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Pharmacokinetics lecture 10
Pharmacokinetics lecture 10

... extravascular doses Assume the same dose of a drug is administered on two occasions to the same individual. Either different dosage forms or routes of administration are used on the two occasions. ...
CHAPTER 13: ENDOCRINE SYSTEM
CHAPTER 13: ENDOCRINE SYSTEM

... consist of 4 small glands; are located within the thyroid gland; produce a hormone called Parathyroid Hormone (PTH): a. release of PTH is stimulated by decreased blood calcium levels; b. PTH targets bone cells (activates osteoclasts to resorb bone), proximal convoluted tubules (causes PCT’s to reabs ...
Hormones and the Endocrine System
Hormones and the Endocrine System

... act within an org., in cells adjacent to where they are produced ...
Principles of Endocrinology
Principles of Endocrinology

... • neuroendocrine reflex - hormone release in response to nervous system signals • suckling infant stimulates nerve endings  hypothalamus  posterior lobe  oxytocin  milk ejection ...
presentation source
presentation source

... • Testes --> testosterone (Starts in fetus --> development of male sex organs & descent of testes. At puberty --> secondary male sexual characteristics. • Ovaries --> estrogens (e.g. 17-beta-estradiol) & progesterone --> secondary female sexual characteristics. Also play a role in the reproductive c ...
Growth hormone
Growth hormone

... High plasma concentration of any steroid with glucocorticoid effect prevents release of corticotrophin releasing hormone and so of ACTH, lack of which in turn results in adrenocortical hypofunction. This is the reason why catastrophe may follow sudden withdrawal of steroid therapy in the chronicall ...
Presentation
Presentation

... 6. How does a hormone recognize its target cells from the other cells it comes in contact with? ...
Biology 416K Summer 2002
Biology 416K Summer 2002

... Which of the following test results would support this diagnosis? a. low blood concentration of estrogen b. low blood concentration of progesterone c. low blood concentration of gonadotropin-releasing hormone d. decreased size of both ovaries viewed by sonogram e. enlarged size of the pituitary glan ...
Endocrine System - El Camino College
Endocrine System - El Camino College

... Mechanism of Hormonal Action – Peptide/Protein (hydrophilic) hormones bind with a membrane receptor stimulate a membrane enzyme Mechanism of Hormonal Action – Steroid/Thyroid (hydrophobic) hormones diffuse into the cells bind to a receptor protein mostly inside nucleus. Endocrine Gland Stimulus: 3-k ...
Endocrine Diseases
Endocrine Diseases

... in transient or permanent hypopituitarism. Octreotide-a somatostatin (somatotropin releaseinhibiting factor) analog. Suppresses GH secretion; used in patients who continue to have excessive GH release post-op; very expensive; injectedshrinks some tumors – Dopaminergic agents (cabergoline, oral) use ...
Pharmacology as a tool to dose individualize cancer therapy
Pharmacology as a tool to dose individualize cancer therapy

... 1. What is the optimal starting (labeled) dose for the indicated population? – Historically, the optimal starting dose was the maximal safe dose, usually as determined in phase 1 studies • <1/3 of patients with DLT ...
The Endocrine System - Valhalla High School
The Endocrine System - Valhalla High School

... of flight” response. It prepares your body for rapid physical activity. ...
The Endocrine System - Valhalla High School
The Endocrine System - Valhalla High School

... body. It increases heart rate, breathing rate and increases blood pressure. ...
Endocrine System
Endocrine System

... over many years prior to diagnosis and may include obesity, physical weakness, easily bruised skin, acne, hypertension, and psychological changes. Treatment may include surgery, radiation therapy, chemotherapy, or blockage of hormone production with drugs. ...
chemical coordination and integration
chemical coordination and integration

... It is a primary sex organ. It also produces 2 hormones called estrogen and progesterone Estrogen is produced by ovarian follicles. It is responsible for the development of secondary sexual characteristic features in female. After ovulation the ruptured follicle is converted into a structure called c ...
Lesson 10 - MsBakerGHS
Lesson 10 - MsBakerGHS

