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Immunity and Gastrointestinal Disease: A Role for Lymphatic Vessels
Immunity and Gastrointestinal Disease: A Role for Lymphatic Vessels

... may function to increase the delivery of dendritic cells and antigenpresenting cells to the lymph nodes to enhance the adaptive immune response, however this has not been proven. Whether these new lymphatic vessels improve drainage to the lymph nodes is still under debate. A study reporting that a l ...
Treatment of Hepatitis C in Patients with Renal
Treatment of Hepatitis C in Patients with Renal

... Hepatitis C Treatment Experience with Chronic Renal Disease Peginterferon and Ribavirin-Based Therapy in Patients with Renal Disease: Renal insufficiency, regardless of the cause, has created problems with the use of peginterferon and ribavirin therapy for HCV, since the kidney plays a role in the ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... This Study Was Conducted From 2011 To 2014 In The Mortuary Of Gandhi Medical College, Secunderabad, Telangana State, India With Sudden Cardiac Death And Death Due To Myocardial Infarction. The Hearts Of 16 Patients (5 Women, 11men) Were Collected At Autopsy Within 8-10 Hrs After Death. Inclusion Cri ...
Comorbidities of hidradenitis suppurativa (acne inversa)
Comorbidities of hidradenitis suppurativa (acne inversa)

... and COCHRANE data bases using the search terms “hidradenitis,” “Verneuil” and “acne inversa.” First, publications, which referred to a coincidence of HS with other diseases, were selected. Subsequently, publications, whose patients met the diagnostic criteria shown in Table 1,27 were only included i ...
Occurrence and Control of Strawberry Powdery Mildew in Al
Occurrence and Control of Strawberry Powdery Mildew in Al

... with the fungus under growth room conditions. Disease incidence and severity were 46.7% and 50.8% in cv. Albion and significantly different from that (1.6% and 5.2%, respectively) in cv. Camarosa. In vitro leaflet bioassays and a runner-tip plantlet experiment were done to assess the influence of so ...
effect of powdery mildew on mango chlorophyll content and disease
effect of powdery mildew on mango chlorophyll content and disease

... Mango (Mangifera indica L.) is universally one of the most popular edible fruit crops. In Egypt, the areas cultivated reached 222838 feddans (169068 feddan as fruiting trees) with an approximate production of 598084 metric tons (Anonymous, 2011). Powdery mildew is one of the most serious diseases of ...
Z-DNA-specific Antibodies in Human Systemic
Z-DNA-specific Antibodies in Human Systemic

... are organized in a zig-zag pattern rather than a smooth spiral. One might then expect that in addition to a group of antibodies that see the zig-zag backbone, antibodies that recognize bases might also react with the surface of the Z-helix. This paper establishes that naturally occurring antibodies ...
Host responses in periodontal diseases: a preview
Host responses in periodontal diseases: a preview

... hyperglycemia may lead to chronically activated innate immunity and chronic inflammation in the periodontium by either blocking or suppressing pathways of resolution. Nassar et al. (13) examined the role of innate immunity, inflammation and resolution of inflammation as essential components in the d ...
Seborrheic dermatitis: Etiology, risk factors, and treatments: Facts and controversies ⁎
Seborrheic dermatitis: Etiology, risk factors, and treatments: Facts and controversies ⁎

... SD skin, and on the therapeutic response seen to antifungal agents.11 Improvement in SD is accompanied by reduction in the yeast on the scalp, whereas recolonization leads to disease recurrence.41–43 A causative link between SD and Malassezia was further supported by the finding that patients with d ...
Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus

... bound by complement, and quickly engulfed and disposed of by “housekeeping” macrophages,” and their intercellular contents are not available for immune surveillance.  Dysregulation of this step can lead to induction of SLE in two ways Increased apoptosis - If clearance of apoptotic material is not ...
Treatment of Hepatitis C in Patients with Renal Impairment
Treatment of Hepatitis C in Patients with Renal Impairment

... Hepatitis C Treatment Experience with Chronic Renal Disease Peginterferon and Ribavirin-Based Therapy in Patients with Renal Disease: Renal insufficiency, regardless of the cause, has created problems with the use of peginterferon and ribavirin therapy for HCV, since the kidney plays a role in the c ...
Periodontal disease associated to systemic genetic disorders
Periodontal disease associated to systemic genetic disorders

... severe form with patterns of both horizontal and vertical bone resorption, and in accordance to the presence of bacterial plaque. Dental mobility has been shown to be due to periodontitis, and is not attributable to the primary condition of the syndrome (4). In the case of Ehler-Danlos syndrome, per ...
Invasive Group B Streptococcal Disease: The Emergence of
Invasive Group B Streptococcal Disease: The Emergence of

... United States and cause significant pregnancy-related morbidity affecting ~ 50,000 women each year in the United States [1-4]. Recently, it has been recognized that GBS are also an important cause of invasive disease in nonpregnant adults [5]. GBS disease in nonpregnant adults most commonly affects ...
Toward an Inclusive, Congruent, and Precise Definition of
Toward an Inclusive, Congruent, and Precise Definition of

... that leads to phenotypes in which autoinflammation is combined with susceptibility to infections have recently been described (14–16). One such disease is autoinflammation and PLCγ2associated antibody deficiency and immune dysregulation (APLAID), caused by missense mutations in (the gene) PLCG2. Thi ...
MANAGEMENT OF POWDERY MILDEW DISEASE OF RAMBUTAN
MANAGEMENT OF POWDERY MILDEW DISEASE OF RAMBUTAN

