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Histopathology of bronchiectasis
Histopathology of bronchiectasis

... This classification is now probably unsatisfactory and of little pathological significance; although the distribution of changes may provide a clue to the underlying aetiology. Post-infective bronchiectasis is traditionally the most common underlying cause, is most often basal and may be confined to ...
Endotypes and phenotypes of chronic rhinosinusitis
Endotypes and phenotypes of chronic rhinosinusitis

... corresponding biomarkers. Different CRS endotypes can be characterized by differences in responsiveness to different treatments, including topical intranasal corticosteroids and biological agents, such as anti–IL-5 and anti-IgE mAb, and can be based on different biomarkers that are linked to underly ...
Can nicotine use alleviate symptoms of psoriasis?
Can nicotine use alleviate symptoms of psoriasis?

... Americans.1 Although psoriasis can manifest at any age, there seem to be 2 peaks in onset: one between the ages of 20 and 30 years, and another between the ages of 50 and 60 years.2 Several clinical types of psoriasis have been described; however, 90% of cases present with plaque psoriasis.3 Previou ...
Full-Text PDF
Full-Text PDF

... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
Acute Kidney Injury: Epidemiology, Diagnosis, Prognosis, and
Acute Kidney Injury: Epidemiology, Diagnosis, Prognosis, and

... proper cut-offs remain to be defined, and their specificity may be compromised by concomitant conditions, for example, plasma NGAL is also elevated in sepsis and in cardiac failure.60,61 The development of studies using biochemical patterns of markers that could anticipate the diagnosis of AKI, assi ...
Colostrum and the Health of Newborn Kids By Jack Mauldin I have
Colostrum and the Health of Newborn Kids By Jack Mauldin I have

... Antibody is a disease-fighting protein. There are other medical names but I will only use the word “antibody” in this article for ease of reading. Antibodies are produced by animals in response to bacteria or bacterial toxins in the body and are very specific for that specific bacteria problem. Bact ...
Arterioscler Thromb Vasc Biol. - Arteriosclerosis, Thrombosis, and
Arterioscler Thromb Vasc Biol. - Arteriosclerosis, Thrombosis, and

... stroke) in the last 93⫾59 days. Plaques were removed from patients with internal carotid artery stenosis ⬎50%. The severity of carotid stenosis was assessed by duplex imaging by the same observer using internationally established criteria.21 Cardiovascular risk factors such as hypertension (systolic ...
Antibodies to Chlamydia trachomatis heat shock proteins in women
Antibodies to Chlamydia trachomatis heat shock proteins in women

... 0.96, not statistically different (χ2 test). The GMT for LPSIgG among patients who had such antibodies was 1142 and 645 among controls, which was a statistically significant difference (P , 0.001, Student’s t-test). The corresponding LPS-IgA mean titres in patients and controls were 205 and 172 resp ...
Extensive tinea corporis due to Trichophyton rubrum on the trunk
Extensive tinea corporis due to Trichophyton rubrum on the trunk

... infection with worldwide distribution. ...
Parasitic Infections of the Appendix as a Cause
Parasitic Infections of the Appendix as a Cause

... initiation. Pathogenetic differences between these two situations seem to be unexplainable. Although most of the intestinal parasites are asymptomatic, they may sometimes present with life threatening complications. Through wide spectrum of complications, parasites may cause primary or secondary inf ...
Warts – Spectra of Different Clinical Presentation Pragya kushwaha , Shruti singh
Warts – Spectra of Different Clinical Presentation Pragya kushwaha , Shruti singh

... According to Kilkenny M et al5 nongenital warts occur most frequently in children & young adults in whom the incidence may exceed 10%. In our study incidence in first decade is 18.49% & in 2 nd decade is 25% which has got good correlation with the above study. Incidence declines with the age of the ...
Seroprevalence of Mycoplasma pneumoniae in HIV
Seroprevalence of Mycoplasma pneumoniae in HIV

... Although studies to determine the prevalence of M. pneumoniae in various parts of the world have been carried out, there is still a paucity of good epidemiological data on the frequency with which atypical pathogens such as M. pneumoniae cause community-acquired pneumonia in India (Shankar et al., 2 ...
Chronic inflammatory disease and its treatment during pregnancy
Chronic inflammatory disease and its treatment during pregnancy

... Current knowledge suggests that the intestinal inflammation develops because of unwarranted immune responses to the microbial flora in genetically susceptible individuals.23 Several genetic susceptibility loci have been identified in patients with IBD, many of them shared by Crohn’s disease and ulce ...
Immunoblot assay for determining the incidence allergens specific
Immunoblot assay for determining the incidence allergens specific

... increased rates of allergic sensitization of persons prone to allergic rhinitis. Subtle changes in social practices, like pet ownership, increasing mobilisation and introduction of new potentially allergen. The results of this study are mostly consistent with the results of other studies made in oth ...
Syphilis Epidemiology
Syphilis Epidemiology

