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09LecturePresentation
09LecturePresentation

... • In the absence of O2, glycolysis couples with fermentation or anaerobic respiration to produce ATP • Anaerobic respiration uses an electron transport chain with an electron acceptor other than O2, for example sulfate • Fermentation uses phosphorylation instead of an electron transport chain to gen ...
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Macromolecules II PDF

amino acids
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... • A compact and globular structural unit of a protein is often called as a domain (i.e. pearls on a string) • The size of a domain ranges from 30 to 400 amino acid residues. • Different proteins can have a similar or the same domain. • Domain is a structural working unit of a protein for the common ...
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... Amino acids are organic compounds that contain amine (-NH2) and carboxyl (-COOH) functional groups, as well as a side-chain (R group) which confers uniqueness to each amino acid. The main elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen, although other elements can be found in so ...
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... C) endergonic reactions can be fueled by coupling them with the hydrolysis of high-energy phosphate bonds in ATP. D) the regeneration of ATP from ADP can be fueled by coupling it with endergonic reactions. E) ATP is a disposable form of chemical energy, used once and then discarded by the cell. Answ ...
Chapter 2 - Chemical Engineering - Michigan Technological University
Chapter 2 - Chemical Engineering - Michigan Technological University

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... cellular role of ATP is as a "short term" energy transfer device for the cell. The hydrolysis reactions that liberate one or more of ATP's phosphates are exergonic and many, many cellular proteins have evolved to interact with ATP in ways that help to facilitate the transfer of energy from hydrolysi ...
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Effect of dietary administration of lipoic acid on protein

... or human cells in culture and, where assayed, earlier senescence. I hypothesize that DNA damage and late onset disease are a consequence of a triage allocation response to micronutrient shortage. 1) Episodic shortage of micronutrients were common throughout evolution. 2) natural selection favors sho ...
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Protein - DNA interaction in chromatin

... DNA has three primary attributes that allow it to be far better than RNA at encoding genetic information. First, it is normally double-stranded, so that there are a minimum of two copies of the information encoding each gene in every cell. Second, DNA has a much greater stability against breakdown t ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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