prolactin and autoimmune diseases prolakt
... responses to sheep red blood cells (35ô. In another study, mice injected with 100 or 200 micrograms of bovine prolactin had increased production of anti-sheep red blood cell antibodies. In contrast, there was no effect on antibody production in mice injected with a 400 microgram dose (36). Bryant an ...
... responses to sheep red blood cells (35ô. In another study, mice injected with 100 or 200 micrograms of bovine prolactin had increased production of anti-sheep red blood cell antibodies. In contrast, there was no effect on antibody production in mice injected with a 400 microgram dose (36). Bryant an ...
Pemphigoid diseases: Pathogenesis, diagnosis, and treatment
... found no relationship between a positive BP230 ELISA result and disease extent or presence of mucosal involvement [39], with regard to this specific finding, the study by Roussel et al. [40] showed the opposite finding. Two other studies suggested that anti-BP230 antibodies may be preferentially ass ...
... found no relationship between a positive BP230 ELISA result and disease extent or presence of mucosal involvement [39], with regard to this specific finding, the study by Roussel et al. [40] showed the opposite finding. Two other studies suggested that anti-BP230 antibodies may be preferentially ass ...
Narrative Review: The Role of Th2 Immune Pathway Modulation in
... Institute–sponsored Severe Asthma Research Program identified both frequent and severe exacerbations of asthma as hallmarks of severe disease. In addition, severe asthma is associated with comorbid conditions, such as obesity, hypertension, sinusitis, and type 2 diabetes (2, 5). This small subgroup ...
... Institute–sponsored Severe Asthma Research Program identified both frequent and severe exacerbations of asthma as hallmarks of severe disease. In addition, severe asthma is associated with comorbid conditions, such as obesity, hypertension, sinusitis, and type 2 diabetes (2, 5). This small subgroup ...
Monoclonal Antibodies for Therapeutic Use: Specific Characteristics
... oncology, where MoAb are often studied as second- or third-line therapy, especially in the early phases of clinical development. Patients are at an advanced stage of disease and will have already received treatment with cytotoxic chemotherapy which may have affected their cell immunity. The MoAb sho ...
... oncology, where MoAb are often studied as second- or third-line therapy, especially in the early phases of clinical development. Patients are at an advanced stage of disease and will have already received treatment with cytotoxic chemotherapy which may have affected their cell immunity. The MoAb sho ...
Cholesteatoma Easily Missed? Cholesteatoma Mahmood F Bhutta
... In primary care, cholesteatoma should be suspected in an ear with recurrent or persistent otorrhoea that fails to settle fully with treatment. In general practice such symptoms are more often the result of recurrent otitis externa or recurrent otitis media,10 but only a full visualisation of the tym ...
... In primary care, cholesteatoma should be suspected in an ear with recurrent or persistent otorrhoea that fails to settle fully with treatment. In general practice such symptoms are more often the result of recurrent otitis externa or recurrent otitis media,10 but only a full visualisation of the tym ...
Characterization of Legionella pneumophila isolates from patients in
... The mean and median age of the 85 legionellosis patients (72 males, 10 females and 3 unknown cases) was 59.2 and 60 years, respectively (range 0–81; excluding the three patients whose ages were unknown). It has been shown previously that many more males than females contract legionellosis (Infectiou ...
... The mean and median age of the 85 legionellosis patients (72 males, 10 females and 3 unknown cases) was 59.2 and 60 years, respectively (range 0–81; excluding the three patients whose ages were unknown). It has been shown previously that many more males than females contract legionellosis (Infectiou ...
Progress in Autoimmune Diseases Research
... autoimmune diseases, patients face a lifetime of illness and treatment. They often endure debilitating symptoms, loss of organ function, reduced productivity at work, and high medical expenses. And, because most of these diseases disproportionately afflict women, and are among the leading causes of ...
... autoimmune diseases, patients face a lifetime of illness and treatment. They often endure debilitating symptoms, loss of organ function, reduced productivity at work, and high medical expenses. And, because most of these diseases disproportionately afflict women, and are among the leading causes of ...
Consensus Recommendations for the use of Immunoglobulin Replacement Therapy in Immune Deficiency
... gut by vaccine-derived poliovirus and patients may continue to excrete large amounts of virus for years.21 ...
... gut by vaccine-derived poliovirus and patients may continue to excrete large amounts of virus for years.21 ...
Lymphoid follicles in (very) severe COPD: beneficial or harmful? REVIEW
... Whereas one of the first reports on the presence of B-cell follicles in COPD dates from 1992 [13], quite recently attention has been redrawn to a possible role of B-cells. An increase of small airways containing B-cell follicles was found in patients with severe COPD compared to normal subjects and ...
