRNA (miRNA) are small regulatory RNAs derived from longer RNA transcripts called primary miRNA (pri-miRNA) ([1], reviewed recently in [2]). Pri-miRNA are cleaved by an RNase III family enzyme called Drosha to produce hairpin precursor miRNA (pre-miRNA) [3]. Pre-miRNA are transported to the cyto ...
... MicroRNA (miRNA) are small regulatory RNAs derived from longer RNA transcripts called primary miRNA (pri-miRNA) ([1], reviewed recently in [2]). Pri-miRNA are cleaved by an RNase III family enzyme called Drosha to produce hairpin precursor miRNA (pre-miRNA) [3]. Pre-miRNA are transported to the cyto ...
Metabolic fate and effects of saturated and unsaturated fatty acids in
... been reported to oxidize oleate at significantly lower rates than hepatocytes and to possess a form ofCPT I which is highly sensitive to inhibition by malonyl CoA (6). Fatty acids are also used as structural components within the cell and are incorporated into phospholipids and neutral lipids at rat ...
... been reported to oxidize oleate at significantly lower rates than hepatocytes and to possess a form ofCPT I which is highly sensitive to inhibition by malonyl CoA (6). Fatty acids are also used as structural components within the cell and are incorporated into phospholipids and neutral lipids at rat ...
Biosynthesis of Peptidoglycan in Wall plus Membrane Preparations
... Measurement of chain lengths by bororH1hydride reduction. Purified SDS-soluble and SDS-insoluble peptidoglycans, labelled with 14C in the muramyl residues, were prepared as above. Each purified peptidoglycan was treated with 0.1M-HCl for 2 h at 60 "C. The acid was then removed by rotary evaporation ...
... Measurement of chain lengths by bororH1hydride reduction. Purified SDS-soluble and SDS-insoluble peptidoglycans, labelled with 14C in the muramyl residues, were prepared as above. Each purified peptidoglycan was treated with 0.1M-HCl for 2 h at 60 "C. The acid was then removed by rotary evaporation ...
Supplemental Materials
... major killer of people in tropical regions like Africa. When the red blood cells are sickled, they are destroyed along with the parasites inside. People in Africa that have sickled red blood cells caused by the mutated hemoglobin are more protected from malaria than those with all normal red blood c ...
... major killer of people in tropical regions like Africa. When the red blood cells are sickled, they are destroyed along with the parasites inside. People in Africa that have sickled red blood cells caused by the mutated hemoglobin are more protected from malaria than those with all normal red blood c ...
Alkene epoxidation catalyzed by cytochrome P450 BM-3 139-3 Edgardo T. Farinas,
... arenes, with rates ranging from 1 min21 for microsomal proteins to 3200 min21 for bacterial enzymes.1 Using styrene for comparison, P450cam from Pseudomonas putida is reported to have an initial rate of NADH consumption of 51 min21, with only 2% coupling to styrene oxide formation (1.1 min21).21 Mut ...
... arenes, with rates ranging from 1 min21 for microsomal proteins to 3200 min21 for bacterial enzymes.1 Using styrene for comparison, P450cam from Pseudomonas putida is reported to have an initial rate of NADH consumption of 51 min21, with only 2% coupling to styrene oxide formation (1.1 min21).21 Mut ...
2 - GENCHEM
... Adrenaline is a hormone and neurotransmitter that regulates the supply of oxygen and glucose to the brain and muscles, and one of important regulator of central nervous system (CNS). Mandelic acid, on the other hand, is a main ingredient of almond and believed to be derived from adrenaline as a meta ...
... Adrenaline is a hormone and neurotransmitter that regulates the supply of oxygen and glucose to the brain and muscles, and one of important regulator of central nervous system (CNS). Mandelic acid, on the other hand, is a main ingredient of almond and believed to be derived from adrenaline as a meta ...
Why should we study B12 and Folate? Deficiencies in both are still
... 8. List 5 reactions that require folate coenzymes a. Methylation of Cobalamin b. Addition of the C8 carbon on purine synthesis c. Addition of the C2 carbon in purine synthesis d. Methylation of uracil to make thymidine e. Serine-glycine hydroxymethyl transferase (it makes methyl THF in reverse or us ...
... 8. List 5 reactions that require folate coenzymes a. Methylation of Cobalamin b. Addition of the C8 carbon on purine synthesis c. Addition of the C2 carbon in purine synthesis d. Methylation of uracil to make thymidine e. Serine-glycine hydroxymethyl transferase (it makes methyl THF in reverse or us ...
Dynamic Modeling of Lactic Acid Fermentation Metabolism with
... A single glycerol stock was inoculated into 100 ml of MRS broth and cultured for 15 h in a shaking incubator (SI-600R; Jeiotech, Korea). The culture condition was 33.5oC at 200 rpm, and the cell growth was monitored with the optical density at 600 nm (OD600) using a UV-Vis spectrophotometer (BioSpec ...
... A single glycerol stock was inoculated into 100 ml of MRS broth and cultured for 15 h in a shaking incubator (SI-600R; Jeiotech, Korea). The culture condition was 33.5oC at 200 rpm, and the cell growth was monitored with the optical density at 600 nm (OD600) using a UV-Vis spectrophotometer (BioSpec ...