... Farmers did not pay much attention to this disease, as it was not a serious problem in year 2000. It can be assumed that the farmer’s ignorance led to the severe outbreak of powdery mildew in year 2001. Climatic conditions i.e. intermittent showers with high temperature, very high humidity and less ...
Cutaneous Signs of Systemic Disease (1)
Cutaneous Signs of Systemic Disease (1)

...  The nodules appear SYMETRICALLY and BILATERALLY mainly on the anterior shins  Scattered lesions can also be found on the upper legs, extensor arms, neck, and rarely face  Lesions resolve only with a bruise and DO NOT ulcerate or drain Additionally, patients may present with malaise, leg edema, a ...
Probiotics Applications in Autoimmune Diseases
Probiotics Applications in Autoimmune Diseases

... from the diseases themselves as well as complications. Even though the causes of AD have been postulated to be genetic and environmental, the actual triggers remain poorly defined [3]. Genetic predisposition contribute to about 30% of AD while 70% to environmental factors such as infections (e.g., v ...
IgG and IgA Antibody Profiling with the PEPperCHIP
IgG and IgA Antibody Profiling with the PEPperCHIP

... unlikely. The same applied to the IgA responses against epitopes of hepatitis C virus without any accompanying IgG response. In contrast to this, an IgA response against Helicobacter pylori appeared to be reasonable due to its high prevalence particularly in the gastrointestinal tract. Diagnostic Te ...
What causes polio? What are the signs and symptoms of polio? How
What causes polio? What are the signs and symptoms of polio? How

... What are the signs and symptoms of polio? Around 95 per cent of polio cases are mild and do not have any symptoms. Otherwise, between three days and three weeks after the infection a child might get a slight fever, sore throat and experience vomiting. This may pass within a few days but sometimes it ...
Immunoflourescence in dermatopathology
Immunoflourescence in dermatopathology

... The best site and evolution time of skin lesions to perform biopsy for direct immunofluorescence examination (DIF) depend on the disease under investigation. Generally, the biopsy should have an appropriate extension (4 mm punch) and depth that involves both the epidermis and dermis in sufficient pr ...
Acute-on-chronic liver failure: an update
Acute-on-chronic liver failure: an update

... has been dichotomised in compensated and decompensated, and the transition to decompensated cirrhosis happens when any of the following hallmarks occurs: presence of ascites, variceal haemorrhage and/or hepatic encephalopathy (HE).2 Once cirrhosis transitions from the compensated to the decompensate ...
Humoral Sensitization Against Rejected Grafts
Humoral Sensitization Against Rejected Grafts

... for the cellular alloimmune responses.6 It is well known that patients receiving a second graft show lower graft survival rates than nonsensitized recipients, even though sensitive crossmatch techniques facilitate second transplants with a lower risk of early graft loss.7 Therefore, an accurate anal ...
Antibiotic Prophylaxis Clinical Practice Guideline
Antibiotic Prophylaxis Clinical Practice Guideline

... Statement of the Problem  Infective endocarditis is an infection of the endocardium, most commonly caused by a gram‐positive  coccus, although gram‐negative bacillus and fungus can also produce the disease. Before the  introduction of antibiotics, endocarditis was, almost without exception, fatal. M ...
If You Google Auto-Immune Disease, You`ll Find
If You Google Auto-Immune Disease, You`ll Find

... where your body is destroying its own tissue. There tends to be an unnecessary mystery around auto-immune disorders and like many named diagnoses, we are sometimes lead to believe they are curses we have inherited from our ancestors or unexplainable phenomena that have no known cure. I will try to r ...
Lyme Disease? - Nutri-Spec
Lyme Disease? - Nutri-Spec

... Both the skin lesions and the myalgia tend to migrate. Phase 2: is experienced by only about 20% of the people infected. It is a neurological phase that includes many diverse neuritis symptoms and can involve several different spinal tracts. Phase 3: is the arthritic phase which can last from severa ...
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Neuromyelitis optica

Neuromyelitis optica (NMO), also known as Devic's disease or Devic's syndrome, is a heterogeneous condition consisting of the simultaneous inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis). It can be monophasic or recurrent.Currently at least two different causes are proposed based on the presence of autoantibodies against AQP4. AQP4+ NMO is currently considered an autoimmune disease (autoimmune astrocytopathy, or autoimmune astrocytic channelopathy) in which a person's own immune system attacks the astrocytes of the optic nerves and spinal cord. The cause of the AQP4- variants is unknown.Although inflammation may also affect the brain, the lesions are different from those observed in the related condition, multiple sclerosis. Spinal cord lesions lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation (including blindness), and/or bladder and bowel dysfunction.Devic's disease is now studied along a collection of similar diseases called ""Neuromyelitis optica spectrum diseases"". Some cases of this spectrum resemble multiple sclerosis (MS) in several ways, but require a different course of treatment for optimal results.In 2004, NMO-IgG (currently known as Anti-AQP IgG) was first described leading to the distinction between positive and negative cases.In Anti-AQP positive variants, CNS astrocytes, which are the basis for the glymphatic system are the target of the autoimmune attack. NMO-IgG-negative cases are less understood. It seems currently that astrocytes are spared in these IgG negative cases
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