... Whereas one of the first reports on the presence of B-cell follicles in COPD dates from 1992 [13], quite recently attention has been redrawn to a possible role of B-cells. An increase of small airways containing B-cell follicles was found in patients with severe COPD compared to normal subjects and ...
acute viral myocarditis: current concepts in diagnosis and treatment reviews
... and to rule out other causes of heart failure, such as valvular, usually good in fulminant myocarditis if patients survive the congenital, or amyloid heart disease. Classic findings include initial phase. This is in contrast to acute myocarditis in which global hypokinesis with or without pericardia ...
... and to rule out other causes of heart failure, such as valvular, usually good in fulminant myocarditis if patients survive the congenital, or amyloid heart disease. Classic findings include initial phase. This is in contrast to acute myocarditis in which global hypokinesis with or without pericardia ...
Impact of Anti-Oxidized Low- Density Lipoprotein
... of guanine is linked to the 5-methyl group of an adjacent 3’-thymine [24-26]. The majority of these ROS species are produced at a low level by normal aerobic metabolism, and normal defense mechanisms of the cells destroy most of them. Normally, any lesion to cells is constantly repaired. However, un ...
... of guanine is linked to the 5-methyl group of an adjacent 3’-thymine [24-26]. The majority of these ROS species are produced at a low level by normal aerobic metabolism, and normal defense mechanisms of the cells destroy most of them. Normally, any lesion to cells is constantly repaired. However, un ...
Vortrag - Institut für Pathologie Prof. Dr. Klaus Richter, Hannover
... represents one of the most difficult tasks confronting pathologists. The reasons for this are: · The relatively low frequency of liver biopsies. Due to improvements in clinical, laboratory chemical and molecular biological methods, fewer liver biopsies are performed in many cases. Some clinicians be ...
... represents one of the most difficult tasks confronting pathologists. The reasons for this are: · The relatively low frequency of liver biopsies. Due to improvements in clinical, laboratory chemical and molecular biological methods, fewer liver biopsies are performed in many cases. Some clinicians be ...
The Role and Immunobiology of Eosinophils in the Respiratory
... First described by Charles B. Carrington in the New England Journal of Medicine in 1969, chronic eosinophilic pneumonia (CEP) is a rare disorder, with many reports of this illness being limited to case studies [26, 27]. Though the exact etiology is unknown, the disease is often associated with a hig ...
... First described by Charles B. Carrington in the New England Journal of Medicine in 1969, chronic eosinophilic pneumonia (CEP) is a rare disorder, with many reports of this illness being limited to case studies [26, 27]. Though the exact etiology is unknown, the disease is often associated with a hig ...
Clinical Applications of Diffusion Imaging in the Spine
... There is, however, a range of current and potential applications for DWI in the spine. As in the brain, the sensitivity of DWI to ischemic damage in the spinal cord may provide early identification of infarction. DWI has been exploited for its ability to detect and characterize lesions of the spinal ...
... There is, however, a range of current and potential applications for DWI in the spine. As in the brain, the sensitivity of DWI to ischemic damage in the spinal cord may provide early identification of infarction. DWI has been exploited for its ability to detect and characterize lesions of the spinal ...
Monoclonal Antibody Pharmacokinetics and
... The majority of marketed antibodies are labeled for intravenous (IV) administration; however, several antibodies have been approved for extravascular administration. For example, certolizumab pegol, adalimumab, efalizumab, and omalizumab are all approved for subcutaneous (SC) administration. Paliviz ...
... The majority of marketed antibodies are labeled for intravenous (IV) administration; however, several antibodies have been approved for extravascular administration. For example, certolizumab pegol, adalimumab, efalizumab, and omalizumab are all approved for subcutaneous (SC) administration. Paliviz ...
Egyptian Dermatology Online Journal Vol. 6 No 4: 1, June 2010 A
... the four cases of superficial white onychomycosis (SWO), the isolate obtained from only one culture positive case was T. mentagrophyte. This is the commonest dermatophyte implicated in the etiology of superficial white onychomycosis (SWO) [1]. T. tonsurans and T. schoenleinii were isolated in 4% and ...
... the four cases of superficial white onychomycosis (SWO), the isolate obtained from only one culture positive case was T. mentagrophyte. This is the commonest dermatophyte implicated in the etiology of superficial white onychomycosis (SWO) [1]. T. tonsurans and T. schoenleinii were isolated in 4% and ...
Combinations of type 1 diabetes, celiac disease and allergy
... The word immunity comes from the Latin word “immunis”, meaning exempt. The immunological science is believed to originate from Jenner who discovered that cowpox could be used as vaccine against human smallpox; however it was not until late 19th century that microorganisms were identified as the caus ...
