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Poster
Poster

... inhibiting either the active site in the catalytic domain or activating the allosteric site in the C-terminal domain, scientists would be able to shut off the biosynthetic pathway for leucine; thus, preventing Mycobacterium tuberculosis from surviving in the body. The leucine biosynthetic pathway be ...
Exact and pattern searching of protein sequences
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... All hit terms plus 20 words on either side ...
On the role of gut microbiota in intestinal physiology and
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... Shottelius)7,8 , which are somewhat easier to maintain given the fact that they reside in an egg and are more independent after hatching. Küster concluded that the GF goats developed similarly to conventionally raised (CONV-R) counterparts, at the longest experimental duration of 35 days under GF co ...
Table of Available Analyses - NHS Greater Glasgow and Clyde
Table of Available Analyses - NHS Greater Glasgow and Clyde

... Power Failure: In the event of power failure the pneumatic tube should not be used because it takes an hour to purge itself after restoration of power. HISS Requesting: Due to the complex range of tests performed, the HISS system offers over 500 biochemical tests. The following tables are a summary ...
BASIC CONCEPTS OF CHEMISTRY
BASIC CONCEPTS OF CHEMISTRY

... For the thermodynamic description of the system, the state functions are used. These are equations that can be uniquely identified by the parameters P, V and T. The values of these functions are independent of the nature of the process, resulting in a system of this state . The functions of the sta ...
Production of lactic acid using a new homofermentative
Production of lactic acid using a new homofermentative

... preferred component of many food and industrial applications that is currently produced via biological fermentation utilizing lactic acid bacteria or fungi such as Rhizopus. Some recombinant yeast strains have also been used to produce lactic acid from various carbon feedstocks (Porro et al., 2008). ...
as a PDF
as a PDF

... fall far short of those observed. Moreover, if any incorporation of activity into carbon dioxide occurred by mechanisms other than recycling, even less recycling could have taken place. It therefore appears impossible that the radioactivity of carboxyls 2 and 3 is due solely to recycling. A similar ...
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PDF - University of California, San Francisco
PDF - University of California, San Francisco

... site. These domains were identified by reaction with antibodies against synthetic peptides corresponding to specific regions in the molecule. Computer modeling of the reductase structure, based on the amino acid sequence as determined by molecular cloning, predicts that the NHz-terminal domain conta ...
Abstract Background The present study aimed to compare the
Abstract Background The present study aimed to compare the

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The ecology and taxonomy of anaerobic halophilic eubacteria
The ecology and taxonomy of anaerobic halophilic eubacteria

... It is becoming increasingly clear that even such extreme environments as the anaerobic sediments of hypersaline water bodies are inhabited by a variety of microorganisms. A number of fermentative obligate anaerobes have now been isolated and characterised. However, not all types of anaerobic halophi ...
pdf file
pdf file

... upon addition of respiratory substrates to mitochondria. It is shown that the rate and extent of membrane potential generated by succinate (plus rotenone) addition to mitochondria were unaffected by treatment with 5 lM (20 nmol/mg prot) AEA. ADP addition at the steady-state caused an atractyloside a ...
Site-directed mutagenesis of key amino acids in the active site of
Site-directed mutagenesis of key amino acids in the active site of

... AS produces an α-glucan from sucrose – without any participation of nucleotide-activated sugars, like the glucansucrases from lactic acid bacteria which belong to family 70 of glycoside hydrolases (DAVIES & HENRISSAT, 1995; COUTINHO & HENRISSAT, 1999) – it is not classified in the same family. Indee ...
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Effect  of  low  glycogen  on ... metabolism  in  human  muscle  during ...
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... (AMP deaminase) during the contraction. The larger increases in ADP and AMP during LG exercise are considered necessary to activate phosphofructokinase, the TCA cycle, and oxidative phosphorylation under conditions in which glycolysis does not provide adequate substrate for formation of acetyl CoA a ...
Citrate metabolism in lactic acid bacteria
Citrate metabolism in lactic acid bacteria

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... ~3C/1~C ratios in the various classes of metabolites. It is these differences which permit us to determine which substrate is utilized by respiring potato discs during any stage of disc aging. The procedure first requires determination of the ~nC/~2C ratios of the classes of endogenous metabolites w ...
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... is a key step in muscle glycolysis (9), catalyzing the transformation of fructose-6-phosphate (F6P) to fructose- 1,6-diphosphate (Fl ,6P2), a process that is allosterically regulated by several metabolites (9). Under clamp conditions of euglycemia and hyperinsulinemia, glucose clearance in patients ...
1111138443_282429
1111138443_282429

... © 2012 Delmar Cengage Learning. All Rights Reserved. May not be scanned, copied, duplicated, or posted to a publicly accessible website, in whole or in part. ...
Analysis of Honey Samples - Research Commons@Waikato
Analysis of Honey Samples - Research Commons@Waikato

... to be identified as the author of the thesis, and due acknowledgement will be made to the author where appropriate. You will obtain the author’s permission before publishing any material from the thesis. ...
The monocarboxylate transporter family
The monocarboxylate transporter family

... A new class of specific and high-affinity inhibitors of MCT1 have recently been developed by AstraZeneca with Ki values in the nM region (17, 18). We have confirmed the potent inhibition of MCT1-mediated L-lactate transport into rat erythrocytes by one of these inhibitors, AR-C155858, and determined a ...
The optimal dietary DL-methionine on growth performance
The optimal dietary DL-methionine on growth performance

... methionine supplemented groups and the control after 10 weeks of the feeding trial. Body composition. There was no significant difference on body composition and amino acid profile between dietary methionine supplemented group and the control (Tables 4 and 5). The dietary was formulated with concent ...
Perry et al., 2008
Perry et al., 2008

... The greater mitochondrial volume also improves the sensitivity of mitochondria to increases in free ADP (ADPf) at the onset of exercise, accelerating oxidative metabolism and phosphorylation and reducing the need for substrate phosphorylation from phosphocreatine degradation and glycogen use with la ...
Chapter 10
Chapter 10

... • Two electrons and one proton are transferred to NAD+ to form NADH • The bond between the a and b carbons is broken by a thiolase and a two-carbon fragment is transferred to a second acetyl CoA (FA-5) © 2012 Pearson Education, Inc. ...
FREE Sample Here
FREE Sample Here

... 19. A molecule that dissociates in water and gives off hydrogen ions is a(n) A) salt. B) acid. C) base. D) buffer. E) solvent. Answer: B Reference: Chemical Composition and Life Processes Degree of Difficulty: Medium 20. The higher the number on the pH scale, A) the higher the hydrogen ion concentra ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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