KINE 4010 Mock Midterm #1
... KINE 4010 Mock Midterm #1 Disclaimer: This exam does not cover the course material in its entirety and should NOT be used as the only source of studying. The questions were made by KAHSSO Peer Tutors. 1. Which of the following about ATP is false? a) It has three phosphates b) It contains a ribose su ...
... KINE 4010 Mock Midterm #1 Disclaimer: This exam does not cover the course material in its entirety and should NOT be used as the only source of studying. The questions were made by KAHSSO Peer Tutors. 1. Which of the following about ATP is false? a) It has three phosphates b) It contains a ribose su ...
Modelling glycolysis with Cellware
... The most important reactions should be considered a little more in detail. In the first reaction enzyme hexokinase phosphorylates glucose and one ATP is consumed (to ADP). This reaction is notable for three reasons: 1) Hexokinase is one of the regulated enzymes in the pathway, 2) phosphorylation tra ...
... The most important reactions should be considered a little more in detail. In the first reaction enzyme hexokinase phosphorylates glucose and one ATP is consumed (to ADP). This reaction is notable for three reasons: 1) Hexokinase is one of the regulated enzymes in the pathway, 2) phosphorylation tra ...
N - WordPress.com
... • For example, the β-adrenergic blockers propranolol undergo Ndeisopropylation to the corresponding primary amines. ...
... • For example, the β-adrenergic blockers propranolol undergo Ndeisopropylation to the corresponding primary amines. ...
The acrylamide problem: a plant and agronomic
... compounds that give fried, roasted, and baked products their colour and a host of other compounds that impart aroma and flavour. These include heterocyclic compounds such as pyrazines, pyrroles, furans, oxazoles, thiazoles, and thiophenes (Mottram, 2007; Halford et al., 2011) (Fig. 1). This makes th ...
... compounds that give fried, roasted, and baked products their colour and a host of other compounds that impart aroma and flavour. These include heterocyclic compounds such as pyrazines, pyrroles, furans, oxazoles, thiazoles, and thiophenes (Mottram, 2007; Halford et al., 2011) (Fig. 1). This makes th ...
Spotlight on metabolic remodelling in heart failure
... which need to be replenished to maintain normal cycle flux. Several pathways exist for the heart to replenish these losses and to maintain normal substrate concentrations. These mechanisms [e.g. pyruvate carboxylation by malic enzyme or the conversion of branched-chain amino acids (BCAA) to succinyl ...
... which need to be replenished to maintain normal cycle flux. Several pathways exist for the heart to replenish these losses and to maintain normal substrate concentrations. These mechanisms [e.g. pyruvate carboxylation by malic enzyme or the conversion of branched-chain amino acids (BCAA) to succinyl ...
Small, Smaller, Smallest: The Origins and Evolution of Ancient Dual
... Many insects rely on bacterial symbionts with tiny genomes specialized for provisioning nutrients lacking in host diets. Xylem sap and phloem sap are both deficient as insect diets, but differ dramatically in nutrient content, potentially affecting symbiont genome evolution. For sap-feeding insects, ...
... Many insects rely on bacterial symbionts with tiny genomes specialized for provisioning nutrients lacking in host diets. Xylem sap and phloem sap are both deficient as insect diets, but differ dramatically in nutrient content, potentially affecting symbiont genome evolution. For sap-feeding insects, ...
A question of taste
... potentially harmful and toxic substances and are thus crucial for survival. There are many sorts of bitter taste receptors, each of which is sensitive to a different bitter substance. ...
... potentially harmful and toxic substances and are thus crucial for survival. There are many sorts of bitter taste receptors, each of which is sensitive to a different bitter substance. ...
ppt file
... The alpha carbon is a chiral center--natural proteins are made of L amino acids (shown above) as opposed to ...
... The alpha carbon is a chiral center--natural proteins are made of L amino acids (shown above) as opposed to ...
Peptide fragmentation - University of Szeged, Department of
... CHR1-CO-...-+NH=CHRi and {CO=N-CHRn-i-CO-...-NH-CHRn-COOH}H+, respectively. Alternatively, when the fragmentation occurs between the -carbon and the amino group c and z or z+1 ions are generated, with structures H2N-CHR1-CO-...-NHCHRiCO-NH3+, {HC(=CR’n-iR”n-i)-CO-...-NH-CHRn-COOH}H+ and {.CHRn-i-CO ...
... CHR1-CO-...-+NH=CHRi and {CO=N-CHRn-i-CO-...-NH-CHRn-COOH}H+, respectively. Alternatively, when the fragmentation occurs between the -carbon and the amino group c and z or z+1 ions are generated, with structures H2N-CHR1-CO-...-NHCHRiCO-NH3+, {HC(=CR’n-iR”n-i)-CO-...-NH-CHRn-COOH}H+ and {.CHRn-i-CO ...
On the trail of protein sequences
... settings, among which was their attachment to carriers for raising antibodies for use as probes in our structural studies. In follow-up discussions to the polyoma–SV40 comparison, Gernot Walter wondered how he might be able to distinguish the newly discovered splicing products of the SV40 large and ...
... settings, among which was their attachment to carriers for raising antibodies for use as probes in our structural studies. In follow-up discussions to the polyoma–SV40 comparison, Gernot Walter wondered how he might be able to distinguish the newly discovered splicing products of the SV40 large and ...
Biosynthesis
Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.