... The word immunity comes from the Latin word “immunis”, meaning exempt. The immunological science is believed to originate from Jenner who discovered that cowpox could be used as vaccine against human smallpox; however it was not until late 19th century that microorganisms were identified as the caus ...
Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies
... ischemia in the digits, the differential diagnosis includes Reynaud phenomenon. The laboratory differential diagnosis associated with a positive DAT can be challenging, especially given that up to 15% of hospitalized patients may have a positive DAT.7 Other causes of a positive DAT include drug effe ...
... ischemia in the digits, the differential diagnosis includes Reynaud phenomenon. The laboratory differential diagnosis associated with a positive DAT can be challenging, especially given that up to 15% of hospitalized patients may have a positive DAT.7 Other causes of a positive DAT include drug effe ...
Dissertation LeWi Fakultät Humboldt-Universität zu Berlin
... and perform a switch from pro-inflammatory to alternatively activated macrophage phenotypes. Moreover, macrophages are important players in autoimmune reactions in myopathies and might therefore be an interesting target for specific therapies. In the current thesis, three different entities were ana ...
... and perform a switch from pro-inflammatory to alternatively activated macrophage phenotypes. Moreover, macrophages are important players in autoimmune reactions in myopathies and might therefore be an interesting target for specific therapies. In the current thesis, three different entities were ana ...
Parallels between Pathogens and Gluten Peptides in Celiac Sprue
... glutamine-rich regions of gluten proteins (protein depicted as yellow rectangle containing immunotoxic peptide in green, right panel), cause celiac sprue in susceptible individuals (white box; right panel) by evading gastrointestinal proteolysis, invading across the intestinal epithelium by unknown ...
... glutamine-rich regions of gluten proteins (protein depicted as yellow rectangle containing immunotoxic peptide in green, right panel), cause celiac sprue in susceptible individuals (white box; right panel) by evading gastrointestinal proteolysis, invading across the intestinal epithelium by unknown ...
LEPROSY (in Europe)
... donated by the town near Capo Faro (now Lanterna). The establishing act was drawn uo in the Cathedral of S.Lorenzo in the presence of the Arcibishop Siro. The leprosarium was run by a committee partly formed by leprosy patients, a quite usual practice in medieval leprosaria ,and the rector was appoi ...
... donated by the town near Capo Faro (now Lanterna). The establishing act was drawn uo in the Cathedral of S.Lorenzo in the presence of the Arcibishop Siro. The leprosarium was run by a committee partly formed by leprosy patients, a quite usual practice in medieval leprosaria ,and the rector was appoi ...
What`s New in Eosinophilic Esophagitis and Proton Pump Inhibitor
... • RCTs show that topical steroids significantly reduce esophageal eosinophil levels • Most patients experience symptomatic relief during treatment with steroids • Symptoms recur frequently when steroids are stopped • Limited data on efficacy and safety of long-term steroid therapy for EoE ...
... • RCTs show that topical steroids significantly reduce esophageal eosinophil levels • Most patients experience symptomatic relief during treatment with steroids • Symptoms recur frequently when steroids are stopped • Limited data on efficacy and safety of long-term steroid therapy for EoE ...
The use of antibodies in the treatment of infectious diseases
... their high specificity. In contrast to the shotgun approach ...
... their high specificity. In contrast to the shotgun approach ...
ACUTE ANTERIOR UVEITIS AND HLA-B27: INFECTIOUS BACKGROUND, SYSTEMIC INFLAMMATION,
... (TNF)-α production in response to bacterial lipopolysaccharide (LPS) was studied using whole blood culture assay. The levels of TNF-α in culture supernatants and soluble interleukin-2 receptor (sIL-2R) in serum were determined by chemiluminescent immunoassay (Immulite). The monocyte surface express ...
... (TNF)-α production in response to bacterial lipopolysaccharide (LPS) was studied using whole blood culture assay. The levels of TNF-α in culture supernatants and soluble interleukin-2 receptor (sIL-2R) in serum were determined by chemiluminescent immunoassay (Immulite). The monocyte surface express ...
Three cases of oral syphilis – an overview
... of syphilis may be classified according to the stage of the disease. There are numerous less common extra-oral manifestations outside the scope of this article. An example of the latter that may be relevant to dentists is the development of cranial nerve palsies in tertiary syphilis. The symptoms of ...
... of syphilis may be classified according to the stage of the disease. There are numerous less common extra-oral manifestations outside the scope of this article. An example of the latter that may be relevant to dentists is the development of cranial nerve palsies in tertiary syphilis. The symptoms of ...