... because they can diffuse through the lipid bilayer of cells. Once steroid hormones are inside target cells, they bind to receptor proteins, which can activate specific genes, causing changes in the cells such as cell growth. ...
hormone
hormone

... • A hormone is a chemical signal produced to send messages around the body  it typically acts a distant site, carried by blood ...
hypothalamic-pituitary axis
hypothalamic-pituitary axis

... – Interstitial cells – estrogen, androgens, progestins – Inhibited by estrogen ...
PACKAGE INSERT TEMPLATE FOR LACTULOSE Brand or Product
PACKAGE INSERT TEMPLATE FOR LACTULOSE Brand or Product

... Flatulance may occur during the first few days of treatment. As a rule it disappears after a couple of days. Nausea and vomiting has been reported. When dosages higher than instructed are used, abdominal pain and diarrhea may occur. In such a case the dosage should be decreased. If high doses(normal ...
bio identical hormones - Riverton Healthcare For Women
bio identical hormones - Riverton Healthcare For Women

... some kind of fountain of youth. What about bioidentical hormones for breast cancer patients? The pendulum has swung so far that today, very few doctors will prescribe any type of HRT — synthetic or bioidentical — for women who have had breast cancer or even a family history of breast cancer. In fact ...
ENDOCRINE SYSTEM THE PITUITARY GLAND
ENDOCRINE SYSTEM THE PITUITARY GLAND

... the releasing organ (if applicable, specify if from the medulla or cortex), name of the hormone, and it’s general function. ...
Pituitary lecture slides
Pituitary lecture slides

... synthesis of sex steroids by the ovary Male: LH controls testosterone production p production p FSH stimulates sperm Deficit: infertility in adult life lack of sexual maturation Excess: precocious puberty See Trinity term Reproduction lectures ...
patient group direction (pgd)
patient group direction (pgd)

... Undiagnosed abnormal vaginal bleeding ...
Thyroid Hormones
Thyroid Hormones

... Endocrine hormones are endogenous chemical mediators that are made at one site, enter the bloodstream, and affect the function of distant organ or of an entire organism ◦ the “wi-fi internet of the human body” ...
Jenny Yin Endocrine System Maintain homeostasis Local Hormones
Jenny Yin Endocrine System Maintain homeostasis Local Hormones

... Lipid-soluble molecules are able to pass across membranes because they can mix with the phospholipids found in the membrane. Steroid hormones exert their action by: Being lipid soluble, steroid hormones can cross the plasma and nuclear membrane of a cell, where they may exert their effect on the exp ...
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Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system. Almost all methods are composed of steroid hormones, although in India one selective estrogen receptor modulator is marketed as a contraceptive. The original hormonal method—the combined oral contraceptive pill—was first marketed as a contraceptive in 1960. In the ensuing decades many other delivery methods have been developed, although the oral and injectable methods are by far the most popular. Altogether, 18% of the world's contraceptive users rely on hormonal methods. Hormonal contraception is highly effective: when taken on the prescribed schedule, users of steroid hormone methods experience pregnancy rates of less than 1% per year. Perfect-use pregnancy rates for most hormonal contraceptives are usually around the 0.3% rate or less. Currently available methods can only be used by women; the development of a male hormonal contraceptive is an active research area.There are two main types of hormonal contraceptive formulations: combined methods which contain both an estrogen and a progestin, and progestogen-only methods which contain only progesterone or one of its synthetic analogues (progestins). Combined methods work by suppressing ovulation and thickening cervical mucus; while progestogen-only methods reduce the frequency of ovulation, most of them rely more heavily on changes in cervical mucus. The incidence of certain side effects is different for the different formulations: for example, breakthrough bleeding is much more common with progestogen-only methods. Certain serious complications occasionally caused by estrogen-containing contraceptives are not believed to be caused by progestogen-only formulations: deep vein thrombosis is one example of this.
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