... • The typical primary syphilitic chancre is solitary, indurated, and painless, but many clinical variants occur • Most chancres are genital, oral, or perianal, but may occur anywhere T. pallidum is inoculated • The primary histopathology seen in syphilis is arteritis and periarteritis ...
4. Treatment of pyoderma gangrenosum usually involves systemic
4. Treatment of pyoderma gangrenosum usually involves systemic

... sharply circumscribed violaceous raised edges [1]. Lesions typically affect the lower extremities and the trunk [4]. The varied appearance of these ulcers has led to their recent clinical classification, which includes four prototypic forms of pyoderma gangrenosum: ulcerative, pustular, bullous and ...
Management of CMV: Immune Monitoring, New therapies, Vaccines
Management of CMV: Immune Monitoring, New therapies, Vaccines

... • Prophylaxis and treatment indications for new antivirals will need to be better defined ...
Actinomycosis in Differential Diagnosis of Cervicofacial Mass: A
Actinomycosis in Differential Diagnosis of Cervicofacial Mass: A

... sensitive to many antibiotics. Actinomyces are in the normal flora of the gastrointestinal tract and mouth. These microorganisms are usually non-virulent in nature, however an interruption of the protective mucosal barrier, and alteration of the resident microbial flora play a crucial role in infect ...
Inflammation Aggravates Disease Severity in Marfan Syndrome Patients
Inflammation Aggravates Disease Severity in Marfan Syndrome Patients

... markers in blood would correlate to aortic phenotype in MFS patients. TGF-b, C-Reactive Protein (CRP; a well established aspecific marker of systemic inflammation) and several prominent cytokines were measured in plasma of our MFS patient group (Table S1). The tested cytokines are pro- or anti-infla ...
Morphology of autoimmune hepatitis - pathologie
Morphology of autoimmune hepatitis - pathologie

... Lobular single-cell necroses. Intralobular necroses of hepatocytes occur that are characterized by acidophilia, cell debris and isolated inflammatory cells. In the vicinity, the above-mentioned activated Kupffer cells occur in increased numbers and always migrate towards cellular damage. Kupffer cel ...
Scabies Incognito Presenting as a Subcorneal Pustular Dermatosis
Scabies Incognito Presenting as a Subcorneal Pustular Dermatosis

... an elderly woman that presented as subcorneal pustular dermatosis-like eruption. We assumed that this case could be reported because it is an unusual event among the general population. In conclusion, the differential diagnoses of skin diseases should be considered when diagnosing scabies. Thus, unn ...
Autoimmunity to glomerular antigens in
Autoimmunity to glomerular antigens in

... U-tests, and the relationship between antibody levels was examined by Kendall's rank correlation. The tabulated results are expressed as means & SD. RESULTS Antiglomerular antibodies ...
O A RIGINAL RTICLES
O A RIGINAL RTICLES

... in a small group of patients with documented pneumococcal disease, the concentrations of circulating IgG antibodies to both pneumolysin and pneumococcal capsular polysaccharide (PPS) measured at the time of hospital admission were significantly lower than those of a group of age-matched control subj ...
Induction of IgA Circulating Immune Complexes after
Induction of IgA Circulating Immune Complexes after

... test units). By definition, values greater than 2 test units above this mean are considered to be elevated. Assay variability of the Raji cell IgA eIe which is clearly above the normal range, and signifitest on an individual day was established by running the same sample cantly different from base l ...
ACUTE EPIDIDYMITIS: A WORK
ACUTE EPIDIDYMITIS: A WORK

... Nonspecific epididymitis was secondary to an unidentifiable etiologic agent or event. Traumatic epididymitis was due to a reflux of sterile urine down the vas, leading to a chemical inflammation.' However, over the past 20 years, with the improvement in microbiologic culture technology, especially f ...
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Neuromyelitis optica

Neuromyelitis optica (NMO), also known as Devic's disease or Devic's syndrome, is a heterogeneous condition consisting of the simultaneous inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis). It can be monophasic or recurrent.Currently at least two different causes are proposed based on the presence of autoantibodies against AQP4. AQP4+ NMO is currently considered an autoimmune disease (autoimmune astrocytopathy, or autoimmune astrocytic channelopathy) in which a person's own immune system attacks the astrocytes of the optic nerves and spinal cord. The cause of the AQP4- variants is unknown.Although inflammation may also affect the brain, the lesions are different from those observed in the related condition, multiple sclerosis. Spinal cord lesions lead to varying degrees of weakness or paralysis in the legs or arms, loss of sensation (including blindness), and/or bladder and bowel dysfunction.Devic's disease is now studied along a collection of similar diseases called ""Neuromyelitis optica spectrum diseases"". Some cases of this spectrum resemble multiple sclerosis (MS) in several ways, but require a different course of treatment for optimal results.In 2004, NMO-IgG (currently known as Anti-AQP IgG) was first described leading to the distinction between positive and negative cases.In Anti-AQP positive variants, CNS astrocytes, which are the basis for the glymphatic system are the target of the autoimmune attack. NMO-IgG-negative cases are less understood. It seems currently that astrocytes are spared in these IgG negative cases
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